{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:45:12Z","timestamp":1786988712539,"version":"build-2736575974"},"reference-count":81,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82122058"],"award-info":[{"award-number":["82122058"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81773379"],"award-info":[{"award-number":["81773379"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81202165"],"award-info":[{"award-number":["81202165"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2024YFA1802700"],"award-info":[{"award-number":["2024YFA1802700"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["21 ZR1438400"],"award-info":[{"award-number":["21 ZR1438400"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.envpol.2025.125911","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T04:18:13Z","timestamp":1740457093000},"page":"125911","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Identification of the associations between co-exposure to organophosphate flame retardants and thyroid dysfunction and exposure risk factors in residents of Shanghai, China"],"prefix":"10.1016","volume":"370","author":[{"given":"Zhiyuan","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiushuai","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4760-1474","authenticated-orcid":false,"given":"Weiwei","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2025.125911_bib1","doi-asserted-by":"crossref","first-page":"4063","DOI":"10.1007\/s00216-014-7748-1","article-title":"Human biomonitoring of emerging pollutants through non-invasive matrices: state of the art and future potential","volume":"406","author":"Alves","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.envpol.2025.125911_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142750","article-title":"Associations between co-exposure to per- and polyfluoroalkyl substances and organophosphate esters and erythrogram in Chinese adults","volume":"362","author":"An","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2025.125911_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127923","article-title":"Determinants of flame retardants in non-occupationally exposed individuals \u2013 a review","volume":"263","author":"Arvaniti","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2025.125911_bib4","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.tig.2020.03.005","article-title":"Opening the black box: interpretable machine learning for Geneticists","volume":"36","author":"Azodi","year":"2020","journal-title":"Trends Genet."},{"key":"10.1016\/j.envpol.2025.125911_bib5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.envres.2019.02.045","article-title":"Biomonitoring of organophosphate flame retardants and plasticizers in children: associations with house dust and housing characteristics in Japan","volume":"172","author":"Bastiaensen","year":"2019","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2025.125911_bib6","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/biostatistics\/kxu058","article-title":"Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures","volume":"16","author":"Bobb","year":"2015","journal-title":"Biostatistics"},{"key":"10.1016\/j.envpol.2025.125911_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v045.i03","article-title":"Mice: multivariate imputation by chained equations in R","volume":"45","author":"Buuren","year":"2011","journal-title":"J. Stat. Software"},{"key":"10.1016\/j.envpol.2025.125911_bib8","doi-asserted-by":"crossref","first-page":"9519","DOI":"10.1021\/acs.est.0c02237","article-title":"Uptake, accumulation, and biomarkers of PM2.5-associated organophosphate flame retardants in C57BL\/6 mice after chronic exposure at real environmental concentrations","volume":"54","author":"Chen","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.147064","article-title":"A review on the occurrence of organophosphate flame retardants in the aquatic environment in China and implications for risk assessment","volume":"783","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2025.125911_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145404","article-title":"Organophosphorus flame retardants in breast milk from Beijing, China: occurrence, nursing infant's exposure and risk assessment","volume":"771","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2025.125911_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105227","article-title":"Novel and legacy flame retardants in paired human fingernails and indoor dust samples","volume":"133","author":"Chen","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107435","article-title":"Pre- and post-natal exposure of children to organophosphate flame retardants: a nationwide survey in France","volume":"168","author":"Chupeau","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib13","article-title":"Assessment of weighted quantile sum regression for modeling chemical mixtures and cancer risk","volume":"14s2","author":"Czarnota","year":"2015","journal-title":"Cancer Inf."},{"key":"10.1016\/j.envpol.2025.125911_bib14","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.envint.2018.08.010","article-title":"Intrauterine multi-metal exposure is associated with reduced fetal growth through modulation of the placental gene network","volume":"120","author":"Deyssenroth","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib15","doi-asserted-by":"crossref","DOI":"10.1039\/D4AY00787E","article-title":"Organophosphate esters in human serum: a relatively simple and efficient liquid chromatography-mass spectrometry method","author":"Du","year":"2024","journal-title":"Anal. Methods"},{"key":"10.1016\/j.envpol.2025.125911_bib16","doi-asserted-by":"crossref","first-page":"7448","DOI":"10.1021\/acs.est.5b00857","article-title":"Investigating endocrine and physiological parameters of captive American kestrels exposed by diet to selected organophosphate flame retardants","volume":"49","author":"Fernie","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib17","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1021\/acs.est.2c06747","article-title":"Source identification of organophosphate esters through the profiles in proglacial and ocean sediments from Ny-\u00c5lesund, the Arctic","volume":"57","author":"Fu","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2019.113445","article-title":"Multi-exposures to suspected endocrine disruptors in electronic waste recycling workers: associations with thyroid and reproductive