{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:51:15Z","timestamp":1792162275774,"version":"4.4.0"},"reference-count":88,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.envres.2024.118365","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T11:48:20Z","timestamp":1706615300000},"page":"118365","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Predictive statistical models for monitoring antimicrobial resistance spread in the environment using Apis mellifera (L. 1758) colonies"],"prefix":"10.1016","volume":"248","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5188-2864","authenticated-orcid":false,"given":"Ilaria","family":"Resci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4200-6043","authenticated-orcid":false,"given":"Laura","family":"Zavatta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Piva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Mondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4292-2199","authenticated-orcid":false,"given":"Sergio","family":"Albertazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Nanetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bortolotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5234-1240","authenticated-orcid":false,"given":"Giovanni","family":"Cilia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2024.118365_bib1","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1093\/jme\/tjw005","article-title":"Conjugation-mediated transfer of antibiotic-resistance plasmids between Enterobacteriaceae in the digestive tract of Blaberus craniifer (Blattodea: blaberidae)","volume":"53","author":"Anacarso","year":"2016","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.envres.2024.118365_bib2","article-title":"Potential environmental and human health risks caused by antibiotic-resistant bacteria (ARB), antibiotic resistance genes (ARGs) and emerging contaminants (ECs) from municipal solid waste (MSW) landfill","volume":"10, 374","author":"Anand","year":"2021","journal-title":"Antibiot"},{"key":"10.1016\/j.envres.2024.118365_bib3","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00040-011-0194-6","article-title":"An emerging paradigm of colony health: microbial balance of the honey bee and hive (Apis mellifera)","volume":"58","author":"Anderson","year":"2011","journal-title":"Insectes Soc."},{"key":"10.1016\/j.envres.2024.118365_bib4","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1007\/s00248-015-0716-2","article-title":"Ecological succession in the honey bee gut: shift in Lactobacillus strain Dominance during early adult development","volume":"71","author":"Anderson","year":"2016","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.envres.2024.118365_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jksus.2020.101247","article-title":"Honey bee gut an unexpected niche of human pathogen","volume":"33","author":"Anjum","year":"2021","journal-title":"J. King Saud Univ. Sci."},{"key":"10.1016\/j.envres.2024.118365_bib6","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.00176-21","article-title":"Honeybee exposure to veterinary drugs: how is the gut microbiota affected?","volume":"9","author":"Baffoni","year":"2021","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.envres.2024.118365_bib7","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s00244-007-9126-x","article-title":"Bee honey as an environmental bioindicator of pesticides' occurrence in six agricultural areas of Greece","volume":"55","author":"Balayiannis","year":"2008","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envres.2024.118365_bib8","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1080\/10643389.2015.1078220","article-title":"Honey bees and their products: bioindicators of environmental contamination","volume":"46","author":"Barga\u0144ska","year":"2016","journal-title":"Crit. Rev. Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.118365_bib9","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1093\/jme\/tjz086","article-title":"An examination of flying insects in seven hospitals in the United Kingdom and carriage of bacteria by true flies (Diptera: calliphoridae, dolichopodidae, fanniidae, muscidae, phoridae, psychodidae, sphaeroceridae)","volume":"56","author":"Boiocchi","year":"2019","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.envres.2024.118365_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2021.e06194","article-title":"Disentangling multiple PM emission sources in the Po Valley (Italy) using honey bees","volume":"7","author":"Capitani","year":"2021","journal-title":"Heliyon"},{"key":"10.1016\/j.envres.2024.118365_bib11","first-page":"137","article-title":"Honey bees as bioindicators of environmental pollution","volume":"56","author":"Celli","year":"2003","journal-title":"Bull. Insectol."},{"key":"10.1016\/j.envres.2024.118365_bib12","doi-asserted-by":"crossref","first-page":"9637","DOI":"10.1007\/s11356-020-07629-3","article-title":"Cross-sectional study to identify risk factors associated with the occurrence of antimicrobial resistance genes in honey bees Apis mellifera) in Umbria, Central Italy","volume":"27","author":"Cenci-Goga","year":"2020","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.envres.2024.118365_bib13","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.tvjl.2005.01.004","article-title":"Antimicrobial resistance of Providencia spp. isolated from animal manure","volume":"172","author":"Chander","year":"2006","journal-title":"Vet. J."