{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T10:39:38Z","timestamp":1791110378896,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.envres.2011.10.003","type":"journal-article","created":{"date-parts":[[2011,10,26]],"date-time":"2011-10-26T01:05:20Z","timestamp":1319591120000},"page":"118-125","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":128,"special_numbering":"C","title":["Prenatal exposure to perfluorinated chemicals and relationship with allergies and infectious diseases in infants"],"prefix":"10.1016","volume":"112","author":[{"given":"Emiko","family":"Okada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiko","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuaki","family":"Saijo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Washino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Miyashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumitaka","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanae","family":"Konishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichi M.","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayako","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Nakazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiko","family":"Kishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2011.10.003_bib1","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1289\/ehp.10334","article-title":"Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth","volume":"115","author":"Apelberg","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib2","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1080\/02652030500183474","article-title":"Perfluorochemicals: potential sources of and migration from food packaging","volume":"22","author":"Begley","year":"2005","journal-title":"Food Addit. Contam."},{"key":"10.1016\/j.envres.2011.10.003_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jaci.2010.07.011","article-title":"Long-term studies of the natural history of asthma in childhood","volume":"126","author":"Bisgaard","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envres.2011.10.003_bib4","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1021\/es803201a","article-title":"Perfluoroalkyl compounds (PFCs) in indoor dust: concentrations, human exposure estimates, and sources","volume":"43","author":"Bj\u00f6rklund","year":"2009","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2011.10.003_bib5","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1289\/ehp.10896","article-title":"Perfluorooctanoic acid-induced immunomodulation in adult C57BL\/6J or C57BL\/6N female mice","volume":"116","author":"Dewitt","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib6","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1080\/10408440802209804","article-title":"Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha","volume":"39","author":"Dewitt","year":"2009","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.envres.2011.10.003_bib7","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/toxsci\/kfm053","article-title":"Exposure to the immunosuppressant, perfluorooctanoic acid, enhances the murine IgE and airway hyperreactivity response to ovalbumin","volume":"97","author":"Fairley","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2011.10.003_bib8","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1289\/ehp.10506","article-title":"Perfluorinated chemicals and fetal growth: a study within the Danish National Birth Cohort","volume":"115","author":"Fei","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib9","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.envres.2010.08.004","article-title":"Prenatal exposure to PFOA and PFOS and risk of hospitalization for infectious diseases in early childhood","volume":"110","author":"Fei","year":"2010","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2011.10.003_bib10","unstructured":"Fletcher, T., Steenland, K., Savitz, D., 2009. Status Report: PFOA and Immune Biomarkers in Adults Exposed to PFOA in Drinking Water in the Mid Ohio Valley: \u3008http:\/\/www.c8sciencepanel.org\/pdfs\/Status_Report_C8_and_Immune_markers_March2009.pdf\u3009 (accessed 27 September 2011)."},{"key":"10.1016\/j.envres.2011.10.003_bib11","doi-asserted-by":"crossref","first-page":"8971","DOI":"10.1021\/es801907r","article-title":"Dietary predictors of perfluorinated chemicals: a study from the Danish National Birth Cohort","volume":"42","author":"Halldorsson","year":"2008","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2011.10.003_bib12","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1539\/joh.46.141","article-title":"The influence of time, sex and geographic factors on levels of perfluorooctane sulfonate and perfluorooctanoate in human serum over the last 25 years","volume":"46","author":"Harada","year":"2004","journal-title":"J. Occup. Health"},{"key":"10.1016\/j.envres.2011.10.003_bib13","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.chemosphere.2006.05.010","article-title":"Historical and geographical aspects of the increasing perfluorooctanoate and perfluorooctane sulfonate contamination in human serum in Japan","volume":"66","author":"Harada","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2011.10.003_bib14","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jaci.2010.07.030","article-title":"Environmental epigenetics of asthma: an update","volume":"126","author":"Ho","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envres.2011.10.003_bib15","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1289\/ehp.11064","article-title":"Biomonitoring of perfluorinated compounds in children and adults exposed to perfluorooctanoate-contaminated drinking water","volume":"116","author":"H\u00f6lzer","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib16","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1289\/ehp.6864","article-title":"Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy","volume":"112","author":"Inoue","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S1570-0232(04)00587-2","article-title":"Determination of perfluorooctane sulfonate, perfluorooctanoate and perfluorooctane sulfonylamide in human plasma by column-switching liquid chromatography\u2013electrospray mass spectrometry coupled with solid-phase extraction","volume":"810","author":"Inoue","year":"2004","journal-title":"J. Chromatogr. B. Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.envres.2011.10.003_bib18","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1016\/S0140-6736(97)07302-9","article-title":"Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee","volume":"351","author":"ISAAC Steering Committee","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.envres.2011.10.003_bib19","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-2605.2008.00870.x","article-title":"Emerging endocrine disrupters: perfluoroalkylated substances","volume":"31","author":"Jensen","year":"2008","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.envres.2011.10.003_bib20","doi-asserted-by":"crossref","first-page":"4489","DOI":"10.1021\/es0493446","article-title":"Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries","volume":"38","author":"Kannan","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2011.10.003_bib21","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1289\/ehp.9491","article-title":"Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996\u20132004, in Sweden","volume":"115","author":"K\u00e4rrman","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib22","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/toxsci\/kfn015","article-title":"Gestational exposure to perfluorooctane sulfonate suppresses immune function in B6C3F1 mice","volume":"103","author":"Keil","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2011.10.003_bib23","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ije\/dyq071","article-title":"Cohort profile: the Hokkaido study on environment and children's health in Japan","volume":"40","author":"Kishi","year":"2011","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.envres.2011.10.003_bib24","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/toxsci\/kfm128","article-title":"Perfluoroalkyl acids: a review of monitoring and toxicological findings","volume":"99","author":"Lau","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2011.10.003_bib25","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1289\/ehp.5860","article-title":"Consensus workshop on methods to evaluate developmental immunotoxicity","volume":"111","author":"Luster","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib26","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00420-006-0165-9","article-title":"Transplacental exposure of neonates to perfluorooctanesulfonate and perfluorooctanoate: a pilot study","volume":"80","author":"Midasch","year":"2007","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"10.1016\/j.envres.2011.10.003_bib27","unstructured":"Ministry of Education, Culture, Sports, Science and Technology, Japan. School Health Examination Survey 2010: \u3008http:\/\/www.mext.go.jp\/b_menu\/toukei\/chousa05\/hoken\/kekka\/k_detail\/__icsFiles\/afieldfile\/2011\/03\/25\/1303380_2.pdf\u3009 (accessed 27 September 2011)."},{"key":"10.1016\/j.envres.2011.10.003_bib28","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.envres.2008.06.001","article-title":"Serum levels of perfluoroalkyl compounds in human maternal and umbilical cord blood samples","volume":"108","author":"Monroy","year":"2008","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2011.10.003_bib29","first-page":"219","article-title":"Development of an analytical method for perfluorochemicals in human plasma and blood by liquid chromatography-tandem mass spectrometry coupled with solid-phase extraction using a column-switching technique","volume":"67","author":"Nakata","year":"2005","journal-title":"Organohalogen Compd."},{"key":"10.1016\/j.envres.2011.10.003_bib30","doi-asserted-by":"crossref","first-page":"877","DOI":"10.2116\/bunsekikagaku.54.877","article-title":"Development of online solid-phase extraction-HPLC\/MS\/MS method for the determination of perfluorochemicals in human plasma","volume":"9","author":"Nakata","year":"2005","journal-title":"Bunseki Kagaku"},{"key":"10.1016\/j.envres.2011.10.003_bib31","doi-asserted-by":"crossref","first-page":"653","DOI":"10.2116\/bunsekikagaku.58.653","article-title":"Determination of perfluorinated compounds in human milk and evaluation of their transition from maternal plasma","volume":"58","author":"Nakata","year":"2009","journal-title":"Bunseki Kagaku"},{"key":"10.1016\/j.envres.2011.10.003_bib32","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2332\/allergolint.O-08-550","article-title":"Surveys on the prevalence of pediatric bronchial asthma in Japan: a comparison between the 1982, 1992, and 2002 surveys conducted in the same region using the same methodology","volume":"58","author":"Nishima","year":"2009","journal-title":"Allergol. Int."},{"key":"10.1016\/j.envres.2011.10.003_bib33","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1289\/ehp.10009","article-title":"Half-life of serum elimination of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers","volume":"115","author":"Olsen","year":"2007","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib34","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1080\/15287390701252733","article-title":"Suppression of humoral immunity following exposure to the perfluorinated insecticide sulfluramid","volume":"70","author":"Peden-Adams","year":"2007","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.envres.2011.10.003_bib35","doi-asserted-by":"crossref","first-page":"6599","DOI":"10.1021\/es048340y","article-title":"Perfluorinated sulfonamides in indoor and outdoor air and indoor dust: occurrence, partitioning, and human exposure","volume":"39","author":"Shoeib","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2011.10.003_bib36","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1021\/jf0634045","article-title":"Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their packaging","volume":"55","author":"Tittlemier","year":"2007","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.envres.2011.10.003_bib37","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.chemosphere.2007.05.083","article-title":"Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan","volume":"69","author":"Todaka","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2011.10.003_bib38","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.chemosphere.2008.06.071","article-title":"Congener-specific analysis of non-dioxin-like polychlorinated biphenyls in blood collected from 195 pregnant women in Sapporo City, Japan","volume":"73","author":"Todaka","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2011.10.003_bib39","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1289\/ehp.11681","article-title":"Correlations between prenatal exposure to perfluorinated chemicals and reduced fetal growth","volume":"117","author":"Washino","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2011.10.003_bib40","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1136\/thx.2004.029561","article-title":"No increase in the prevalence of asthma, allergies, and atopic sensitisation among children in Germany: 1992\u20132001","volume":"60","author":"Z\u00f6llner","year":"2005","journal-title":"Thorax"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935111002477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935111002477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T19:52:44Z","timestamp":1757965964000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935111002477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":40,"alternative-id":["S0013935111002477"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2011.10.003","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal exposure to perfluorinated chemicals and relationship with allergies and infectious diseases in infants","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2011.10.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}