{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T18:46:31Z","timestamp":1775155591434,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.envres.2015.07.023","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T05:30:45Z","timestamp":1438925445000},"page":"461-470","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Levels of selected urinary metabolites of volatile organic compounds among children aged 6-11 years"],"prefix":"10.1016","volume":"142","author":[{"given":"Ram B.","family":"Jain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2015.07.023_bib1","unstructured":"ACS (American Cancer Society). (2013). Available at \u3008http:\/\/www.cancer.org\/cancer\/cancercauses\/tobaccocancer\/secondhand-smoke\u3009 (last accessed on\u00a013.02.14)."},{"issue":"14","key":"10.1016\/j.envres.2015.07.023_bib2","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1289\/ehp.7107","article-title":"Outdoor, indoor, and personal exposure to VOCs in children","volume":"112","author":"Adgate","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.aca.2012.04.009","article-title":"Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC\u2013ESI\/MSMS)","volume":"750","author":"Alwis","year":"2012","journal-title":"Anal. Chim. Acta"},{"issue":"3","key":"10.1016\/j.envres.2015.07.023_bib4","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1289\/ehp.1205740","article-title":"Evaluation of biomonitoring data from the CDC National Exposure Report in a risk assessment context: perspectives across chemicals","volume":"121","author":"Aylward","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib5","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/clinchem\/40.7.1401","article-title":"Blood concentrations of Volatile Organic Compounds in a nonoccupationally exposed US population and in groups with suspected exposure","volume":"40","author":"Ashley","year":"1994","journal-title":"Clin. Chem"},{"key":"10.1016\/j.envres.2015.07.023_bib6","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1002\/rcm.1580","article-title":"Simultaneous determination of t,t-muconic, S-phenylmercapturic and S-benzylmercapturic acids in urine by a rapid and sensitive liquid chromatography\/electrospray tandem mass spectrometry method","volume":"18","author":"Barbieri","year":"2004","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.envres.2015.07.023_bib7","first-page":"3","article-title":"Personal exposure to mixtures of volatile organic compounds: modeling and further analysis of the RIOPA data","volume":"181","author":"Batterman","year":"2014","journal-title":"Res. Rep. Health Eff. Inst"},{"key":"10.1016\/j.envres.2015.07.023_bib8","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1080\/10473220121418","article-title":"Multivariate analysis on levels of selected metals, particulate matter, VOC, and household characteristics and activities from the Midwestern States NHEXAS","volume":"16","author":"Bonanno","year":"2001","journal-title":"Appl. Occup. Environ. Hyg."},{"issue":"2","key":"10.1016\/j.envres.2015.07.023_bib9","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1136\/tc.2007.024158","article-title":"Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobRegproposal","volume":"17","author":"Burns","year":"2008","journal-title":"Tob. Control"},{"key":"10.1016\/j.envres.2015.07.023_bib10","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1021\/tx800479s","article-title":"Effects of eight urinary tobacco carcinogen and toxicant biomarkers","volume":"22","author":"Carmela","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.envres.2015.07.023_bib11","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/1476-069X-13-72","article-title":"Personal drinking-water exposure to tetrachloroethylene and ischemic placental disease: a retrospective cohort study","volume":"13","author":"Carwile","year":"2014","journal-title":"Environ. Health"},{"key":"10.1016\/j.envres.2015.07.023_bib12","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/j.envint.2011.05.016","article-title":"Impact of cigarette smoking on Volatile Organic Compounds (VOC) blood levels in the U.S. population: NHANES 2003\u20132004","volume":"37","author":"Chambers","year":"2011","journal-title":"Environ. Int"},{"key":"10.1016\/j.envres.2015.07.023_bib13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1080\/00039890109604068","article-title":"Recent chemical exposures and blood volatile organic compounds in a large population-based sample","volume":"56","author":"Churchill","year":"2001","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.envres.2015.07.023_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10565-015-9293-x","article-title":"Three common pathways of nephrotoxicity induced by halogenated alkenes","volume":"31","author":"Cristofori","year":"2015","journal-title":"Cell. Biol. Toxicol."},{"key":"10.1016\/j.envres.2015.07.023_bib15","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/sj.jea.7500287","article-title":"Respiratory symptoms and peak expiratory flow in children with asthma in relation to volatile organic compounds in exhaled breath and ambient air","volume":"13","author":"Delfino","year":"2003","journal-title":"J. Expo. Anal. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2015.07.023_bib16","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1021\/tx800468w","article-title":"Simultaneous determination of six mercapturic acid metabolites of volatile organic compounds in human urine","volume":"22","author":"Ding","year":"2009","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.envres.2015.07.023_bib17","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1136\/tc.12.4.424","article-title":"Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke","volume":"12","author":"Fowles","year":"2003","journal-title":"Tobacco Control"},{"key":"10.1016\/j.envres.2015.07.023_bib18","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.envint.2014.08.013","article-title":"LiNA Study Group. Prenatal VOC exposure and redecoration are related to wheezing in early infancy","volume":"73","author":"Franck","year":"2014","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2015.07.023_bib19","first-page":"e429","article-title":"Environmental tobacco smoke: health policy and focus on Italian legislation","volume":"164","author":"Giraldi","year":"2013","journal-title":"Clin Termin."},{"key":"10.1016\/j.envres.2015.07.023_bib20","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1289\/ehp.1307359","article-title":"Human health effects of tetrachloroethylene: key findings and scientific issues","volume":"122","author":"Guyton","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib23","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.scitotenv.2011.12.055","article-title":"Blood\/air distribution of volatile organic compounds (VOC) in a nationally representative sample","volume":"419","author":"Jia","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2015.07.023_bib24","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1158\/1055-9965.EPI-06-0262","article-title":"Modeling guman metabolism of benzene following occupational and environmental exposure","volume":"15","author":"Kim","year":"2006","journal-title":"Cancer Epidemiol. Biomakers Prev."},{"key":"10.1016\/j.envres.2015.07.023_bib25","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1289\/ehp.00108333","article-title":"The contribution of benzene to smoking-induced leukemia","volume":"108","author":"Korte","year":"2000","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib26","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.1007\/s11356-014-3672-3","article-title":"Measurements of chlorinated volatile organic compounds emitted from office printers and photocopiers","volume":"22","author":"Kowalska","year":"2015","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envres.2015.07.023_bib27","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.mrrev.2014.04.003","article-title":"Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity","volume":"762","author":"Lash","year":"2014","journal-title":"Mutat. Res. Rev. Mutat. Res."},{"key":"10.1016\/j.envres.2015.07.023_bib28","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/tox.10055","article-title":"The influence of maternal exposure to volatile organic compounds on the cytokine secretion profile of neonatal T cells","volume":"17","author":"Lehmann","year":"2002","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.envres.2015.07.023_bib29","doi-asserted-by":"crossref","first-page":"9676","DOI":"10.1007\/s11356-014-2904-x","article-title":"Improvement of health risk factors after reduction of VOC concentrations in industrial and urban areas","volume":"21","author":"Lerner","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.envres.2015.07.023_bib30","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/sj.jes.7500635","article-title":"Relationships between levels of volatile organic compounds in air and blood from the general population","volume":"18","author":"Lin","year":"2008","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2015.07.023_bib31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1006\/enrs.1998.3845","article-title":"Medical costs and lost productivity from health conditions at volatile organic compound-contaminated superfund sites","volume":"79","author":"Lybarger","year":"1998","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2015.07.023_bib32","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1289\/ehp.1103500","article-title":"Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda","volume":"119","author":"Matt","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib33","first-page":"733","article-title":"Volatile organic compounds, respirable dust, and personal factors related to prevalence and incidence of sick building syndrome in primary schools","volume":"47","author":"Norb\u00e4ck","year":"1990","journal-title":"Br. J. Ind. Med."},{"issue":"7","key":"10.1016\/j.envres.2015.07.023_bib34","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.envint.2010.06.003","article-title":"Benzene exposure in childhood: role of living environments and assessment of available tools","volume":"36","author":"Protano","year":"2010","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2015.07.023_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.scitotenv.2012.07.004","article-title":"Urinary trans, trans-muconic acid, S-phenylmercapturic acid are indicative of exposure to urban benzene pollution during childhood","volume":"435-436","author":"Protano","year":"2012","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2015.07.023_bib36","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1007\/s00216-010-3893-3","article-title":"Accurate quantification of mercapturic acids of styene (PHEMAs) in human urine with direct sample injection using automated column-switching