},{"key":"10.1016\/j.envres.2024.118365_bib14","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s00239-019-09914-3","article-title":"Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence","volume":"88","author":"Christaki","year":"2019","journal-title":"J. Mol. Evol."},{"key":"10.1016\/j.envres.2024.118365_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150327","article-title":"Honey bee (Apis mellifera L.) colonies as bioindicators of environmental SARS-CoV-2 occurrence","volume":"805","author":"Cilia","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.118365_bib16","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1080\/00218839.2020.1830259","article-title":"Changes of Western honey bee Apis mellifera ligustica (Spinola, 1806) ventriculus microbial profile related to their in-hive tasks","volume":"60","author":"Cilia","year":"2021","journal-title":"J. Apicult. Res."},{"key":"10.1016\/j.envres.2024.118365_bib17","first-page":"76","article-title":"Microbial profile of the ventriculum of honey bee (Apis mellifera ligustica spinola, 1806) fed with veterinary drugs, dietary supplements and non-protein amino acids","volume":"7","author":"Cilia","year":"2020","journal-title":"Vet. Sci."},{"key":"10.1016\/j.envres.2024.118365_bib18","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/5540574","article-title":"Antimicrobial-resistant environmental bacteria isolated using a network of honey bee colonies (Apis mellifera L. 1758)","volume":"2023","author":"Cilia","year":"2023","journal-title":"Transbound. Emerg. Dis."},{"key":"10.1016\/j.envres.2024.118365_bib19","series-title":"M100Ed32 | Performance Standards for Antimicrobial Susceptibility Testing","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib20","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1023\/A:1010719107006","article-title":"Honeybees and their products as potential bioindicators of heavy metals contamination","volume":"69","author":"Conti","year":"2001","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.envres.2024.118365_bib21","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/nrmicro2265","article-title":"Molecular mechanisms of Escherichia coli pathogenicity","volume":"8","author":"Croxen","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib22","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1007\/s00248-015-0720-6","article-title":"Significance and roles of Proteus spp. bacteria in natural environments","volume":"72","author":"Drzewiecka","year":"2016","journal-title":"Microb. Ecol."},{"key":"10.1016\/j.envres.2024.118365_bib23","first-page":"51","article-title":"Isolation and antibiotic resistance patterns of Escherichia coli and coagulase positive Staphylococcus aureus from the digestive tract of honey bees. Iran","volume":"6","author":"Ebrahimi","year":"2005","journal-title":"J. Vet. Res."},{"key":"10.1016\/j.envres.2024.118365_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.144481","article-title":"Honeybees as active samplers for microplastics","volume":"767","author":"Edo","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.118365_bib25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/978-3-031-23796-6_12","article-title":"The use of nanomaterials for the elimination of antibiotic-resistant bacteria from water and wastewater: an African overview","author":"El-Liethy","year":"2023","journal-title":"Antimicrob. Res. One Heal. Afr."},{"key":"10.1016\/j.envres.2024.118365_bib26","series-title":"Breakpoint Tables for Interpretation of MICs and Zone Diameters","year":"2023"},{"key":"10.1016\/j.envres.2024.118365_bib27","series-title":"Car: Companion to Applied Regression","author":"Fox","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib28","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1089\/mdr.2017.0371","article-title":"Role of Flies in the Maintenance of Antimicrobial Resistance in Farm Environments","volume":"25","author":"Fukuda","year":"2019","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.envres.2024.118365_bib29","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1089\/mdr.2015.0125","article-title":"Horizontal Transfer of Plasmid-Mediated Cephalosporin Resistance Genes in the Intestine of Houseflies (Musca domestica)","volume":"22","author":"Fukuda","year":"2016","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.envres.2024.118365_bib30","doi-asserted-by":"crossref","first-page":"7206","DOI":"10.1021\/jf060823t","article-title":"Preliminary chemometric study on the use of honey as an environmental marker in Galicia (northwestern Spain)","volume":"54","author":"Garc\u00eda","year":"2006","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.envres.2024.118365_bib31","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/s00244-003-3219-y","article-title":"Occurrence and Distribution of Pesticides in the Province of Bologna, Italy, Using Honeybees as Bioindicators","volume":"47","author":"Ghini","year":"2004","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envres.2024.118365_bib32","first-page":"69","article-title":"Use of honeybees (Apis mellifera L.) as indicators of the presence of the phytopathogenic bacteria Erwinia amylovora","volume":"4","author":"Ghini","year":"2002","journal-title":"Insect Soc. Life"},{"key":"10.1016\/j.envres.2024.118365_bib33","first-page":"284","article-title":"Report on a project: BeeNet at the start","volume":"74","author":"Giovanetti","year":"2021","journal-title":"Bull. Insectol."