{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T08:41:39Z","timestamp":1792917699577,"version":"4.5.0"},"reference-count":103,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.envpol.2024.124633","type":"journal-article","created":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T22:13:06Z","timestamp":1722118386000},"page":"124633","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Oxidation enhances the toxicity of polyethylene microplastics to mouse eye: Perspective from in vitro and in vivo"],"prefix":"10.1016","volume":"360","author":[{"given":"Ying","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongpeng","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanwen","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingxin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.envpol.2024.124633_bib1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1007\/s11626-016-0061-x","article-title":"Mitochondrial membrane potential (MMP) regulates sperm motility","volume":"52","author":"Agnihotri","year":"2016","journal-title":"In Vitro Cell. Dev. Biol. Anim."},{"issue":"Pt A","key":"10.1016\/j.envpol.2024.124633_bib2","article-title":"Microplastics in the environment: a critical review of current understanding and identification of future research needs","volume":"254","author":"Akdogan","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2024.124633_bib3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.etap.2019.03.001","article-title":"Microplastics in the marine environment: current trends in environmental pollution and mechanisms of toxicological profile","volume":"68","author":"Alimba","year":"2019","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2024.124633_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12915-021-00972-y","article-title":"Plasma membrane integrity: implications for health and disease","volume":"19","author":"Ammendolia","year":"2021","journal-title":"BMC Biol."},{"key":"10.1016\/j.envpol.2024.124633_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2020.111883","article-title":"Worldwide actions against plastic pollution from microbeads and microplastics in cosmetics focusing on European policies. Has the issue been handled effectively?","volume":"162","author":"Anagnosti","year":"2021","journal-title":"Mar. Pollut. Bull."},{"issue":"11","key":"10.1016\/j.envpol.2024.124633_bib6","doi-asserted-by":"crossref","first-page":"7246","DOI":"10.1021\/acs.est.1c01512","article-title":"Weathering plastics as a planetary boundary threat: exposure, fate, and hazards","volume":"55","author":"Arp","year":"2021","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib7","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1023\/A:1020641629319","article-title":"Modified method for evaluation of plasma membrane integrity in eukaryotic cell","volume":"134","author":"Arzumanyan","year":"2002","journal-title":"Bull. Exp. Biol. Med."},{"key":"10.1016\/j.envpol.2024.124633_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134238","article-title":"Aging of microplastics increases their adsorption affinity towards organic contaminants","volume":"298","author":"Bhagat","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2024.124633_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2022.108470","article-title":"Polyethylene microplastics trigger cell apoptosis and inflammation via inducing oxidative stress and activation of the NLRP3 inflammasome in carp gills","volume":"132","author":"Cao","year":"2023","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.envpol.2024.124633_bib10","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1600-0560.2006.00584.x","article-title":"Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: a potential role in skin fibrogenesis","volume":"34","author":"Chaudhuri","year":"2007","journal-title":"J. Cutan. Pathol."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1167\/iovs.16-20009","article-title":"Galectin-3 inhibition by a small-molecule inhibitor reduces both pathological corneal neovascularization and fibrosis","volume":"58","author":"Chen","year":"2017","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"14","key":"10.1016\/j.envpol.2024.124633_bib12","doi-asserted-by":"crossref","first-page":"39894","DOI":"10.1007\/s11356-022-24918-1","article-title":"Adverse effects of pristine and aged polystyrene microplastics in mice and their Nrf2-mediated defense mechanisms with tissue specificity","volume":"30","author":"Cui","year":"2023","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2024.124633_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154963","article-title":"Microplastics in decapod crustaceans: accumulation, toxicity and impacts, a review","volume":"832","author":"D'Costa","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.envpol.2024.124633_bib14","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/j.survophthal.2022.03.001","article-title":"Intraocular pressure measurement: a review","volume":"67","author":"Da Silva","year":"2022","journal-title":"Surv. Ophthalmol."