{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:48:56Z","timestamp":1785876536513,"version":"3.56.0"},"reference-count":97,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:00:00Z","timestamp":1781308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013209","name":"Hellenic Foundation for Research and Innovation","doi-asserted-by":"publisher","award":["11040"],"award-info":[{"award-number":["11040"]}],"id":[{"id":"10.13039\/501100013209","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.envpol.2026.128583","type":"journal-article","created":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T17:53:09Z","timestamp":1781459589000},"page":"128583","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Investigating the effects of disposable face masks leaching compounds on marine biota: a toxicogenomic approach using stress indices and transcriptomics in tissues of mussel Mytilus galloprovincialis"],"prefix":"10.1016","volume":"405","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2890-5206","authenticated-orcid":false,"given":"Georgios","family":"Kalamaras","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3939-9286","authenticated-orcid":false,"given":"Nikolina","family":"Charalampous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4156-2419","authenticated-orcid":false,"given":"Stefanos","family":"Dailianis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7960-7598","authenticated-orcid":false,"given":"Maria","family":"Kamilari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2026.128583_bib1","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.envpol.2026.128583_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2020.111517","article-title":"Surgical face masks as a potential source for microplastic pollution in the COVID-19 scenario","volume":"159","author":"Aragaw","year":"2020","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2026.128583_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2020.105017","article-title":"Impact of nanoplastics on hemolymph immune parameters and microbiota composition in Mytilus galloprovincialis","volume":"159","author":"Auguste","year":"2020","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.envpol.2026.128583_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.618726","article-title":"Immunological responses of marine bivalves to contaminant exposure: contribution of the -Omics approach","volume":"12","author":"Balbi","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib5","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/nrm3629","article-title":"Control of cell cycle transcription during G1 and S phases","volume":"14","author":"Bertoli","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envpol.2026.128583_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154603","article-title":"Differentiation in the expression of toxic effects of polyethylene-microplastics on two freshwater fish species: size matters","volume":"830","author":"Bobori","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib7","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/s41592-021-01101-x","article-title":"Sensitive protein alignments at tree-of-life scale using DIAMOND","volume":"18","author":"Buchfink","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.envpol.2026.128583_bib8","doi-asserted-by":"crossref","first-page":"127","DOI":"10.3354\/dao029127","article-title":"Hemolymph cell types of the mussel Mytilus galloprovincialis","volume":"29","author":"Carballal","year":"1997","journal-title":"Dis. Aquat. Organ."},{"issue":"19","key":"10.1016\/j.envpol.2026.128583_bib9","article-title":"The release potential of microplastics from face masks into the aquatic environment","volume":"15","author":"Celik","year":"2023","journal-title":"Sustain. Times"},{"key":"10.1016\/j.envpol.2026.128583_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132093","article-title":"Phthalate acid esters contribute to the cytotoxicity of mask leachate: cell-based assay for toxicity assessment","volume":"459","author":"Chang","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2026.128583_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2025.119123","article-title":"Transcriptomics and stress indices reveal Tetraglyme-mediated adverse effects in the Mediterranean mussel Mytilus galloprovincialis","volume":"304","author":"Charalampous","year":"2025","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2026.128583_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142884","article-title":"Toxic effect of mussel Mytilus galloprovincialis exposed to Ag\u2013TiO2 and ZnTi2O4\u2013TiO2 bicomponent nanoparticles","volume":"363","author":"Chelebieva","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2026.128583_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2025.127136","article-title":"Beyond carrier effects: polyamide microplastics and TCPP jointly drive physiological toxicity in mussels at environmental concentrations","volume":"385","author":"Chen","year":"2025","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.128583_bib14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.dci.2016.02.027","article-title":"A novel ubiquitin-protein ligase E3 