},{"issue":"256","key":"10.1016\/j.envres.2024.118365_bib34","article-title":"Genetics of acquired antibiotic resistance genes in Proteus spp","volume":"11","author":"Girlich","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib35","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s41207-020-00204-9","article-title":"Bioindicators and biomonitoring: honeybees and hive products as pollution impact assessment tools for the Mediterranean area","volume":"5","author":"Girotti","year":"2020","journal-title":"Euro-Mediterranean J. Environ. Integr."},{"key":"10.1016\/j.envres.2024.118365_bib36","doi-asserted-by":"crossref","DOI":"10.1007\/s00216-012-6443-3","article-title":"Trace analysis of pollutants by use of honeybees, immunoassays, and chemiluminescence detection","author":"Girotti","year":"2013","journal-title":"Anal. Bioanal. Chem. 405:555-571"},{"key":"10.1016\/j.envres.2024.118365_bib37","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1139\/er-2017-0029","article-title":"The use of honeybees and honey as environmental bioindicators for metals and radionuclides: a review","volume":"25","author":"Herrero-Latorre","year":"2017","journal-title":"Environ. Rev."},{"key":"10.1016\/j.envres.2024.118365_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118707","article-title":"Variation in honey bee gut microbial diversity affected by ontogenetic stage, age and geographic location","volume":"10","author":"Hroncova","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2024.118365_bib39","series-title":"An Introduction to Statistical Learning with Application in R","author":"James","year":"2014"},{"key":"10.1016\/j.envres.2024.118365_bib40","doi-asserted-by":"crossref","first-page":"9533","DOI":"10.1007\/s11356-021-17773-z","article-title":"Occurrence and spread of antibiotic-resistant bacteria on animal farms and in their vicinity in Poland and Ukraine-review","volume":"29","author":"Je\u017cak","year":"2022","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.envres.2024.118365_bib41","series-title":"Caret: Classification and Regression Training","author":"Kuhn","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib42","doi-asserted-by":"crossref","DOI":"10.1098\/rsos.170003","article-title":"Immune system stimulation by the native gut microbiota of honey bees","volume":"4","author":"Kwong","year":"2017","journal-title":"R. Soc. Open Sci."},{"key":"10.1016\/j.envres.2024.118365_bib43","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/nrmicro.2016.43","article-title":"Gut microbial communities of social bees","volume":"14","author":"Kwong","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib44","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1099\/ijs.0.044875-0","article-title":"Cultivation and characterization of the gut symbionts of honey bees and bumble bees: description of Snodgrassella alvi gen. nov., sp. nov., a member of the family Neisseriaceae of the betaproteobacteria, and Gilliamella apicola gen. nov., sp. nov., a memb","volume":"63","author":"Kwong","year":"2013","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.151131","article-title":"Beehive products as bioindicators of antimicrobial resistance contamination in the environment","volume":"823","author":"Laconi","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.118365_bib46","doi-asserted-by":"crossref","first-page":"156544","DOI":"10.1016\/j.scitotenv.2022.156544","article-title":"Antibiotic resistant bacteria and genes in wastewater treatment plants: from occurrence to treatment strategies","volume":"838,","author":"Li","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.118365_bib47","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1038\/s41559-022-01840-w","article-title":"The gut microbiota affects the social network of honeybees","volume":"6","author":"Liberti","year":"2022","journal-title":"Nat. Ecol. Evol."},{"key":"10.1016\/j.envres.2024.118365_bib48","series-title":"sjPlot: Data Visualization for Statistics in Social Science","author":"L\u00fcdecke","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib49","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s00248-018-1171-7","article-title":"Detection and characterization of streptomycin resistance (strA-strB) in a honeybee gut symbiont (snodgrassella alvi) and the associated risk of antibiotic resistance transfer","volume":"76","author":"Ludvigsen","year":"2018","journal-title":"Microb. Ecol."},{"issue":"795","key":"10.1016\/j.envres.2024.118365_bib50","article-title":"Antibiotic use in agriculture and its consequential resistance in environmental sources: potential public health implications","volume":"23,","author":"Manyi-Loh","year":"2018","journal-title":"Mol"},{"key":"10.1016\/j.envres.2024.118365_bib51","doi-asserted-by":"crossref","first-page":"1193907","DOI":"10.3389\/fmicb.2023.1193907","article-title":"Wastewater treatment plants, an \u201cescape gate\u201d for ESCAPE pathogens","volume":"14,","author":"Marutescu","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib52","article-title":"Microbial source tracking and antimicrobial resistance in one river system of a rural community in Bahia, Brazil","volume":"82","author":"Moretto","year":"2021","journal-title":"Braz. J. Biol."