{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:57:26Z","timestamp":1792616246865,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100008959","name":"Hunan Agricultural University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008959","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.envpol.2024.123402","type":"journal-article","created":{"date-parts":[[2024,1,23]],"date-time":"2024-01-23T05:31:46Z","timestamp":1705987906000},"page":"123402","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Integrated histopathology and transcriptome metabolome profiling reveal the toxicity mechanism of phenazine-1-carboxylic acid in zebrafish"],"prefix":"10.1016","volume":"344","author":[{"given":"Ya","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leyin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-8915","authenticated-orcid":false,"given":"Xiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2024.123402_bib1","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/ja.2015.129","article-title":"New phenazine analogues from streptomyces sp. ifm 11694 with trail resistance-overcoming activities","volume":"6","author":"Abdelfattah","year":"2016","journal-title":"J. Antibiot."},{"key":"10.1016\/j.envpol.2024.123402_bib2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/ja.2010.172","article-title":"Isolation and structure elucidation of izuminosides a-c: a rare phenazine glycosides from streptomyces sp. IFM 11260","volume":"3","author":"Abdelfattah","year":"2011","journal-title":"J. Antibiot."},{"key":"10.1016\/j.envpol.2024.123402_bib3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0045-6535(01)00049-2","article-title":"Embryonic development assay with daphnia magna: application to toxicity of aniline derivatives","volume":"45","author":"Abe","year":"2001","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2024.123402_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.129688","article-title":"Pesticides driven pollution in Kuwait: the first evidence of environmental exposure to pesticides in soils and human health risk assessment","volume":"273","author":"Alshemmari","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2024.123402_bib5","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The Gene Ontology Consortium","volume":"1","author":"Ashburner","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.envpol.2024.123402_bib6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/fes3.112","article-title":"Pesticides, human health, and food security","volume":"3","author":"Bonner","year":"2017","journal-title":"Food Energy Secur."},{"key":"10.1016\/j.envpol.2024.123402_bib7","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/978-1-62703-131-8_4","article-title":"The OECD guidelines for the testing of chemicals and pesticides","volume":"947","author":"Buschmann","year":"2013","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.envpol.2024.123402_bib8","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"Fastp: an ultra-fast all-in-one fasto preprocessor","volume":"17","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.envpol.2024.123402_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147529","article-title":"Isoflucypram cardiovascular toxicity in zebrafish (Danio rerio)","volume":"787","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib10","doi-asserted-by":"crossref","first-page":"710","DOI":"10.3390\/ijms18040710","article-title":"Triazole fungicides inhibit zebrafish hatching by blocking the secretory function of hatching gland cells","volume":"4","author":"De la Paz","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib11","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.aquatox.2009.12.008","article-title":"The fish embryo toxicity test as an animal alternative method in hazard and risk asessmnent and scienifi research","volume":"97","author":"Embry","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2024.123402_bib12","first-page":"387","article-title":"Development and application of microbial pesticide shenqinmycin","volume":"4","author":"Fang","year":"2014","journal-title":"Chin. J. Pesticide Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib13","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1002\/ps.5360","article-title":"Spatiotemporal dynamics of fungicide resistance in the wheat pathogen zymoseptoria tritici in France","volume":"7","author":"Garnault","year":"2019","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib14","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3390\/molecules21050613","article-title":"The effect of Phenazine-1-Carboxylic acid on the morphological, physiological, and molecular characteristics of phellinus noxious","volume":"5","author":"Huang","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.envpol.2024.123402_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126853","article-title":"Lambda-cyhalothrin-loaded nanocapsules pose an unacceptable acute toxicological risk to zebrafish (Danio rerio) at the adult and larval stages but present an acceptable risk to embryos","volume":"422","author":"Huang","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2024.123402_bib16","article-title":"A comprehensive review of 1,2,4-triazole fungicide toxicity in zebrafish (Danio rerio): a mitochondrial and metabolic perspective","volume":"25","author":"Huang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib17","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1080\/09593330.2018.1551429","article-title":"Kinetics, mechanism and identification of photodegradation products of phenazine-1-carboxylic acid","volume":"41","author":"Huasong","year":"2020","journal-title":"Environ. Technol."