{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T04:04:53Z","timestamp":1778126693576,"version":"3.51.4"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T00:00:00Z","timestamp":1728345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003569","name":"Ministry of Food and Drug Safety","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003569","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004085","name":"Ogun Ministry of Education Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.envpol.2024.125092","type":"journal-article","created":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T17:15:29Z","timestamp":1728494129000},"page":"125092","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"P1","title":["Early life air pollution exposures and thyroid function in children: A prospective cohort study"],"prefix":"10.1016","volume":"363","author":[{"given":"You Joung","family":"Heo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2847-2643","authenticated-orcid":false,"given":"Yun Jeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Tae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4023-3269","authenticated-orcid":false,"given":"Dong Wook","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna Inhyang","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bung Nyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun Chul","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Choong Ho","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ah","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1290-5814","authenticated-orcid":false,"given":"Youn Hee","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2024.125092_bib1","series-title":"Korea Environment Corporation","article-title":"AIRKOREA, Confirmed data by sensing station","year":"2021"},{"issue":"9","key":"10.1016\/j.envpol.2024.125092_bib3","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1289\/ehp.1307984","article-title":"Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice","volume":"122","author":"Allen","year":"2014","journal-title":"Environmental health perspectives"},{"issue":"9","key":"10.1016\/j.envpol.2024.125092_bib4","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.1007\/s00204-021-03110-3","article-title":"Dopaminergic and serotonergic changes in rabbit fetal brain upon repeated gestational exposure to diesel engine exhaust","volume":"95","author":"Bernal-Mel\u00e9ndez","year":"2021","journal-title":"Arch. Toxicol."},{"issue":"8","key":"10.1016\/j.envpol.2024.125092_bib5","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1210\/jc.2014-1761","article-title":"Cardiovascular risk factors in children with long-standing untreated idiopathic subclinical hypothyroidism","volume":"99","author":"Cerbone","year":"2014","journal-title":"The Journal of clinical endocrinology and metabolism"},{"issue":"8","key":"10.1016\/j.envpol.2024.125092_bib6","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph18084326","article-title":"The association between preterm birth and ambient air pollution exposure in shiyan, China, 2015-2017","volume":"18","author":"Chen","year":"2021","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"10082","key":"10.1016\/j.envpol.2024.125092_bib7","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1016\/S0140-6736(17)30505-6","article-title":"Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015","volume":"389","author":"Cohen","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.envpol.2024.125092_bib8","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2147\/IJGM.S102230","article-title":"Overview of air pollution and endocrine disorders","volume":"11","author":"Darbre","year":"2018","journal-title":"Int. J. Gen. Med."},{"key":"10.1016\/j.envpol.2024.125092_bib9","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.envint.2019.01.048","article-title":"Ambient air pollution and overweight and obesity in school-aged children in Barcelona, Spain","volume":"125","author":"de Bont","year":"2019","journal-title":"Environ. Int."},{"issue":"Pt A","key":"10.1016\/j.envpol.2024.125092_bib10","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.envres.2015.09.032","article-title":"Early life exposure to ambient air pollution and childhood asthma in China","volume":"143","author":"Deng","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2024.125092_bib11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.rmed.2016.10.016","article-title":"Early life exposure to traffic-related air pollution and allergic rhinitis in preschool children","volume":"121","author":"Deng","year":"2016","journal-title":"Respir. Med."