hormones","volume":"225","author":"Gravel","year":"2020","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.envpol.2025.125911_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.120083","article-title":"Occurrence and risk assessment of organophosphate esters in global aquatic products","volume":"240","author":"Gu","year":"2023","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2025.125911_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.163083","article-title":"Associations of perchlorate, nitrate, and thiocyanate with metabolic syndrome and its components among US adults: a cross-sectional study from NHANES","volume":"879","author":"Guo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2025.125911_bib21","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.envint.2017.11.019","article-title":"Urinary metabolites of organophosphate esters: concentrations and age trends in Australian children","volume":"111","author":"He","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.toxlet.2017.12.030","article-title":"Organophosphate triesters and selected metabolites enhance binding of thyroxine to human transthyretin in vitro","volume":"285","author":"Hill","year":"2018","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2025.125911_bib23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/1047322X.1990.10389587","article-title":"Estimation of average concentration in the presence of nondetectable values","volume":"5","author":"Hornung","year":"1990","journal-title":"Appl. Occup. Environ. Hyg"},{"key":"10.1016\/j.envpol.2025.125911_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106803","article-title":"Exposure to organophosphate esters in elderly people: relationships of OPE body burdens with indoor air and dust concentrations and food consumption","volume":"157","author":"Hou","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105698","article-title":"Organophosphate esters and their metabolites in paired human whole blood, serum, and urine as biomarkers of exposure","volume":"139","author":"Hou","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib26","doi-asserted-by":"crossref","first-page":"3833","DOI":"10.1007\/s10653-022-01464-w","article-title":"Independent and combined effects of exposure to organophosphate esters on thyroid hormones in children and adolescents","volume":"45","author":"Hu","year":"2023","journal-title":"Environ. Geochem. Health"},{"key":"10.1016\/j.envpol.2025.125911_bib27","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s00128-021-03454-7","article-title":"Industrial production of organophosphate flame retardants (OPFRs): big knowledge gaps need to Be filled?","volume":"108","author":"Huang","year":"2022","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envpol.2025.125911_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1395900","article-title":"Risk nomogram for papillary thyroid microcarcinoma with central lymph node metastasis and postoperative thyroid function follow-up","volume":"15","author":"Huang","year":"2024","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.envpol.2025.125911_bib29","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s40618-018-0930-0","article-title":"Effects of mandatory salt iodization on breast milk, urinary iodine concentrations, and thyroid hormones: is iodine deficiency still a continuing problem?","volume":"42","author":"Isiklar Ozberk","year":"2019","journal-title":"J. Endocrinol. Investig."},{"key":"10.1016\/j.envpol.2025.125911_bib30","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1089\/thy.2024.0346","article-title":"Age-specific reference intervals for thyroid-stimulating hormones and free thyroxine to optimize diagnosis of thyroid disease","volume":"34","author":"Jansen","year":"2024","journal-title":"Thyroid"},{"key":"10.1016\/j.envpol.2025.125911_bib31","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5838","article-title":"A quantile-based g-computation approach to addressing the effects of exposure mixtures","volume":"128","author":"Keil","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2025.125911_bib32","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.chemosphere.2015.02.015","article-title":"Occurrence and dry deposition of organophosphate esters in atmospheric particles over the northern South China Sea","volume":"127","author":"Lai","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2025.125911_bib33","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1136\/oemed-2016-104231","article-title":"Performance of variable selection methods for assessing the health effects of correlated exposures in case\u2013control studies","volume":"75","author":"Lenters","year":"2018","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.envpol.2025.125911_bib34","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.synbio.2021.10.005","article-title":"Using recombinant adhesive proteins as durable and green flame-retardant coatings","volume":"6","author":"Leong","year":"2021","journal-title":"Syn. Syst. Biotechno."},{"key":"10.1016\/j.envpol.2025.125911_bib35","doi-asserted-by":"crossref","first-page":"6887","DOI":"10.1021\/acs.est.7b01289","article-title":"Organophosphate esters in air, snow, and seawater in the North Atlantic and the Arctic","volume":"51","author":"Li","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib36","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1021\/acs.est.1c05956","article-title":"Thyroid hormone disruption by organophosphate esters is mediated by nuclear\/membrane thyroid hormone receptors: in vitro, in vivo, and in silico studies","volume":"56","author":"Li","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib37","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.envint.2019.03.009","article-title":"A review on organophosphate Ester (OPE) flame retardants and plasticizers in foodstuffs: levels, distribution, human dietary exposure, and future directions","volume":"127","author":"Li","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105054","article-title":"Occurrence, distribution and human exposure to 20 organophosphate esters in air, soil, pine needles, river water, and dust samples collected around an airport in New York state, United States","volume":"131","author":"Li","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121941","article-title":"Organophosphate esters concentrations in human serum and their associations with Sj\u00f6gren