{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T03:48:42Z","timestamp":1776829722564,"version":"3.51.2"},"reference-count":73,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018542","name":"Natural Science Foundation of Sichuan Province","doi-asserted-by":"publisher","award":["2024NSFSC1970"],"award-info":[{"award-number":["2024NSFSC1970"]}],"id":[{"id":"10.13039\/501100018542","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270548"],"award-info":[{"award-number":["32270548"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200403"],"award-info":[{"award-number":["32200403"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.envpol.2026.128041","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T06:47:47Z","timestamp":1774939667000},"page":"128041","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["The health threat of wild animals by Rank I ARGs from habitat soils: Metagenomic and metabolomic evidence"],"prefix":"10.1016","volume":"398","author":[{"given":"Jiaying","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumei","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoyang","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuzhen","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2026.128041_bib1","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.scitotenv.2015.01.046","article-title":"Microbiological characterization of aquatic microbiomes targeting taxonomical marker genes and antibiotic resistance genes of opportunistic bacteria","volume":"512\u2013513","author":"Alexander","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128041_bib2","series-title":"Soil Agrochemical Analysis","author":"Bao","year":"2000"},{"key":"10.1016\/j.envpol.2026.128041_bib3","series-title":"The Effects of L-arabinose on the Gut Microbiome","author":"Bao","year":"2025"},{"key":"10.1016\/j.envpol.2026.128041_bib4","first-page":"2215","article-title":"Progresses of study on integrative and conjugative elements of bacteria","volume":"42","author":"Bie","year":"2015","journal-title":"Microbiology China"},{"key":"10.1016\/j.envpol.2026.128041_bib5","doi-asserted-by":"crossref","first-page":"4650","DOI":"10.1016\/j.cub.2021.08.010","article-title":"The oral microbiota of wild bears in Sweden reflects the history of antibiotic use by humans","volume":"31","author":"Brealey","year":"2021","journal-title":"Curr. Biol."},{"key":"10.1016\/j.envpol.2026.128041_bib6","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/s41579-021-00534-7","article-title":"Examining horizontal gene transfer in microbial communities","volume":"19","author":"Brito","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envpol.2026.128041_bib7","first-page":"1435","article-title":"Research advances in ecological risk of antibiotic resistance genes","volume":"33","author":"Cai","year":"2022","journal-title":"Chin. J. Appl. Ecol."},{"key":"10.1016\/j.envpol.2026.128041_bib8","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1038\/s41396-020-0634-2","article-title":"The microbiome and resistome of chimpanzees, gorillas, and humans across host lifestyle and geography","volume":"14","author":"Campbell","year":"2020","journal-title":"ISME J."},{"key":"10.1016\/j.envpol.2026.128041_bib9","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/s42255-018-0017-4","article-title":"Microbial regulation of organismal energy homeostasis","volume":"1","author":"Cani","year":"2019","journal-title":"Nat. Metab."},{"key":"10.1016\/j.envpol.2026.128041_bib10","first-page":"745","article-title":"Utilization of mannan-oligosaccharides by probiotics and human intestinal microflora","volume":"28","author":"Chen","year":"2016","journal-title":"Chin. J. Microecol."},{"key":"10.1016\/j.envpol.2026.128041_bib11","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1038\/s41422-019-0202-3","article-title":"Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria","volume":"29","author":"Chen","year":"2019","journal-title":"Cell Res."},{"key":"10.1016\/j.envpol.2026.128041_bib12","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1042\/BCJ20253024","article-title":"The more we learn, the more diverse it gets: structures, functions and evolution in the Phosphofructokinase Superfamily","volume":"482","author":"Compton","year":"2025","journal-title":"Biochem. J."