{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T10:14:46Z","timestamp":1785838486146,"version":"3.56.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.envpol.2023.121722","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T11:35:53Z","timestamp":1682422553000},"page":"121722","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Trajectory of neutrophilic responses in a mouse model of pollutant-aggravated allergic asthma"],"prefix":"10.1016","volume":"329","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2101-1011","authenticated-orcid":false,"given":"Joyceline","family":"De Volder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelies","family":"Bontinck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrien","family":"De Grove","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2168-0781","authenticated-orcid":false,"given":"Iris","family":"Dirven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2186-6968","authenticated-orcid":false,"given":"Valerie","family":"Haelterman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3149-9444","authenticated-orcid":false,"given":"Guy","family":"Joos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7021-8505","authenticated-orcid":false,"given":"Guy","family":"Brusselle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3037-6928","authenticated-orcid":false,"given":"Tania","family":"Maes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.envpol.2023.121722_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/MCP.0000000000000644","article-title":"Asthma and air pollution: recent insights in pathogenesis and clinical implications","volume":"26","author":"Bontinck","year":"2020","journal-title":"Curr. Opin. Pulm. Med."},{"issue":"4","key":"10.1016\/j.envpol.2023.121722_bib2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000381058","article-title":"Long-term exposure to HDM leads to suppression of allergic airway disease despite persistent lung inflammation","volume":"166","author":"Bracken","year":"2015","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib4","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.3389\/fimmu.2020.01259","article-title":"Multiple roles for chemokines in neutrophil biology","volume":"11","author":"Capucetti","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/thoraxjnl-2015-207399","article-title":"Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study","volume":"71","author":"Carlsten","year":"2016","journal-title":"Thorax"},{"issue":"9","key":"10.1016\/j.envpol.2023.121722_bib8","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/j.1365-2222.2005.02328.x","article-title":"Environmental risk factors and allergic bronchial asthma","volume":"35","author":"D'Amato","year":"2005","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.envpol.2023.121722_bib9","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1016\/j.celrep.2018.02.062","article-title":"Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing","volume":"22","author":"Sullivan","year":"2018","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.envpol.2023.121722_bib10","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/S0091-6749(99)70011-4","article-title":"Nasal challenge with diesel exhaust particles can induce sensitization to a neoallergen in the human mucosa","volume":"104","author":"Diaz-Sanchez","year":"1999","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.immuni.2010.07.012","article-title":"The mysterious ways of the chemokine CXCL5","volume":"33","year":"2010","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.envpol.2023.121722_bib12","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/mi.2014.9","article-title":"TRIAL mediates the resolution of allergic airway inflammation induced by chronic allergen inhalation","volume":"7","author":"Faustino","year":"2014","journal-title":"Mucosal Immunol."},{"issue":"24","key":"10.1016\/j.envpol.2023.121722_bib13","doi-asserted-by":"crossref","first-page":"4930","DOI":"10.1182\/blood-2013-02-486217","article-title":"Mast cell and macrophage chemokines CXCL1\/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation","volume":"121","author":"De Filippo","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.envpol.2023.121722_bib14","doi-asserted-by":"crossref","first-page":"651","DOI":"10.3390\/ijms21020651","article-title":"Potent and broad but not unselective cleavage of cytokines and chemokines by human neutrophil elastase and proteinase 3","volume":"21","author":"Fu","year":"2020","journal-title":"International Archives of Molecular Sciences"},{"issue":"1","key":"10.1016\/j.envpol.2023.121722_bib16","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.jaci.2016.03.044","article-title":"Dysregulation of type 2 innate lymphoid cells and Th2 cells impairs pollutant-induced allergic airway responses","volume":"139","author":"De Grove","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"issue":"12","key":"10.1016\/j.envpol.2023.121722_bib17","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1111\/cea.13261","article-title":"IL-33 signalling contributes to pollutant-induced allergic airway inflammation","volume":"48","author":"De Grove","year":"2018","journal-title":"Clin. Exp. Allergy"},{"issue":"7","key":"10.1016\/j.envpol.2023.121722_bib18","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1111\/cea.13178","article-title":"Insights in particulate matter - induced allergic airway inflammation: focus on the epithelium","volume":"48","author":"De Grove","year":"2018","journal-title":"Clin. Exp. Allergy"},{"issue":"12","key":"10.1016\/j.envpol.2023.121722_bib19","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s00011-009-0054-2","article-title":"Mouse models of asthma: a comparison between C57BL\/6 and BALB\/c strains regarding bronchial responsiveness, inflammation, and cytokine production","volume":"58","author":"Gueders","year":"2009","journal-title":"Inflamm. Res."