syndrome","volume":"331","author":"Liao","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2025.125911_bib40","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.aquatox.2012.12.010","article-title":"Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos\/larvae","volume":"128\u2013129","author":"Liu","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2025.125911_bib41","doi-asserted-by":"crossref","first-page":"17825","DOI":"10.1021\/acs.est.2c04759","article-title":"Exposure to novel brominated flame retardants and organophosphate esters and associations with thyroid cancer risk: a case\u2013control study in eastern China","volume":"56","author":"Liu","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib42","doi-asserted-by":"crossref","first-page":"6144","DOI":"10.1021\/acs.est.1c02850","article-title":"Associations between novel and legacy per- and polyfluoroalkyl substances in human serum and thyroid cancer: a case and Healthy population in Shandong province, East China","volume":"56","author":"Liu","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib43","first-page":"104","article-title":"Effects of TDCPP or TPP on gene transcriptions and hormones of HPG axis, and their consequences on reproduction in adult zebrafish (Danio rerio)","volume":"134\u2013135","author":"Liu","year":"2013","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2025.125911_bib44","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1002\/etc.3395","article-title":"Long-term exposure to triphenylphosphate alters hormone balance and HPG, HPI, and HPT gene expression in zebrafish (Danio rerio)","volume":"35","author":"Liu","year":"2016","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2025.125911_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108562","article-title":"Co-exposure to phthalates and polycyclic aromatic hydrocarbons and the risk of gestational hypertension in Chinese women","volume":"185","author":"Liu","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.139237","article-title":"Serum organophosphate flame retardants and plasticizers in Chinese females of childbearing age: association with serum reproductive and thyroid hormones","volume":"337","author":"Liu","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2025.125911_bib47","article-title":"Consistent individualized feature attribution for tree ensembles","author":"Lundberg","year":"2018","journal-title":"ArXiv"},{"key":"10.1016\/j.envpol.2025.125911_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105461","article-title":"Associations between organophosphate esters and sex hormones among 6\u201319-year old children and adolescents in NHANES 2013\u20132014","volume":"136","author":"Luo","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118930","article-title":"Seasonal variation and deposition of atmospheric organophosphate esters in the coastal region of Shanghai, China","volume":"300","author":"Ma","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2025.125911_bib50","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1289\/ehp.0901332","article-title":"House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters","volume":"118","author":"Meeker","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2025.125911_bib51","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.envint.2015.10.005","article-title":"Nail polish as a source of exposure to triphenyl phosphate","volume":"86","author":"Mendelsohn","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib52","doi-asserted-by":"crossref","first-page":"18139","DOI":"10.1021\/acs.est.3c00848","article-title":"Machine learning assisted discovery of interactions between pesticides, phthalates, phenols, and trace elements in child neurodevelopment","volume":"57","author":"Midya","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib53","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s41043-024-00715-z","article-title":"Healthcare utilisation patterns and contributory factors among middle-aged adults: a scoping review","volume":"43","author":"Ng","year":"2024","journal-title":"J. Health Popul. Nutr."},{"key":"10.1016\/j.envpol.2025.125911_bib54","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S2213-8587(21)00045-0","article-title":"Epidemiology and determinants of obesity in China","volume":"9","author":"Pan","year":"2021","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.envpol.2025.125911_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2020.111547","article-title":"Occurrence, analysis and risk assessment of organophosphate esters (OPEs) in biota: a review","volume":"160","author":"Pantelaki","year":"2020","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2025.125911_bib56","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1056\/NEJMra021194","article-title":"Thyroiditis","volume":"348","author":"Pearce","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envpol.2025.125911_bib57","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.envint.2017.01.020","article-title":"Associations between urinary diphenyl phosphate and thyroid function","volume":"101","author":"Preston","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib58","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jes.2015.12.021","article-title":"In vitro assessment of thyroid hormone receptor activity of four organophosphate esters","volume":"45","author":"Ren","year":"2016","journal-title":"J. Environ. Sci."},{"key":"10.1016\/j.envpol.2025.125911_bib59","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1038\/s43587-024-00692-2","article-title":"Nonlinear dynamics of multi-omics profiles during human aging","volume":"4","author":"Shen","year":"2024","journal-title":"Nat. Aging."},{"key":"10.1016\/j.envpol.2025.125911_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107402","article-title":"Exposure of men living in the greater Montreal area to organophosphate esters: association with hormonal balance and semen quality","volume":"166","author":"Siddique","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib61","doi-asserted-by":"crossref","first-page":"14087","DOI":"10.1021\/acs.est.1c04008","article-title":"Relationship between blood trihalomethane concentrations and serum thyroid function measures in U.S. Adults","volume":"55","author":"Sun","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130248","article-title":"Handwipes as indicators to assess organophosphate flame retardants exposure and thyroid hormone effects in e-waste dismantlers","volume":"443","author":"Tang","year":"2023","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2025.125911_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106640","article-title":"Prenatal exposure to organophosphate esters and neonatal thyroid-stimulating