{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T10:40:50Z","timestamp":1775904050802,"version":"3.50.1"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42277374"],"award-info":[{"award-number":["42277374"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.envres.2024.118930","type":"journal-article","created":{"date-parts":[[2024,4,13]],"date-time":"2024-04-13T01:47:45Z","timestamp":1712972865000},"page":"118930","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"P3","title":["Fish skin mucosal surface becomes a barrier of antibiotic resistance genes under apramycin exposure"],"prefix":"10.1016","volume":"252","author":[{"given":"Wenpeng","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohan","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Xin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongzheng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3813-2044","authenticated-orcid":false,"given":"Zhiguang","family":"Niu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2024.118930_bib1","first-page":"42","article-title":"Determination of antibiotic consumption index for animal originated foods produced in animal husbandry in Iran, 2010","volume":"12","author":"Aalipour","year":"2014","journal-title":"J. Environ. Health Sci."},{"issue":"4","key":"10.1016\/j.envres.2024.118930_bib2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrmicro2312","article-title":"Call of the wild: antibiotic resistance genes in natural environments","volume":"8","author":"Allen","year":"2010","journal-title":"Nat. Rev. Microbiol."},{"issue":"2","key":"10.1016\/j.envres.2024.118930_bib3","doi-asserted-by":"crossref","first-page":"8517","DOI":"10.7717\/peerj.8517","article-title":"Microbial communities on fish eggs from Acanthopagrus schlegelii and Halichoeres nigrescens at the XuWen coral reef in the Gulf of Tonkin","volume":"8","author":"Bai","year":"2020","journal-title":"PeerJ"},{"key":"10.1016\/j.envres.2024.118930_bib4","article-title":"Behavioral impairment and neurotoxic responses of silver catfish Rhamdia quelen exposed to organophosphate pesticide trichlorfon: protective effects of diet containing rutin","volume":"239","author":"Baldissera","year":"2021","journal-title":"Comp. Biochem. Phys. C."},{"issue":"6304","key":"10.1016\/j.envres.2024.118930_bib5","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1126\/science.aag0822","article-title":"Spatiotemporal microbial evolution on antibiotic landscapes","volume":"353","author":"Baym","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.envres.2024.118930_bib6","article-title":"Acute toxicity and sublethal effects of sodium laureth sulfate on oxidative stress enzymes in benthic oligochaete worm, Tubifex tubifex","volume":"243","author":"Bhattacharya","year":"2021","journal-title":"Comp. Biochem. Phys. C."},{"issue":"15","key":"10.1016\/j.envres.2024.118930_bib7","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.envres.2024.118930_bib8","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/raq.12786","article-title":"Review of alternatives to antibiotic use in aquaculture","volume":"15","author":"Bondad-Reantaso","year":"2023","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.envres.2024.118930_bib9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jprot.2018.08.002","article-title":"Combined proteomic and functional analysis reveals rich sources of protein diversity in skin mucus and venom from the Scorpaena plumieri fish","volume":"187","author":"Borges","year":"2018","journal-title":"J. Proteonomics"},{"issue":"3","key":"10.1016\/j.envres.2024.118930_bib10","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/s41579-018-0129-6","article-title":"Fusobacterium nucleatum - symbiont, opportunist and oncobacterium","volume":"17","author":"Brennan","year":"2019","journal-title":"Nat. Rev. Microbiol."},{"issue":"6369","key":"10.1016\/j.envres.2024.118930_bib11","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1126\/science.aal5240","article-title":"Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer","volume":"358","author":"Bullman","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.envres.2024.118930_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.125761","article-title":"Compartmentation of microbial communities in structure and function for methane oxidation coupled to nitrification-denitrification","volume":"341","author":"Cao","year":"2021","journal-title":"Bioresour. Technol."