},{"key":"10.1016\/j.envres.2024.118365_bib53","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1007\/s13592-020-00779-w","article-title":"Differences in honey bee bacterial diversity and composition in agricultural and pristine environments \u2013 a field study","volume":"51","author":"Mu\u00f1oz-Colmenero","year":"2020","journal-title":"Apidologie"},{"key":"10.1016\/j.envres.2024.118365_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132491","article-title":"Honey bees (Apis mellifera, L.) as active samplers of airborne particulate matter","volume":"10","author":"Negri","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2024.118365_bib55","doi-asserted-by":"crossref","first-page":"113067","DOI":"10.1016\/j.envpol.2019.113067","article-title":"Freshwater environments as reservoirs of antibiotic resistant bacteria and their role in the dissemination of antibiotic resistance genes","volume":"254","author":"Nnadozie","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.118365_bib56","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.5322","article-title":"Particulate matter collection by honey bees (Apis mellifera, L.) near to a cement factory in Italy","volume":"6","author":"Pellecchia","year":"2018","journal-title":"Peer J."},{"key":"10.1016\/j.envres.2024.118365_bib57","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1007\/s12011-010-8688-z","article-title":"Heavy metal (Hg, Cr, Cd, and Pb) contamination in urban areas and wildlife reserves: honeybees as bioindicators","volume":"140","author":"Perugini","year":"2011","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.envres.2024.118365_bib58","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1093\/jmedent\/43.2.288","article-title":"Horizontal transfer of shiga toxin and antibiotic resistance genes among Escherichia coli strains in house fly (Diptera: muscidae) gut","volume":"43","author":"Petridis","year":"2006","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.envres.2024.118365_bib59","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/lam.13288","article-title":"Could honey bees signal the spread of antimicrobial resistance in the environment?","volume":"70","author":"Piva","year":"2020","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib60","first-page":"137","article-title":"Using honey bee as bioindicator of chemicals in Campanian agroecosystems (South Italy)","volume":"67","author":"Porrini","year":"2014","journal-title":"Bull. Insectol."},{"key":"10.1016\/j.envres.2024.118365_bib61","first-page":"147","article-title":"The death of honey bees and environmental pollution by pesticides: the honey bees as biological indicators","volume":"56","author":"Porrini","year":"2003","journal-title":"Bull. Insectol."},{"key":"10.1016\/j.envres.2024.118365_bib62","doi-asserted-by":"crossref","first-page":"7378","DOI":"10.1128\/AEM.01861-14","article-title":"Routes of acquisition of the gut microbiota of the honey bee Apis mellifera","volume":"80","author":"Powell","year":"2014","journal-title":"Appl. Environ."},{"key":"10.1016\/j.envres.2024.118365_bib63","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1093\/jac\/dkw231","article-title":"A review of the pharmacokinetics and pharmacodynamics of aztreonam","volume":"71","author":"Ramsey","year":"2016","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.envres.2024.118365_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.122120","article-title":"The use of honey bee (Apis mellifera L .) as biological monitors for pathogenic bacteria and antimicrobial resistance : a systematic review","volume":"333","author":"Resci","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.118365_bib65","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/j.foodchem.2005.10.034","article-title":"Multiresidue determination of pesticides in honey samples by gas chromatography-mass spectrometry and application in environmental contamination","volume":"101","author":"Rissato","year":"2007","journal-title":"Food Chem."},{"key":"10.1016\/j.envres.2024.118365_bib66","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s12011-013-9732-6","article-title":"Biomonitoring with honeybees of heavy metals and pesticides in nature reserves of the Marche region (Italy)","volume":"154","author":"Ruschioni","year":"2013","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.envres.2024.118365_bib67","series-title":"Quantmod: Quantitative Financial Modelling Framework","author":"Ryan","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib68","doi-asserted-by":"crossref","first-page":"155","DOI":"10.17660\/ActaHortic.2006.704.19","article-title":"Relationships between Apis mellifera and Erwinia amylovora: bioindication, bacterium dispersal and quarantine procedures","volume":"704","author":"Sabatini","year":"2006","journal-title":"Acta Hortic."