},{"key":"10.1016\/j.envpol.2026.128041_bib13","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41575-019-0157-3","article-title":"The role of short-chain fatty acids in microbiota-gut-brain communication","volume":"16","author":"Dalile","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.envpol.2026.128041_bib14","first-page":"1138","article-title":"Whole genome sequencing reveals the distribution of resistance and virulence genes of pathogenic Escherichia coli CCHTP from giant panda","volume":"41","author":"Deng","year":"2019","journal-title":"Hereditas (Beijing)"},{"key":"10.1016\/j.envpol.2026.128041_bib15","first-page":"399","article-title":"Advances and prospects of gut microbiome in wild mammals","volume":"37","author":"Ding","year":"2017","journal-title":"Acta Theriol. Sin."},{"key":"10.1016\/j.envpol.2026.128041_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1574-6941.2012.01461.x","article-title":"Low iron availability in continuous in vitro colonic fermentations induces strong dysbiosis of the child gut microbial consortium and a decrease in main metabolites","volume":"83","author":"Dostal","year":"2013","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.envpol.2026.128041_bib17","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s40168-024-01983-x","article-title":"Regional antimicrobial resistance gene flow among the one Health sectors in China","volume":"13","author":"Feng","year":"2025","journal-title":"Microbiome"},{"key":"10.1016\/j.envpol.2026.128041_bib18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s00438-018-1507-5","article-title":"Intensive targeting of regulatory competence genes by transposable elements in streptococci","volume":"294","author":"Fl\u00e9chard","year":"2019","journal-title":"Mol Genet Genomics"},{"key":"10.1016\/j.envpol.2026.128041_bib19","article-title":"Protein domains of unknown function are essential in bacteria","volume":"5","author":"Goodacre","year":"2013","journal-title":"mBio"},{"key":"10.1016\/j.envpol.2026.128041_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecolind.2023.110228","article-title":"Construction and evaluation of ecological networks among natural protected areas based on \u201cquality-structure\u2013function\u201d: a case study of the Qinghai-Tibet area","volume":"151","author":"Gu","year":"2023","journal-title":"Ecol. Indic."},{"key":"10.1016\/j.envpol.2026.128041_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.115521","article-title":"Metagenomic assembly and binning analyses the prevalence and spread of antibiotic resistome in water and fish gut microbiomes along an environmental gradient","volume":"318","author":"Guan","year":"2022","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.envpol.2026.128041_bib22","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s11684-017-0531-x","article-title":"The antibiotic resistome: gene flow in environments, animals and human beings","volume":"11","author":"Hu","year":"2017","journal-title":"Front. Med."},{"key":"10.1016\/j.envpol.2026.128041_bib23","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1360\/TB-2022-0594","article-title":"Organic contaminants influence the horizontal transfer of antibiotic resistance genes","volume":"67","author":"Hu","year":"2022","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.envpol.2026.128041_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/ece3.11435","article-title":"Effects of antibiotic resistance genes on health risks of rivers in habitat of wild animals under human disturbance \u2013 based on analysis of antibiotic resistance genes and virulence factors in microbes of river sediments","volume":"14","author":"Hu","year":"2024","journal-title":"Ecol. Evol."},{"key":"10.1016\/j.envpol.2026.128041_bib25","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/1749-4877.12490","article-title":"Human activities and elevational constraints restrict ranging patterns of snub-nosed monkeys in a mountainous refuge","volume":"16","author":"Huang","year":"2021","journal-title":"Integr. Zool."},{"key":"10.1016\/j.envpol.2026.128041_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.156178","article-title":"Global landscape of gut microbiome diversity and antibiotic resistomes across vertebrates","volume":"838","author":"Huang","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128041_bib27","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1111\/1749-4877.12510","article-title":"Multidrug-resistant Proteus mirabilis isolates carrying blaOXA-1 and blaNDM-1 from wildlife in China: increasing public health risk","volume":"16","author":"Kang","year":"2021","journal-title":"Integr. Zool."},{"key":"10.1016\/j.envpol.2026.128041_bib28","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s00203-024-03834-7","article-title":"Butyrate's (a short-chain fatty acid) microbial synthesis, absorption, and preventive roles against colorectal and lung cancer","volume":"206","author":"Karim","year":"2024","journal-title":"Arch. Microbiol."