},{"issue":"19","key":"10.1016\/j.envpol.2024.124633_bib15","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.01095-19","article-title":"Plastics: environmental and biotechnological perspectives on microbial degradation","volume":"85","author":"Danso","year":"2019","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envpol.2024.124633_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165076","article-title":"The emerging role of microplastics in systemic toxicity: involvement of reactive oxygen species (ROS)","volume":"895","author":"Das","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib17","doi-asserted-by":"crossref","first-page":"F118","DOI":"10.1152\/ajprenal.00110.2008","article-title":"Structural and functional changes in the kidneys of high-fat diet-induced obese mice","volume":"296","author":"Deji","year":"2009","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.envpol.2024.124633_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132991","article-title":"A review on methods for extracting and quantifying microplastic in biological tissues","volume":"464","author":"Di Fiore","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2024.124633_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/bs.pmbts.2015.04.001","article-title":"Overview of the cornea: structure, function, and development","volume":"134","author":"Eghrari","year":"2015","journal-title":"Prog Mol Biol Transl Sci"},{"key":"10.1016\/j.envpol.2024.124633_bib20","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.biopha.2021.111349","article-title":"Healing potential of Spirulina platensis for skin wounds by modulating bFGF, VEGF, TGF-\u00df1 and \u03b1-SMA genes expression targeting angiogenesis and scar tissue formation in the rat model","volume":"137","author":"Elbialy","year":"2021","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.envpol.2024.124633_bib21","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/PAI.0000000000000299","article-title":"Integration of VEGF and \u03b1-SMA expression improves the prediction accuracy of fibrosis in chronic hepatitis C liver biopsy","volume":"25","author":"Elzamly","year":"2017","journal-title":"Appl. Immunohistochem. Mol. Morphol."},{"issue":"6","key":"10.1016\/j.envpol.2024.124633_bib22","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1002\/em.21708","article-title":"Alterations of GSH and MDA levels and their association with bee venom\u2010induced DNA damage in human peripheral blood leukocytes","volume":"53","author":"Gajski","year":"2012","journal-title":"Environ. Mol. Mutagen."},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib23","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1700782","article-title":"Production, use, and fate of all plastics ever made","volume":"3","author":"Geyer","year":"2017","journal-title":"Sci. Adv."},{"key":"10.1016\/j.envpol.2024.124633_bib24","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/bs.apcsb.2015.11.006","article-title":"Ion channels in the eye: involvement in ocular pathologies","volume":"104","author":"Giblin","year":"2016","journal-title":"Adv Protein Chem Struct Biol"},{"key":"10.1016\/j.envpol.2024.124633_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jtos.2022.05.005","article-title":"Limiting plastic waste in dry eye practice for environmental sustainability","volume":"25","author":"Govindasamy","year":"2022","journal-title":"Ocul. Surf."},{"key":"10.1016\/j.envpol.2024.124633_bib26","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0070-2153(10)90010-0","article-title":"Eye development","volume":"90","author":"Graw","year":"2010","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.envpol.2024.124633_bib27","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.etap.2019.03.007","article-title":"Microplastics in cosmetics: environmental issues and needs for global bans","volume":"68","author":"Guerranti","year":"2019","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2024.124633_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116170","article-title":"The hidden threat of plastic leachates: a critical review on their impacts on aquatic organisms","volume":"184","author":"Gunaalan","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2024.124633_bib29","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1155\/S0962935195000020","article-title":"Apoptosis and inflammation","volume":"4","author":"Haanen","year":"1995","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.envpol.2024.124633_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12974-021-02124-z","article-title":"Uncovering sex differences of rodent microglia","volume":"18","author":"Han","year":"2021","journal-title":"J. Neuroinflammation"},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib31","first-page":"5","article-title":"The effect of corneal edema on visual function","volume":"16","author":"Hess","year":"1977","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.envpol.2024.124633_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124028","article-title":"Reproductive toxicity of polystyrene microplastics: in vivo experimental study on testicular toxicity in mice","volume":"405","author":"Hou","year":"2021","journal-title":"J. Hazard Mater."