{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:42:32Z","timestamp":1790707352249,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,15]],"date-time":"2022-02-15T00:00:00Z","timestamp":1644883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.envpol.2022.118994","type":"journal-article","created":{"date-parts":[[2022,2,12]],"date-time":"2022-02-12T02:53:12Z","timestamp":1644634392000},"page":"118994","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"special_numbering":"C","title":["Semen quality and sperm DNA methylation in relation to long-term exposure to air pollution in fertile men: A cross-sectional study"],"prefix":"10.1016","volume":"300","author":[{"given":"Yuting","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuqin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peihao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2572-3454","authenticated-orcid":false,"given":"Jinhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiumei","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-5080","authenticated-orcid":false,"given":"Minjian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3689-9188","authenticated-orcid":false,"given":"Chuncheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinru","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9110-9973","authenticated-orcid":false,"given":"Wei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yankai","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2022.118994_bib1","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/j.fertnstert.2015.08.019","article-title":"Aberrant sperm DNA methylation predicts male fertility status and embryo quality","volume":"104","author":"Aston","year":"2015","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ajhg.2013.11.017","article-title":"Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella","volume":"94","author":"Ben Khelifa","year":"2014","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.envpol.2022.118994_bib3","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.fertnstert.2013.10.022","article-title":"Semen quality and time to pregnancy: the longitudinal investigation of fertility and the environment study","volume":"101","author":"Buck Louis","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxlet.2016.12.004","article-title":"Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity","volume":"266","author":"Cao","year":"2017","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2022.118994_bib5","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1186\/s12894-020-00710-6","article-title":"Ambient sulfur dioxide could have an impact on testicular volume from a observational study on a population of infertile male","volume":"20","author":"Chen","year":"2020","journal-title":"BMC Urol."},{"key":"10.1016\/j.envpol.2022.118994_bib6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1146\/annurev-biochem-103019-102815","article-title":"Role of mammalian DNA methyltransferases in development","volume":"89","author":"Chen","year":"2020","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.envpol.2022.118994_bib7","doi-asserted-by":"crossref","first-page":"853","DOI":"10.4161\/epi.6.7.16461","article-title":"Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress","volume":"6","author":"Chia","year":"2011","journal-title":"Epigenetics"},{"key":"10.1016\/j.envpol.2022.118994_bib8","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/humupd\/dmp048","article-title":"World Health Organization reference values for human semen characteristics","volume":"16","author":"Cooper","year":"2010","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.envpol.2022.118994_bib9","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.envint.2013.07.007","article-title":"Influence of ambient air pollution on global DNA methylation in healthy adults: a seasonal follow-up","volume":"59","author":"De Prins","year":"2013","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2022.118994_bib10","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/humrep\/dev283","article-title":"Promoter targeted bisulfite sequencing reveals DNA methylation profiles associated with low sperm motility in asthenozoospermia","volume":"31","author":"Du","year":"2016","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.envpol.2022.118994_bib11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.rbr.2015.07.002","article-title":"Ozone decreases sperm quality in systemic lupus erythematosus patients","volume":"56","author":"Farhat","year":"2016","journal-title":"Rev. Bras. Reumatol. Engl. Ed."},{"key":"10.1016\/j.envpol.2022.118994_bib12","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/andr.12198","article-title":"Chronic exposures and male fertility: the impacts of environment, diet, and drug use on spermatogenesis","volume":"4","author":"Gabrielsen","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.envpol.2022.118994_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.toxlet.2019.08.007","article-title":"Pubertal exposure to low doses of zearalenone disrupting spermatogenesis through ER\u03b1 related genetic and epigenetic pathways","volume":"315","author":"Gao","year":"2019","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2022.118994_bib14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13148-020-00995-2","article-title":"Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility","volume":"13","author":"Garrido","year":"2021","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.envpol.2022.118994_bib15","doi-asserted-by":"crossref","first-page":"110319","DOI":"10.1016\/j.ecoenv.2020.110319","article-title":"Effects