},{"issue":"2","key":"10.1016\/j.envres.2024.118930_bib53","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.addr.2008.09.008","article-title":"Barrier properties of mucus","volume":"61","author":"Cone","year":"2009","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.envres.2024.118930_bib13","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/jfd.12373","article-title":"Mucoadhesive nanoparticles: a new perspective for fish drug application","volume":"39","author":"Costa","year":"2016","journal-title":"J. Fish. Dis."},{"issue":"6","key":"10.1016\/j.envres.2024.118930_bib14","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1086\/422997","article-title":"Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection","volume":"39","author":"Davis","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.envres.2024.118930_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.133948","article-title":"The accumulation of microplastics in fish from an important fish farm and mariculture area, Haizhou Bay, China","volume":"696","author":"Feng","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.118930_bib16","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.scitotenv.2018.07.083","article-title":"Skin mucus metabolites in response to physiological challenges: a valuable non-invasive method to study teleost marine species","volume":"644","author":"Fern\u00e1ndez-Alacid","year":"2018","journal-title":"Sci. Total Environ."},{"issue":"7502","key":"10.1016\/j.envres.2024.118930_bib17","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/nature13377","article-title":"Bacterial phylogeny structures soil resistomes across habitats","volume":"509","author":"Forsberg","year":"2014","journal-title":"Nature"},{"issue":"19","key":"10.1016\/j.envres.2024.118930_bib18","doi-asserted-by":"crossref","first-page":"5318","DOI":"10.1111\/mec.14255","article-title":"Aquatic animals promote antibiotic resistance gene dissemination in water via conjugation: role of different regions within the zebra fish intestinal tract, and impact on fish intestinal microbiota","volume":"26","author":"Fu","year":"2017","journal-title":"Mol. Ecol."},{"issue":"9","key":"10.1016\/j.envres.2024.118930_bib19","doi-asserted-by":"crossref","first-page":"5598","DOI":"10.1128\/AEM.71.9.5598-5600.2005","article-title":"Isolation of multidrug-resistant Stenotrophomonas maltophilia from cultured yellowtail (Seriola quinqueradiata) from a marine fish farm","volume":"71","author":"Furushita","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"issue":"7","key":"10.1016\/j.envres.2024.118930_bib20","doi-asserted-by":"crossref","first-page":"2355","DOI":"10.1016\/j.watres.2012.02.004","article-title":"Occurrence of sulfonamide and tetracycline-resistant bacteria and resistance genes in aquaculture environment","volume":"46","author":"Gao","year":"2012","journal-title":"Water Res."},{"key":"10.1016\/j.envres.2024.118930_bib21","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.fsi.2016.11.025","article-title":"Terminal carbohydrates abundance, immune related enzymes, bactericidal activity and physico-chemical parameters of the Senegalese sole (Solea senegalensis, Kaup) skin mucus","volume":"60","author":"Guardiola","year":"2017","journal-title":"Fish Shellfish Immunol."},{"issue":"2","key":"10.1016\/j.envres.2024.118930_bib22","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.fsi.2014.01.001","article-title":"Comparative skin mucus and serum humoral defence mechanisms in the teleost gilthead seabream (Sparus aurata)","volume":"36","author":"Guardiola","year":"2014","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envres.2024.118930_bib23","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.fsi.2018.08.057","article-title":"beta-1, 3 glucan binding protein based selenium nanowire enhances the immune status of Cyprinus carpio and protection against Aeromonas hydrophila infection","volume":"83","author":"Iswarya","year":"2018","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envres.2024.118930_bib24","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.envpol.2017.10.006","article-title":"Prevalence of antibiotic resistance genes from effluent of coastal aquaculture, South Korea","volume":"233","author":"Jang","year":"2018","journal-title":"Environ. Pollut."