{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T12:01:40Z","timestamp":1790596900350,"version":"4.1.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019349","name":"Nanjing Medical Science and Technique Development Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019349","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007289","name":"Nanjing Medical University","doi-asserted-by":"publisher","award":["CMCB202426"],"award-info":[{"award-number":["CMCB202426"]}],"id":[{"id":"10.13039\/501100007289","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Jiangsu Province Natural Science Foundation","doi-asserted-by":"publisher","award":["BK20251735"],"award-info":[{"award-number":["BK20251735"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.envpol.2026.127755","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T16:03:25Z","timestamp":1769875405000},"page":"127755","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Prenatal exposure to multiple insecticides and reduced birth weight: a possible mediating role of plasma metabolomic alterations"],"prefix":"10.1016","volume":"394","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7278-1886","authenticated-orcid":false,"given":"Juan","family":"Wen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junya","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingmin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongmei","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiting","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2026.127755_bib1","doi-asserted-by":"crossref","first-page":"555","DOI":"10.3390\/nu17030555","article-title":"Fetal growth restriction and its metabolism-related long-term outcomes-underlying mechanisms and clinical implications","volume":"17","author":"Adam-Raileanu","year":"2025","journal-title":"Nutrients"},{"key":"10.1016\/j.envpol.2026.127755_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.111539","article-title":"Prenatal exposure to organophosphate and pyrethroid insecticides and the herbicide 2,4-dichlorophenoxyacetic acid and size at birth in urban pregnant women","volume":"201","author":"Balalian","year":"2021","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib3","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.pestbp.2015.04.004","article-title":"The global status of insect resistance to neonicotinoid insecticides","volume":"121","author":"Bass","year":"2015","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.envpol.2026.127755_bib4","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12940-018-0413-y","article-title":"Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression","volume":"17","author":"Bobb","year":"2018","journal-title":"Environ. Health"},{"key":"10.1016\/j.envpol.2026.127755_bib5","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1289\/ehp.6259","article-title":"Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation study","volume":"111","author":"Bradman","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.127755_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxlet.2025.03.001","article-title":"Gender-specific effects of prenatal polystyrene nanoparticle exposure on offspring lung development","volume":"407","author":"Bu","year":"2025","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2026.127755_bib7","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s13253-014-0180-3","article-title":"Characterization of weighted quantile sum regression for highly correlated data in a risk analysis setting","volume":"20","author":"Carrico","year":"2015","journal-title":"J. Agric. Biol. Environ. Stat."},{"key":"10.1016\/j.envpol.2026.127755_bib8","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ejogrb.2014.06.016","article-title":"CYP17A1 gene polymorphisms and environmental exposure to organochlorine pesticides contribute to the risk of small for gestational age","volume":"180","author":"Chand","year":"2014","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.envpol.2026.127755_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.136603","article-title":"Association of maternal pyrethroid pesticides exposure during the whole pregnancy with neonate lipid metabolism: a prospective birth cohort, Yunnan, China","volume":"484","author":"Chen","year":"2025","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib10","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/aje\/kwy143","article-title":"Associations of maternal exposure to dichlorodiphenyltrichloroethane and pyrethroids with birth outcomes among participants in the Venda health examination of mothers, babies and their environment residing in an area sprayed for malaria control","volume":"188","author":"Chevrier","year":"2019","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envpol.2026.127755_bib11","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.tox.2012.07.011","article-title":"Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity","volume":"307","author":"Costa","year":"2013","journal-title":"Toxicology"},{"key":"10.1016\/j.envpol.2026.127755_bib12","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.neuro.2024.06.007","article-title":"Developmental pyrethroid exposure in mouse leads to disrupted brain metabolism in adulthood","volume":"103","author":"Curtis","year":"2024","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.envpol.2026.127755_bib13","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.12998\/wjcc.v11.i13.2855","article-title":"Long-term implications of fetal growth restriction","volume":"11","author":"D'Agostin","year":"2023","journal-title":"World J. Clin. Cases"},{"key":"10.1016\/j.envpol.2026.127755_bib14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.reprotox.2017.12.008","article-title":"Associations of maternal exposure to organophosphate and pyrethroid insecticides and the herbicide 2,4-D with birth outcomes and anogenital distance at 3 months in the odense Child cohort","volume":"76","author":"Dalsager","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envpol.2026.127755_bib15","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/jes.2014.86","article-title":"Prenatal exposure to pyrethroid insecticides and birth outcomes in rural Northern China","volume":"25","author":"Ding","year":"2015","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envpol.2026.127755_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114305","article-title":"Maternal exposure to metal mixtures during early pregnancy and fetal growth in the Jiangsu birth cohort, China","volume":"215","author":"Dou","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib17","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/d41573-021-00107-6","article-title":"BCKDK: an emerging kinase target for metabolic diseases and cancer","volume":"20","author":"East","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.envpol.2026.127755_bib18","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/s41370-023-00530-4","article-title":"Prenatal exposure to persistent and non-persistent chemical mixtures and associations with adverse birth outcomes in the Atlanta African American maternal-child