{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:01:18Z","timestamp":1790424078216,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972754"],"award-info":[{"award-number":["31972754"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Pollution"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.envpol.2026.128867","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T15:41:29Z","timestamp":1785512489000},"page":"128867","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Crosstalk between gut microbiota dysbiosis and mercury-induced hepatointestinal toxicity in mice"],"prefix":"10.1016","volume":"408","author":[{"given":"Siyu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biqi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanjun","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruifeng","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4974-5850","authenticated-orcid":false,"given":"Zhigang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envpol.2026.128867_bib1","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1119227","article-title":"Acute-serum amyloid A and A-SAA-derived peptides as formyl peptide receptor (FPR) 2 ligands","volume":"14","author":"Abouelasrar Salama","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.envpol.2026.128867_bib2","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.jhep.2022.02.021","article-title":"Development and validation of a model to predict incident chronic liver disease in the general population: the CLivD score","volume":"77","author":"\u00c5berg","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.envpol.2026.128867_bib3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1146\/annurev-pathol-052016-100322","article-title":"The role of Cancer-associated fibroblasts and fibrosis in liver cancer","volume":"12","author":"Affo","year":"2017","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.envpol.2026.128867_bib4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1289\/EHP360","article-title":"Sex-dependent effects of cadmium exposure in early life on gut microbiota and fat accumulation in mice","volume":"125","author":"Ba","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envpol.2026.128867_bib5","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.stem.2022.04.008","article-title":"The spatiotemporal program of zonal liver regeneration following acute injury","volume":"29","author":"Ben-Moshe","year":"2022","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.envpol.2026.128867_bib6","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3390\/nu12010197","article-title":"The molecular and physiological effects of protein-derived polyamines in the intestine","volume":"12","author":"Bekebrede","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.envpol.2026.128867_bib7","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1053\/j.gastro.2020.04.077","article-title":"Contribution of the intestinal microbiome and gut barrier to hepatic disorders","volume":"159","author":"Chopyk","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.envpol.2026.128867_bib8","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1053\/gast.2000.19267","article-title":"Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis","volume":"119","author":"Cope","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.envpol.2026.128867_bib9","doi-asserted-by":"crossref","first-page":"4349","DOI":"10.1038\/onc.2017.7","article-title":"JNKs function as CDK4-activating kinases by phosphorylating CDK4 and p21","volume":"36","author":"Colleoni","year":"2017","journal-title":"Oncogene"},{"key":"10.1016\/j.envpol.2026.128867_bib10","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s41579-022-00805-x","article-title":"Bile acids and the gut microbiota: metabolic interactions and impacts on disease","volume":"21","author":"Collins","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envpol.2026.128867_bib11","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.2174\/0929867323666160418114600","article-title":"Structure and expression of different serum amyloid A (SAA) variants and their concentration-dependent functions during host insults","volume":"23","author":"De Buck","year":"2016","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.envpol.2026.128867_bib12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cytogfr.2015.12.010","article-title":"The cytokine-serum amyloid A-chemokine network. Cytokine","volume":"30","author":"De Buck","year":"2016","journal-title":"Growth Factor Rev."},{"key":"10.1016\/j.envpol.2026.128867_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2021.105879","article-title":"GADD45\u03b2 stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation","volume":"173","author":"Dong","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.envpol.2026.128867_bib14","article-title":"Saturated fatty acid-enriched small extracellular vesicles mediate a crosstalk inducing liver inflammation and hepatocyte insulin resistance","volume":"5","author":"Garcia-Martinez","year":"2023","journal-title":"JHEP Rep."