of particulate matter exposure on semen quality: a retrospective cohort study","volume":"193","author":"Guan","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2022.118994_bib16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.fertnstert.2016.09.035","article-title":"Decline in semen quality among 30,636 young Chinese men from 2001 to 2015","volume":"107","author":"Huang","year":"2017","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib17","doi-asserted-by":"crossref","first-page":"e313","DOI":"10.1016\/S2542-5196(18)30141-4","article-title":"Health impact of China's Air Pollution Prevention and Control Action Plan: an analysis of national air quality monitoring and mortality data","volume":"2","author":"Huang","year":"2018","journal-title":"Lanc. Planet Health"},{"key":"10.1016\/j.envpol.2022.118994_bib18","doi-asserted-by":"crossref","first-page":"5957","DOI":"10.1021\/acs.est.8b06942","article-title":"Association of exposure to ambient fine particulate matter constituents with semen quality among men attending a fertility center in China","volume":"53","author":"Huang","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2022.118994_bib19","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/andr.12231","article-title":"Teratozoospermia and asthenozoospermia are associated with specific epigenetic signatures","volume":"4","author":"Jenkins","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.envpol.2022.118994_bib20","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.fertnstert.2015.09.013","article-title":"Decreased fecundity and sperm DNA methylation patterns","volume":"105","author":"Jenkins","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib21","doi-asserted-by":"crossref","first-page":"113331","DOI":"10.1016\/j.envpol.2019.113331","article-title":"PM2.5-induced extensive DNA methylation changes in the heart of zebrafish embryos and the protective effect of folic acid","volume":"255","author":"Jiang","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2022.118994_bib22","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.urology.2017.06.045","article-title":"Impacts of abstinence time on semen parameters in a large population-based cohort of subfertile men","volume":"108","author":"Keihani","year":"2017","journal-title":"Urology"},{"key":"10.1016\/j.envpol.2022.118994_bib23","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.fertnstert.2016.08.022","article-title":"Outdoor air pollution and sperm quality","volume":"106","author":"Lafuente","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib24","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/oemed-2017-104529","article-title":"Exposure to ambient fine particulate matter and semen quality in Taiwan","volume":"75","author":"Lao","year":"2018","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.envpol.2022.118994_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2013.02.010","article-title":"Seasonal variations of human sperm cells among 6455 semen samples: a plausible explanation of a seasonal birth pattern","volume":"208","author":"Levitas","year":"2013","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.envpol.2022.118994_bib26","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3389\/fimmu.2019.00210","article-title":"TET enzymes and 5hmC in adaptive and innate immune systems","volume":"10","author":"Lio","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.envpol.2022.118994_bib27","doi-asserted-by":"crossref","first-page":"115631","DOI":"10.1016\/j.envpol.2020.115631","article-title":"Spatial distribution prediction of soil as in a large-scale arsenic slag contaminated site based on an integrated model and multi-source environmental data","volume":"267","author":"Liu","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2022.118994_bib28","doi-asserted-by":"crossref","first-page":"12806","DOI":"10.1021\/acs.est.7b03289","article-title":"Inverse association between ambient sulfur dioxide exposure and semen quality in Wuhan, China","volume":"51","author":"Liu","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2022.118994_bib29","first-page":"916","article-title":"Overview on the spatial-temporal characteristics of the ozone formation regime in China","volume":"21","author":"Lu","year":"2019","journal-title":"Environ. Sci. Proc. Imp."},{"key":"10.1016\/j.envpol.2022.118994_bib30","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/07420528.2017.1280046","article-title":"Environmental factors contributed to circannual rhythm of semen quality","volume":"34","author":"Mao","year":"2017","journal-title":"Chronobiol. Int."},{"key":"10.1016\/j.envpol.2022.118994_bib31","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1146\/annurev-publhealth-040617-014629","article-title":"Environmental influences on the epigenome: exposure- associated DNA methylation in human populations","volume":"39","author":"Martin","year":"2018","journal-title":"Annu. Rev. Publ. Health"},{"key":"10.1016\/j.envpol.2022.118994_bib32","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/andr.12001","article-title":"Sperm global DNA methylation level: association with semen parameters and genome integrity","volume":"3","author":"Montjean","year":"2015","journal-title":"Andrology"},{"key":"10.1016\/j.envpol.2022.118994_bib33","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1556\/004.2015.035","article-title":"Correlation between bull fertility and sperm cell velocity parameters generated by computer-assisted semen analysis","volume":"63","author":"Nagy","year":"2015","journal-title":"Acta Vet. Hung."