},{"key":"10.1016\/j.envpol.2026.128041_bib29","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/s42523-025-00448-2","article-title":"Microbial exchange at the wildlife-livestock interface: insights into microbial composition, antimicrobial resistance and virulence factor gene dynamics in grassland ecosystems","volume":"7","author":"Kauer","year":"2025","journal-title":"anim microbiome"},{"key":"10.1016\/j.envpol.2026.128041_bib30","doi-asserted-by":"crossref","first-page":"D698","DOI":"10.1093\/nar\/gkn813","article-title":"EVOG: a database for evolutionary analysis of overlapping genes","volume":"37","author":"Kim","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.envpol.2026.128041_bib31","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: Short-Chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.envpol.2026.128041_bib32","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s41579-020-0438-4","article-title":"Gut microbial metabolites as multi-kingdom intermediates","volume":"19","author":"Krautkramer","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envpol.2026.128041_bib33","doi-asserted-by":"crossref","DOI":"10.1126\/science.abb5352","article-title":"Diversity and functional landscapes in the microbiota of animals in the wild","volume":"372","author":"Levin","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.envpol.2026.128041_bib34","article-title":"SXT\/R391 integrative and conjugative elements in Proteus species reveal abundant genetic diversity and multidrug resistance","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2026.128041_bib35","article-title":"Global health risks lurking in livestock resistome","volume":"11","author":"Li","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.envpol.2026.128041_bib36","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1093\/jac\/dkab450","article-title":"Antimicrobial-induced horizontal transfer of antimicrobial resistance genes in bacteria: a mini-review","volume":"77","author":"Liu","year":"2022","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.envpol.2026.128041_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154739","article-title":"Dispersal of antibiotic resistance genes in an agricultural influenced multi-branch river network","volume":"830","author":"Lu","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128041_bib38","first-page":"745","article-title":"Horizontal transfer of antibiotic resistance genes in the human intestinal flora","volume":"48","author":"Luo","year":"2023","journal-title":"Chin. J. Antibiot."},{"key":"10.1016\/j.envpol.2026.128041_bib39","doi-asserted-by":"crossref","first-page":"326","DOI":"10.2337\/db22-0552","article-title":"Rhamnose displays an anti-obesity effect through stimulation of adipose dopamine receptors and thermogenesis","volume":"72","author":"Lv","year":"2023","journal-title":"Diabetes"},{"key":"10.1016\/j.envpol.2026.128041_bib40","doi-asserted-by":"crossref","first-page":"119303","DOI":"10.1016\/j.jenvman.2023.119303","article-title":"Poultry manure-derived microorganisms as a reservoir and source of antibiotic resistance genes transferred to soil autochthonous microorganisms","volume":"348","author":"M\u0119cik","year":"2023","journal-title":"Journal of Environmental Management"},{"key":"10.1016\/j.envpol.2026.128041_bib41","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.ijbiomac.2022.01.049","article-title":"Chitin derivatives ameliorate DSS-induced ulcerative colitis by changing gut microbiota and restoring intestinal barrier function","volume":"202","author":"Mei","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.envpol.2026.128041_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114212","article-title":"Antibiotic resistant genes in the environment-exploring surveillance methods and sustainable remediation strategies of antibiotics and ARGs","volume":"215","author":"Nava","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.128041_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117453","article-title":"Antimicrobial resistance in Galapagos tortoises as an indicator of the growing human footprint","volume":"284","author":"Nieto-Claudin","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.128041_bib72","doi-asserted-by":"crossref","first-page":"30409","DOI":"10.1074\/jbc.R200006200","article-title":"The Key Role of Anaplerosis and Cataplerosis for Citric Acid Cycle Function","volume":"277","author":"Owen","year":"2002","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.envpol.2026.128041_bib44","doi-asserted-by":"crossref","first-page":"266","DOI":"10.5187\/jast.2023.e129","article-title":"Antibiotic resistance in livestock, environment and humans: one Health perspective","volume":"66","author":"Pandey","year":"2024","journal-title":"J. Anim. Sci. Technol."