},{"issue":"12","key":"10.1016\/j.envpol.2024.124633_bib33","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050764","article-title":"20-Hydroxyecdysone protects against oxidative stress-induced neuronal injury by scavenging free radicals and modulating NF-\u03baB and JNK pathways","volume":"7","author":"Hu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.envpol.2024.124633_bib34","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1146\/annurev-vision-100419-115156","article-title":"Retina metabolism and metabolism in the pigmented epithelium: a busy intersection","volume":"7","author":"Hurley","year":"2021","journal-title":"Annual review of vision science"},{"issue":"12","key":"10.1016\/j.envpol.2024.124633_bib35","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1016\/S0886-3350(02)01482-7","article-title":"Retinal nerve fiber layer thickness changes after an acute increase in intraocular pressure","volume":"28","author":"Iester","year":"2002","journal-title":"J. Cataract Refract. Surg."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib36","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1167\/iovs.16-20412","article-title":"Compound 49b regulates ZO-1 and occludin levels in human retinal endothelial cells and in mouse retinal vasculature","volume":"58","author":"Jiang","year":"2017","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.envpol.2024.124633_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.123430","article-title":"Polystyrene microplastics induced male reproductive toxicity in mice","volume":"401","author":"Jin","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2024.124633_bib38","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.scitotenv.2018.08.353","article-title":"Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice","volume":"649","author":"Jin","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.envpol.2024.124633_bib39","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0928-4680(00)00053-5","article-title":"Oxidative stress and apoptosis","volume":"7","author":"Kannan","year":"2000","journal-title":"Pathophysiology"},{"key":"10.1016\/j.envpol.2024.124633_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.116411","article-title":"A preliminary study about the potential risks of the UV-weathered microplastic: the proteome-level changes in the brain in response to polystyrene derived weathered microplastics","volume":"233","author":"Kim","year":"2023","journal-title":"Environ. Res."},{"issue":"6","key":"10.1016\/j.envpol.2024.124633_bib41","article-title":"Analysis of cell viability by the lactate dehydrogenase assay","volume":"2018","author":"Kumar","year":"2018","journal-title":"Cold Spring Harb. Protoc."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib42","doi-asserted-by":"crossref","first-page":"23","DOI":"10.5334\/aogh.4056","article-title":"The minderoo-Monaco commission on plastics and human health","volume":"89","author":"Landrigan","year":"2023","journal-title":"Ann Glob Health"},{"key":"10.1016\/j.envpol.2024.124633_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128431","article-title":"Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice","volume":"430","author":"Lee","year":"2022","journal-title":"J. Hazard Mater."},{"issue":"2","key":"10.1016\/j.envpol.2024.124633_bib44","doi-asserted-by":"crossref","first-page":"H549","DOI":"10.1152\/ajpheart.00708.2002","article-title":"Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation","volume":"284","author":"Levraut","year":"2003","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.envpol.2024.124633_bib45","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.exer.2015.04.020","article-title":"The microglia in healthy and diseased retina","volume":"136","author":"Li","year":"2015","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.envpol.2024.124633_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12989-021-00403-4","article-title":"Airborne particulate matter (PM 2.5) triggers ocular hypertension and glaucoma through pyroptosis","volume":"18","author":"Li","year":"2021","journal-title":"Part. Fibre Toxicol."},{"issue":"19","key":"10.1016\/j.envpol.2024.124633_bib47","article-title":"Red emissive carbon dot superoxide dismutase nanozyme for bioimaging and ameliorating acute lung injury","volume":"33","author":"Liu","year":"2023","journal-title":"Adv. Funct. Mater."},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib48","doi-asserted-by":"crossref","first-page":"3579","DOI":"10.1021\/acs.est.9b00493","article-title":"New insights into the aging behavior of microplastics accelerated by advanced oxidation processes","volume":"53","author":"Liu","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2024.124633_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125193","article-title":"Effect of weathering on environmental behavior of microplastics: properties, sorption and potential risks","volume":"242","author":"Liu","year":"2020","journal-title":"Chemosphere"},{"issue":"23","key":"10.1016\/j.envpol.2024.124633_bib50","doi-asserted-by":"crossref","first-page":"8506","DOI":"10.1021\/acs.est.3c01601","article-title":"High-content screening discovers microplastics released by contact lenses under sunlight","volume":"57","author":"Liu","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"4","key":"10.1016\/j.envpol.2024.124633_bib51","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00003226-199907000-00002","article-title":"Corneal thickness is reduced in dry eye","volume":"18","author":"Liu","year":"1999","journal-title":"Cornea"},{"issue":"Pt C","key":"10.1016\/j.envpol.2024.124633_bib52","article-title":"Polystyrene microplastics induced female reproductive toxicity in mice","volume":"424","author":"Liu","year":"2022","journal-title":"J. Hazard Mater."