{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T03:01:17Z","timestamp":1791342077094,"version":"4.3.1"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T00:00:00Z","timestamp":1589414400000},"content-version":"am","delay-in-days":287,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.envres.2019.04.036","type":"journal-article","created":{"date-parts":[[2019,5,7]],"date-time":"2019-05-07T13:17:26Z","timestamp":1557235046000},"page":"22-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Heterogeneity in childhood body mass trajectories in relation to prenatal phthalate exposure"],"prefix":"10.1016","volume":"175","author":[{"given":"Brianna C.","family":"Heggeseth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Holland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenda","family":"Eskenazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Kogut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim G.","family":"Harley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2019.04.036_bib1","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1289\/ehp.1409049","article-title":"Exposure to endocrine-disrupting chemicals during pregnancy and weight at 7 Years of age: a multi-pollutant approach","volume":"123","author":"Agay-Shay","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib2","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1289\/ehp.0901331","article-title":"Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth","volume":"118","author":"Boas","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib3","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1079\/PHN2002348","article-title":"A Diet Quality Index for Pregnancy detects variation in diet and differences by sociodemographic factors","volume":"5","author":"Bodnar","year":"2002","journal-title":"Publ. Health Nutr."},{"key":"10.1016\/j.envres.2019.04.036_bib4","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.envres.2016.08.033","article-title":"Phthalate pregnancy exposure and male offspring growth from the intra-uterine period to five years of age","volume":"151","author":"Botton","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2019.04.036_bib5","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","author":"Breiman","year":"2001","journal-title":"Mach. Learn."},{"key":"10.1016\/j.envres.2019.04.036_bib6","series-title":"Classification and Regression Trees","author":"Breiman","year":"1984"},{"key":"10.1016\/j.envres.2019.04.036_bib7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/EDE.0000000000000436","article-title":"Prenatal phthalate exposures and body mass index among 4- to 7-Year-old Children: a pooled analysis","volume":"27","author":"Buckley","year":"2016","journal-title":"Epidemiology"},{"key":"10.1016\/j.envres.2019.04.036_bib8","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1289\/ehp.1509788","article-title":"Prenatal phthalate exposures and childhood fat mass in a New York City cohort","volume":"124","author":"Buckley","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib9","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.ijheh.2014.02.005","article-title":"Age and sex differences in childhood and adulthood obesity association with phthalates: analyses of NHANES 2007-2010","volume":"217","author":"Buser","year":"2014","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.envres.2019.04.036_bib10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.envint.2018.01.023","article-title":"Excretion of Di-2-ethylhexyl phthalate (DEHP) metabolites in urine is related to body mass index because of higher energy intake in the overweight and obese","volume":"113","author":"Campbell","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2019.04.036_bib11","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1080\/01621459.1979.10481038","article-title":"Robust locally weighted regression and smoothing scatterplots","volume":"74","author":"Cleveland","year":"1979","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.envres.2019.04.036_bib12","series-title":"Approximation Theory II","first-page":"1","article-title":"Splines as linear combinations of B-splines. A survey","author":"De Boor","year":"1976"},{"key":"10.1016\/j.envres.2019.04.036_bib13","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/0021-9045(72)90080-9","article-title":"On calculating with B-splines","volume":"6","author":"De Boor","year":"1972","journal-title":"J. Approx. Theory"},{"key":"10.1016\/j.envres.2019.04.036_bib14","doi-asserted-by":"crossref","first-page":"7001","DOI":"10.3390\/ijerph110707001","article-title":"First year growth in relation to prenatal exposure to endocrine disruptors \u2014 a Dutch prospective cohort study","volume":"11","author":"De Cock","year":"2014","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.envres.2019.04.036_bib15","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.mce.2009.02.017","article-title":"PPAR-mediated activity of phthalates: a link to the obesity epidemic?","volume":"304","author":"Desvergne","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2019.04.036_bib16","series-title":"Refund: Regression with Functional Data","author":"Goldsmith","year":"2016"},{"key":"10.1016\/j.envres.2019.04.036_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12982-015-0038-3","article-title":"Modelling subject-specific childhood growth using linear mixed-effect models with cubic regression splines","volume":"13","author":"Grajeda","year":"2016","journal-title":"Emerg. Themes Epidemiol."},{"key":"10.1016\/j.envres.2019.04.036_bib18","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/pr.2017.112","article-title":"Association of prenatal urinary phthalate metabolite concentrations and childhood BMI and obesity","volume":"82","author":"Harley","year":"2017","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.envres.2019.04.036_bib19","series-title":"Generalized Additive Models","author":"Hastie","year":"1990"},{"key":"10.1016\/j.envres.2019.04.036_bib20","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0209321","article-title":"Early-life environmental exposures and childhood growth: a comparison of statistical methods","volume":"13","author":"Heggeseth","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2019.04.036_bib21","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1214\/17-AOAS1066","article-title":"How Gaussian mixture models might miss detecting factors that impact growth patterns","volume":"12","author":"Heggeseth","year":"2018","journal-title":"Ann. Appl. Stat."