{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T21:15:44Z","timestamp":1758057344630,"version":"3.44.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.envres.2020.110467","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T04:12:04Z","timestamp":1605240724000},"page":"110467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Exploration of identifying novel serum biomarkers for malignant mesothelioma using iTRAQ combined with 2D-LC-MS\/MS"],"prefix":"10.1016","volume":"193","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1385-442X","authenticated-orcid":false,"given":"Hailing","family":"Xia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingfang","family":"Feng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijun","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoqiang","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junqiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6499-2473","authenticated-orcid":false,"given":"Wei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shibo","family":"Ying","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Ju","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4052-7865","authenticated-orcid":false,"given":"Jianlin","family":"Lou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2020.110467_bib1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1164\/rccm.200310-1436ST","article-title":"Diagnosis and initial management of nonmalignant diseases related to asbestos","volume":"170","author":"American Thoracic","year":"2004","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envres.2020.110467_bib2","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1158\/1078-0432.CCR-08-1402","article-title":"Nuclear versus cytoplasmic localization of filamin A in prostate cancer: immunohistochemical correlation with metastases","volume":"15","author":"Bedolla","year":"2009","journal-title":"Clin. Canc. Res."},{"key":"10.1016\/j.envres.2020.110467_bib3","doi-asserted-by":"crossref","DOI":"10.1001\/jamaoncol.2019.0446","article-title":"High time for complete ban on asbestos use in developing countries","author":"Chen","year":"2019","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.envres.2020.110467_bib4","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1038\/sj.bjc.6604760","article-title":"Fibulin 1 is downregulated through promoter hypermethylation in gastric cancer","volume":"99","author":"Cheng","year":"2008","journal-title":"Br. J. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib5","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1179\/1077352512Z.00000000021","article-title":"An updated review on asbestos and related diseases in China","volume":"18","author":"Courtice","year":"2012","journal-title":"Int. J. Occup. Environ. Health"},{"key":"10.1016\/j.envres.2020.110467_bib6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.21873\/cgp.20023","article-title":"A proteomic analysis of the malignant mesothelioma secretome using iTRAQ","volume":"14","author":"Creaney","year":"2017","journal-title":"CANCER GENOMICS PROTEOMICS"},{"key":"10.1016\/j.envres.2020.110467_bib7","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1038\/s41467-019-08480-y","article-title":"Deciphering the complex role of thrombospondin-1 in glioblastoma development","volume":"10","author":"Daubon","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envres.2020.110467_bib8","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/ajim.22206","article-title":"Potential years of life lost (PYLL) caused by asbestos-related diseases in the world","volume":"56","author":"Diandini","year":"2013","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.envres.2020.110467_bib9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/ajim.20209","article-title":"The global burden of disease due to occupational carcinogens","volume":"48","author":"Driscoll","year":"2005","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.envres.2020.110467_bib10","doi-asserted-by":"crossref","first-page":"7649","DOI":"10.1158\/0008-5472.CAN-11-0833","article-title":"Thrombospondin-1 triggers cell migration and development of advanced prostate tumors","volume":"71","author":"Firlej","year":"2011","journal-title":"Canc. Res."},{"key":"10.1016\/j.envres.2020.110467_bib11","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph15051000","article-title":"Global asbestos disaster","author":"Furuya","year":"2018","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2020.110467_bib12","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.molmed.2005.06.001","article-title":"Fibulins and cancer: friend or foe?","volume":"11","author":"Gallagher","year":"2005","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.envres.2020.110467_bib13","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/sj.bjc.6600802","article-title":"Elevated expression and altered processing of fibulin-1 protein in human breast cancer","volume":"88","author":"Greene","year":"2003","journal-title":"Br. J. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib14","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1158\/2159-8290.CD-18-0804","article-title":"Integrative molecular characterization of malignant pleural mesothelioma","volume":"8","author":"Hmeljak","year":"2018","journal-title":"Canc. Discov."