},{"key":"10.1016\/j.envpol.2024.123402_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125788","article-title":"Embryonic exposure to low concentrations of aflatoxin B1 triggers global transcriptomic changes, defective yolk lipid mobilization, abnormal gastrointestinal tract development and inflammation in Zebrafish","volume":"416","author":"Ivanovics","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2024.123402_bib19","first-page":"1649","article-title":"Phenazine carboxylic acid production and rhizome protective effect of endophytic pseudomonas aeruginosa isolated from zingiber officinale","volume":"5","author":"Jasim","year":"2013","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.envpol.2024.123402_bib20","first-page":"242","article-title":"Effects of different dosage forms of four methoxyacrylate fungicides on acute toxicity of zebrafish","volume":"6","author":"Jia","year":"2016","journal-title":"Asian J. Ecotoxicol."},{"key":"10.1016\/j.envpol.2024.123402_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148777","article-title":"Histology and Multi-omic profiling reveal the mixture toxicity of tebuconazole and difenoconazole in adult zebrafish","volume":"795","author":"Jiang","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib22","doi-asserted-by":"crossref","first-page":"D480","DOI":"10.1093\/nar\/gkm882","article-title":"KEGG for linking genomes to life and the environment","volume":"36","author":"Kanehisa","year":"2007","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.envpol.2024.123402_bib23","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/bfgp\/elr014","article-title":"The use of RNAi technologies for gene knockdown in zebrafish","volume":"4","author":"Kelly","year":"2011","journal-title":"Brief. Funct. Genomics"},{"key":"10.1016\/j.envpol.2024.123402_bib24","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"Hisat: a fast spliced aligner with low memory requirements","volume":"4","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.envpol.2024.123402_bib25","article-title":"A metabolomic, transcriptomic profiling, and mineral nutrient metabolism study of the phytotoxicity mechanism of uranium","volume":"386","author":"Lai","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2024.123402_bib26","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1021\/cr020473j","article-title":"Phenazine natural products: biosynthesis, Synthetic analogues, and biological activity","volume":"3","author":"Laursen","year":"2004","journal-title":"Chem. Rev."},{"key":"10.1016\/j.envpol.2024.123402_bib27","first-page":"2512","article-title":"In tuber biocontrol of potato late blight by a collection of phenazine-1-carboxylic acid-producing pseudomonas spp","volume":"12","author":"Leger","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.envpol.2024.123402_bib28","first-page":"923","article-title":"FeatureCounts: an efficient general purpose program for assigning sequence reads to genomic features","volume":"7","author":"Liao","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.envpol.2024.123402_bib29","article-title":"Phenazine-1-carboxylic acid produced by pseudomonas chlororaphis YL-1 Is effective against acidovorax citrulli","volume":"10","author":"Liu","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.envpol.2024.123402_bib30","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"12","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.envpol.2024.123402_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157525","article-title":"Avoidance responses by danio rerio reveal interactive effects of warming, pesticides and their mixtures","volume":"847","author":"Moreira","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib32","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/978-1-4614-0106-3_15","article-title":"Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases","volume":"2012","author":"Novoa","year":"2012","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.envpol.2024.123402_bib33","first-page":"43","article-title":"Preparation of filter reagent-phenazine-1-carboxylic acid","volume":"1","author":"Ou","year":"1982","journal-title":"Chem. Reagents"},{"key":"10.1016\/j.envpol.2024.123402_bib34","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1021\/acs.jafc.2c08392","article-title":"Natural