{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:06:15Z","timestamp":1793034375807,"version":"4.5.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41831287"],"award-info":[{"award-number":["41831287"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["19JCZDJC40800"],"award-info":[{"award-number":["19JCZDJC40800"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013142","name":"Key Research and Development Project of Hainan Province","doi-asserted-by":"publisher","award":["19273707D"],"award-info":[{"award-number":["19273707D"]}],"id":[{"id":"10.13039\/501100013142","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["41525013"],"award-info":[{"award-number":["41525013"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["41703088"],"award-info":[{"award-number":["41703088"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["21607016"],"award-info":[{"award-number":["21607016"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["31670509"],"award-info":[{"award-number":["31670509"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005153","name":"China National Funds for Distinguished Young Scientists","doi-asserted-by":"publisher","award":["31870351"],"award-info":[{"award-number":["31870351"]}],"id":[{"id":"10.13039\/501100005153","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.envpol.2020.114399","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T08:41:21Z","timestamp":1584520881000},"page":"114399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"PB","title":["Vancomycin exposure caused opportunistic pathogens bloom in intestinal microbiome by simulator of the human intestinal microbial ecosystem (SHIME)"],"prefix":"10.1016","volume":"265","author":[{"given":"Lei","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjit","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huai","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingliang","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingang","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daqing","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2020.114399_bib1","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1289\/ehp.1206316","article-title":"Human health risk assessment (HHRA) for environmental development and transfer of antibiotic resistance","volume":"121","author":"Ashbolt","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2020.114399_bib2","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.envres.2018.11.040","article-title":"Human health risk assessment of antibiotic resistance associated with antibiotic residues in the environment: a review","volume":"169","author":"Ben","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2020.114399_bib3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/femsre\/fux053","article-title":"Environmental factors influencing the development and spread of antibiotic resistance","volume":"42","author":"Bengtsson-Palme","year":"2018","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.envpol.2020.114399_bib4","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.ijantimicag.2017.03.009","article-title":"Emerging extended-spectrum \u03b2-lactamase-producing Klebsiella pneumoniae causing community-onset urinary tract infections: a case-control-control study","volume":"50","author":"Boix-Palop","year":"2017","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.envpol.2020.114399_bib5","doi-asserted-by":"crossref","DOI":"10.1128\/mSphereDirect.00588-18","article-title":"Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential","volume":"3","author":"Bulow","year":"2018","journal-title":"mSphere"},{"key":"10.1016\/j.envpol.2020.114399_bib6","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat. Methods"},{"key":"10.1016\/j.envpol.2020.114399_bib7","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.meegid.2017.11.015","article-title":"Risk assessment of infected children with Pseudomonas aeruginosa pneumonia by combining host and pathogen predictors","volume":"57","author":"Chen","year":"2018","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.envpol.2020.114399_bib8","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1089\/mdr.2017.0199","article-title":"Antibiotic resistance gene detection in the microbiome context","volume":"24","author":"Do","year":"2018","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.envpol.2020.114399_bib9","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.3389\/fmicb.2019.01206","article-title":"Propionate-producing consortium restores antibiotic-induced dysbiosis in a dynamic in\u00a0vitro model of the human intestinal microbial ecosystem","volume":"10","author":"El Hage","year":"2019","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2020.114399_bib10","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1016\/j.envpol.2017.09.047","article-title":"Validation and application of quantitative PCR assays using host-specific Bacteroidales genetic markers for swine fecal pollution tracking","volume":"231","author":"Fan","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2020.114399_bib11","doi-asserted-by":"crossref","first-page":"5480","DOI":"10.1021\/acs.jafc.7b02049","article-title":"Gastrointestinal simulation model TWIN-SHIME shows differences between human urolithin-metabotypes in gut microbiota composition, pomegranate polyphenol metabolism, and transport along the Intestinal tract","volume":"65","author":"Garcia-Villalba","year":"2017","journal-title":"J.\u00a0Agric. Food Chem."},{"key":"10.1016\/j.envpol.2020.114399_bib12","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/cid\/cix270","article-title":"Gastrointestinal carriage is a major reservoir of Klebsiella pneumoniae infection in intensive care patients","volume":"65","author":"Gorrie","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.envpol.2020.114399_bib13","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1093\/cid\/ciw731","article-title":"Oral vancomycin followed by fecal transplantation versus tapering oral vancomycin treatment for recurrent Clostridium difficile infection: an open-label, randomized controlled trial","volume":"64","author":"Hota","year":"2017","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.envpol.2020.114399_bib14","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1038\/ncomms3151","article-title":"Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota","volume":"4","author":"Hu","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2020.114399_bib15","doi-asserted-by":"crossref","first-page":"30919","DOI":"10.18632\/oncotarget.25778","article-title":"Protection from chemotherapy- and antibiotic-mediated dysbiosis of the gut microbiota by a probiotic with digestive enzymes supplement","volume":"9","author":"Ichim","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.envpol.2020.114399_bib16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dkw383","article-title":"Short- and long-term effects of oral vancomycin on the human intestinal microbiota","volume":"72","author":"Isaac","year":"2017","journal-title":"J.