{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:59:44Z","timestamp":1790135984974,"version":"4.0.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52200144"],"award-info":[{"award-number":["52200144"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U20A20326"],"award-info":[{"award-number":["U20A20326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2021M693722"],"award-info":[{"award-number":["2021M693722"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.envres.2023.115324","type":"journal-article","created":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T10:30:53Z","timestamp":1674037853000},"page":"115324","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Effect of granular activated carbon and chloroform on chain elongation with simple substrate ethanol and acetate"],"prefix":"10.1016","volume":"221","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4241-2420","authenticated-orcid":false,"given":"Lin","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linji","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2787-4694","authenticated-orcid":false,"given":"Junguo","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.envres.2023.115324_bib1","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1021\/acs.est.5b04847","article-title":"Chain elongation with reactor microbiomes: open-culture biotechnology to produce biochemicals","volume":"50","author":"Angenent","year":"2016","journal-title":"Environ. Sci. Technol."},{"issue":"Pt 2","key":"10.1016\/j.envres.2023.115324_bib2","article-title":"Phylogenomic analyses of clostridia and identification of novel protein signatures that are specific to the genus Clostridium sensu stricto (cluster I)","volume":"59","author":"Beile","year":"2009","journal-title":"Int. J. Syst. Evol. Microbiol."},{"issue":"4","key":"10.1016\/j.envres.2023.115324_bib3","article-title":"The phylogeny of the genus Clostridium: proposal of five new genera and eleven new species combinations","volume":"44","author":"D","year":"1994","journal-title":"Int. J. Syst. Bacteriol."},{"key":"10.1016\/j.envres.2023.115324_bib4","unstructured":"Briki, A., Kabore, K., Olmos, E., Bosselaar, S., Blanchard, F., Fick, M., Guedon, E., Fournier, F., Delaunay, S. Corynebacterium glutamicum, a natural overproducer of succinic acid? Eng. Life Sci., 11."},{"issue":"3","key":"10.1016\/j.envres.2023.115324_bib5","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/j.biortech.2008.09.014","article-title":"Optimal production of polyhydroxyalkanoates (PHA) in activated sludge fed by volatile fatty acids (VFAs) generated from alkaline excess sludge fermentation","volume":"100","author":"Cai","year":"2009","journal-title":"Bioresour. Technol."},{"issue":"3","key":"10.1016\/j.envres.2023.115324_bib6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jbiotec.2011.07.004","article-title":"Genetic manipulation of butyrate formation pathways in Clostridium butyricum","volume":"155","author":"Cai","year":"2011","journal-title":"J. Biotechnol."},{"issue":"12","key":"10.1016\/j.envres.2023.115324_bib7","doi-asserted-by":"crossref","first-page":"6467","DOI":"10.1021\/acs.est.5b06021","article-title":"Product diversity linked to substrate usage in chain elongation by mixed-culture fermentation","volume":"50","author":"Coma","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib8","volume":"vol. 169","author":"Contreras-Davila","year":"2020"},{"issue":"19","key":"10.1016\/j.envres.2023.115324_bib9","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1093\/bioinformatics\/btq461","article-title":"Search and clustering orders of magnitude faster than BLAST","volume":"26","author":"Edgar","year":"2010","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.envres.2023.115324_bib10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S1389-1723(00)88048-2","article-title":"Characterization of a bioflocculant produced by Citrobacter sp TKF04 from acetic and propionic acids","volume":"89","author":"Fujita","year":"2000","journal-title":"J. Biosci. Bioeng."},{"key":"10.1016\/j.envres.2023.115324_bib11","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.biortech.2020.124236","article-title":"Biochar and activated carbon enhance ethanol conversion and selectivity to caproic acid by Clostridium kluyveri","volume":"319","author":"Ghysels","year":"2021","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2020.122977","article-title":"Butyric acid production from spent coffee grounds by engineered Clostridium tyrobutyricum overexpressing galactose catabolism genes","volume":"304","author":"He","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib13","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.chemosphere.2021.131278","article-title":"Medium chain fatty acids production from simple substrate and waste activated sludge with ethanol as the electron donor","volume":"283","author":"He","year":"2021","journal-title":"Chemosphere"},{"issue":"2\u20133","key":"10.1016\/j.envres.2023.115324_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1574-6941.2001.tb00893.x","article-title":"Competition between homoacetogenic bacteria and methanogenic archaea for hydrogen at low temperature","volume":"38","author":"Kotsyurbenko","year":"2001","journal-title":"FEMS (Fed. Eur. Microbiol. Soc.) Microbiol. Ecol."},{"key":"10.1016\/j.envres.2023.115324_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2016.02.018","article-title":"Conversion of l-lactate into n-caproate by a continuously fed reactor microbiome","volume":"93","author":"Kucek","year":"2016","journal-title":"Water Res."