{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:55:39Z","timestamp":1789707339560,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.envpol.2020.115578","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T08:31:23Z","timestamp":1598949083000},"page":"115578","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Response mechanisms of domoic acid in Pseudo-nitzschia multiseries under copper stress"],"prefix":"10.1016","volume":"272","author":[{"given":"Yu","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadi","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoguang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2020.115578_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.hal.2018.06.001","article-title":"Pseudo-nitzschia, Nitzschia, and domoic acid: new research since 2011","author":"Bates","year":"2018","journal-title":"Harmful Algae"},{"key":"10.1016\/j.envpol.2020.115578_bib2","series-title":"Microalgae in Health and Disease Prevention","first-page":"263","article-title":"Microalgae and toxins","author":"Caruana","year":"2018"},{"issue":"1","key":"10.1016\/j.envpol.2020.115578_bib4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1021\/es060746i","article-title":"Combined exposure to hydrogen peroxide and light selective effects on cyanobacteria, green algae, and diatoms","volume":"41","author":"Dr\u00e1bkov\u00e1","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2020.115578_bib6","series-title":"Oxygen and Living Processes","first-page":"250","article-title":"Superoxide radical and superoxide dismutases","author":"Fridovich","year":"1981"},{"key":"10.1016\/j.envpol.2020.115578_bib7","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.marenvres.2012.10.005","article-title":"Control of domoic acid toxin expression in Pseudo-nitzschia multiseries by copper and silica: relevance to mussel aquaculture in New England (USA)","volume":"83","author":"Fuentes","year":"2013","journal-title":"Mar. Environ. Res."},{"issue":"1","key":"10.1016\/j.envpol.2020.115578_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12867-019-0124-0","article-title":"Transcriptomic responses to grazing reveal the metabolic pathway leading to the biosynthesis of domoic acid and highlight different defense strategies in diatoms","volume":"20","author":"Har\u00f0ard\u00f3ttir","year":"2019","journal-title":"BMC Mol. Biol."},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib9","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1529-8817.2008.00471.x","article-title":"The role OF reactive oxygen species IN copper toxicity to two freshwater green algae","volume":"44","author":"Knauert","year":"2008","journal-title":"J.\u00a0Phycol."},{"issue":"6","key":"10.1016\/j.envpol.2020.115578_bib10","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1021\/es950331p","article-title":"Export of cadmium and phytochelatin by the marine diatom Thalassiosira weissflogii","volume":"30","author":"Lee","year":"1996","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib11","doi-asserted-by":"crossref","first-page":"168","DOI":"10.2216\/11-37.1","article-title":"Pseudo-nitzschia (Bacillariophyceae) species, domoic acid and amnesic shellfish poisoning: revisiting previous paradigms","volume":"51","author":"Lelong","year":"2012","journal-title":"Phycologia"},{"key":"10.1016\/j.envpol.2020.115578_bib12","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.aquatox.2012.03.010","article-title":"Impact of copper exposure on Pseudo-nitzschia spp. physiology and domoic acid production","author":"Lelong","year":"2012","journal-title":"Aquat. Toxicol."},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib13","doi-asserted-by":"crossref","first-page":"613","DOI":"10.4319\/lo.2013.58.2.0613","article-title":"Iron and copper limitations differently affect growth rates and photosynthetic and physiological parameters of the marine diatom Pseudo-nitzschia delicatissima","volume":"58","author":"Lelong","year":"2013","journal-title":"Limnol. Oceanogr."},{"issue":"11","key":"10.1016\/j.envpol.2020.115578_bib14","doi-asserted-by":"crossref","first-page":"6545","DOI":"10.1128\/AEM.71.11.6545-6553.2005","article-title":"Isolation and characterization of a novel antialgal allelochemical from Phragmites communis","volume":"71","author":"Li","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"issue":"1","key":"10.1016\/j.envpol.2020.115578_bib15","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-18651-w","article-title":"Six domoic acid related compounds from the red alga, Chondria armata , and domoic acid biosynthesis by the diatom, Pseudo-nitzschia multiseries","volume":"8","author":"Maeno","year":"2018","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib16","doi-asserted-by":"crossref","first-page":"515","DOI":"10.4319\/lo.2002.47.2.0515","article-title":"The effect of Fe and Cu on growth and domoic acid production by Pseudo-nitzschia multiseries and Pseudo-nitzschia australis","volume":"47","author":"Maldonado","year":"2002","journal-title":"Limnol. Oceanogr."