},{"issue":"Pt A","key":"10.1016\/j.envpol.2024.124633_bib53","article-title":"Environmental behaviors of microplastics in aquatic systems: a systematic review on degradation, adsorption, toxicity and biofilm under aging conditions","volume":"423","author":"Luo","year":"2022","journal-title":"J. Hazard Mater."},{"issue":"Pt 1","key":"10.1016\/j.envpol.2024.124633_bib54","article-title":"Maternal exposure to different sizes of polystyrene microplastics during gestation causes metabolic disorders in their offspring","volume":"255","author":"Luo","year":"2019","journal-title":"Environ. Pollut."},{"issue":"3","key":"10.1016\/j.envpol.2024.124633_bib55","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/S0008-6363(98)00216-8","article-title":"Chronic myocardial infarction in the mouse: cardiac structural and functional change","volume":"41","author":"Lutgens","year":"1999","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.envpol.2024.124633_bib56","series-title":"Intraocular Pressure","author":"Machiele","year":"2018"},{"issue":"6550","key":"10.1016\/j.envpol.2024.124633_bib57","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1126\/science.abg5433","article-title":"The global threat from plastic pollution","volume":"373","author":"MacLeod","year":"2021","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.envpol.2024.124633_bib58","doi-asserted-by":"crossref","first-page":"3928","DOI":"10.1167\/iovs.06-1536","article-title":"Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function","volume":"48","author":"Mandell","year":"2007","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"9451","key":"10.1016\/j.envpol.2024.124633_bib59","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1016\/S0140-6736(04)17554-5","article-title":"The eye in systemic inflammatory diseases","volume":"364","author":"McCluskey","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.envpol.2024.124633_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108243","article-title":"Corneal nerves anatomy, function, injury and regeneration","volume":"200","author":"Medeiros","year":"2020","journal-title":"Exp. Eye Res."},{"issue":"3","key":"10.1016\/j.envpol.2024.124633_bib61","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/bjaceaccp\/mkn015","article-title":"Intraocular pressure","volume":"8","author":"Murgatroyd","year":"2008","journal-title":"Cont. Educ. Anaesth. Crit. Care Pain"},{"issue":"24","key":"10.1016\/j.envpol.2024.124633_bib62","doi-asserted-by":"crossref","first-page":"4527","DOI":"10.1042\/BCJ20160503C","article-title":"Molecular mechanisms of ROS production and oxidative stress in diabetes","volume":"473","author":"Newsholme","year":"2016","journal-title":"Biochem. J."},{"issue":"3","key":"10.1016\/j.envpol.2024.124633_bib63","doi-asserted-by":"crossref","first-page":"561","DOI":"10.3390\/ijms18030561","article-title":"Microglial function across the spectrum of age and gender","volume":"18","author":"Nissen","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.envpol.2024.124633_bib64","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.neuro.2005.06.002","article-title":"Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat","volume":"26","author":"Nucci","year":"2005","journal-title":"Neurotoxicology"},{"issue":"8","key":"10.1016\/j.envpol.2024.124633_bib65","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1073\/pnas.1419921112","article-title":"Elevated intraocular pressure decreases response sensitivity of inner retinal neurons in experimental glaucoma mice","volume":"112","author":"Pang","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib66","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1016\/j.ajpath.2018.03.005","article-title":"The role of microglia and peripheral monocytes in retinal damage after corneal chemical injury","volume":"188","author":"Paschalis","year":"2018","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.envpol.2024.124633_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108115","article-title":"Biological functions of tear film","volume":"197","author":"Pflugfelder","year":"2020","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.envpol.2024.124633_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.134455","article-title":"Environmental exposure to microplastics: an overview on possible human health effects","volume":"702","author":"Prata","year":"2020","journal-title":"Sci. Total Environ."