{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T15:21:07Z","timestamp":1783178467021,"version":"3.54.6"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U1804184"],"award-info":[{"award-number":["U1804184"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82073618"],"award-info":[{"award-number":["82073618"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.envpol.2026.128297","type":"journal-article","created":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T12:38:21Z","timestamp":1778243901000},"page":"128297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Enterococcus is a potential reservoir associated with antibiotic resistance in the \u201cenvironment-animal-human\u201d chain of dairy farms: Evidence from ecological linkage"],"prefix":"10.1016","volume":"401","author":[{"given":"Yanrong","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xixi","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinzhao","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6129-0310","authenticated-orcid":false,"given":"Shuaiyin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib1","article-title":"Emergence of multi-drug-resistant, vancomycin-resistant, and multi-virulent enterococcus species from chicken, dairy, and human samples in Egypt","volume":"136","author":"Abd El-Hamid","year":"2025","journal-title":"J. Appl. Microbiol."},{"issue":"2","key":"10.1016\/j.envpol.2026.128297_bib2","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.1016\/S2542-5196(23)00278-4","article-title":"The need for one health systems-thinking approaches to understand multiscale dissemination of antimicrobial resistance","volume":"8","author":"Arnold","year":"2024","journal-title":"Lancet Planet. Health"},{"key":"10.1016\/j.envpol.2026.128297_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.109009","article-title":"Overcoming China's animal waste disposal challenge brought by elevated levels of veterinary antimicrobial residues and antimicrobial resistance","volume":"191","author":"Cheng","year":"2024","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib4","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2022.2055944","article-title":"Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome","volume":"14","author":"Crits-Christoph","year":"2022","journal-title":"Gut Microbes"},{"key":"10.1016\/j.envpol.2026.128297_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150685","article-title":"Effect of cattle farm exposure on oropharyngeal and gut microbial communities and antibiotic resistance genes in workers","volume":"806","author":"Ding","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib6","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2025.2514138","article-title":"Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota","volume":"17","author":"Ding","year":"2025","journal-title":"Gut Microbes"},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib7","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1038\/s41467-022-29096-9","article-title":"Strain-level characterization of broad host range Mobile genetic elements transferring antibiotic resistance from the human microbiome","volume":"13","author":"Forster","year":"2022","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.envpol.2026.128297_bib8","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.tim.2019.12.002","article-title":"The peril and promise of integrons: beyond antibiotic resistance","volume":"28","author":"Ghaly","year":"2020","journal-title":"Trends Microbiol."},{"issue":"2","key":"10.1016\/j.envpol.2026.128297_bib9","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1128\/MMBR.00056-13","article-title":"Integrons: past, present, and future","volume":"78","author":"Gillings","year":"2014","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"10459","key":"10.1016\/j.envpol.2026.128297_bib10","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0140-6736(24)01867-1","article-title":"Global burden of bacterial antimicrobial resistance 1990-2021: a systematic analysis with forecasts to 2050","volume":"404","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.envpol.2026.128297_bib11","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/2815279","article-title":"Antimicrobial resistance and virulence genes in Enterococcus faecium and Enterococcus faecalis from humans and retail red meat","author":"Golob","year":"2019","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.envpol.2026.128297_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.116088","article-title":"Antibiotic resistomes in drinking water sources across a large geographical scale: multiple drivers and co-occurrence with opportunistic bacterial pathogens","volume":"183","author":"Han","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.envpol.2026.128297_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2022.105745","article-title":"Analysis of virulence genes, drug resistance detection, and pathogenicity in enterococcus from farm animals","volume":"171","author":"Kang","year":"2022","journal-title":"Microb. Pathog."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib14","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s12941-024-00722-2","article-title":"Fitness costs of Tn1546-type transposons harboring the vanA operon by plasmid type and structural diversity in Enterococcus faecium","volume":"23","author":"Kim","year":"2024","journal-title":"Ann. Clin. Microbiol. Antimicrob."},{"issue":"5","key":"10.1016\/j.envpol.2026.128297_bib15","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.mib.2006.07.001","article-title":"Identification of high-risk enterococcal clonal complexes: global dispersion and antibiotic resistance","volume":"9","author":"Leavis","year":"2006","journal-title":"Curr. Opin. Microbiol."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/s41396-022-01315-7","article-title":"Dissecting microbial communities and resistomes for interconnected humans, soil, and livestock","volume":"17","author":"Maciel-Guerra","year":"2023","journal-title":"ISME J."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib18","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1186\/s12866-024-03491-2","article-title":"Linezolid-resistant Enterococcus faecium clinical isolates from Pakistan: a genomic analysis","volume":"24","author":"Nasir","year":"2024","journal-title":"BMC Microbiol."},{"issue":"10442","key":"10.1016\/j.envpol.2026.128297_bib19","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1016\/S0140-6736(24)00876-6","article-title":"The scope of the antimicrobial resistance challenge","volume":"403","author":"Okeke","year":"2024","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.envpol.2026.128297_bib20","doi-asserted-by":"crossref","first-page":"4870","DOI":"10.1021\/acs.est.2c09739","article-title":"Uncovering bacterial hosts of class 1 integrons in an urban coastal aquatic environment with a single-cell fusion-polymerase chain reaction technology","volume":"57","author":"Qi","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"4","key":"10.1016\/j.envpol.2026.128297_bib21","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00007-19","article-title":"Transferable mechanisms of quinolone resistance from 1998 onward","volume":"32","author":"Ruiz","year":"2019","journal-title":"Clin. Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib22","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s12866-019-1539-y","article-title":"Antimicrobial resistance pattern, virulence determinants and molecular analysis of Enterococcus faecium isolated from children infections in Iran","volume":"19","author":"Sattari-Maraji","year":"2019","journal-title":"BMC Microbiol."},{"issue":"5","key":"10.1016\/j.envpol.2026.128297_bib23","doi-asserted-by":"crossref","first-page":"634","DOI":"10.4161\/viru.28998","article-title":"Correlation between biofilm formation and gelE, esp, and agg genes in enterococcus spp. clinical isolates","volume":"5","author":"Soares","year":"2014","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib24","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1038\/s41467-020-15222-y","article-title":"Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms","volume":"11","author":"Sun","year":"2020","journal-title":"Nat. Commun."},{"issue":"10442","key":"10.1016\/j.envpol.2026.128297_bib25","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1016\/S0140-6736(24)01076-6","article-title":"Antimicrobial resistance: an agenda for all","volume":"403","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.envpol.2026.128297_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109653","article-title":"MGE-Associated ARGs exhibit higher expression efficiency than chromosomal non-MGE loci and predominantly contribute to resistance expression in pig farm wastewater","volume":"202","author":"Wan","year":"2025","journal-title":"Environ. Int."},{"issue":"5","key":"10.1016\/j.envpol.2026.128297_bib27","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1128\/AAC.01400-08","article-title":"New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis","volume":"53","author":"Wang","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"issue":"6","key":"10.1016\/j.envpol.2026.128297_bib28","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02080-23","article-title":"Genomic analysis of almost 8,000 salmonella genomes reveals drivers and landscape of antimicrobial resistance in China","volume":"11","author":"Wang","year":"2023","journal-title":"Microbiol. Spectr."},{"issue":"12","key":"10.1016\/j.envpol.2026.128297_bib29","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1128\/JB.185.12.3613-3623.2003","article-title":"Role of the Enterococcus faecalis GelE protease in determination of cellular chain length, supernatant pheromone levels, and degradation of fibrin and misfolded surface proteins","volume":"185","author":"Waters","year":"2003","journal-title":"J. Bacteriol."},{"issue":"6","key":"10.1016\/j.envpol.2026.128297_bib30","doi-asserted-by":"crossref","first-page":"821","DOI":"10.3201\/eid1106.041204","article-title":"Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex","volume":"11","author":"Willems","year":"2005","journal-title":"Emerg. Infect. Dis."},{"issue":"4","key":"10.1016\/j.envpol.2026.128297_bib31","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00151-12","article-title":"Restricted gene flow among hospital subpopulations of Enterococcus faecium","volume":"3","author":"Willems","year":"2012","journal-title":"mBio"},{"key":"10.1016\/j.envpol.2026.128297_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.136226","article-title":"Airborne antibiotics, antimicrobial resistance, and bacterial pathogens in a commercial composting facility: transmission and exposure risk","volume":"480","author":"Xin","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envpol.2026.128297_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112687","article-title":"Revealing the distribution characteristics of antibiotic resistance genes and bacterial communities in animal-aerosol-human in a chicken farm: from one-health perspective","volume":"224","author":"Yang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2026.128297_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejsobi.2020.103269","article-title":"Contribution of environmental factors on the distribution of antibiotic resistance genes in agricultural soil","volume":"102","author":"Yang","year":"2021","journal-title":"Eur. J. Soil Biol."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib35","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3168\/jds.2018-14576","article-title":"Short communication: antimicrobial resistance and virulence genes of Enterococcus faecalis isolated from subclinical bovine mastitis cases in China","volume":"102","author":"Yang","year":"2019","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.envpol.2026.128297_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.119875","article-title":"Global environmental resistome: distinction and connectivity across diverse habitats benchmarked by metagenomic analyses","volume":"235","author":"Yin","year":"2023","journal-title":"Water Res."},{"issue":"8","key":"10.1016\/j.envpol.2026.128297_bib37","doi-asserted-by":"crossref","first-page":"4469","DOI":"10.1128\/AEM.71.8.4469-4477.2005","article-title":"Identification and characterization of putative virulence genes and gene clusters in Aeromonas hydrophila PPD134\/91","volume":"71","author":"Yu","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envpol.2026.128297_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.104986","article-title":"Redistribution of intracellular and extracellular free & adsorbed antibiotic resistance genes through a wastewater treatment plant by an enhanced extracellular DNA extraction method with magnetic beads","volume":"131","author":"Yuan","year":"2019","journal-title":"Environ. Int."},{"issue":"23","key":"10.1016\/j.envpol.2026.128297_bib39","doi-asserted-by":"crossref","DOI":"10.1128\/aem.01551-22","article-title":"Role of the fsr quorum-sensing system in Enterococcus faecalis bloodstream infection","volume":"88","author":"Yue","year":"2022","journal-title":"Appl. Environ. Microbiol."},{"issue":"7","key":"10.1016\/j.envpol.2026.128297_bib40","doi-asserted-by":"crossref","DOI":"10.3390\/foods11070975","article-title":"Linezolid-resistant enterococcus spp. isolates from foods of animal origin-the genetic basis of acquired resistance","volume":"11","author":"Zarzecka","year":"2022","journal-title":"Foods"},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib41","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1021\/acs.est.7b04283","article-title":"Cell-free DNA: a neglected source for antibiotic resistance genes spreading from WWTPs","volume":"52","author":"Zhang","year":"2018","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envpol.2026.128297_bib42","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2024.2352435","article-title":"Streptococcus suis serotype 4: a population with the potential pathogenicity in humans and pigs","volume":"13","author":"Zhu","year":"2024","journal-title":"Emerg. Microb. Infect."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126006676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126006676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T15:12:38Z","timestamp":1783177958000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749126006676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":41,"alternative-id":["S0269749126006676"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128297","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enterococcus is a potential reservoir associated with antibiotic resistance in the \u201cenvironment-animal-human\u201d chain of dairy farms: Evidence from ecological linkage","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128297","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128297"}}