},{"key":"10.1016\/j.envpol.2022.118994_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150528","article-title":"Pitfalls of DNA quantification using DNA-binding fluorescent dyes and suggested solutions","volume":"11","author":"Nakayama","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2022.118994_bib35","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1093\/humrep\/dew096","article-title":"TET enzymes are successively expressed during human spermatogenesis and their expression level is pivotal for male fertility","volume":"31","author":"Ni","year":"2016","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.envpol.2022.118994_bib36","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/humrep\/dex341","article-title":"Time-varying cycle average and daily variation in ambient air pollution and fecundability","volume":"33","author":"Nobles","year":"2018","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.envpol.2022.118994_bib37","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.envres.2018.02.004","article-title":"Ambient air pollution and semen quality","volume":"163","author":"Nobles","year":"2018","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mrrev.2011.04.002","article-title":"Epigenetics, spermatogenesis and male infertility","volume":"727","author":"Rajender","year":"2011","journal-title":"Mutat. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib39","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1756-8935-7-19","article-title":"Dynamic changes in DNA modification states during late gestation male germ line development in the rat","volume":"7","author":"Rose","year":"2014","journal-title":"Epigenet. Chromatin"},{"key":"10.1016\/j.envpol.2022.118994_bib40","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1080\/15592294.2015.1050174","article-title":"Effects of particulate matter exposure on blood 5-hydroxymethylation: results from the Beijing truck driver air pollution study","volume":"10","author":"Sanchez-Guerra","year":"2015","journal-title":"Epigenetics"},{"key":"10.1016\/j.envpol.2022.118994_bib41","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.fertnstert.2020.04.045","article-title":"Differential DNA methylation pattern and sperm quality in men with varicocele","volume":"114","author":"Santana","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.envpol.2022.118994_bib42","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.envres.2016.05.053","article-title":"Sperm quality and environment: a retrospective, cohort study in a Northern province of Italy","volume":"150","author":"Santi","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib43","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.eururo.2016.04.010","article-title":"Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 World health organization laboratory methods for the examination of human semen","volume":"70","author":"Sharma","year":"2016","journal-title":"Eur. Urol."},{"key":"10.1016\/j.envpol.2022.118994_bib44","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.ecoenv.2019.02.086","article-title":"A review of the possible associations between ambient PM2.5 exposures and the development of Alzheimer's disease","volume":"174","author":"Shou","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2022.118994_bib45","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.envres.2018.07.004","article-title":"Preconception seminal plasma concentrations of endocrine disrupting chemicals in relation to semen quality parameters among male partners planning for pregnancy","volume":"167","author":"Smarr","year":"2018","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib46","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1289\/ehp.8232","article-title":"Exposure to environmental ozone alters semen quality","volume":"114","author":"Sokol","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2022.118994_bib47","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s40572-017-0162-z","article-title":"Statistical approaches to address multi-pollutant mixtures and multiple exposures: the state of the science","volume":"4","author":"Stafoggia","year":"2017","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.envpol.2022.118994_bib48","doi-asserted-by":"crossref","first-page":"109894","DOI":"10.1016\/j.envres.2020.109894","article-title":"Identifying critical exposure windows for ambient air pollution and semen quality in Chinese men","volume":"189","author":"Sun","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib49","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/s13148-018-0568-y","article-title":"Idiopathic male infertility is strongly associated with aberrant DNA methylation of imprinted loci in sperm: a case-control study","volume":"10","author":"Tang","year":"2018","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.envpol.2022.118994_bib50","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.ajhg.2017.04.012","article-title":"Biallelic mutations in CFAP43 and CFAP44 cause male infertility with multiple morphological abnormalities of the sperm