cohort","volume":"34","author":"Eick","year":"2024","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envpol.2026.127755_bib19","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1016\/S0140-6736(18)30312-X","article-title":"Origins of lifetime health around the time of conception: causes and consequences","volume":"391","author":"Fleming","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.envpol.2026.127755_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.127494","article-title":"Advances in organophosphorus pesticides pollution: current status and challenges in ecotoxicological, sustainable agriculture, and degradation strategies","volume":"424","author":"Fu","year":"2022","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.116410","article-title":"Effect of prenatal exposure to organophosphates and pyrethroid pesticides on neonatal anthropometric measures and gestational age","volume":"232","author":"Gimenez-Asensio","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib22","doi-asserted-by":"crossref","first-page":"1527S","DOI":"10.1093\/jn\/135.6.1527S","article-title":"Overview of the molecular and biochemical basis of branched-chain amino acid catabolism","volume":"135","author":"Harris","year":"2005","journal-title":"J. Nutr."},{"key":"10.1016\/j.envpol.2026.127755_bib23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.reprotox.2017.05.004","article-title":"Combined exposure to low doses of pesticides causes decreased birth weights in rats","volume":"72","author":"Hass","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envpol.2026.127755_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113019","article-title":"Urinary organophosphate metabolite concentrations and birth sizes among women conceiving through in vitro fertilization in Shanghai, China","volume":"211","author":"Hu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/CS20060339","article-title":"Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches","volume":"113","author":"Jansson","year":"2007","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.envpol.2026.127755_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105219","article-title":"Exposures to chemical mixtures during pregnancy and neonatal outcomes: the HOME study","volume":"134","author":"Kalloo","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib27","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5838","article-title":"A quantile-based g-Computation approach to addressing the effects of exposure mixtures","volume":"128","author":"Keil","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.127755_bib28","doi-asserted-by":"crossref","first-page":"dev202088","DOI":"10.1242\/dev.202088","article-title":"Maternal-fetal cross-talk via the placenta: influence on offspring development and metabolism","volume":"150","author":"Kramer","year":"2023","journal-title":"Development"},{"key":"10.1016\/j.envpol.2026.127755_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2025.125432","article-title":"Neonicotinoid insecticides in non-target organisms: occurrence, exposure, toxicity, and human health risks","volume":"383","author":"Li","year":"2025","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.envpol.2026.127755_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.reprotox.2025.108996","article-title":"Maternal exposure to polystyrene nanoplastics leads to ovotoxicity in female mouse offspring","volume":"137","author":"Liu","year":"2025","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envpol.2026.127755_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2025.104793","article-title":"Gestational exposure to organophosphate pesticides and maternal urine metabolomic profile in the GENEIDA birth cohort","volume":"118","author":"Lopez-Flores","year":"2025","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2026.127755_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.138792","article-title":"Prenatal pesticide exposure and adverse reproductive outcomes: epidemiological evidence and mechanistic insights","volume":"494","author":"Ma","year":"2025","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib33","doi-asserted-by":"crossref","first-page":"576","DOI":"10.3390\/toxics13070576","article-title":"Neonicotinoid-induced cytotoxicity: insights into cellular mechanisms and health risks","volume":"13","author":"Ma","year":"2025","journal-title":"Toxics"},{"key":"10.1016\/j.envpol.2026.127755_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116630","article-title":"A nationwide study of occurrence and exposure assessment of neonicotinoid insecticides and their metabolites in drinking water of China","volume":"189","author":"Mahai","year":"2021","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2026.127755_bib35","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1289\/ehp.1206015","article-title":"Population-based biomonitoring of exposure to organophosphate and pyrethroid pesticides in New York city","volume":"121","author":"McKelvey","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.127755_bib36","doi-asserted-by":"crossref","first-page":"C518","DOI":"10.1152\/ajpcell.00062.2016","article-title":"Ketoisocaproic acid, a metabolite of leucine, suppresses insulin-stimulated glucose transport in skeletal muscle cells in a BCAT2-dependent manner","volume":"311","author":"Moghei","year":"2016","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.envpol.2026.127755_bib37","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.envres.2015.06.035","article-title":"Associations of maternal organophosphate pesticide exposure and PON1 activity with birth outcomes in SAWASDEE birth cohort, Thailand","volume":"142","author":"Naksen","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib38","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.cmet.2012.01.024","article-title":"Interplay between lipids and branched-chain amino acids in development of insulin resistance","volume":"15","author":"Newgard","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.envpol.2026.127755_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107180","article-title":"Prenatal neonicotinoid insecticides exposure, oxidative stress, and birth outcomes","volume":"163","author":"Pan","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib40","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1001\/jamaneurol.2025.2818","article-title":"Brain abnormalities in children exposed prenatally to the pesticide chlorpyrifos","volume":"82","author":"Peterson","year":"2025","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.envpol.2026.127755_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.140019","article-title":"Prospective associations of in utero exposure to multiple insecticides with cord blood mitochondria DNA copy number and longitudinal offspring telomere length shortening","volume":"498","author":"Qiu","year":"2025","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib42","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1289\/ehp.1104615","article-title":"Associations of prenatal exposure to organophosphate pesticide metabolites with gestational age and birth weight","volume":"120","author":"Rauch","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.127755_bib43","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/uog.17347","article-title":"International estimated fetal weight standards of the INTERGROWTH-21(st) project","volume":"49","author":"Stirnemann","year":"2017","journal-title":"Ultrasound Obstet. Gynecol."