\u00a0Antimicrob. Chemother."},{"key":"10.1016\/j.envpol.2020.114399_bib17","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.anaerobe.2018.02.007","article-title":"Antimicrobial susceptibility testing of Bacteroides fragilis using the MALDI Biotyper antibiotic susceptibility test rapid assay (MBT-ASTRA)","volume":"54","author":"Justesen","year":"2018","journal-title":"Anaerobe"},{"key":"10.1016\/j.envpol.2020.114399_bib18","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1097\/MEG.0000000000001243","article-title":"Comparing fecal microbiota transplantation to standard-of-care treatment for recurrent Clostridium difficile infection: a systematic review and meta-analysis","volume":"30","author":"Khan","year":"2018","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.envpol.2020.114399_bib19","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1186\/s13104-015-1265-y","article-title":"Fatal non-thrombotic pulmonary embolization in a patient with undiagnosed factitious disorder","volume":"8","author":"Kwon","year":"2015","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.envpol.2020.114399_bib20","first-page":"479","article-title":"Achromobacter xylosoxidans bacteremia in patients with cancer","volume":"2","author":"Kynaston","year":"2015","journal-title":"Open Forum Infect. Di."},{"key":"10.1016\/j.envpol.2020.114399_bib21","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/nbt.2676","article-title":"Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences","volume":"31","author":"Langille","year":"2013","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.envpol.2020.114399_bib22","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1136\/gutjnl-2016-312132","article-title":"Antibiotic-induced gut microbiota disruption during human endotoxemia: a randomised controlled study","volume":"66","author":"Lankelma","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.envpol.2020.114399_bib23","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.envint.2017.09.013","article-title":"Integrating human and environmental health in antibiotic risk assessment: a critical analysis of protection goals, species sensitivity and antimicrobial resistance","volume":"109","author":"Le Page","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2020.114399_bib24","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nature12447","article-title":"Bacterial colonization factors control specificity and stability of the gut microbiota","volume":"501","author":"Lee","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.envpol.2020.114399_bib25","first-page":"621","article-title":"Hospital acquired pneumonia due to Achromobacter spp. in a geriatric ward in China: clinical characteristic, genome variability, biofilm production, antibiotic resistance and integron in isolated strains","volume":"7","author":"Liu","year":"2016","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2020.114399_bib26","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: a new phylogenetic method for comparing microbial communities","volume":"71","author":"Lozupone","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envpol.2020.114399_bib27","first-page":"456","article-title":"Fecal microbiota transplantation","volume":"58","author":"Lubbert","year":"2017","journal-title":"Internist"},{"key":"10.1016\/j.envpol.2020.114399_bib28","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1080\/23744235.2016.1177199","article-title":"Fecal microbiota transplantation for the intestinal decolonization of extensively antimicrobial-resistant opportunistic pathogens: a review","volume":"48","author":"Manges","year":"2016","journal-title":"Inf. Disp."},{"key":"10.1016\/j.envpol.2020.114399_bib29","doi-asserted-by":"crossref","first-page":"S124","DOI":"10.1097\/MCG.0000000000000711","article-title":"An advanced in\u00a0vitro technology platform to study the mechanism of action of prebiotics and probiotics in the gastrointestinal tract","volume":"50","author":"Marzorati","year":"2016","journal-title":"J.\u00a0Clin. Gastroenterol."},{"key":"10.1016\/j.envpol.2020.114399_bib30","doi-asserted-by":"crossref","first-page":"1600150","DOI":"10.1002\/mnfr.201600150","article-title":"High-fiber and high-protein diets shape different gut microbial communities, which ecologically behave similarly under stress conditions, as shown in a gastrointestinal simulator","volume":"61","author":"Marzorati","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.envpol.2020.114399_bib31","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1093\/cid\/ciy149","article-title":"Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the infectious diseases society of America (IDSA) and society for healthcare epidemiology of America (SHEA)","volume":"66","author":"McDonald","year":"2018","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.envpol.2020.114399_bib32","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S1473-3099(13)70190-7","article-title":"Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases","volume":"13","author":"Munoz-Price","year":"2013","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.envpol.2020.114399_bib33","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1136\/gutjnl-2019-319407","article-title":"Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific association of gastroenterology (APAGE) and Asia-Pacific society for digestive endoscopy (APSDE)","volume":"69","author":"Ng","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.envpol.2020.114399_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113067","article-title":"Freshwater environments as reservoirs of antibiotic resistant bacteria and their role in the dissemination of antibiotic resistance genes","volume":"254","author":"Nnadozie","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2020.114399_bib35","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.cmet.2016.06.016","article-title":"Effects of gut microbiota manipulation by antibiotics on host metabolism in obese humans: a randomized double-blind placebo-controlled trial","volume":"24","author":"Reijnders","year":"2016","journal-title":"Cell Metabol."