},{"key":"10.1016\/j.envres.2024.118365_bib69","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.UTI-0017-2013","article-title":"Proteus mirabilis and urinary tract infections","volume":"3","author":"Schaffer","year":"2015","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.envres.2024.118365_bib70","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.vetmic.2004.11.017","article-title":"Comparison of vancomycin-resistant enterococci isolates from human, poultry and pigs in Korea","volume":"106","author":"Seo","year":"2005","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib71","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1111\/jam.13553","article-title":"Prudent use and regulatory guidelines for veterinary antibiotics\u2014politics or science?","volume":"123","author":"Silley","year":"2017","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0226101","article-title":"Significant reduction of vancomycin resistant E. Faecium in the Norwegian broiler population coincided with measures taken by the broiler industry to reduce antimicrobial resistant bacteria","volume":"14","author":"Simm","year":"2019","journal-title":"PLoS One"},{"issue":"943\u2013952","key":"10.1016\/j.envres.2024.118365_bib73","article-title":"Can landscape ecology untangle the complexity of antibiotic resistance?","volume":"4","author":"Singer","year":"2006","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib74","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1637\/7197-042004R","article-title":"Prevalence of vancomycin resistant enterococci on poultry farms established after the ban of avoparcin","volume":"48","author":"S\u00f8rum","year":"2004","journal-title":"Avian Dis."},{"key":"10.1016\/j.envres.2024.118365_bib75","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/B978-0-12-800261-2.00004-9","article-title":"Environmental and animal-associated enterococci","volume":"87","author":"Staley","year":"2014","journal-title":"Adv. Appl. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib76","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrmicro2298","article-title":"The population genetics of commensal Escherichia coli","volume":"8","author":"Tenaillon","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.envres.2024.118365_bib77","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00377-12","article-title":"Long-term exposure to antibiotics has caused accumulation of resistance determinants in the gut microbiota of honeybees","volume":"3","author":"Tian","year":"2012","journal-title":"mBio"},{"key":"10.1016\/j.envres.2024.118365_bib78","series-title":"caTools: Tools: Moving Window Statistics, GIF, Base64","author":"Tuszynski","year":"2022"},{"key":"10.1016\/j.envres.2024.118365_bib79","doi-asserted-by":"crossref","first-page":"4119","DOI":"10.1007\/s10661-011-2248-7","article-title":"Spatial and temporal variation of metal concentrations in adult honeybees (Apis mellifera L.)","volume":"184","author":"van der Steen","year":"2012","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.envres.2024.118365_bib80","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10661-016-5451-8","article-title":"Think regionally, act locally: metals in honeybee workers in The Netherlands (surveillance study 2008)","volume":"188","author":"van der Steen","year":"2016","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.envres.2024.118365_bib81","series-title":"Modern Applied Statistics with S, Statistics and Computing","author":"Venables","year":"2002"},{"key":"10.1016\/j.envres.2024.118365_bib82","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abd3431","article-title":"The gut microbiome defines social group membership in honey bee colonies","volume":"6","author":"Vernier","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.envres.2024.118365_bib83","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1749-6632.2010.05861.x","article-title":"Production of antibiotic substances by actinomycetes","volume":"1213","author":"Waksman","year":"2010","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.envres.2024.118365_bib84","series-title":"Dplyr: A Grammar of Data Manipulation","author":"Wickham","year":"2023"},{"key":"10.1016\/j.envres.2024.118365_bib85","series-title":"ggplot2: Elegant Graphics for Data Analysis, Ggplot2","author":"Wickham","year":"2009"},{"key":"10.1016\/j.envres.2024.118365_bib86","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1159\/000514097","article-title":"Pathogenesis of Proteus mirabilis in catheter-associated urinary tract infections","volume":"105","author":"Yuan","year":"2021","journal-title":"Urol. Int."},{"key":"10.1016\/j.envres.2024.118365_bib87","article-title":"Genomic insights into antibiotic-resistance and virulence genes of Enterococcus faecium strains from the gut of Apis mellifera","volume":"8","author":"Zaghloul","year":"2022","journal-title":"Microb. Genom."},{"key":"10.1016\/j.envres.2024.118365_bib88","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.610656","article-title":"Antibiotics and antibiotic resistance genes in animal manure \u2013 consequences of its application in agriculture","volume":"12","author":"Zalewska","year":"2021","journal-title":"Front. Microbiol."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512400269X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512400269X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T03:18:00Z","timestamp":1762139880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001393512400269X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":88,"alternative-id":["S001393512400269X"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2024.118365","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive statistical models for monitoring antimicrobial resistance spread in the environment using Apis mellifera (L. 1758) colonies","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2024.118365","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"118365"}}