},{"key":"10.1016\/j.envpol.2026.128867_bib16","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/nrendo.2015.40","article-title":"Gut microbiota: firmicutes and Bacteroidetes involved in insulin resistance by mediating levels of glucagon-like peptide 1","volume":"11","author":"Greenhill","year":"2015","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.envpol.2026.128867_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.130082","article-title":"Effects of thiacloprid exposure on microbiota-gut-liver axis: multiomics mechanistic analysis in Japanese quails","volume":"442","author":"Han","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2026.128867_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125984","article-title":"Pulmonary inflammatory and fibrogenic response induced by graphitized multi-walled carbon nanotube involved in cGAS-STING signaling pathway","volume":"417","author":"Han","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envpol.2026.128867_bib19","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1111\/mmi.14905","article-title":"Molecular interactions between the intestinal microbiota and the host","volume":"117","author":"Hertli","year":"2022","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.envpol.2026.128867_bib20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.cell.2019.05.041","article-title":"Patterns of early p21 dynamics determine proliferation-senescence cell fate after chemotherapy","volume":"178","author":"Hsu","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.envpol.2026.128867_bib21","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1423-0127-18-11","article-title":"Role of taurine on acid secretion in the rat stomach","volume":"18","author":"Huang","year":"2011","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.envpol.2026.128867_bib22","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1016\/j.chom.2023.07.008","article-title":"Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity","volume":"31","author":"Jordan","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.envpol.2026.128867_bib23","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.jhep.2013.01.003","article-title":"Modulation of the fecal bile acid profile by gut microbiota in cirrhosis","volume":"58","author":"Kakiyama","year":"2013","journal-title":"J. Hepatol."},{"key":"10.1016\/j.envpol.2026.128867_bib25","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a022293","article-title":"TGF-\u03b21 signaling and tissue fibrosis","volume":"10","author":"Kim","year":"2018","journal-title":"Cold Spring Harbor Perspect. Biol."},{"key":"10.1016\/j.envpol.2026.128867_bib26","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/medsci6030079","article-title":"Gut-liver axis: how do gut bacteria influence the liver?","volume":"6","author":"Konturek","year":"2018","journal-title":"Med. Sci."},{"key":"10.1016\/j.envpol.2026.128867_bib27","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1017\/S0967199417000120","article-title":"Physiological importance of polyamines","volume":"25","author":"Lenis","year":"2017","journal-title":"Zygote"},{"key":"10.1016\/j.envpol.2026.128867_bib28","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/5175581","article-title":"Downregulation of CYP39A1 serves as a novel biomarker in hepatocellular carcinoma with worse clinical outcome","volume":"2021","author":"Li","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.envpol.2026.128867_bib29","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.chemosphere.2019.06.096","article-title":"Exploring the kidney hazard of exposure to mercuric chloride in mice: disorder of mitochondrial dynamics induces oxidative stress and results in apoptosis","volume":"234","author":"Li","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.envpol.2026.128867_bib30","doi-asserted-by":"crossref","first-page":"15985","DOI":"10.1021\/acs.jafc.4c02349","article-title":"Resveratrol alleviates liver fibrosis induced by long-term inorganic Mercury exposure through activating the Sirt1\/PGC-1\u03b1 signaling pathway","volume":"72","author":"Li","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.envpol.2026.128867_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111501","article-title":"Exploring the liver fibrosis induced by deltamethrin exposure in quails and elucidating the protective mechanism of resveratrol","volume":"207","author":"Li","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2026.128867_bib32","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.enceco.2025.12.021","article-title":"Polystyrene microplastics modulation of hexavalent chromium toxicity in quails: transcriptomic and toxicological insights","volume":"8","author":"Liu","year":"2026","journal-title":"Environ. Chem. Ecotoxicol."