functions as a modulator of immune response against lipopolysaccharide in Pacific oyster, Crassostrea gigas","volume":"60","author":"Cheng","year":"2016","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.134317","article-title":"Long-term exposure of the Mediterranean mussels, Mytilus galloprovincialis to polyethylene terephthalate microfibers: implication for reproductive and neurotoxic effects","volume":"299","author":"Choi","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2026.128583_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2021.112419","article-title":"Estimating marine plastic pollution from COVID-19 face masks in coastal regions","volume":"168","author":"Chowdhury","year":"2021","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2026.128583_bib17","doi-asserted-by":"crossref","first-page":"3674","DOI":"10.1093\/bioinformatics\/bti610","article-title":"Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research","volume":"21","author":"Conesa","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.envpol.2026.128583_bib18","article-title":"Review: mytilus galloprovincialis: an essential, low-cost model organism for the impact of xenobiotics on oxidative stress and public health","volume":"256","author":"Curpan","year":"2022","journal-title":"Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2026.128583_bib19","first-page":"43","article-title":"Environmental impact of anthropogenic activities: the use of mussels as a reliable tool for monitoring marine pollution","author":"Dailianis","year":"2011","journal-title":"Mussels Anat. Habitat Environ. Impact"},{"key":"10.1016\/j.envpol.2026.128583_bib20","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.fsi.2009.06.016","article-title":"Production of superoxides and nitric oxide generation in haemocytes of mussel Mytilus galloprovincialis (Lmk.) after exposure to cadmium: a possible involvement of Na+\/H+ exchanger in the induction of cadmium toxic effects","volume":"27","author":"Dailianis","year":"2009","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.170616","article-title":"New insights into the size-independent bioactive potential of pristine and UV-B aged polyethylene microplastics","volume":"918","author":"Dailianis","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165902","article-title":"Different isoforms of parabens into marine environment: biological effects on the bacterium Aliivibrio fischeri and the marine mussel Mytilus galloprovincialis","volume":"900","author":"Dailianis","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.826255","article-title":"Bivalve haemocyte subpopulations: a review","volume":"13","author":"de la Ballina","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib24","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.fsi.2018.09.018","article-title":"Single and repetitive microplastics exposures induce immune system modulation and homeostasis alteration in the edible mussel Mytilus galloprovincialis","volume":"83","author":"D\u00e9tr\u00e9e","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119258","article-title":"Leaching of microplastic-associated additives in aquatic environments: a critical review","volume":"305","author":"Do","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.128583_bib26","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1038\/cdd.2012.36","article-title":"Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability","volume":"19","author":"Dorstyn","year":"2012","journal-title":"Cell Death Differ."},{"issue":"3","key":"10.1016\/j.envpol.2026.128583_bib27","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/etc.5494","article-title":"Transcriptional responses as biomarkers of general toxicity: a systematic review and meta\u2010analysis on metal\u2010exposed bivalves","volume":"42","author":"Ekelund Ugge","year":"2023","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envpol.2026.128583_bib28","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2174\/1568026013394831","article-title":"Toxic metals and oxidative stress Part I: mechanisms involved in metal induced oxidative damage","volume":"1","author":"Ercal","year":"2001","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.envpol.2026.128583_bib29","year":"2022"},{"key":"10.1016\/j.envpol.2026.128583_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140279","article-title":"Covid-19 face masks: a potential source of microplastic fibers in the environment","volume":"737","author":"Fadare","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib31","doi-asserted-by":"crossref","DOI":"10.20517\/wecn.2023.57","article-title":"Impact of face masks weathering on the mussels Mytilus galloprovincialis","volume":"3","author":"Fonseca","year":"2023","journal-title":"Water Emerg. Contam. Nanoplastics"},{"key":"10.1016\/j.envpol.2026.128583_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2025.121732","article-title":"Revealing the effects of polystyrene microplastics and di(2-ethylhexyl) phthalate on mussels: an evidence chain of gill-intestine-hemolymph","volume":"279","author":"Gao","year":"2025","journal-title":"Environ. Res."