},{"issue":"3","key":"10.1016\/j.envpol.2024.125092_bib12","doi-asserted-by":"crossref","first-page":"R87","DOI":"10.1530\/JOE-14-0025","article-title":"Thyroid hormones in fetal growth and prepartum maturation","volume":"221","author":"Forhead","year":"2014","journal-title":"J. Endocrinol."},{"issue":"10","key":"10.1016\/j.envpol.2024.125092_bib13","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.12902","article-title":"Association of exposure to ambient air pollution with thyroid function during pregnancy","volume":"2","author":"Ghassabian","year":"2019","journal-title":"JAMA Netw. Open"},{"issue":"6","key":"10.1016\/j.envpol.2024.125092_bib14","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1210\/er.2015-1010","article-title":"EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals","volume":"36","author":"Gore","year":"2015","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.envpol.2024.125092_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13044-020-00084-9","article-title":"Elevated serum TSH concentrations are associated with higher BMI Z-scores in southern Iranian children and adolescents","volume":"13","author":"Habib","year":"2020","journal-title":"Thyroid Res."},{"issue":"12","key":"10.1016\/j.envpol.2024.125092_bib16","doi-asserted-by":"crossref","first-page":"2630","DOI":"10.1093\/aje\/kwab187","article-title":"Associations between prenatal exposure to air pollution and congenital hypothyroidism","volume":"190","author":"Harari-Kremer","year":"2021","journal-title":"American journal of epidemiology"},{"issue":"3","key":"10.1016\/j.envpol.2024.125092_bib17","doi-asserted-by":"crossref","first-page":"158","DOI":"10.6065\/apem.2142132.066","article-title":"Ambient air pollution and endocrinologic disorders in childhood","volume":"26","author":"Heo","year":"2021","journal-title":"Ann Pediatr Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.envpol.2024.125092_bib18","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2018.2172","article-title":"Association of prenatal exposure to ambient and traffic-related air pollution with newborn thyroid function: findings from the children's health study","volume":"1","author":"Howe","year":"2018","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.envpol.2024.125092_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.111132","article-title":"Association between prenatal exposure to air pollutants and newborn thyroxine (T4) levels","volume":"197","author":"Irizar","year":"2021","journal-title":"Environ. Res."},{"issue":"4","key":"10.1016\/j.envpol.2024.125092_bib20","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1289\/EHP508","article-title":"Fetal thyroid function, birth weight, and in utero exposure to fine particle air pollution: a birth cohort study","volume":"125","author":"Janssen","year":"2017","journal-title":"Environmental health perspectives"},{"issue":"6","key":"10.1016\/j.envpol.2024.125092_bib21","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1089\/thy.2017.0507","article-title":"Excessive iodine intake and subclinical hypothyroidism in children and adolescents aged 6-19 Years: results of the sixth Korean national health and nutrition examination survey, 2013-2015","volume":"28","author":"Kang","year":"2018","journal-title":"Thyroid : official journal of the American Thyroid Association"},{"key":"10.1016\/j.envpol.2024.125092_bib22","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.envint.2014.10.005","article-title":"A review on the human health impact of airborne particulate matter","volume":"74","author":"Kim","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2024.125092_bib23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.atmosenv.2017.05.006","article-title":"Spatially and chemically resolved source apportionment analysis: case study of high particulate matter event","volume":"162","author":"Kim","year":"2017","journal-title":"Atmos. Environ."},{"issue":"17","key":"10.1016\/j.envpol.2024.125092_bib24","doi-asserted-by":"crossref","first-page":"10315","DOI":"10.5194\/acp-17-10315-2017","article-title":"Regional contributions to particulate matter concentration in the Seoul metropolitan area, South Korea: seasonal variation and sensitivity to meteorology and emissions inventory","volume":"17","author":"Kim","year":"2017","journal-title":"Atmos. Chem. Phys."},{"issue":"4","key":"10.1016\/j.envpol.2024.125092_bib25","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/ije\/dyy070","article-title":"Cohort Profile: the Environment and Development of Children (EDC) study: a prospective children's cohort","volume":"47","author":"Kim","year":"2018","journal-title":"Int. J. Epidemiol."