hormone levels: a birth cohort study in Wuhan, China","volume":"156","author":"Tao","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.169962","article-title":"Risk of papillary thyroid carcinoma and nodular goiter associated with exposure to semi-volatile organic compounds: a multi-pollutant assessment based on machine learning algorithms","volume":"915","author":"Wang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2025.125911_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105321","article-title":"Estimating renal and hepatic clearance rates of organophosphate esters in humans: impacts of intrinsic metabolism and binding affinity with plasma proteins","volume":"134","author":"Wang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126279","article-title":"Human internal exposure to organophosphate esters: a short review of urinary monitoring on the basis of biological metabolism research","volume":"418","author":"Wang","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2025.125911_bib67","doi-asserted-by":"crossref","first-page":"10991","DOI":"10.1021\/acs.est.7b03367","article-title":"Organophosphorus flame retardants and plasticizers in building and decoration materials and their potential burdens in newly decorated houses in China","volume":"51","author":"Wang","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib68","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1289\/ehp.1409589","article-title":"Cross-sectional associations of serum perfluoroalkyl acids and thyroid hormones in U.S. Adults: variation according to TPOAb and iodine status (NHANES 2007\u20132008)","volume":"124","author":"Webster","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2025.125911_bib69","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.envpol.2014.09.012","article-title":"Organophosphorus flame retardants and plasticizers: sources, occurrence, toxicity and human exposure","volume":"196","author":"Wei","year":"2015","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2025.125911_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108459","article-title":"Associations between serum per- and polyfluoroalkyl substances and thyroid hormones in Chinese adults: a nationally representative cross-sectional study","volume":"184","author":"Xing","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib71","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.envint.2019.03.053","article-title":"Human exposure pathways to organophosphate flame retardants: associations between human biomonitoring and external exposure","volume":"127","author":"Xu","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105056","article-title":"Biomonitoring of organophosphate triesters and diesters in human blood in Jiangsu Province, eastern China: occurrences, associations, and suspect screening of novel metabolites","volume":"131","author":"Ya","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib73","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130517","article-title":"Insights into the geographical distribution, bioaccumulation characteristics, and ecological risks of organophosphate esters","volume":"445","author":"Yan","year":"2023","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2025.125911_bib74","article-title":"Quantitative identification of the co-exposure effects of e-waste pollutants on human oxidative stress by explainable machine learning","author":"Yang","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2025.125911_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148837","article-title":"A review on organophosphate flame retardants in the environment: occurrence, accumulation, metabolism and toxicity","volume":"795","author":"Yao","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2025.125911_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106215","article-title":"Exposure to organophosphate ester flame retardants and plasticizers during pregnancy: thyroid endocrine disruption and mediation role of oxidative stress","volume":"146","author":"Yao","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2025.125911_bib77","doi-asserted-by":"crossref","first-page":"8896","DOI":"10.1021\/acs.est.6b02474","article-title":"Levels of blood organophosphorus flame retardants and association with changes in human sphingolipid homeostasis","volume":"50","author":"Zhao","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2025.125911_bib78","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1039\/C5TX00374A","article-title":"Effects of tris(1,3-dichloro-2-propyl)phosphate on pathomorphology and gene\/protein expression related to thyroid disruption in rats","volume":"5","author":"Zhao","year":"2016","journal-title":"Toxicol. Res."},{"key":"10.1016\/j.envpol.2025.125911_bib79","doi-asserted-by":"crossref","DOI":"10.1177\/11795549241287085","article-title":"Comparison and analysis of clinical features of papillary thyroid cancer complicated with Hashimoto's thyroiditis","volume":"18","author":"Zheng","year":"2024","journal-title":"Clin. Med. Insights Oncol."},{"key":"10.1016\/j.envpol.2025.125911_bib80","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2024.122330","article-title":"Synergistic assessment of multi-scenario urban waterlogging through data-driven decoupling analysis in high-density urban areas: a case study in Shenzhen, China","volume":"369","author":"Zhou","year":"2024","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.envpol.2025.125911_bib81","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1021\/acs.estlett.0c00221","article-title":"Occurrence and profiles of organophosphate esters in infant clothing and raw textiles collected from the United States","volume":"7","author":"Zhu","year":"2020","journal-title":"Environ. Sci. Technol. Lett."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749125002842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749125002842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T18:11:43Z","timestamp":1762279903000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749125002842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":81,"alternative-id":["S0269749125002842"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2025.125911","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of the associations between co-exposure to organophosphate flame retardants and thyroid dysfunction and exposure risk factors in residents of Shanghai, China","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2025.125911","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"125911"}}