},{"key":"10.1016\/j.envpol.2026.128583_bib34","first-page":"17","article-title":"The crustacean selenoproteome similarity to other arthropods homologs: a mini review. Electron","volume":"15","author":"Garc\u00eda-Triana","year":"2012","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.envpol.2026.128583_bib35","first-page":"182","article-title":"Generation of free radicals in haemocytes of mussels after exposure to low molecular weight PAH components: immune activation, oxidative and genotoxic effects","volume":"155","author":"Giannapas","year":"2012","journal-title":"Comp. Biochem. Physiol., Part C: Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2026.128583_bib36","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s00441-005-1093-9","article-title":"Characterization of mussel gill cells in vivo and in vitro","volume":"321","author":"G\u00f3mez-Mendikute","year":"2005","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.envpol.2026.128583_bib37","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0141-1136(02)00177-0","article-title":"Oxygen radicals production and actin filament disruption in bivalve haemocytes treated with benzo(a)pyrene","volume":"54","author":"G\u00f3mez-Mendikute","year":"2002","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.envpol.2026.128583_bib38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.aquatox.2016.05.027","article-title":"Effect of diet quality on mussel biomarker responses to pollutants","volume":"177","author":"Gonz\u00e1lez-Fern\u00e1ndez","year":"2016","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envpol.2026.128583_bib39","doi-asserted-by":"crossref","first-page":"46","DOI":"10.37828\/em.2023.63.5","article-title":"Short-time salinity fluctuations are strong activators of oxidative stress in Mediterranean mussel (Mytilus galloprovincialis)","volume":"63","author":"Gostyukhina","year":"2023","journal-title":"Ecol. Montenegrina"},{"key":"10.1016\/j.envpol.2026.128583_bib40","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0003-2697(82)90118-X","article-title":"Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids","volume":"126","author":"Green","year":"1982","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.envpol.2026.128583_bib41","doi-asserted-by":"crossref","first-page":"404","DOI":"10.3390\/d16070404","article-title":"Hemolymph parameters are a useful tool for assessing bivalve health and water quality","volume":"16","author":"Grinchenko","year":"2024","journal-title":"Diversity"},{"key":"10.1016\/j.envpol.2026.128583_bib42","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ab.2015.03.024","article-title":"An accurate and sensitive Coomassie brilliant blue G-250-based assay for protein determination","volume":"480","author":"Grintzalis","year":"2015","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.envpol.2026.128583_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.margen.2023.101060","article-title":"Size and site specific transcriptomic responses of blue mussel (Mytilus edulis) to acute hypoxia","volume":"71","author":"Hall","year":"2023","journal-title":"Mar. Genom."},{"key":"10.1016\/j.envpol.2026.128583_bib44","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tox.2011.03.001","article-title":"Advances in metal-induced oxidative stress and human disease","volume":"283","author":"Jomova","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.envpol.2026.128583_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2024.125290","article-title":"Disposable face masks into aquatic media: Chemical and biological testing of the released compounds during the leaching process","volume":"363","author":"Kalamaras","year":"2024","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envpol.2026.128583_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.124364","article-title":"Global evaluation of heavy metal content in surface water bodies: a meta-analysis using heavy metal pollution indices and multivariate statistical analyses","volume":"236","author":"Kumar","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2026.128583_bib47","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1007\/s11270-025-08112-w","article-title":"Evaluation of the toxicological effects of microparticles from disposable polypropylene face masks in Oreochromis niloticus","volume":"236","author":"Lechinovski","year":"2025","journal-title":"Water. Air. Soil Pollut."},{"key":"10.1016\/j.envpol.2026.128583_bib48","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.biori.2019.09.001","article-title":"Effects of textile dyes on health and the environment and bioremediation potential of living organisms","volume":"3","author":"Lellis","year":"2019","journal-title":"Biotechnol. Res. Innov."},{"key":"10.1016\/j.envpol.2026.128583_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.marpolbul.2025.118466","article-title":"The combined effects of aging polylactic acid microplastics and TCPP on the byssus genes of the mussel Mytilus coruscus","volume":"221","author":"Li","year":"2025","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2026.128583_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119019","article-title":"Generation of environmental persistent free radicals (EPFRs) enhances ecotoxicological effects of the disposable face mask waste with the COVID-19 pandemic","volume":"301","author":"Liu","year":"2022","journal-title":"Environ. Pollut."