},{"issue":"8","key":"10.1016\/j.envpol.2024.125092_bib26","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgaa338","article-title":"Association between exposure to ambient air pollution and thyroid function in Korean adults","volume":"105","author":"Kim","year":"2020","journal-title":"The Journal of clinical endocrinology and metabolism"},{"issue":"2","key":"10.1016\/j.envpol.2024.125092_bib27","first-page":"492","article-title":"Neuropathological consequences of gestational exposure to concentrated ambient fine and ultrafine particles in the mouse","volume":"156","author":"Klocke","year":"2017","journal-title":"Toxicol. Sci. : an official journal of the Society of Toxicology"},{"issue":"8","key":"10.1016\/j.envpol.2024.125092_bib28","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1210\/jc.2018-00224","article-title":"Thyroid function in early pregnancy, child iq, and autistic traits: a meta-analysis of individual participant data","volume":"103","author":"Levie","year":"2018","journal-title":"The Journal of clinical endocrinology and metabolism"},{"issue":"1","key":"10.1016\/j.envpol.2024.125092_bib29","first-page":"58","article-title":"Development of a semi-quantitative food frequency questionnaire for 391 pre-school children in Korea","volume":"7","author":"Lim","year":"2002","journal-title":"Korean J of Community Nutr"},{"issue":"49","key":"10.1016\/j.envpol.2024.125092_bib30","doi-asserted-by":"crossref","first-page":"74851","DOI":"10.1007\/s11356-022-21102-3","article-title":"Filtered air intervention modulates hypothalamic-pituitary-thyroid\/gonadal axes by attenuating inflammatory responses in adult rats after fine particulate matter (PM2.5) exposure","volume":"29","author":"Liu","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"issue":"1","key":"10.1016\/j.envpol.2024.125092_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3345\/kjp.2008.51.1.1","article-title":"2007 Korean National Growth Charts: review of developmental process and an outlook","volume":"51","author":"Moon","year":"2008","journal-title":"Korean J Pediatr"},{"key":"10.1016\/j.envpol.2024.125092_bib32","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.envpol.2017.06.052","article-title":"Lead and cadmium exposure, higher thyroid antibodies and thyroid dysfunction in Chinese women","volume":"230","author":"Nie","year":"2017","journal-title":"Environmental pollution (Barking, Essex : 1987)"},{"issue":"46","key":"10.1016\/j.envpol.2024.125092_bib33","doi-asserted-by":"crossref","first-page":"36124","DOI":"10.1074\/jbc.M003549200","article-title":"Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways","volume":"275","author":"Nillni","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.envpol.2024.125092_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0088206","article-title":"Iodine status in Turkish populations and exposure to iodide uptake inhibitors","volume":"9","author":"Ozpinar","year":"2014","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.envpol.2024.125092_bib35","doi-asserted-by":"crossref","DOI":"10.3390\/children8050327","article-title":"Effect of air pollution on obesity in children: a systematic review and meta-analysis","volume":"8","author":"Parasin","year":"2021","journal-title":"Children"},{"issue":"26","key":"10.1016\/j.envpol.2024.125092_bib36","doi-asserted-by":"crossref","first-page":"34621","DOI":"10.1007\/s11356-021-13083-6","article-title":"Maternal exposure to O(3) and NO(2) may increase the risk of newborn congenital hypothyroidism: a national data-based analysis in China","volume":"28","author":"Qi","year":"2021","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2024.125092_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151167","article-title":"Association of exposure to PM(2.5)-bound metals with maternal thyroid function in early pregnancy","volume":"810","author":"Qiu","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"12","key":"10.1016\/j.envpol.2024.125092_bib38","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1177\/0748233715602833","article-title":"Correlation between urinary cadmium and thyroid hormones in outdoor workers exposed to urban stressors","volume":"32","author":"Rosati","year":"2016","journal-title":"Toxicol. Ind. Health"},{"issue":"10","key":"10.1016\/j.envpol.2024.125092_bib39","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3345\/cep.2020.00010","article-title":"Air pollution and childhood obesity","volume":"63","author":"Seo","year":"2020","journal-title":"Clinical and experimental pediatrics"},{"issue":"1","key":"10.1016\/j.envpol.2024.125092_bib40","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1186\/s12889-019-7790-1","article-title":"Maternal exposure to PM(2.5) may increase the risk of congenital hypothyroidism in the offspring: a national database based study in China","volume":"19","author":"Shang","year":"2019","journal-title":"BMC Publ. Health"},{"key":"10.1016\/j.envpol.2024.125092_bib41","series-title":"Sperling