},{"issue":"15","key":"10.1016\/j.envpol.2024.124633_bib69","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.3390\/ani12151979","article-title":"Microplastics in internal tissues of companion animals from urban environments","volume":"12","author":"Prata","year":"2022","journal-title":"Animals"},{"key":"10.1016\/j.envpol.2024.124633_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151642","article-title":"Effects of virgin and weathered polystyrene and polypropylene microplastics on Raphidocelis subcapitata and embryos of Danio rerio under environmental concentrations","volume":"816","author":"Prata","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.124633_bib71","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.scitotenv.2019.01.245","article-title":"Microplastics induce intestinal inflammation, oxidative stress, and disorders of metabolome and microbiome in zebrafish","volume":"662","author":"Qiao","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib72","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1167\/iovs.02-0173","article-title":"Impact of the environment on the mammalian corneal epithelium","volume":"44","author":"Ringvold","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.envpol.2024.124633_bib73","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/etc.4371","article-title":"Rethinking microplastics as a diverse contaminant suite","volume":"38","author":"Rochman","year":"2019","journal-title":"Environ. Toxicol. Chem."},{"issue":"11","key":"10.1016\/j.envpol.2024.124633_bib74","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/nri3086","article-title":"Microglial cell origin and phenotypes in health and disease","volume":"11","author":"Saijo","year":"2011","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.envpol.2024.124633_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155329","article-title":"Assessing exposure of the Australian population to microplastics through bottled water consumption","volume":"837","author":"Samandra","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.envpol.2024.124633_bib76","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/02713683.2014.906625","article-title":"Gender differences in ocular blood flow","volume":"40","author":"Schmidl","year":"2015","journal-title":"Curr. Eye Res."},{"key":"10.1016\/j.envpol.2024.124633_bib77","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.152908","article-title":"Acute oral colchicine caused gastric mucosal injury and disturbance of associated microbiota in mice","volume":"461","author":"Shi","year":"2021","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib78","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1146\/annurev-vision-091517-034425","article-title":"Microglia in the retina: roles in development, maturity, and disease","volume":"4","author":"Silverman","year":"2018","journal-title":"Annual review of vision science"},{"issue":"6","key":"10.1016\/j.envpol.2024.124633_bib79","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.survophthal.2019.04.007","article-title":"Choroidal and retinal thickness in systemic autoimmune and inflammatory diseases: a review","volume":"64","author":"Steiner","year":"2019","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.envpol.2024.124633_bib80","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1007\/s00204-019-02478-7","article-title":"Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo","volume":"93","author":"Stock","year":"2019","journal-title":"Arch. Toxicol."},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib81","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1007\/s00204-019-02478-7","article-title":"Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo","volume":"93","author":"Stock","year":"2019","journal-title":"Arch. Toxicol."},{"issue":"1","key":"10.1016\/j.envpol.2024.124633_bib82","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-36181-x","article-title":"Air pollutant particulate matter 2.5 induces dry eye syndrome in mice","volume":"8","author":"Tan","year":"2018","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib83","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1021\/nn100389a","article-title":"Nanoparticle-induced apoptosis propagates through hydrogen-peroxide-mediated bystander killing: insights from a human intestinal epithelium in vitro model","volume":"4","author":"Thubagere","year":"2010","journal-title":"ACS Nano"},{"issue":"10","key":"10.1016\/j.envpol.2024.124633_bib84","doi-asserted-by":"crossref","first-page":"6518","DOI":"10.1167\/iovs.13-11763","article-title":"Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells","volume":"54","author":"Tien","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"4","key":"10.1016\/j.envpol.2024.124633_bib85","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.1007\/s11356-020-10801-4","article-title":"Rhodamine B dye staining for visualizing microplastics in laboratory-based studies","volume":"28","author":"Tong","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2024.124633_bib86","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.yfrne.2018.11.003","article-title":"Sexual differentiation of microglia","volume":"52","author":"Villa","year":"2019","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.envpol.2024.124633_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.128955","article-title":"Pristine and artificially-aged polystyrene microplastic particles differ in regard to cellular response","volume":"435","author":"V\u00f6lkl","year":"2022","journal-title":"J. Hazard Mater."