{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T11:55:25Z","timestamp":1781265325488,"version":"3.54.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T00:00:00Z","timestamp":1719705600000},"content-version":"am","delay-in-days":303,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["ES02284401"],"award-info":[{"award-number":["ES02284401"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["P42ES05947"],"award-info":[{"award-number":["P42ES05947"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["P01 R01ES032202"],"award-info":[{"award-number":["P01 R01ES032202"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01ES07821"],"award-info":[{"award-number":["R01ES07821"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","award":["RD83543601"],"award-info":[{"award-number":["RD83543601"]}],"id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["4150M9405"],"award-info":[{"award-number":["4150M9405"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013704","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda, Paraguay","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013704","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.envres.2023.116513","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T06:52:41Z","timestamp":1687935161000},"page":"116513","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Calcium supplementation and body mass index modify associations between prenatal phthalate exposure and perinatal bone ultrasound measures among pregnant women"],"prefix":"10.1016","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4562-7053","authenticated-orcid":false,"given":"Amber","family":"Cathey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7018-3602","authenticated-orcid":false,"given":"Marcela","family":"Tamayo-Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Tamayo-Orozco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8357-5085","authenticated-orcid":false,"given":"John D.","family":"Meeker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen E.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belem","family":"Trejo-Valdivia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha Maria","family":"T\u00e9llez-Rojo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah J.","family":"Watkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2023.116513_bib2","series-title":"Toxicological Profile for Di-n-butyl Phthalate","year":"2001"},{"key":"10.1016\/j.envres.2023.116513_bib3","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/nm.3159","article-title":"PPAR\u03b3 signaling and metabolism: the good, the bad and the future","volume":"19","author":"Ahmadian","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.envres.2023.116513_bib4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00018-013-1440-z","article-title":"Osteoblast-adipocyte lineage plasticity in tissue development, maintenance and pathology","volume":"71","author":"Berendsen","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.envres.2023.116513_bib5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.tiv.2012.09.003","article-title":"Di 2-ethyl hexyl phthalate affects differentiation and matrix mineralization of rat calvarial osteoblasts--in vitro","volume":"27","author":"Bhat","year":"2013","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.envres.2023.116513_bib6","doi-asserted-by":"crossref","first-page":"E3343","DOI":"10.1210\/clinem\/dgac228","article-title":"Serum PFAS and urinary phthalate biomarker concentrations and bone mineral density in 12-19 Year olds: 2011-2016 NHANES","volume":"107","author":"Carwile","year":"2022","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.envres.2023.116513_bib7","doi-asserted-by":"crossref","first-page":"169","DOI":"10.11005\/jbm.2019.26.3.169","article-title":"Effects of di(2-ethylhexyl)phthalate on bone metabolism in ovariectomized mice","volume":"26","author":"Choi","year":"2019","journal-title":"J. Bone Metab."},{"key":"10.1016\/j.envres.2023.116513_bib8","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1080\/13697130802178471","article-title":"The role of quantitative ultrasound in predicting osteoporosis defined by dual-energy X-ray absorptiometry in pre- and postmenopausal women","volume":"11","author":"Dane","year":"2008","journal-title":"Climacteric"},{"key":"10.1016\/j.envres.2023.116513_bib9","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1080\/09603123.2015.1111312","article-title":"Associations between bone mineral density and urinary phthalate metabolites among post-menopausal women: a cross-sectional study of NHANES data 2005-2010","volume":"26","author":"DeFlorio-Barker","year":"2016","journal-title":"Int. J. Environ. Health Res."},{"key":"10.1016\/j.envres.2023.116513_bib10","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s00404-009-1133-x","article-title":"Bone ultrasonometry measurements during pregnancy","volume":"281","author":"Della Martina","year":"2010","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.envres.2023.116513_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2891-13-116","article-title":"Effect of calcium supplementation on bone resorption in pregnancy and the early postpartum: a randomized controlled trial in Mexican Women","volume":"13","author":"Ettinger","year":"2014","journal-title":"Nutr. J."},{"key":"10.1016\/j.envres.2023.116513_bib12","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1289\/ehp.0800533","article-title":"Maternal arsenic exposure and impaired glucose tolerance during pregnancy","volume":"117","author":"Ettinger","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2023.116513_bib13","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1093\/toxsci\/58.2.350","article-title":"Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat","volume":"58","author":"Gray","year":"2000","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2023.116513_bib14","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1136\/oem.2004.017590","article-title":"Phthalates and human health","volume":"62","author":"Hauser","year":"2005","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.envres.2023.116513_bib15","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1080\/13697130601006048","article-title":"Quantitative ultrasonometry of the phalanges during pregnancy: a longitudinal study","volume":"9","author":"Hellmeyer","year":"2006","journal-title":"Climacteric"},{"key":"10.1016\/j.envres.2023.116513_bib16","first-page":"1","article-title":"Antagonistic effects of a mixture of low-dose nonylphenol and Di-N-Butyl phthalate (monobutyl phthalate) on the sertoli cells and serum reproductive hormones in prepubertal male rats in vitro and in vivo","volume":"9","author":"Hu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2023.116513_bib17","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/toxsci\/kfg145","article-title":"Activation of PPARalpha and PPARgamma by environmental phthalate monoesters","volume":"74","author":"Hurst","year":"2003","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2023.116513_bib18","doi-asserted-by":"crossref","DOI":"10.1289\/EHP1178","article-title":"Urinary BPA and phthalate metabolite concentrations and plasma vitamin D levels in pregnant women: a repeated measures analysis","volume":"125","author":"Johns","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2023.116513_bib19","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1210\/jc.2016-2134","article-title":"Relationships between urinary phthalate metabolite and bisphenol A concentrations and vitamin D levels in U.S. Adults: national health and nutrition examination survey (NHANES), 2005-2010","volume":"101","author":"Johns","year":"2016","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.envres.2023.116513_bib20","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.bone.2016.03.016","article-title":"Estrogen receptors alpha and beta in bone","volume":"87","author":"Khalid","year":"2016","journal-title":"Bone"},{"key":"10.1016\/j.envres.2023.116513_bib21","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a031211","article-title":"Regulation of bone metabolism by sex steroids","volume":"8","author":"Khosla","year":"2018","journal-title":"Cold Spring Harb. Perspect Med."