},{"key":"10.1016\/j.envres.2019.04.036_bib22","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/toxsci\/kfg145","article-title":"Activation of PPARalpha and PPARgamma by environmental phthalate monoesters","volume":"74","author":"Hurst","year":"2003","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"10.1016\/j.envres.2019.04.036_bib23","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.envint.2016.09.013","article-title":"A global assessment of phthalates burden and related links to health effects","volume":"97","author":"Katsikantami","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2019.04.036_bib24","first-page":"13","article-title":"Non-monotonic dose-response relationships and endocrine disruptors: a qualitative method of assessment","volume":"14","author":"Lagarde","year":"2015","journal-title":"Environ. Health Glob. Access Sci. Source"},{"key":"10.1016\/j.envres.2019.04.036_bib25","doi-asserted-by":"crossref","first-page":"963","DOI":"10.2307\/2529876","article-title":"Random-effects models for longitudinal data","volume":"38","author":"Laird","year":"1982","journal-title":"Biometrics"},{"key":"10.1016\/j.envres.2019.04.036_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/biomet\/73.1.13","article-title":"Longitudinal data analysis using generalized linear models","volume":"73","author":"Liang","year":"1986","journal-title":"Biometrika"},{"key":"10.1016\/j.envres.2019.04.036_bib27","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.jpeds.2012.07.053","article-title":"Growth during infancy and childhood, and adiposity at age 16 years: ages 2 to 7 years are pivotal","volume":"162","author":"Liem","year":"2013","journal-title":"J. Pediatr."},{"key":"10.1016\/j.envres.2019.04.036_bib28","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1289\/ehp.7199","article-title":"Epidemiologic evaluation of measurement data in the presence of detection limits","volume":"112","author":"Lubin","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib29","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1002\/oby.21359","article-title":"DEHP induces obesity and hypothyroidism through both central and peripheral pathways in C3H\/He mice","volume":"24","author":"Lv","year":"2016","journal-title":"Obes. Silver Spring Md"},{"key":"10.1016\/j.envres.2019.04.036_bib30","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1289\/ehp.1408750","article-title":"Prenatal exposure to phthalates and childhood body size in an urban cohort","volume":"124","author":"Maresca","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.0006-341X.1999.00463.x","article-title":"Finite mixture modeling with mixture outcomes using the EM algorithm","volume":"55","author":"Muth\u00e9n","year":"1999","journal-title":"Biometrics"},{"key":"10.1016\/j.envres.2019.04.036_bib32","series-title":"Lcmm: Estimation of Extended Mixed Models Using Latent Classes and Latent Processes","author":"Proust-Lima","year":"2014"},{"key":"10.1016\/j.envres.2019.04.036_bib33","series-title":"R: A Language and Environment for Statistical Computing","year":"2018"},{"key":"10.1016\/j.envres.2019.04.036_bib34","series-title":"Functional Data Analysis","author":"Ramsay","year":"2005"},{"key":"10.1016\/j.envres.2019.04.036_bib35","series-title":"Applied Functional Data Analysis: Methods and Case Studies","author":"Ramsay","year":"2002"},{"key":"10.1016\/j.envres.2019.04.036_bib36","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10903-010-9332-x","article-title":"Factors associated with overweight and obesity among children of Mexican descent: results of a binational study","volume":"13","author":"Rosas","year":"2011","journal-title":"J. Immigr. Minority Health"},{"key":"10.1016\/j.envres.2019.04.036_bib37","doi-asserted-by":"crossref","first-page":"097008","DOI":"10.1289\/EHP1022","article-title":"Early-life phthalate exposure and adiposity at 8 Years of age","volume":"125","author":"Shoaff","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib38","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.jchromb.2007.10.023","article-title":"Quantification of 22 phthalate metabolites in human urine","volume":"860","author":"Silva","year":"2007","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.envres.2019.04.036_bib39","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.tox.2005.02.002","article-title":"Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor","volume":"210","author":"Takeuchi","year":"2005","journal-title":"Toxicology"},{"key":"10.1016\/j.envres.2019.04.036_bib40","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1289\/ehp.1104597","article-title":"Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review","volume":"120","author":"Thayer","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib41","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1289\/ehp.1205526","article-title":"Race\/ethnicity\u2013specific associations of urinary phthalates with childhood body mass in a nationally representative sample","volume":"121","author":"Trasande","year":"2013","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib42","series-title":"CDC Growth Charts: United States","year":"2000"},{"key":"10.1016\/j.envres.2019.04.036_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2018.00327","article-title":"Association of early life exposure to phthalates with obesity and cardiometabolic traits in childhood: sex specific associations","volume":"6","author":"Vafeiadi","year":"2018","journal-title":"Front. Public Health"},{"key":"10.1016\/j.envres.2019.04.036_bib44","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1289\/ehp.1408887","article-title":"Prenatal phthalate exposure and childhood growth and blood pressure: evidence from the Spanish INMA-Sabadell birth cohort study","volume":"123","author":"Valvi","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2019.04.036_bib45","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1210\/er.2011-1050","article-title":"Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses","volume":"33","author":"Vandenberg","year":"2012","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.envres.2019.04.036_bib46","article-title":"Urinary phthalate metabolites are associated with body mass index and waist circumference in Chinese school children","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2019.04.036_bib47","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1198\/016214504000000980","article-title":"Stable and efficient multiple smoothing parameter estimation for generalized additive models","volume":"99","author":"Wood","year":"2004","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.envres.2019.04.036_bib48","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.envres.2017.03.038","article-title":"Bisphenol A and phthalates in utero and in childhood: association with child BMI z-score and adiposity","volume":"156","author":"Yang","year":"2017","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2019.04.036_bib49","doi-asserted-by":"crossref","DOI":"10.1186\/s12887-017-0831-y","article-title":"Characterizing early child growth patterns of height-for-age in an urban slum cohort of Bangladesh with functional principal component analysis","volume":"17","author":"Zhang","year":"2017","journal-title":"BMC Pediatr."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393511930252X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393511930252X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T20:03:14Z","timestamp":1757966594000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001393511930252X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":49,"alternative-id":["S001393511930252X"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2019.04.036","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heterogeneity in childhood body mass trajectories in relation to prenatal phthalate exposure","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2019.04.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}