},{"key":"10.1016\/j.envpol.2026.128041_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148259","article-title":"Co-occurrence of antimicrobial and metal resistance genes in pig feces and agricultural fields fertilized with slurry","volume":"792","author":"Peng","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128041_bib46","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1196\/annals.1419.015","article-title":"Enzymology of the wood-ljungdahl pathway of acetogenesis","volume":"1125","author":"Ragsdale","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.envpol.2026.128041_bib47","doi-asserted-by":"crossref","first-page":"15167","DOI":"10.1021\/acs.est.2c03919","article-title":"A Carotenoid- and nuclease-producing bacterium can mitigate Enterococcus faecalis transformation by antibiotic resistance genes","volume":"56","author":"Ren","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2026.128041_bib48","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1002\/imt2.12","article-title":"Majorbio Cloud: a one\u2010stop, comprehensive bioinformatic platform for multiomics analyses","volume":"1","author":"Ren","year":"2022","journal-title":"iMeta"},{"key":"10.1016\/j.envpol.2026.128041_bib49","series-title":"Generalized Linear Mixed Models with Applications in Agriculture and Biology","first-page":"43","article-title":"Generalized Linear models","author":"Salinas Ru\u00edz","year":"2023"},{"key":"10.1016\/j.envpol.2026.128041_bib50","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41522-025-00746-2","article-title":"Comprehensive genome catalog analysis of the resistome, virulome and mobilome in the wild rodent gut microbiota","volume":"11","author":"Shang","year":"2025","journal-title":"NPJ Biofilms Microbiomes"},{"key":"10.1016\/j.envpol.2026.128041_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.anaerobe.2024.102819","article-title":"Bacteroides and related species: the keystone taxa of the human gut microbiota","volume":"85","author":"Shin","year":"2024","journal-title":"Anaerobe"},{"key":"10.1016\/j.envpol.2026.128041_bib73","doi-asserted-by":"crossref","first-page":"13882","DOI":"10.1021\/acs.jafc.2c04641","article-title":"\u03b1-Ketoglutarate Restores Intestinal Barrier Function through Promoting Intestinal Stem Cells-Mediated Epithelial Regeneration in Colitis","volume":"70","author":"Si","year":"2022","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"10.1016\/j.envpol.2026.128041_bib52","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00206-25","article-title":"Complex interplay between gene deletions and the environment uncovers cellular roles for genes of unknown function in Escherichia coli","volume":"10","author":"Sondervorst","year":"2025","journal-title":"mSystems"},{"key":"10.1016\/j.envpol.2026.128041_bib53","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1021\/bi00122a037","article-title":"Enzymatic mechanism for the hydrolysis of 5,10-methenyltetrahydropteroylglutamate to 5-formyltetrahydropteroylglutamate by serine hydroxymethyltransferase","volume":"31","author":"Stover","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.envpol.2026.128041_bib54","doi-asserted-by":"crossref","first-page":"12073","DOI":"10.1080\/10408398.2022.2098249","article-title":"Gut firmicutes: relationship with dietary fiber and role in host homeostasis","volume":"63","author":"Sun","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.envpol.2026.128041_bib55","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2022.2156764","article-title":"Exogenous antibiotic resistance gene contributes to intestinal inflammation by modulating the gut microbiome and inflammatory cytokine responses in mouse","volume":"15","author":"Tan","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.envpol.2026.128041_bib56","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0065-2660(02)46013-0","article-title":"Antisense RNAs in bacteria and their genetic elements","volume":"46","author":"Wagner","year":"2002","journal-title":"Adv. Genet."