},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1046\/j.1469-8137.1999.00447.x","article-title":"Heavy-metal-induced proline accumulation and its role in ameliorating metal toxicity in chlorella vulgaris","volume":"143","author":"Mehta","year":"1999","journal-title":"New Phytol."},{"issue":"3","key":"10.1016\/j.envpol.2020.115578_bib18","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1007\/s10811-014-0426-z","article-title":"Toxicological effects of metal-EDTA\/NTA complex formation in a synthetic medium on the macroalga Gracilaria domingensis","volume":"27","author":"Mendes","year":"2015","journal-title":"J.\u00a0Appl. Phycol."},{"issue":"4","key":"10.1016\/j.envpol.2020.115578_bib19","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/17429145.2010.539708","article-title":"Effect of exogenous arginine on alleviation of oxidative damage in tomato plant underwater stress","volume":"6","author":"Nasibi","year":"2011","journal-title":"J.\u00a0Plant Interact."},{"issue":"21","key":"10.1016\/j.envpol.2020.115578_bib21","doi-asserted-by":"crossref","first-page":"21523","DOI":"10.1007\/s11356-016-7418-2","article-title":"Using H2O2 treatments for the degradation of cyanobacteria and microcystins in a shallow hypertrophic reservoir","volume":"23","author":"Papadimitriou","year":"2016","journal-title":"Environ. Sci. Pollut. Control Ser."},{"issue":"6","key":"10.1016\/j.envpol.2020.115578_bib22","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1111\/j.0022-3646.2003.02-193.x","article-title":"Heavy metal\u2013induced oxidative stress in algae","volume":"39","author":"Pinto","year":"2003","journal-title":"J.\u00a0Phycol."},{"issue":"1","key":"10.1016\/j.envpol.2020.115578_bib23","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0304-4203(01)00053-6","article-title":"Domoic acid binds iron and copper: a possible role for the toxin produced by the marine diatom Pseudo-nitzschia","volume":"76","author":"Rue","year":"2001","journal-title":"Mar. Chem."},{"issue":"11","key":"10.1016\/j.envpol.2020.115578_bib24","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1105\/tpc.004853","article-title":"Molecular mechanisms of proline-mediated tolerance to toxic heavy metals in transgenic microalgae","volume":"14","author":"Siripornadulsil","year":"2002","journal-title":"Plant Cell"},{"issue":"2","key":"10.1016\/j.envpol.2020.115578_bib25","doi-asserted-by":"crossref","first-page":"516","DOI":"10.4319\/lo.2005.50.2.0516","article-title":"Response of nonprotein thiols to copper stress and extracellular release of glutathione in the diatom Thalassiosira weissflogii","volume":"50","author":"Tang","year":"2005","journal-title":"Limnol. Oceanogr."},{"issue":"3","key":"10.1016\/j.envpol.2020.115578_bib26","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s00425-004-1237-2","article-title":"Relationship between copper- and zinc-induced oxidative stress and proline accumulation inscenedesmussp","volume":"219","author":"Tripathi","year":"2004","journal-title":"Planta"},{"issue":"6","key":"10.1016\/j.envpol.2020.115578_bib27","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.4319\/lo.2005.50.6.1908","article-title":"Domoic acid: the synergy of iron, copper, and the toxicity of diatoms","volume":"50","author":"Wells","year":"2005","journal-title":"Limnol. Oceanogr."},{"issue":"3","key":"10.1016\/j.envpol.2020.115578_bib28","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF02277422","article-title":"Catalases in plants","volume":"1","author":"Willekens","year":"1995","journal-title":"Mol. Breed."},{"issue":"1","key":"10.1016\/j.envpol.2020.115578_bib29","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1046\/j.1529-8817.1998.340113.x","article-title":"Role OF proline accumulation IN response to toxic copper IN chlorella SP. (CHLOROPHYCEAE) cells","volume":"34","author":"Wu","year":"1998","journal-title":"J.\u00a0Phycol."},{"key":"10.1016\/j.envpol.2020.115578_bib30","series-title":"Effect of Organic Ligands on Distribution of Copper in Microcystis Aeruginosa and the Content of Pigment","author":"Xiaorong","year":"2007"},{"key":"10.1016\/j.envpol.2020.115578_bib31","series-title":"Morphological Study and Toxic Analysis for Two Pseudo-nitzschia Species Isolated from Daya Bay","author":"Xuyin","year":"2007"}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749120362667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749120362667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T21:50:57Z","timestamp":1759441857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749120362667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":28,"alternative-id":["S0269749120362667"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2020.115578","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Response mechanisms of domoic acid in Pseudo-nitzschia multiseries under copper stress","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2020.115578","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115578"}}