},{"key":"10.1016\/j.envpol.2026.127755_bib44","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s11306-007-0082-2","article-title":"Proposed minimum reporting standards for chemical analysis chemical analysis working group (CAWG) metabolomics standards initiative (MSI)","volume":"3","author":"Sumner","year":"2007","journal-title":"Metabolomics"},{"key":"10.1016\/j.envpol.2026.127755_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118361","article-title":"High-resolution metabolomics of exposure to tobacco smoke during pregnancy and adverse birth outcomes in the Atlanta African American maternal-child cohort","volume":"292","author":"Tan","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.127755_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118200","article-title":"Organophosphate esters in surface soils from a heavily urbanized region of Eastern China: occurrence, distribution, and ecological risk assessment","volume":"291","author":"Tang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.127755_bib47","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.toxlet.2025.08.006","article-title":"Cuproptosis is involved in small intestinal toxicity in the paraffins during pregnancy","volume":"412","author":"Tang","year":"2025","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.envpol.2026.127755_bib48","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S2213-8587(22)00215-7","article-title":"Association between fetal abdominal growth trajectories, maternal metabolite signatures early in pregnancy, and childhood growth and adiposity: prospective observational multinational INTERBIO-21st fetal study","volume":"10","author":"Villar","year":"2022","journal-title":"Lancet Diabetes Endocrinol."},{"key":"10.1016\/j.envpol.2026.127755_bib49","doi-asserted-by":"crossref","DOI":"10.1289\/EHP12097","article-title":"Association of prenatal exposure to organophosphate, pyrethroid, and neonicotinoid insecticides with child neurodevelopment at 2 years of age: a prospective cohort study","volume":"131","author":"Wang","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.127755_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.169565","article-title":"Urinary biomarkers of exposure to organophosphate, pyrethroid, neonicotinoid insecticides and oxidative stress: a repeated measurement analysis among pregnant women","volume":"912","author":"Wang","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.127755_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.126069","article-title":"Pentachlorophenol exposure, plasma metabolomic markers, and gestational diabetes mellitus: association and potential mediation analyses","volume":"372","author":"Wen","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.127755_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.126965","article-title":"Serum neonicotinoid insecticides levels and gestational diabetes mellitus: mediation by plasma metabolomic alterations","volume":"384","author":"Wen","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.127755_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2025.137625","article-title":"Newborn metabolomic signatures of maternal vanadium exposure and reduced birth size","volume":"489","author":"Xie","year":"2025","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.109087","article-title":"Metabolomics study and meta-analysis on the association between maternal pesticide exposome and birth outcomes","volume":"182","author":"Yang","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.109111","article-title":"Prenatal exposure to neonicotinoid insecticides, fetal endocrine hormones and birth size: findings from SMBCS","volume":"193","author":"Zhang","year":"2024","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107201","article-title":"Human exposure to neonicotinoids and the associated health risks: a review","volume":"163","author":"Zhang","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib57","first-page":"275","article-title":"Prenatal pyrethroid insecticide exposure and thyroid hormone levels and birth sizes of neonates","volume":"488\u2013489","author":"Zhang","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.127755_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114953","article-title":"Environmental occurrence, toxicity concerns, and biodegradation of neonicotinoid insecticides","volume":"218","author":"Zhang","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.127755_bib59","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.envint.2018.11.076","article-title":"Association between exposure to a mixture of phenols, pesticides, and phthalates and obesity: Comparison of three statistical models","volume":"123","author":"Zhang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132602","article-title":"Exposure to PM(2.5), seminal plasma metabolome, and semen quality among Chinese adult men: association and potential mediation analyses","volume":"461","author":"Zhang","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.127755_bib61","doi-asserted-by":"crossref","first-page":"6656","DOI":"10.1038\/s41467-022-34537-6","article-title":"Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking","volume":"13","author":"Zhou","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2026.127755_bib62","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.envint.2018.12.018","article-title":"Inter-day and inter-individual variability in urinary concentrations of melamine and cyanuric acid","volume":"123","author":"Zhu","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envpol.2026.127755_bib63","doi-asserted-by":"crossref","first-page":"7859","DOI":"10.1021\/acs.est.9b02040","article-title":"Occurrence of melamine and its derivatives in breast milk from the United States and its implications for exposure in infants","volume":"53","author":"Zhu","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2026.127755_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.123362","article-title":"Exposure to organophosphate, pyrethroid, and neonicotinoid insecticides and dyslexia: association with oxidative stress","volume":"344","author":"Zhu","year":"2024","journal-title":"Environ. Pollut."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126001259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126001259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:36:56Z","timestamp":1790595416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749126001259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":64,"alternative-id":["S0269749126001259"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2026.127755","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal exposure to multiple insecticides and reduced birth weight: a possible mediating role of plasma metabolomic alterations","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2026.127755","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"127755"}}