},{"key":"10.1016\/j.envres.2020.110467_bib15","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1164\/rccm.200907-1020OC","article-title":"Diagnostic performance of soluble mesothelin and megakaryocyte potentiating factor in mesothelioma","volume":"181","author":"Hollevoet","year":"2010","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envres.2020.110467_bib16","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1074\/mcp.M115.057026","article-title":"Identification and characterization of potential biomarkers by quantitative tissue proteomics of primary lung adenocarcinoma","volume":"15","author":"Hsu","year":"2016","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.envres.2020.110467_bib17","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1038\/onc.2016.319","article-title":"Beta-adrenergic signaling promotes tumor angiogenesis and prostate cancer progression through HDAC2-mediated suppression of thrombospondin-1","volume":"36","author":"Hulsurkar","year":"2017","journal-title":"Oncogene"},{"key":"10.1016\/j.envres.2020.110467_bib18","doi-asserted-by":"crossref","first-page":"647","DOI":"10.5858\/arpa.2012-0214-OA","article-title":"Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group","volume":"137","author":"Husain","year":"2013","journal-title":"Arch. Pathol. Lab Med."},{"key":"10.1016\/j.envres.2020.110467_bib19","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nrc2561","article-title":"Regulation of nitric oxide signalling by thrombospondin 1: implications for anti-angiogenic therapies","volume":"9","author":"Isenberg","year":"2009","journal-title":"Nat. Rev. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib20","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1158\/1078-0432.CCR-15-0879","article-title":"Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 Months prior to clinical diagnosis: association with diabetes mellitus","volume":"22","author":"Jenkinson","year":"2016","journal-title":"Clin. Canc. Res."},{"key":"10.1016\/j.envres.2020.110467_bib21","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1725354","article-title":"Plasma fibulin-3 as a potential biomarker for patients with asbestos-related diseases in the han population","author":"Jiang","year":"2017","journal-title":"Dis. Markers"},{"key":"10.1016\/j.envres.2020.110467_bib22","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1007\/s00018-007-7486-z","article-title":"Thrombospondins in cancer","volume":"65","author":"Kazerounian","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.envres.2020.110467_bib23","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1093\/carcin\/bgs299","article-title":"CXCL1\/GROalpha increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-kappaB\/HDAC1 epigenetic regulation","volume":"33","author":"Kuo","year":"2012","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.envres.2020.110467_bib24","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ijc.28662","article-title":"Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis","volume":"135","author":"Kwon","year":"2014","journal-title":"Int. J. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib25","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1080\/10937404.2016.1195323","article-title":"Mesothelioma from asbestos exposures: epidemiologic patterns and impact in the United States","volume":"19","author":"Lemen","year":"2016","journal-title":"J. Toxicol. Environ. Health Part B"},{"key":"10.1016\/j.envres.2020.110467_bib26","doi-asserted-by":"crossref","first-page":"10070","DOI":"10.1038\/s41598-018-28297-x","article-title":"Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo","volume":"8","author":"Li","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envres.2020.110467_bib27","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1038\/bjc.2017.365","article-title":"A new panel of pancreatic cancer biomarkers discovered using a mass spectrometry-based pipeline","volume":"117","author":"Liu","year":"2017","journal-title":"Br. J. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib28","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1503\/cmaj.080129","article-title":"Canadian cancer statistics at a glance: mesothelioma","volume":"178","author":"Marrett","year":"2008","journal-title":"CMAJ (Can. Med. Assoc. J.)"},{"key":"10.1016\/j.envres.2020.110467_bib29","doi-asserted-by":"crossref","first-page":"214","DOI":"10.15585\/mmwr.mm6608a3","article-title":"Malignant mesothelioma mortality - United States, 1999-2015","volume":"66","author":"Mazurek","year":"2017","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.envres.2020.110467_bib30","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/sj.onc.1205171","article-title":"Estrogen induction and overexpression of fibulin-1C mRNA in ovarian cancer cells","volume":"21","author":"Moll","year":"2002","journal-title":"Oncogene"},{"key":"10.1016\/j.envres.2020.110467_bib31","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1074\/mcp.M113.030775","article-title":"Proteome screening of pleural effusions identifies galectin 1 as a diagnostic biomarker and highlights several prognostic biomarkers for malignant mesothelioma","volume":"13","author":"Mundt","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.envres.2020.110467_bib32","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1476-4598-11-50","article-title":"Targeting filamin A reduces K-RAS-induced lung adenocarcinomas and endothelial response to tumor growth in mice","volume":"11","author":"Nallapalli","year":"2012","journal-title":"Mol. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib33","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1158\/1078-0432.CCR-15-1130","article-title":"HMGB1 and its hyperacetylated isoform are sensitive and specific serum biomarkers to detect asbestos exposure and to identify mesothelioma patients","volume":"22","author":"Napolitano","year":"2016","journal-title":"Clin. Canc. Res."},{"key":"10.1016\/j.envres.2020.110467_bib34","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1056\/NEJMoa1115050","article-title":"Fibulin-3 as a blood and effusion biomarker for pleural mesothelioma","volume":"367","author":"Pass","year":"2012","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envres.2020.110467_bib35","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0140-6736(03)14794-0","article-title":"Mesothelin-family proteins and diagnosis of mesothelioma","volume":"362","author":"Robinson","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.envres.2020.110467_bib36","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1056\/NEJMra050152","article-title":"Advances in malignant mesothelioma","volume":"353","author":"Robinson","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envres.2020.110467_bib37","doi-asserted-by":"crossref","first-page":"R341","DOI":"10.1530\/ERC-13-0364","article-title":"The dual role of filamin A in cancer: can't live with (too much of) it, can't live without it","volume":"20","author":"Savoy","year":"2013","journal-title":"Endocr. Relat. Canc."