},{"issue":"12","key":"10.1016\/j.envpol.2026.128583_bib51","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1242\/jeb.118190","article-title":"The environmentally tuned transcriptomes of Mytilus mussels","volume":"218","author":"Lockwood","year":"2015","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.envpol.2026.128583_bib52","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.37257","article-title":"Global percentage of asymptomatic SARS-CoV-2 infections among the tested population and individuals with confirmed COVID-19 diagnosis. A systematic review and meta-analysis","volume":"4","author":"Ma","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.envpol.2026.128583_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2025.107492","article-title":"Uptake and depuration kinetics of emerging organic contaminants (EOCs) in the New Zealand green-lipped mussel (Perna canaliculus): Seafood safety implications","volume":"212","author":"Mahaliyana","year":"2025","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.envpol.2026.128583_bib54","series-title":"Current Topics in Developmental Biology","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0070-2153(07)80006-8","article-title":"Molluscan shell proteins: primary structure, origin, and evolution","author":"Marin","year":"2007"},{"key":"10.1016\/j.envpol.2026.128583_bib55","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1615\/CritRevEukaryotGeneExpr.2013006875","article-title":"Review of Poly (ADP-ribose) Polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases","volume":"24","author":"Morales","year":"2014","journal-title":"Crit. Rev. Eukaryot. Gene Expr."},{"key":"10.1016\/j.envpol.2026.128583_bib56","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00227-018-3308-0","article-title":"Bivalve transcriptomics reveal pathogen sequences and a powerful immune response of the Mediterranean mussel (Mytilus galloprovincialis)","volume":"165","author":"Moreira","year":"2018","journal-title":"Mar. Biol."},{"key":"10.1016\/j.envpol.2026.128583_bib57","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41021-024-00298-5","article-title":"CDK4\/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis","volume":"46","author":"Okada","year":"2024","journal-title":"Genes Environ"},{"key":"10.1016\/j.envpol.2026.128583_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2023.109308","article-title":"Current knowledge on the presence, biodegradation, and toxicity of discarded face masks in the environment","volume":"11","author":"Oliveira","year":"2023","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.envpol.2026.128583_bib59","doi-asserted-by":"crossref","DOI":"10.3390\/fishes10070339","article-title":"Molecular mechanisms and biomarker-based early-warning indicators of heavy metal toxicity in marine fish","volume":"10","author":"Oros","year":"2025","journal-title":"Fishes"},{"issue":"D1","key":"10.1016\/j.envpol.2026.128583_bib60","first-page":"D77","article-title":"Expression Atlas update: from tissues to single cells","volume":"48","author":"Papatheodorou","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.envpol.2026.128583_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.148505","article-title":"Risks of Covid-19 face masks to wildlife: present and future research needs","volume":"792","author":"Patr\u00edcio Silva","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib62","first-page":"93","article-title":"Assay for measuring immune response in the mussel Mytilus edulis","volume":"4","author":"Pipe","year":"1995","journal-title":"Tech Fish Immunol"},{"key":"10.1016\/j.envpol.2026.128583_bib63","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ecoenv.2017.10.021","article-title":"The impact of expired commercial drugs on non-target marine species: a case study with the use of a battery of biomarkers in hemocytes of mussels","volume":"148","author":"Politakis","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2026.128583_bib64","doi-asserted-by":"crossref","first-page":"7760","DOI":"10.1021\/acs.est.0c02178","article-title":"COVID-19 pandemic repercussions on the use and management of plastics","volume":"54","author":"Prata","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envpol.2026.128583_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.734242","article-title":"Gill transcriptomic analysis in fast- and slow-growing individuals of Mytilus galloprovincialis","volume":"511","author":"Prieto","year":"2019","journal-title":"Aquaculture"},{"key":"10.1016\/j.envpol.2026.128583_bib66","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0378-1119(97)00413-7","article-title":"Primary structure of an invertebrate dihydrolipoamide dehydrogenase with phylogenetic relationship to vertebrate and bacterial disulfide oxidoreductases1","volume":"200","author":"Pullikuth","year":"1997","journal-title":"Gene"},{"issue":"10","key":"10.1016\/j.envpol.2026.128583_bib67","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e30858","article-title":"Different recovery patterns of the surviving bivalve Mytilus galloprovincialis