},{"issue":"1","key":"10.1016\/j.envpol.2023.121722_bib20","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1165\/rcmb.2015-0044OC","article-title":"Facilitation of allergic sensitization and allergic airway inflammation by pollen-induced innate neutrophil recruitment","volume":"54","author":"Hosoki","year":"2016","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"6","key":"10.1016\/j.envpol.2023.121722_bib22","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1016\/j.ajpath.2011.08.008","article-title":"DEP exacerbate asthma-like inflammation by increasing CXC chemokines","volume":"179","author":"Kim","year":"2011","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.envpol.2023.121722_bib23","doi-asserted-by":"crossref","unstructured":"Lachowicz-Scroggins, Marrah, Dunican, Eleanor, Charbit, Annabelle et al., 2019. Extracellular DNA, neutrophil extracellular traps and inflammasome activation in severe asthma. Am. J. Respir. Crit. Care Med. 199 (9), 1076\u20131085. doi:10.1164\/rccm.201810-1869OC.","DOI":"10.1164\/rccm.201810-1869OC"},{"key":"10.1016\/j.envpol.2023.121722_bib24","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1038\/nm.2737","article-title":"The airway epithelium in asthma","volume":"18","author":"Lambrecht","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.envpol.2023.121722_bib25","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jaci.2006.02.034","article-title":"The course of allergen-induced leukocyte infiltration in human and experimental asthma","volume":"118","author":"Lommatzsch","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib3","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1172\/JCI124612","article-title":"Environmental exposures and mechanisms in allergy and asthma development","volume":"129","author":"Murrison","year":"2019","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.envpol.2023.121722_bib26","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1046\/j.1365-2222.2003.01609.x","article-title":"Expression of the neutrophil-activating CXC chemokine ENA-78\/CXCL5 by human eosinophils","volume":"33","author":"Persson","year":"2003","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.envpol.2023.121722_bib27","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/cea.12859","article-title":"Neutrophil autophagy and extracellular DNA traps contribute to airway inflammation in severe asthma","volume":"47","author":"Pham","year":"2017","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.envpol.2023.121722_bib28","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4049\/jimmunol.0902564","article-title":"Diesel exhaust particles stimulate adaptive immunity by acting on pulmonary dendritic cells","volume":"184","author":"Provoost","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib29","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.coi.2018.05.006","article-title":"Role of neutrophils in allergic asthma","volume":"54","author":"Radermecker","year":"2018","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.envpol.2023.121722_bib30","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1038\/s41590-019-0496-9","article-title":"Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps","volume":"20","author":"Radermecker","year":"2019","journal-title":"Nat. Immunol."},{"issue":"2","key":"10.1016\/j.envpol.2023.121722_bib31","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1378\/chest.07-1881","article-title":"Differences in airway cytokine profile in severe asthma compared to moderate asthma","volume":"133","author":"Shannon","year":"2008","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.envpol.2023.121722_bib32","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/nm.4332","article-title":"Host DNA released by NETosis promotes rhinovirus-induces type 2 allergic asthma exacerbation","volume":"23","author":"Toussaint","year":"2017","journal-title":"Nat. Med."},{"issue":"5","key":"10.1016\/j.envpol.2023.121722_bib6","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1165\/rcmb.2006-0385OC","article-title":"Prolonged inhaled allergen exposure can induce persistent tolerance","volume":"36","author":"Van Hove","year":"2007","journal-title":"Am J Respir Cell Mol Biol."},{"issue":"3","key":"10.1016\/j.envpol.2023.121722_bib7","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000199715","article-title":"Comparison of acute inflammatory and chronic structural asthma-like responses between C57BL\/6 and BALB\/c mice","volume":"149","author":"Van Hove","year":"2009","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"5","key":"10.1016\/j.envpol.2023.121722_bib33","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1038\/nm.2678","article-title":"Asthma phenotypes: the evolution from clinical to molecular approaches","volume":"18","author":"Wenzel","year":"2012","journal-title":"Nat. Med."},{"issue":"3","key":"10.1016\/j.envpol.2023.121722_bib34","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1164\/ajrccm.156.3.9610046","article-title":"Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids","volume":"156","author":"Wenzel","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"4","key":"10.1016\/j.envpol.2023.121722_bib35","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01495-2019","article-title":"Acute air pollution exposure alters neutrophils in never-smokers and at risk humans","volume":"55","author":"Wooding","year":"2020","journal-title":"Eur. Respir. J."},{"issue":"4\u20136","key":"10.1016\/j.envpol.2023.121722_bib36","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3109\/15419061.2010.551682","article-title":"IL-13 induces mucin 5AC production involging STAT6\/SPDEF in human airway epithelial cells","volume":"17","author":"Yu","year":"2010","journal-title":"Cell Commun. Adhes."},{"issue":"1","key":"10.1016\/j.envpol.2023.121722_bib37","doi-asserted-by":"crossref","first-page":"4320","DOI":"10.1038\/s41598-020-61253-2","article-title":"Plasma NET level is modified by disease severity and inhaled corticosteroids in chronic inflammatory lung diseases","volume":"10","author":"Zs\u00f3fia","year":"2020","journal-title":"Sci. Rep."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749123007248?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749123007248?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T23:04:32Z","timestamp":1759446272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749123007248"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":35,"alternative-id":["S0269749123007248"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2023.121722","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Trajectory of neutrophilic responses in a mouse model of pollutant-aggravated allergic asthma","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2023.121722","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"121722"}}