high-performance liquid chromatography coupled with tandem mass spectrometry","volume":"397","author":"Reska","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.envres.2015.07.023_bib37","series-title":"The Chemical Components of Tobacco and Tobacco Smoke","author":"Rodgman","year":"2009"},{"key":"10.1016\/j.envres.2015.07.023_bib38","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/1476-069X-12-104","article-title":"Evaluation of exposure to contaminated drinking water and specific birth defects and childhood cancers at Marine Corps Base Camp Lejeune, North Carolina: a case-control study","volume":"12","author":"Ruckart","year":"2013","journal-title":"Environ. Health"},{"key":"10.1016\/j.envres.2015.07.023_bib39","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/1476-069X-13-99","article-title":"Evaluation of contaminated drinking water and preterm birth,small for gestational age, and birth weight at Marine Corps Base Camp Lejeune, North Carolina:a cross-sectional study","volume":"13","author":"Ruckart","year":"2014","journal-title":"Environ. Health"},{"key":"10.1016\/j.envres.2015.07.023_bib40","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1136\/thx.2003.013680","article-title":"Association of domestic exposure to volatile organic compounds with asthma in young children","volume":"59","author":"Rumchev","year":"2004","journal-title":"Thorax"},{"key":"10.1016\/j.envres.2015.07.023_bib41","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.jchromb.2008.01.024","article-title":"Fast determination of S-phenylmercapturic aicd (S-PMA) and S-benzylmercapturic aicd (S-BMA) by column-switching liquid chromatography\u2013tandem mass spectrometry","volume":"863","author":"Schettgen","year":"2008","journal-title":"J. Chramatogr. B Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.envres.2015.07.023_bib42","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s00216-008-2510-1","article-title":"A method for the quantification of biomarkers of exposure to acrylonitrile and 1,3-butadiene in human urine by column-switching liquid chromatography\u2013tandem mass spectrometry","volume":"393","author":"Schettgen","year":"2009","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.envres.2015.07.023_bib43","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1289\/ehp.7412","article-title":"Children\u2019s exposure to volatile organic compounds as determined by longitudinal measurements","volume":"113","author":"Sexton","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib44","doi-asserted-by":"crossref","first-page":"161","DOI":"10.5539\/gjhs.v7n1p161","article-title":"Occupational health risks among trichloroethylene-exposed workers in a clock manufacturing factory","volume":"7","author":"Singthong","year":"2014","journal-title":"Glob. J. Health Sci."},{"issue":"12","key":"10.1016\/j.envres.2015.07.023_bib45","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1158\/1055-9965.EPI-14-0548","article-title":"Intake of toxic and carcinogenic volatile organic compounds from secondhand smoke in motor vehicles","volume":"23","author":"St Helen","year":"2014","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.envres.2015.07.023_bib46","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.envres.2013.08.005","article-title":"Determinants of personal, indoor and outdoor VOC concentrations: an analysis of RIOPA data","author":"Su","year":"2013","journal-title":"Environ. Res."},{"issue":"2","key":"10.1016\/j.envres.2015.07.023_bib47","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1289\/ehp.1002318","article-title":"Occupational benzene exposure and the risk of lymphoma subtypes: a meta-analysis of cohort studies incorporating three study quality dimensions","volume":"119","author":"Vlaanderen","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib48","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1289\/ehp.1307055","article-title":"Tetrachloroethylene exposure and bladder cancer risk: a meta-analysis of dry-cleaning-worker studies","volume":"122","author":"Vlaanderen","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2015.07.023_bib49","doi-asserted-by":"crossref","first-page":"140","DOI":"10.3390\/metabo5010140","article-title":"Advances in electronic-nose technologies for the detection of volatile biomarker metabolities in the human breath","volume":"5","author":"Wilson","year":"2015","journal-title":"Metabolites"},{"key":"10.1016\/j.envres.2015.07.023_bib50","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1039\/C3EM00487B","article-title":"Underestimated public health risks caused by overestimated removal in wastewater treatment processes","volume":"16","author":"Yang","year":"2014","journal-title":"Environ. Sci. Process. Impacts"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935115300438?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935115300438?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T23:35:40Z","timestamp":1599435340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935115300438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":48,"alternative-id":["S0013935115300438"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2015.07.023","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levels of selected urinary metabolites of volatile organic compounds among children aged 6-11 years","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2015.07.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}