},{"key":"10.1016\/j.envres.2020.110467_bib38","doi-asserted-by":"crossref","DOI":"10.1183\/09031936.00063109","article-title":"Guidelines of the European respiratory society and the European society of thoracic surgeons for the management of malignant pleural mesothelioma","author":"Scherpereel","year":"2010","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.envres.2020.110467_bib39","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1074\/mcp.T600050-MCP200","article-title":"The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra","volume":"6","author":"Shilov","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.envres.2020.110467_bib40","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1146\/annurev-publhealth-031811-124704","article-title":"The worldwide pandemic of asbestos-related diseases","volume":"34","author":"Stayner","year":"2013","journal-title":"Annu. Rev. Publ. Health"},{"key":"10.1016\/j.envres.2020.110467_bib41","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/35052082","article-title":"Filamins as integrators of cell mechanics and signalling","volume":"2","author":"Stossel","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envres.2020.110467_bib42","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/nrm1130","article-title":"Fibulins: a versatile family of extracellular matrix proteins","volume":"4","author":"Timpl","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envres.2020.110467_bib43","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19010238","article-title":"Heterogeneous contributing factors in MPM disease development and progression: biological advances and clinical implications","volume":"19","author":"Tolani","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envres.2020.110467_bib44","doi-asserted-by":"crossref","first-page":"4587","DOI":"10.1242\/jcs.114.24.4587","article-title":"Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility","volume":"114","author":"Twal","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.envres.2020.110467_bib45","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.neuroscience.2016.05.055","article-title":"iTRAQ technology-based identification of human peripheral serum proteins associated with depression","volume":"330","author":"Wang","year":"2016","journal-title":"Neuroscience"},{"key":"10.1016\/j.envres.2020.110467_bib46","doi-asserted-by":"crossref","first-page":"15330","DOI":"10.1002\/jcp.28180","article-title":"Suppression of OSCC malignancy by oral glands derived-PIP identified by iTRAQ combined with 2D LC-MS\/MS","volume":"234","author":"Wang","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.envres.2020.110467_bib47","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.yexcr.2017.07.035","article-title":"Filamin A upregulation correlates with Snail-induced epithelial to mesenchymal transition (EMT) and cell adhesion but its inhibition increases the migration of colon adenocarcinoma HT29 cells","volume":"359","author":"Wieczorek","year":"2017","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.envres.2020.110467_bib48","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/j.celrep.2014.08.034","article-title":"Prox 1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance","volume":"8","author":"Wiener","year":"2014","journal-title":"Cell Rep."},{"key":"10.1016\/j.envres.2020.110467_bib49","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.juro.2013.01.098","article-title":"Fibulin-1 is down-regulated through promoter hypermethylation and suppresses renal cell carcinoma progression","volume":"190","author":"Xiao","year":"2013","journal-title":"J. Urol."},{"key":"10.1016\/j.envres.2020.110467_bib50","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1084\/jem.20100433","article-title":"Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion","volume":"207","author":"Xu","year":"2010","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.envres.2020.110467_bib51","doi-asserted-by":"crossref","first-page":"M111","DOI":"10.1074\/mcp.M111.013946","article-title":"Identification of candidate biomarkers for early detection of human lung squamous cell cancer by quantitative proteomics","volume":"11","author":"Zeng","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.envres.2020.110467_bib52","doi-asserted-by":"crossref","first-page":"8199","DOI":"10.1158\/0008-5472.CAN-09-4562","article-title":"Silencing of thrombospondin-1 is critical for myc-induced metastatic phenotypes in medulloblastoma","volume":"70","author":"Zhou","year":"2010","journal-title":"Canc. Res."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935120313645?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935120313645?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T20:28:43Z","timestamp":1757968123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935120313645"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":52,"alternative-id":["S0013935120313645"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2020.110467","relation":{},"ISSN":["0013-9351"],"issn-type":[{"type":"print","value":"0013-9351"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exploration of identifying novel serum biomarkers for malignant mesothelioma using iTRAQ combined with 2D-LC-MS\/MS","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2020.110467","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110467"}}