products-based botanical bactericides discovery: novel abietic acid derivatives as anti-virulence agents for plant disease management","volume":"71","author":"Qi","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.envpol.2024.123402_bib35","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.scitotenv.2018.04.012","article-title":"Mechanisms of developmental toxicity in zebrafish embryos (Danio rerio) induced by boscalid","volume":"634","author":"Qian","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib36","article-title":"Combined effects of organochlorine pesticides on type 2 diabetes mellitus: insights from endocrine disrupting effects of hormones","volume":"341","author":"Shi","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2024.123402_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113417","article-title":"The developmental toxicity and transcriptome analyses of zebrafish (Danio rerio) embryos exposed to carbon nanoparticles","volume":"234","author":"Shi","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2024.123402_bib38","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/tox.20550","article-title":"Early life stage and genetic toxicity of sannous chloride on zebrafish embryos and adults: toxic efects of tin on zebrafish","volume":"26","author":"Sisman","year":"2011","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.envpol.2024.123402_bib39","first-page":"1518","article-title":"Acute toxicity evaluation of different formulations of mesotrione and its original drug on zebrafish","volume":"8","author":"Song","year":"2017","journal-title":"Southern Agric. J."},{"key":"10.1016\/j.envpol.2024.123402_bib40","first-page":"281","volume":"vol. 2","author":"Sun","year":"2008"},{"key":"10.1016\/j.envpol.2024.123402_bib41","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1128\/aem.56.4.908-912.1990","article-title":"Production of the antibiotic phenazine-1-carboxylic acid by fluorescent pseudomonas species in the rhizosphere of wheat","volume":"4","author":"Thomashow","year":"1990","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envpol.2024.123402_bib42","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.envpol.2012.04.008","article-title":"Evaluation of acute toxicity and teratogenic efects of disinfectants by daphnia magna embryo assay","volume":"168","author":"Ton","year":"2012","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2024.123402_bib43","article-title":"Sartools: a DESeq2- and EdgeR-Based R pipeline for comprehensive differential analysis of RNA-Seq data","volume":"6","author":"Varet","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2024.123402_bib44","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.ijbiomac.2018.11.164","article-title":"Models to investigate intussusceptive angiogenesis: a special note on CRISPR\/Cas9 based system in zebrafish","volume":"123","author":"Vimalraj","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.envpol.2024.123402_bib45","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.3390\/molecules28083328","article-title":"Natural products for pesticides discovery: structural diversity derivation and biological activities of naphthoquinones plumbagin and juglone","volume":"28","author":"Wang","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.envpol.2024.123402_bib46","first-page":"13033","article-title":"Comprehensive interrogation of metabolic and bioenergetic responses of early-staged zebrafish (Danio Rerio) to a commercial copper hydroxide nanopesticide","volume":"19","author":"Wang","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2024.123402_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112798","article-title":"Cardiac developmental toxicity and transcriptome analyses of zebrafish (danio rerio) embryos exposed to mancozeb","volume":"226","author":"Wang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2024.123402_bib48","first-page":"1","article-title":"Research progress of multi-omics technology applied to chemical risk assessment","volume":"2","author":"Wei","year":"2021","journal-title":"Asian J. Ecotoxicol."},{"key":"10.1016\/j.envpol.2024.123402_bib49","doi-asserted-by":"crossref","first-page":"13093","DOI":"10.1021\/acs.jafc.2c05284","article-title":"Recent advances in rapid detection techniques for pesticide residue: a review","volume":"41","author":"Xu","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.envpol.2024.123402_bib50","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.605152","article-title":"Isolation of burkholderia sp. Hqb-1, A promising biocontrol bacteria to protect banana against fusarium wilt through phenazine-1-carboxylic acid secretion","volume":"11","author":"Xu","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2024.123402_bib51","first-page":"83","article-title":"Research progress based on the whole life cycle toxicity test of zebrafish","volume":"5","author":"Xue","year":"2019","journal-title":"Asian J. Ecotoxicol."