},{"key":"10.1016\/j.envpol.2026.128867_bib33","doi-asserted-by":"crossref","first-page":"739","DOI":"10.3748\/wjg.v8.i4.739","article-title":"Effects of the tyrosine protein kinase inhibitor genistein on the proliferation, activation of cultured rat hepatic stellate cells","volume":"8","author":"Liu","year":"2002","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.envpol.2026.128867_bib34","doi-asserted-by":"crossref","first-page":"5075","DOI":"10.1007\/s00204-025-04178-x","article-title":"Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypes","volume":"99","author":"L\u00f3pez-Pascual","year":"2025","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.envpol.2026.128867_bib35","doi-asserted-by":"crossref","first-page":"7365","DOI":"10.1007\/s10661-011-2505-9","article-title":"Influence of Mercury from fly ash on cattle reared nearby thermal power plant","volume":"184","author":"Mahajan","year":"2012","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.envpol.2026.128867_bib36","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1348-0421.2007.tb03887.x","article-title":"The relationship between microbiota and polyamine concentration in the human intestine: a pilot study","volume":"51","author":"Matsumoto","year":"2007","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.envpol.2026.128867_bib37","doi-asserted-by":"crossref","first-page":"6911","DOI":"10.3748\/wjg.v19.i40.6911","article-title":"Effects of probiotics on nonalcoholic fatty liver disease: a meta-analysis","volume":"19","author":"Ma","year":"2013","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.envpol.2026.128867_bib38","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1038\/ncomms3823","article-title":"Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology","volume":"4","author":"Mederacke","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envpol.2026.128867_bib39","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1038\/s41591-022-02016-6","article-title":"Microbiome-derived ethanol in nonalcoholic fatty liver disease","volume":"28","author":"Meijnikman","year":"2022","journal-title":"Nat. Med."},{"key":"10.1016\/j.envpol.2026.128867_bib40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.arr.2011.09.003","article-title":"Gadd45 proteins: relevance to aging, longevity and age-related pathologies","volume":"11","author":"Moskalev","year":"2012","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.envpol.2026.128867_bib41","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/S2468-1253(16)30108-X","article-title":"A microbiota-centric view of diseases of the upper gastrointestinal tract","volume":"2","author":"Nardone","year":"2017","journal-title":"Lancet Gastroenterol. Hepatol."},{"key":"10.1016\/j.envpol.2026.128867_bib42","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s13280-017-1004-9","article-title":"A review of global environmental Mercury processes in response to human and natural perturbations: changes of emissions, climate, and land use","volume":"47","author":"Obrist","year":"2018","journal-title":"Ambio"},{"key":"10.1016\/j.envpol.2026.128867_bib43","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/s41575-018-0089-3","article-title":"Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators","volume":"16","author":"Piccinin","year":"2019","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.envpol.2026.128867_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-29927-x","article-title":"Health risk assessment of heavy metals in imported frozen bovine meat and organs marketed in Sohag, Egypt","author":"Rabeey","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envpol.2026.128867_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2024.102045","article-title":"Protein kinase D2 modulates hepatic insulin sensitivity in male mice","volume":"90","author":"Rada","year":"2024","journal-title":"Mol. Metabol."},{"key":"10.1016\/j.envpol.2026.128867_bib46","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1053\/j.gastro.2020.06.038","article-title":"IL1B increases intestinal tight junction permeability by up-regulation of MIR200C-3p, which degrades occludin mRNA","volume":"159","author":"Rawat","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.envpol.2026.128867_bib47","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/1452696","article-title":"PGC-1\u03b1, inflammation, and oxidative stress: an integrative view in metabolism","volume":"2020","author":"Rius-P\u00e9rez","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.envpol.2026.128867_bib48","doi-asserted-by":"crossref","DOI":"10.1007\/s00204-025-04241-7","article-title":"3,3'-Dichlorobiphenyl (PCB 11) alters the hepatic expression of cytochrome P450 enzymes in the liver of mouse dams exposed orally during pregnancy and lactation","author":"Roach","year":"2026","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.envpol.2026.128867_bib49","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1002\/jcp.22598","article-title":"Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-\u03b2-induced inhibition of hepatic stellate cell proliferation","volume":"226","author":"Sekiya","year":"2011","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.envpol.2026.128867_bib50","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1177\/0748233720970437","article-title":"Blood