},{"issue":"11","key":"10.1016\/j.envres.2023.115324_bib16","doi-asserted-by":"crossref","first-page":"3482","DOI":"10.1039\/C6EE01487A","article-title":"High n-caprylate productivities and specificities from dilute ethanol and acetate: chain elongation with microbiomes to upgrade products from syngas fermentation","volume":"9","author":"Kucek","year":"2016","journal-title":"Energy Environ. Sci."},{"key":"10.1016\/j.envres.2023.115324_bib17","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.cej.2017.02.098","article-title":"Methanogenic population dynamics regulated by bacterial community responses to protein-rich organic wastes in a high solid anaerobic digester","volume":"317","author":"Li","year":"2017","journal-title":"Chem. Eng. J."},{"issue":"12","key":"10.1016\/j.envres.2023.115324_bib18","doi-asserted-by":"crossref","first-page":"16819","DOI":"10.1021\/acssuschemeng.8b04115","article-title":"Efficient volatile fatty acids production from waste activated sludge after ferrate pretreatment with alkaline environment and the responding microbial community shift","volume":"6","author":"Li","year":"2018","journal-title":"ACS Sustain. Chem. Eng."},{"key":"10.1016\/j.envres.2023.115324_bib19","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.cej.2017.09.103","article-title":"Enhanced bioproduction of short-chain fatty acids from waste activated sludge by potassium ferrate pretreatment","volume":"332","author":"Li","year":"2018","journal-title":"Chem. Eng. J."},{"issue":"31","key":"10.1016\/j.envres.2023.115324_bib20","doi-asserted-by":"crossref","DOI":"10.1128\/MRA.00244-19","article-title":"Draft genome sequence of Rummeliibacillus sp. strain TYF005, a physiologically recalcitrant bacterium with high ethanol and salt tolerance isolated from spoilage vinegar","volume":"8","author":"Li","year":"2019","journal-title":"Microbiology Resource Announcements"},{"key":"10.1016\/j.envres.2023.115324_bib21","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.watres.2017.04.050","article-title":"Significant enhancement by biochar of caproate production via chain elongation","volume":"119","author":"Liu","year":"2017","journal-title":"Water Res."},{"key":"10.1016\/j.envres.2023.115324_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cej.2020.124577","article-title":"CO as electron donor for efficient medium chain carboxylate production by chain elongation: microbial and thermodynamic insights","volume":"390","author":"Liu","year":"2020","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.envres.2023.115324_bib23","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jclepro.2022.132757","article-title":"Granular activated carbon stimulated caproate production through chain elongation in fluidized cathode electro-fermentation systems","volume":"365","author":"Ma","year":"2022","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.envres.2023.115324_bib24","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fbioe.2019.00433","article-title":"Acetogenic fermentation from oxygen containing waste gas","volume":"7","author":"Mohr","year":"2019","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.envres.2023.115324_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125072","article-title":"The role of a newly isolated strain Corynebacterium pollutisoli SPH6 in waste activated sludge alkaline fermentation","volume":"241","author":"Pang","year":"2020","journal-title":"Chemosphere"},{"issue":"12","key":"10.1016\/j.envres.2023.115324_bib26","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.bbapap.2008.08.012","article-title":"Acetogenesis and the Wood-Ljungdahl pathway of CO2 fixation","volume":"1784","author":"Ragsdale","year":"2008","journal-title":"Biochim. Biophys. Acta, Proteins Proteomics"},{"issue":"10","key":"10.1016\/j.envres.2023.115324_bib27","doi-asserted-by":"crossref","first-page":"5814","DOI":"10.1128\/AEM.71.10.5814-5822.2005","article-title":"Use of 16S rRNA gene terminal restriction fragment analysis to assess the impact of solids retention time on the bacterial diversity of activated sludge","volume":"71","author":"Saikaly","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"issue":"4","key":"10.1016\/j.envres.2023.115324_bib28","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1007\/BF00412211","article-title":"Considerations on the energy metabolism of Clostridium kluyveri","volume":"65","author":"Schoberth","year":"1969","journal-title":"Archiv fur Mikrobiologie"},{"issue":"6","key":"10.1016\/j.envres.2023.115324_bib29","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1073\/pnas.0711093105","article-title":"The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features","volume":"105","author":"Seedorf","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.envres.2023.115324_bib30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.copbio.2014.01.003","article-title":"Chain elongation in anaerobic reactor microbiomes to recover resources from waste","volume":"27","author":"Spirito","year":"2014","journal-title":"Curr. Opin. Biotechnol."},{"issue":"22","key":"10.1016\/j.envres.2023.115324_bib31","doi-asserted-by":"crossref","first-page":"13438","DOI":"10.1021\/acs.est.8b03856","article-title":"Higher substrate ratios of ethanol to acetate steered chain elongation toward n-caprylate in a bioreactor with product extraction","volume":"52","author":"Spirito","year":"2018","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envres.2023.115324_bib32","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1039\/C0EE00282H","article-title":"Biological formation of caproate and caprylate from acetate: fuel and chemical production from low grade biomass","volume":"4","author":"Steinbusch","year":"2011","journal-title":"Energy Environ. Sci."