},{"key":"10.1016\/j.envpol.2024.123402_bib52","first-page":"815","article-title":"Application of metabolomics in the field of pesticide environmental toxicology","volume":"5\u20136","author":"Yan","year":"2019","journal-title":"Chin. J. Pesticide Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155025","article-title":"Impairment of the gut health in Danio rerio exposed to triclocarban","volume":"832","author":"Yan","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.123402_bib54","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.jhazmat.2015.12.055","article-title":"Toxic effects of thifluzamide on zebrafish (Danio rerio)","volume":"307","author":"Yang","year":"2016","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2024.123402_bib55","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222212362","article-title":"SDHI fungicide toxicity and associated adverse outcome pathways: what can zebrafish tell us?","volume":"22","author":"Yanicostas","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib56","article-title":"Biomarker responses, gene expression alterations, and histological changes in zebrafish (Danio rerio) after in vivo exposure to polychlorinated diphenyl ethers","volume":"13","author":"Ye","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.envpol.2024.123402_bib57","doi-asserted-by":"crossref","first-page":"7369","DOI":"10.1016\/j.bmcl.2010.10.050","article-title":"Phenazine-1-carboxylic acid derivatives: design, synthesis and biological evaluation against rhizoctonia solani kuhn","volume":"24","author":"Ye","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.envpol.2024.123402_bib58","series-title":"Modern Pesticide Application Technology Diagrammatize","first-page":"344","author":"Yuan","year":"2013"},{"key":"10.1016\/j.envpol.2024.123402_bib59","first-page":"37","article-title":"Prediction of antibody variable region structure based on AlphaFold2 and molecular dynamics stimulation","volume":"1","author":"Yuan","year":"2023","journal-title":"J. Jiangsu Ocean Univ. (Nat. Sci.)"},{"key":"10.1016\/j.envpol.2024.123402_bib60","first-page":"289","article-title":"Antagonistic activity and mode of action of phenazine-1-carboxylic acid, produced by marine bacterium pseudomonas aeruginosa pa31x, against vibrio anguillarum in vitro and in a zebrafish in vivo model","volume":"8","author":"Zhang","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2024.123402_bib61","article-title":"Benoxacor caused developmental and cardiac toxicity in zebrafish larvae","volume":"26","author":"Zhang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2024.123402_bib62","doi-asserted-by":"crossref","first-page":"2532","DOI":"10.3390\/agronomy11122532","article-title":"Inhibition molecular mechanism of the novel fungicidal N-(Naphthalen-1-yl) phenazine-1-carboxamide against Rhizoctonia solani","volume":"12","author":"Zhang","year":"2021","journal-title":"Agronomy"},{"key":"10.1016\/j.envpol.2024.123402_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2021.114638","article-title":"Progress in using zebrafish as a toxicological model for traditional Chinese medicine","volume":"282","author":"Zhang","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.envpol.2024.123402_bib64","first-page":"28","article-title":"Preliminary study on the biological activity of shenqinmycin against Sclerotinia sclerotiorum","volume":"1","author":"Zheng","year":"2011","journal-title":"Chin. J. Pesticide Sci."},{"key":"10.1016\/j.envpol.2024.123402_bib65","first-page":"5","article-title":"Discussion on pesticides and food security in China","volume":"8","author":"Zhou","year":"2014","journal-title":"Pesticide Sci. Adm."},{"key":"10.1016\/j.envpol.2024.123402_bib66","doi-asserted-by":"crossref","first-page":"3733","DOI":"10.1021\/acs.est.2c07734","article-title":"Effects of platinum nanoparticles on rice seedlings (Oryza sativa L.): size-dependent accumulation, transformation and ionomic influence","volume":"57","author":"Zhou","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2024.123402_bib67","first-page":"139","article-title":"Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish","volume":"2","author":"Zhu","year":"2013","journal-title":"J. Appl. Toxicol."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124001167?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124001167?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T23:38:32Z","timestamp":1759448312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749124001167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":67,"alternative-id":["S0269749124001167"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2024.123402","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrated histopathology and transcriptome metabolome profiling reveal the toxicity mechanism of phenazine-1-carboxylic acid in zebrafish","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2024.123402","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"123402"}}