},{"issue":"11","key":"10.1016\/j.envpol.2024.124633_bib88","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.optm.2008.01.024","article-title":"Sex-and gender-based differences in healthy and diseased eyes","volume":"79","author":"Wagner","year":"2008","journal-title":"Optometry-Journal of the American Optometric Association"},{"issue":"5","key":"10.1016\/j.envpol.2024.124633_bib89","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1097\/IJG.0000000000000200","article-title":"Retinal microglia in glaucoma","volume":"25","author":"Wang","year":"2016","journal-title":"J. Glaucoma"},{"key":"10.1016\/j.envpol.2024.124633_bib90","article-title":"The enhancement in toxic potency of oxidized functionalized polyethylene-microplastics in mice gut and Caco-2 cells","volume":"903","author":"Wang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.124633_bib91","article-title":"Oxidized\/unmodified-polyethylene microplastics neurotoxicity in mice: perspective from microbiota-gut-brain axis","author":"Wang","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2024.124633_bib92","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.141603","article-title":"The toxicity of virgin and UV-aged PVC microplastics on the growth of freshwater algae Chlamydomonas reinhardtii","volume":"749","author":"Wang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2024.124633_bib93","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106659","article-title":"Microplastics induced inflammation and apoptosis via ferroptosis and the NF-\u03baB pathway in carp","volume":"262","author":"Xu","year":"2023","journal-title":"Aquat. Toxicol."},{"issue":"5","key":"10.1016\/j.envpol.2024.124633_bib94","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph17051509","article-title":"Toxicity of microplastics and nanoplastics in mammalian systems","volume":"17","author":"Yong","year":"2020","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envpol.2024.124633_bib95","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.maturitas.2015.10.005","article-title":"Age-related eye disease and gender","volume":"83","author":"Zetterberg","year":"2016","journal-title":"Maturitas"},{"key":"10.1016\/j.envpol.2024.124633_bib96","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s10689-014-9757-9","article-title":"Mitochondrial membrane potential and reactive oxygen species in cancer stem cells","volume":"14","author":"Zhang","year":"2015","journal-title":"Fam. Cancer"},{"issue":"7","key":"10.1016\/j.envpol.2024.124633_bib97","doi-asserted-by":"crossref","first-page":"3740","DOI":"10.1021\/acs.est.9b04535","article-title":"A review of microplastics in table salt, drinking water, and air: direct human exposure","volume":"54","author":"Zhang","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"5","key":"10.1016\/j.envpol.2024.124633_bib98","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1038\/s41401-022-01013-2","article-title":"GDF11 promotes wound healing in diabetic mice via stimulating HIF-1\u0251-VEGF\/SDF-1\u0251-mediated endothelial progenitor cell mobilization and neovascularization","volume":"44","author":"Zhang","year":"2023","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.envpol.2024.124633_bib99","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132503","article-title":"Polystyrene microplastics induce size-dependent multi-organ damage in mice: insights into gut microbiota and fecal metabolites","volume":"461","author":"Zhang","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2024.124633_bib100","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1007\/s11434-011-4689-3","article-title":"Progress in the research of GSH in cells","volume":"56","author":"Zhao","year":"2011","journal-title":"Chin. Sci. Bull."},{"issue":"9","key":"10.1016\/j.envpol.2024.124633_bib101","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.3390\/antiox12091675","article-title":"The applications and mechanisms of superoxide dismutase in medicine, food, and cosmetics","volume":"12","author":"Zheng","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.envpol.2024.124633_bib102","doi-asserted-by":"crossref","DOI":"10.2217\/bmm-2022-0846","article-title":"Oxidative stress-related biomarkers in oral squamous cell carcinoma patients: a systematic review and meta-analysis","author":"Zhou","year":"2023","journal-title":"Biomarkers Med."},{"key":"10.1016\/j.envpol.2024.124633_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119126","article-title":"Polystyrene microplastic particles: in vivo and in vitro ocular surface toxicity assessment","volume":"303","author":"Zhou","year":"2022","journal-title":"Environ. Pollut."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124013472?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124013472?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,14]],"date-time":"2024-09-14T15:27:22Z","timestamp":1726327642000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749124013472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":103,"alternative-id":["S0269749124013472"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2024.124633","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oxidation enhances the toxicity of polyethylene microplastics to mouse eye: Perspective from in vitro and in vivo","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2024.124633","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"124633"}}