},{"key":"10.1016\/j.envres.2023.115324_bib33","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.biortech.2015.06.020","article-title":"Characterization of the anaerobic denitrification bacterium Acinetobacter sp SZ28 and its application for groundwater treatment","volume":"192","author":"Su","year":"2015","journal-title":"Bioresour. Technol."},{"issue":"16","key":"10.1016\/j.envres.2023.115324_bib34","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Wang","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.envres.2023.115324_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cej.2020.124436","article-title":"Breaking the loop: tackling homoacetogenesis by chloroform to halt hydrogen production-consumption loop in single chamber microbial electrolysis cells","volume":"389","author":"Wang","year":"2020","journal-title":"Chem. Eng. J."},{"issue":"17","key":"10.1016\/j.envres.2023.115324_bib36","doi-asserted-by":"crossref","first-page":"10904","DOI":"10.1021\/acs.est.0c03029","article-title":"Zerovalent iron effectively enhances medium-chain fatty acids production from waste activated sludge through improving sludge biodegradability and electron transfer efficiency","volume":"54","author":"Wang","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib37","series-title":"Ammonia Amendment Promotes High Rate Lactate Production and Recovery from Semi-continuous Food Waste Fermentation","first-page":"302","author":"Wenjuan","year":"2020"},{"issue":"19","key":"10.1016\/j.envres.2023.115324_bib38","doi-asserted-by":"crossref","first-page":"11551","DOI":"10.1021\/acs.est.5b03381","article-title":"Involvement in denitrification is beneficial to the biofilm lifestyle of Comamonas testosteroni: a mechanistic study and its environmental implications","volume":"49","author":"Wu","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib39","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.watres.2018.08.046","article-title":"Upgrading liquor-making wastewater into medium chain fatty acid: insights into co-electron donors, key microflora, and energy harvest","volume":"145","author":"Wu","year":"2018","journal-title":"Water Res."},{"key":"10.1016\/j.envres.2023.115324_bib40","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.watres.2019.115218","article-title":"Unveiling the mechanisms of medium-chain fatty acid production from waste activated sludge alkaline fermentation liquor through physiological, thermodynamic and metagenomic investigations","volume":"169","author":"Wu","year":"2020","journal-title":"Water Res."},{"issue":"8","key":"10.1016\/j.envres.2023.115324_bib41","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1016\/j.biortech.2009.10.059","article-title":"Effect of classic methanogenic inhibitors on the quantity and diversity of archaeal community and the reductive homoacetogenic activity during the process of anaerobic sludge digestion","volume":"101","author":"Xu","year":"2010","journal-title":"Bioresour. Technol."},{"issue":"6","key":"10.1016\/j.envres.2023.115324_bib42","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1007\/s00253-010-2708-y","article-title":"Typical methanogenic inhibitors can considerably alter bacterial populations and affect the interaction between fatty acid degraders and homoacetogens","volume":"87","author":"Xu","year":"2010","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"31","key":"10.1016\/j.envres.2023.115324_bib43","doi-asserted-by":"crossref","first-page":"6847","DOI":"10.1039\/C5CC01897H","article-title":"In-line and selective phase separation of medium-chain carboxylic acids using membrane electrolysis","volume":"51","author":"Xu","year":"2015","journal-title":"Chem. Commun."},{"issue":"2","key":"10.1016\/j.envres.2023.115324_bib44","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.joule.2017.11.008","article-title":"Temperature-phased conversion of acid whey waste into medium-chain carboxylic acids via lactic acid: No external e-donor","volume":"2","author":"Xu","year":"2018","journal-title":"Joule"},{"issue":"9","key":"10.1016\/j.envres.2023.115324_bib45","doi-asserted-by":"crossref","first-page":"5864","DOI":"10.1021\/acs.est.9b07651","article-title":"Enrichment versus bioaugmentation-microbiological production of caproate from mixed carbon sources by mixed bacterial culture and Clostridium kluyveri","volume":"54","author":"Zagrodnik","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib46","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.biortech.2020.122881","article-title":"Ammonia amendment promotes high rate lactate production and recovery from semi-continuous food waste fermentation","volume":"302","author":"Zhang","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.envres.2023.115324_bib47","volume":"vol. 297","author":"Zhongyang","year":"2020"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935123001160?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935123001160?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T16:59:02Z","timestamp":1781888342000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935123001160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":47,"alternative-id":["S0013935123001160"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2023.115324","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of granular activated carbon and chloroform on chain elongation with simple substrate ethanol and acetate","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2023.115324","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115324"}}