},{"key":"10.1016\/j.envpol.2020.114399_bib36","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4322\/acr.2017.029","article-title":"Native-valve endocarditis caused by Achromobacter xylosoxidans: a case report and review of literature","volume":"7","author":"Rodrigues","year":"2017","journal-title":"Autops. Case Rep."},{"key":"10.1016\/j.envpol.2020.114399_bib37","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1093\/infdis\/jiv440","article-title":"Klebsiella pneumoniae FimK promotes virulence in murine pneumonia","volume":"213","author":"Rosen","year":"2016","journal-title":"J.\u00a0Infect. Dis."},{"key":"10.1016\/j.envpol.2020.114399_bib38","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol."},{"key":"10.1016\/j.envpol.2020.114399_bib39","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.schres.2018.01.002","article-title":"Analysis of gut microbiota diversity and auxiliary diagnosis as a biomarker in patients with schizophrenia: a cross-sectional study","volume":"197","author":"Shen","year":"2018","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.envpol.2020.114399_bib40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.envpol.2018.01.052","article-title":"Performance evaluation of Bacteroidales genetic markers for human and animal microbial source tracking in tropical agricultural watersheds","volume":"236","author":"Somnark","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2020.114399_bib41","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1038\/nrmicro2989","article-title":"\u2019Blooming\u2019 in the gut: how dysbiosis might contribute to pathogen evolution","volume":"11","author":"Stecher","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envpol.2020.114399_bib42","doi-asserted-by":"crossref","first-page":"113108","DOI":"10.1016\/j.envpol.2019.113108","article-title":"Next-generation sequencing reveals fecal contamination and potentially pathogenic bacteria in a major inflow river of Taihu Lake","volume":"254","author":"Vadde","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2020.114399_bib43","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/ismej.2012.158","article-title":"Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in\u00a0vitro gut model","volume":"7","author":"Van den Abbeele","year":"2013","journal-title":"ISME J."},{"key":"10.1016\/j.envpol.2020.114399_bib44","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1751-7915.2011.00308.x","article-title":"Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by Lactobacilli","volume":"5","author":"Van den Abbeele","year":"2012","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.envpol.2020.114399_bib45","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jhep.2013.11.034","article-title":"Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity","volume":"60","author":"Vrieze","year":"2014","journal-title":"J.\u00a0Hepatol."},{"key":"10.1016\/j.envpol.2020.114399_bib46","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1007\/s11274-018-2449-0","article-title":"Molecular profiling of mucosal tissue associated microbiota in patients manifesting acute exacerbations and remission stage of ulcerative colitis","volume":"34","author":"Walujkar","year":"2018","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.envpol.2020.114399_bib47","doi-asserted-by":"crossref","first-page":"121129","DOI":"10.1016\/j.jhazmat.2019.121129","article-title":"Occurrence and distribution of clinical and veterinary antibiotics in the faeces of a Chinese population","volume":"383","author":"Wang","year":"2020","journal-title":"J.\u00a0Hazard Mater."},{"key":"10.1016\/j.envpol.2020.114399_bib48","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Wang","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envpol.2020.114399_bib49","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jhazmat.2018.05.011","article-title":"Influence of gastrointestinal tract on metabolism of bisphenol A as determined by in\u00a0vitro simulated system","volume":"355","author":"Wang","year":"2018","journal-title":"J.\u00a0Hazard Mater."},{"key":"10.1016\/j.envpol.2020.114399_bib50","doi-asserted-by":"crossref","first-page":"7189","DOI":"10.1021\/acs.est.6b01533","article-title":"Arsenic metabolism and toxicity influenced by ferric iron in simulated gastrointestinal tract and the roles of gut microbiota","volume":"50","author":"Yu","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2020.114399_bib51","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s13238-018-0541-8","article-title":"Microbiota transplantation: concept, methodology and strategy for its modernization","volume":"9","author":"Zhang","year":"2018","journal-title":"Protein Cell"},{"key":"10.1016\/j.envpol.2020.114399_bib52","doi-asserted-by":"crossref","DOI":"10.1007\/s13238-019-00684-8","article-title":"Washed microbiota transplantation vs. manual fecal microbiota transplantation: clinical findings, animal studies and in\u00a0vitro screening","author":"Zhang","year":"2020","journal-title":"Protein Cell"},{"key":"10.1016\/j.envpol.2020.114399_bib53","doi-asserted-by":"crossref","first-page":"6115","DOI":"10.1128\/AAC.01127-16","article-title":"High prevalence of hypervirulent Klebsiella pneumoniae infection in China: geographic distribution, clinical characteristics, and antimicrobial resistance","volume":"60","author":"Zhang","year":"2016","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749120300130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749120300130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:06:33Z","timestamp":1777539993000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749120300130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":53,"alternative-id":["S0269749120300130"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2020.114399","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vancomycin exposure caused opportunistic pathogens bloom in intestinal microbiome by simulator of the human intestinal microbial ecosystem (SHIME)","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2020.114399","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114399"}}