},{"key":"10.1016\/j.envres.2023.116513_bib22","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1152\/physrev.00027.2015","article-title":"Maternal mineral and bone metabolism during pregnancy, lactation, and post-weaning recovery","volume":"96","author":"Kovacs","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.envres.2023.116513_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2021.116251","article-title":"Associations of pregnancy phthalate concentrations and their mixture with early adolescent bone mineral content and density: the Health Outcomes and Measures of the Environment (HOME) study","volume":"154","author":"Kuiper","year":"2022","journal-title":"Bone"},{"key":"10.1016\/j.envres.2023.116513_bib24","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1016\/j.chemosphere.2013.08.038","article-title":"Predictors of urinary bisphenol A and phthalate metabolite concentrations in Mexican children","volume":"93","author":"Lewis","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2023.116513_bib25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1476-069X-11-21","article-title":"Serum concentrations of phthalate metabolites are related to abdominal fat distribution two years later in elderly women","volume":"11","author":"Lind","year":"2012","journal-title":"Environ. Health"},{"key":"10.1016\/j.envres.2023.116513_bib26","doi-asserted-by":"crossref","first-page":"12711","DOI":"10.1007\/s11356-015-4567-7","article-title":"DEHP reduces thyroid hormones via interacting with hormone synthesis-related proteins, deiodinases, transthyretin, receptors, and hepatic enzymes in rats","volume":"22","author":"Liu","year":"2015","journal-title":"Environ. Sci. Pollut. Control Ser."},{"key":"10.1016\/j.envres.2023.116513_bib27","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1289\/ehp.0800522","article-title":"Urinary phthalate metabolites in relation to preterm birth in Mexico City","volume":"117","author":"Meeker","year":"2009","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2023.116513_bib28","doi-asserted-by":"crossref","first-page":"E1997","DOI":"10.1210\/jc.2014-2279","article-title":"Urinary phthalate metabolites and the risk of low bone mineral density and osteoporosis in older women","volume":"99","author":"Mi","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.envres.2023.116513_bib29","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000067935","article-title":"Pattern of bone markers during pregnancy and their changes after delivery","volume":"59","author":"Paoletti","year":"2003","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.envres.2023.116513_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmjopen-2019-030427","article-title":"Early life exposure in Mexico to ENvironmental Toxicants (ELEMENT) project","volume":"9","author":"Perng","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.envres.2023.116513_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.04.040","article-title":"Phthalate exposure and metabolic effects: a systematic review of the human epidemiological evidence","volume":"132","author":"Radke","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2023.116513_bib32","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222413662","article-title":"Obesity and bone: a complex relationship","volume":"22","author":"Rinonapoli","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envres.2023.116513_bib33","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.jocd.2013.11.002","article-title":"Bone speed of sound throughout lifetime assessed with quantitative ultrasound in a Mexican population","volume":"18","author":"Rivas-Ruiz","year":"2015","journal-title":"J. Clin. Densitometry"},{"key":"10.1016\/j.envres.2023.116513_bib34","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1007\/s00018-012-1211-2","article-title":"The interrelationship between bone and fat: from cellular see-saw to endocrine reciprocity","volume":"70","author":"Sadie-Van Gijsen","year":"2013","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.envres.2023.116513_bib35","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ando.2016.04.004","article-title":"Bone metabolism during pregnancy","volume":"77","author":"Salles","year":"2016","journal-title":"Ann. Endocrinol."},{"key":"10.1016\/j.envres.2023.116513_bib36","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1365-2605.2005.00567.x","article-title":"Human exposure to phthalates via consumer products","volume":"29","author":"Schettler","year":"2006","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.envres.2023.116513_bib37","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.tox.2004.11.013","article-title":"Evaluation of anti-androgenic activity of di-(2-ethylhexyl)phthalate","volume":"208","author":"Stroheker","year":"2005","journal-title":"Toxicology"},{"key":"10.1016\/j.envres.2023.116513_bib38","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.mce.2017.06.008","article-title":"Vitamin D endocrinology of bone mineralization","volume":"453","author":"van Driel","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2023.116513_bib39","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1002\/etc.2261","article-title":"Endocrine disruption by di-(2-ethylhexyl)-phthalate in Chinese rare minnow (Gobiocypris rarus)","volume":"32","author":"Wang","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.envres.2023.116513_bib40","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/63.3.433","article-title":"Putting body weight and osteoporosis into perspective","volume":"63","author":"Wardlaw","year":"1996","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envres.2023.116513_bib41","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1359\/jbmr.080810","article-title":"Bone structure and volumetric BMD in overweight children: a longitudinal study","volume":"23","author":"Wetzsteon","year":"2008","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.envres.2023.116513_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0092465","article-title":"Thyroid endocrine disruption in zebrafish larvae after exposure to mono-(2-ethylhexyl) phthalate (MEHP)","volume":"9","author":"Zhai","year":"2014","journal-title":"PLoS One"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935123013178?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935123013178?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T06:23:24Z","timestamp":1740723804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935123013178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":41,"alternative-id":["S0013935123013178"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2023.116513","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Calcium supplementation and body mass index modify associations between prenatal phthalate exposure and perinatal bone ultrasound measures among pregnant women","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2023.116513","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116513"}}