},{"key":"10.1016\/j.envpol.2026.128041_bib57","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1146\/annurev-micro-032521-022006","article-title":"Mobile genetic element flexibility as an underlying principle to bacterial evolution","volume":"77","author":"Weisberg","year":"2023","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.envpol.2026.128041_bib58","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.advms.2021.05.003","article-title":"The role of microbiota and enteroendocrine cells in maintaining homeostasis in the human digestive tract","volume":"66","author":"Wo\u017aniak","year":"2021","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.envpol.2026.128041_bib59","doi-asserted-by":"crossref","first-page":"10524","DOI":"10.1074\/jbc.TM118.000372","article-title":"Homologous recombination and the repair of DNA double-strand breaks","volume":"293","author":"Wright","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.envpol.2026.128041_bib60","first-page":"9","article-title":"Health risk ranking of antibiotic resistance genes in environment","volume":"42","author":"Xu","year":"2025","journal-title":"Chem. Bioeng."},{"key":"10.1016\/j.envpol.2026.128041_bib61","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1038\/s41467-021-25096-3","article-title":"An omics-based framework for assessing the health risk of antimicrobial resistance genes","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2026.128041_bib62","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1038\/s41467-022-29283-8","article-title":"Assessment of global health risk of antibiotic resistance genes","volume":"13","author":"Zhang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2026.128041_bib63","article-title":"The impact of antibiotic exposure on antibiotic resistance gene dynamics in the gut microbiota of inflammatory bowel disease patients","volume":"15","author":"Zhang","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envpol.2026.128041_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116318","article-title":"Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches","volume":"186","author":"Zhao","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2026.128041_bib65","doi-asserted-by":"crossref","first-page":"7141","DOI":"10.1038\/s41467-025-61606-3","article-title":"Global soil antibiotic resistance genes are associated with increasing risk and connectivity to human resistome","volume":"16","author":"Zhao","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2026.128041_bib66","doi-asserted-by":"crossref","first-page":"14088","DOI":"10.1021\/acs.est.8b05116","article-title":"Land use influences antibiotic resistance in the microbiome of soil collembolans Orchesellides sinensis","volume":"52","author":"Zhu","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2026.128041_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117402","article-title":"Distribution of antibiotic resistance genes in the environment","volume":"285","author":"Zhuang","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.128041_bib68","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0140-6736(22)01595-1","article-title":"Advancing one human\u2013animal\u2013environment Health for global health security: what does the evidence say?","volume":"401","author":"Zinsstag","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.envpol.2026.128041_bib69","doi-asserted-by":"crossref","DOI":"10.3389\/fenvs.2023.1109298","article-title":"Grazing disturbance increased the mobility, pathogenicity and host microbial species of antibiotic resistance genes, and multidrug resistance genes posed the highest risk in the habitats of wild animals","volume":"11","author":"Zou","year":"2023","journal-title":"Front. Environ. Sci."},{"key":"10.1016\/j.envpol.2026.128041_bib70","doi-asserted-by":"crossref","first-page":"3083","DOI":"10.3390\/ani13193083","article-title":"Human disturbance increases health risks to golden snub-nosed monkeys and the transfer risk of pathogenic antibiotic-resistant bacteria from golden snub-nosed monkeys to humans","volume":"13","author":"Zou","year":"2023","journal-title":"Animals"},{"key":"10.1016\/j.envpol.2026.128041_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.117117","article-title":"Assessment of health risk of antibiotics resistance genes from human disturbed habitat to wild animals: metagenomic insights into availability and functional changes of gut microbiome","volume":"285","author":"Zou","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126004112?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126004112?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T02:51:00Z","timestamp":1776826260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749126004112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":73,"alternative-id":["S0269749126004112"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128041","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The health threat of wild animals by Rank I ARGs from habitat soils: Metagenomic and metabolomic evidence","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128041","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128041"}}