based on transcriptome profiling exposed to spherical or fibrous polyethylene microplastics","volume":"10","author":"Rangaswamy","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.envpol.2026.128583_bib68","first-page":"106","article-title":"Oxidative pathways of chemical toxicity and oxidative stress biomarkers in marine organisms","volume":"93","author":"Regoli","year":"2014","journal-title":"Mar. Environ. Res., Sensing the marine environment using different animal models and levels of complexity"},{"key":"10.1016\/j.envpol.2026.128583_bib69","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1006\/taap.1999.8637","article-title":"Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals","volume":"156","author":"Regoli","year":"1999","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envpol.2026.128583_bib70","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.marpolbul.2017.06.078","article-title":"Microplastics effects in Scrobicularia plana","volume":"122","author":"Ribeiro","year":"2017","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envpol.2026.128583_bib71","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2022.861557","article-title":"Aged plastic leaching of dissolved organic matter is two orders of magnitude higher than virgin plastic leading to a strong uplift in marine microbial activity","volume":"9","author":"Romera-Castillo","year":"2022","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.envpol.2026.128583_bib72","doi-asserted-by":"crossref","first-page":"727","DOI":"10.2983\/035.037.0405","article-title":"Selective capture and ingestion of particles by suspension-feeding bivalve molluscs: a Review","volume":"37","author":"Rosa","year":"2018","journal-title":"J. Shellfish Res."},{"key":"10.1016\/j.envpol.2026.128583_bib73","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.615580","article-title":"Transcriptomic response of mussel gills after a Vibrio splendidus infection demonstrates their role in the immune response","volume":"11","author":"Saco","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib74","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-65596-8","article-title":"Immunotoxicity of polystyrene nanoplastics in different hemocyte subpopulations of Mytilus galloprovincialis","volume":"10","author":"Sendra","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2026.128583_bib75","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.128186","article-title":"Surgical face masks as a source of emergent pollutants in aquatic systems: analysis of their degradation product effects in Danio rerio through RNA-Seq","volume":"428","author":"Sendra","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2026.128583_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142024","article-title":"An overview of the internalization and effects of microplastics and nanoplastics as pollutants of emerging concern in bivalves","volume":"753","author":"Sendra","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envpol.2026.128583_bib77","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/icb\/ict028","article-title":"Energy-limited tolerance to stress as a conceptual framework to integrate the effects of multiple stressors","volume":"53","author":"Sokolova","year":"2013","journal-title":"Integr. Comp. Biol."},{"key":"10.1016\/j.envpol.2026.128583_bib78","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0891-5849(94)00159-H","article-title":"Oxidative mechanisms in the toxicity of metal ions","volume":"18","author":"Stohs","year":"1995","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.envpol.2026.128583_bib79","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1038\/ni0503-404","article-title":"The death effector domain protein family: regulators of cellular homeostasis","volume":"4","author":"Tibbetts","year":"2003","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.envpol.2026.128583_bib98","series-title":"Manual on The Biomarkers Recommended for The MED POL Biomonitoring Programme","year":"1999"},{"key":"10.1016\/j.envpol.2026.128583_bib80","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2174\/0929867053764635","article-title":"Metals, toxicity and oxidative stress","volume":"12","author":"Valko","year":"2005","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.envpol.2026.128583_bib81","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0378-1119(03)00708-X","article-title":"Towards a catalogue of genes transcribed in multiple tissues of Mytilus galloprovincialis","volume":"314","author":"Venier","year":"2003","journal-title":"Gene"},{"key":"10.1016\/j.envpol.2026.128583_bib82","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.3390\/cells9051259","article-title":"The role of caspase-2 in regulating cell fate","volume":"9","author":"Vigneswara","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.envpol.2026.128583_bib83","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/02757540701653285","article-title":"Heavy-metal effects on lipid peroxidation and antioxidant defence enzymes in mussels Mytilus galloprovincialis","volume":"23","author":"Vlahogianni","year":"2007","journal-title":"Chem. Ecol."