Pediatric Endocrinology","first-page":"202","year":"2020"},{"issue":"6","key":"10.1016\/j.envpol.2024.125092_bib42","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/humupd\/dmt041","article-title":"The periconceptional period, reproduction and long-term health of offspring: the importance of one-carbon metabolism","volume":"19","author":"Steegers-Theunissen","year":"2013","journal-title":"Hum. Reprod. Update"},{"issue":"2\u20133","key":"10.1016\/j.envpol.2024.125092_bib43","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.tox.2008.05.008","article-title":"Carbaryl, 1-naphthol and 2-naphthol inhibit the beta-1 thyroid hormone receptor-mediated transcription in vitro","volume":"249","author":"Sun","year":"2008","journal-title":"Toxicology"},{"issue":"Suppl. 3","key":"10.1016\/j.envpol.2024.125092_bib44","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/bcpt.13226","article-title":"Pre-natal brain development as a target for urban air pollution","volume":"125","author":"Sunyer","year":"2019","journal-title":"Basic Clin. Pharmacol. Toxicol."},{"issue":"4","key":"10.1016\/j.envpol.2024.125092_bib45","first-page":"339","article-title":"Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic mechanisms","volume":"26","author":"Valavanidis","year":"2008","journal-title":"Journal of environmental science and health Part C, Environmental carcinogenesis & ecotoxicology reviews"},{"issue":"1","key":"10.1016\/j.envpol.2024.125092_bib46","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12940-022-00889-1","article-title":"Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Dibet.es study)","volume":"21","author":"Vald\u00e9s","year":"2022","journal-title":"Environ. Health"},{"issue":"12","key":"10.1016\/j.envpol.2024.125092_bib47","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1289\/ehp.1204918","article-title":"Air pollution exposure and markers of placental growth and function: the generation R study","volume":"120","author":"van den Hooven","year":"2012","journal-title":"Environmental health perspectives"},{"issue":"8","key":"10.1016\/j.envpol.2024.125092_bib48","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1089\/thy.2018.0780","article-title":"Evaluation of maternal exposure to PM(2.5) and its components on maternal and neonatal thyroid function and birth weight: a cohort study. Thyroid","volume":"29","author":"Wang","year":"2019","journal-title":"official journal of the American Thyroid Association"},{"issue":"18","key":"10.1016\/j.envpol.2024.125092_bib50","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph16183464","article-title":"Association between the occurrence of primary hypothyroidism and the exposure of the population near to industrial pollutants in s\u00e3o paulo state, Brazil","volume":"16","author":"Zaccarelli-Marino","year":"2019","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"7","key":"10.1016\/j.envpol.2024.125092_bib51","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1007\/s40618-020-01461-9","article-title":"Climate and air pollution exposure are associated with thyroid function parameters: a retrospective cross-sectional study","volume":"44","author":"Zeng","year":"2021","journal-title":"Journal of endocrinological investigation"},{"issue":"Pt 2","key":"10.1016\/j.envpol.2024.125092_bib52","article-title":"Association of exposure to ambient particulate matter with maternal thyroid function in early pregnancy","volume":"214","author":"Zhang","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2024.125092_bib53","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jhazmat.2018.12.078","article-title":"Air pollution exposure in association with maternal thyroid function during early pregnancy","volume":"367","author":"Zhao","year":"2019","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2024.125092_bib54","article-title":"Perchlorate in fine particulate matter in Shenzhen, China, and implications for human inhalation exposure","author":"Zheng","year":"2022","journal-title":"Environ. Geochem. Health"}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124018098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749124018098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T15:30:35Z","timestamp":1735313435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749124018098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":52,"alternative-id":["S0269749124018098"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2024.125092","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early life air pollution exposures and thyroid function in children: A prospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2024.125092","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"125092"}}