Mercury and liver enzymes: a pan-India retrospective correlation study","volume":"36","author":"Sivapandi","year":"2020","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.envpol.2026.128867_bib51","doi-asserted-by":"crossref","first-page":"7853","DOI":"10.1007\/s11356-021-16215-0","article-title":"Mercury accumulation in muscle and liver tissue and human health risk assessment of two resident freshwater fish species in Flanders (Belgium): a multilocation approach","volume":"29","author":"Teunen","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envpol.2026.128867_bib52","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fnut.2019.00016","article-title":"Polyamines and gut microbiota","volume":"6","author":"Tofalo","year":"2019","journal-title":"Front. Nutr."},{"key":"10.1016\/j.envpol.2026.128867_bib53","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1016\/j.clnu.2021.01.031","article-title":"Fecal g. Streptococcus and g. Eubacterium_coprostanoligenes_group combined with sphingosine to modulate the serum dyslipidemia in high-fat diet mice","volume":"40","author":"Wei","year":"2021","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.envpol.2026.128867_bib54","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1002\/ptr.7086","article-title":"Geniposide suppresses liver injury in a mouse model of DDC-induced sclerosing cholangitis","volume":"35","author":"Wen","year":"2021","journal-title":"Phytother Res."},{"key":"10.1016\/j.envpol.2026.128867_bib55","doi-asserted-by":"crossref","first-page":"5626","DOI":"10.1039\/D1FO04004A","article-title":"Konjac oligosaccharides attenuate DSS-induced ulcerative colitis in mice: mechanistic insights","volume":"13","author":"Xia","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.envpol.2026.128867_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114901","article-title":"Combination of glycyrrhizic acid and compound probiotics alleviates deoxynivalenol-induced damage to weaned piglets","volume":"256","author":"Xu","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envpol.2026.128867_bib57","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00109-016-1474-4","article-title":"Interaction between gut microbiota and toll-like receptor: from immunity to metabolism","volume":"95","author":"Yiu","year":"2017","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.envpol.2026.128867_bib58","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.cmet.2019.08.018","article-title":"Fatty liver disease caused by high-alcohol-producing Klebsiella pneumoniae","volume":"30","author":"Yuan","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.envpol.2026.128867_bib59","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2022.1092353","article-title":"Chronic liver diseases and erectile dysfunction","volume":"10","author":"Zang","year":"2023","journal-title":"Front. Public Health"},{"key":"10.1016\/j.envpol.2026.128867_bib60","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.3168\/jds.2022-22021","article-title":"Liver fibrosis is a common pathological change in the liver of dairy cows with fatty liver","volume":"106","author":"Zhang","year":"2023","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.envpol.2026.128867_bib61","doi-asserted-by":"crossref","first-page":"9252","DOI":"10.1039\/D0FO01223H","article-title":"Inflammation response after the cessation of chronic arsenic exposure and post-treatment of natural astaxanthin in liver: potential role of cytokine-mediated cell-cell interactions","volume":"11","author":"Zhang","year":"2020","journal-title":"Food Funct."},{"key":"10.1016\/j.envpol.2026.128867_bib62","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.3748\/wjg.v25.i17.2019","article-title":"Microbial metabolites in non-alcoholic fatty liver disease","volume":"25","author":"Zhou","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.envpol.2026.128867_bib63","doi-asserted-by":"crossref","first-page":"5202","DOI":"10.1038\/s41467-022-32788-x","article-title":"Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression","volume":"13","author":"Zhou","year":"2022","journal-title":"Nat. Commun."}],"container-title":["Environmental Pollution"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126012376?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0269749126012376?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:31:42Z","timestamp":1790422302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0269749126012376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":61,"alternative-id":["S0269749126012376"],"URL":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128867","relation":{},"ISSN":["0269-7491"],"issn-type":[{"value":"0269-7491","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Crosstalk between gut microbiota dysbiosis and mercury-induced hepatointestinal toxicity in mice","name":"articletitle","label":"Article Title"},{"value":"Environmental Pollution","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envpol.2026.128867","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"128867"}}