},{"key":"10.1016\/j.envpol.2026.128583_bib84","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/toxics10010018","article-title":"Accumulation, depuration, and biological effects of polystyrene microplastic spheres and adsorbed cadmium and benzo(a)pyrene on the mussel Mytilus galloprovincialis","volume":"10","author":"von Hellfeld","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.envpol.2026.128583_bib85","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s12064-012-0162-3","article-title":"Measurement of mRNA abundance using RNA-seq data: RPKM measure is inconsistent among samples","volume":"131","author":"Wagner","year":"2012","journal-title":"Theory Biosci. Theor. Den Biowissenschaften"},{"key":"10.1016\/j.envpol.2026.128583_bib86","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1042\/bj1130315","article-title":"Lipid peroxide formation in microsomes","volume":"113","author":"Wills","year":"1969","journal-title":"Biochem. J."},{"key":"10.1016\/j.envpol.2026.128583_bib87","article-title":"Airborne transmission of COVID-19","volume":"370","author":"Wilson","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.envpol.2026.128583_bib88","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1186\/s12864-021-08233-6","article-title":"The expanded inhibitor of apoptosis gene family in oysters possesses novel domain architectures and may play diverse roles in apoptosis following immune challenge","volume":"23","author":"Witkop","year":"2022","journal-title":"BMC Genom."},{"key":"10.1016\/j.envpol.2026.128583_bib89","doi-asserted-by":"crossref","DOI":"10.3389\/fmars.2021.658361","article-title":"Dose-dependent effects of di-(2-ethylhexyl) phthalate (DEHP) in mussel Mytilus galloprovincialis","volume":"8","author":"Xu","year":"2021","journal-title":"Front. Mar. Sci."},{"key":"10.1016\/j.envpol.2026.128583_bib90","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.136150","article-title":"Bioaccumulation of 35 metal(loid)s in organs of a freshwater mussel (Hyriopsis cumingii) and environmental implications in Poyang Lake, China","volume":"307","author":"Xu","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2026.128583_bib91","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s12601-015-0006-4","article-title":"Morphology and Immune-related activities of hemocytes of the mussel Mytilus coruscus (Gould, 1861) from East Sea of Korea","volume":"50","author":"Yang","year":"2015","journal-title":"Ocean Sci. J."},{"key":"10.1016\/j.envpol.2026.128583_bib92","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1042\/BST20130073","article-title":"The alternative oxidases: simple oxidoreductase proteins with complex functions","volume":"41","author":"Young","year":"2013","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.envpol.2026.128583_bib93","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nature11413","article-title":"The oyster genome reveals stress adaptation and complexity of shell formation","volume":"490","author":"Zhang","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.envpol.2026.128583_bib94","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.117235","article-title":"Effects of microplastics on dissipation of oxytetracycline and its relevant resistance genes in soil without and with Serratia marcescens: Comparison between biodegradable and conventional microplastics","volume":"287","author":"Zhang","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"24","key":"10.1016\/j.envpol.2026.128583_bib95","doi-asserted-by":"crossref","first-page":"66102","DOI":"10.1007\/s11356-023-27116-9","article-title":"Different weathering conditions affect the release of microplastics by masks","volume":"30","author":"Zhang","year":"2023","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.envpol.2026.128583_bib96","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.etap.2010.03.008","article-title":"Biomarker responses in the bivalve (Chlamys farreri) to exposure of the environmentally relevant concentrations of lead, mercury, copper","volume":"30","author":"Zhang","year":"2010","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.envpol.2026.128583_bib97","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.1016\/j.pec.2020.12.020","article-title":"Characterizing Wuhan residents' mask-wearing intention at early stages of the COVID-19 pandemic","volume":"104","author":"Zhou","year":"2021","journal-title":"Patient Educ. Couns."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026974912600953X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S026974912600953X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T20:15:19Z","timestamp":1785874519000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S026974912600953X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":97,"alternative-id":["S026974912600953X"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128583","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Investigating the effects of disposable face masks leaching compounds on marine biota: a toxicogenomic approach using stress indices and transcriptomics in tissues of mussel Mytilus galloprovincialis","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128583","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"128583"}}