flagella","volume":"100","author":"Tang","year":"2017","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.envpol.2022.118994_bib51","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s13148-020-00908-3","article-title":"AHRR cg05575921 methylation in relation to smoking and PM(2.5) exposure among Taiwanese men and women","volume":"12","author":"Tantoh","year":"2020","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.envpol.2022.118994_bib52","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.rbmo.2016.08.022","article-title":"DNA methyltransferases exhibit dynamic expression during spermatogenesis","volume":"33","author":"Uysal","year":"2016","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.envpol.2022.118994_bib53","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/nrurol.2016.261","article-title":"Semen quality in the 21(st) century","volume":"14","author":"Virtanen","year":"2017","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.envpol.2022.118994_bib54","doi-asserted-by":"crossref","first-page":"128436","DOI":"10.1016\/j.chemosphere.2020.128436","article-title":"Effects of PM(2.5) exposure on reproductive system and its mechanisms","volume":"264","author":"Wang","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2022.118994_bib55","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12940-020-00595-w","article-title":"The association between ambient temperature and sperm quality in Wuhan, China","volume":"19","author":"Wang","year":"2020","journal-title":"Environ. Health"},{"key":"10.1016\/j.envpol.2022.118994_bib56","doi-asserted-by":"crossref","first-page":"116514","DOI":"10.1016\/j.envpol.2021.116514","article-title":"Association of air pollution and greenness with carotid plaque: a prospective cohort study in China","volume":"273","author":"Xie","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2022.118994_bib57","first-page":"104","article-title":"[Long-term exposure to PM2.5 from automobile exhaust results in reproductive dysfunction in male rats]","volume":"22","author":"Yan","year":"2016","journal-title":"Zhonghua Nan ke Xue"},{"key":"10.1016\/j.envpol.2022.118994_bib58","doi-asserted-by":"crossref","first-page":"111085","DOI":"10.1016\/j.envres.2021.111085","article-title":"Semen quality and windows of susceptibility: a case study during COVID-19 outbreak in China","volume":"197","author":"Yang","year":"2021","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2022.118994_bib59","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1073\/pnas.0705896105","article-title":"Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban\/industrial location","volume":"105","author":"Yauk","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.envpol.2022.118994_bib60","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.envint.2019.03.052","article-title":"Temporal and spatial variation of greenhouse gas emissions from a limited-controlled landfill site","volume":"127","author":"Zhang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2022.118994_bib61","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4103\/aja.aja_116_18","article-title":"Ambient ozone pollution is associated with decreased semen quality: longitudinal analysis of 8945 semen samples from 2015 to 2018 and during pollution-control period in Beijing, China","volume":"21","author":"Zhang","year":"2019","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.envpol.2022.118994_bib62","doi-asserted-by":"crossref","first-page":"7528901","DOI":"10.1155\/2020\/7528901","article-title":"Impacts of outdoor air pollution on human semen quality: a meta-analysis and systematic review","volume":"2020","author":"Zhang","year":"2020","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.envpol.2022.118994_bib63","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.envint.2018.11.076","article-title":"Association between exposure to a mixture of phenols, pesticides, and phthalates and obesity: comparison of three statistical models","volume":"123","author":"Zhang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2022.118994_bib64","doi-asserted-by":"crossref","first-page":"124308","DOI":"10.1016\/j.jhazmat.2020.124308","article-title":"Sperm mtDNA copy number, telomere length, and seminal spermatogenic cells in relation to ambient air pollution: results of a cross-sectional study in Jing-Jin-Ji region of China","volume":"406","author":"Zhou","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2022.118994_bib65","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envpol.2013.12.030","article-title":"Air pollution and decreased semen quality: a comparative study of Chongqing urban and rural areas","volume":"187","author":"Zhou","year":"2014","journal-title":"Environ. Pollut."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749122002081?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749122002081?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T22:29:13Z","timestamp":1759444153000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749122002081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":65,"alternative-id":["S0269749122002081"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2022.118994","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Semen quality and sperm DNA methylation in relation to long-term exposure to air pollution in fertile men: A cross-sectional study","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2022.118994","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"118994"}}