},{"issue":"4","key":"10.1016\/j.envres.2024.118930_bib25","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1111\/j.1095-8649.2011.02922.x","article-title":"Cellular responses in the skin of the gilthead sea bream Sparus aurata L. and the sea bass Dicentrarchus labrax (L.) exposed to high ammonia","volume":"78","author":"Kalogianni","year":"2011","journal-title":"J. Fish Biol."},{"key":"10.1016\/j.envres.2024.118930_bib26","first-page":"61","article-title":"The survey of antibiotic resistance in gram negative bacilli, isolated from Urine culture specimens, Kermanshah Imam Reza Hospital","volume":"41","author":"Khazaei","year":"2010","journal-title":"Pathology"},{"issue":"7","key":"10.1016\/j.envres.2024.118930_bib27","doi-asserted-by":"crossref","first-page":"4190","DOI":"10.1021\/acs.est.9b07600","article-title":"Tissue distribution of several series of cationic surfactants in rainbow trout (Oncorhynchus mykiss) following exposure via water","volume":"54","author":"Kierkegaard","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.118930_bib28","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.fsi.2020.08.028","article-title":"L-Amino acid oxidase as a fish host-defense molecule","volume":"106","author":"Kitani","year":"2020","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envres.2024.118930_bib29","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.fsi.2019.03.053","article-title":"Biology, environmental and nutritional modulation of skin mucus alkaline phosphatase in fish: a review","volume":"89","author":"Lalles","year":"2019","journal-title":"Fish Shellfish Immunol."},{"issue":"12","key":"10.1016\/j.envres.2024.118930_bib30","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/jfd.12479","article-title":"Interactions between candidate probiotics and the immune and antioxidative responses of European sea bass (Dicentrarchus labrax) larvae","volume":"39","author":"Lamari","year":"2016","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.envres.2024.118930_bib31","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.aquatox.2014.07.011","article-title":"Microcystin-LR exposure to adult zebrafish (Danio rerio) leads to growth inhibition and immune dysfunction in F1 offspring, a parental transmission effect of toxicity","volume":"155","author":"Liu","year":"2014","journal-title":"Aquat. Toxicol."},{"issue":"19","key":"10.1016\/j.envres.2024.118930_bib32","doi-asserted-by":"crossref","first-page":"7220","DOI":"10.1021\/es100233w","article-title":"Trends in antibiotic resistance genes occurrence in the Haihe River, China","volume":"44","author":"Luo","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.118930_bib33","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.3389\/fmicb.2016.02137","article-title":"The resistome of farmed fish feces contributes to the enrichment of antibiotic resistance genes in sediments below Baltic Sea fish farms","volume":"7","author":"Muziasari","year":"2017","journal-title":"Front. Microbiol."},{"issue":"3","key":"10.1016\/j.envres.2024.118930_bib34","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s10695-013-9872-9","article-title":"Characterization of carboxylesterase in skin mucus of Cirrhinus mrigala and its assessment as biomarker of organophosphate exposure","volume":"40","author":"Nigam","year":"2014","journal-title":"Fish Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.envres.2024.118930_bib35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.marpolbul.2016.03.064","article-title":"Occurrence and distribution of antibiotic resistance genes in the coastal area of the Bohai Bay, China","volume":"107","author":"Niu","year":"2016","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.envres.2024.118930_bib36","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.3389\/fmicb.2020.01764","article-title":"Tetracycline resistance gene profiles in Red Seabream (Pagrus major) intestine and rearing water after Oxytetracycline administration","volume":"11","author":"Obayashi","year":"2020","journal-title":"Front. Microbiol."},{"issue":"23","key":"10.1016\/j.envres.2024.118930_bib37","doi-asserted-by":"crossref","first-page":"7445","DOI":"10.1021\/es060413l","article-title":"Antibiotic resistance genes as emerging contaminants: studies in northern Colorado","volume":"40","author":"Pruden","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.118930_bib38","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.fsi.2017.03.027","article-title":"Dietary yeast Sterigmatomyces halophilus enhances mucosal immunity of gilthead seabream (Sparus aurata L.)","volume":"64","author":"Reyes-Becerril","year":"2017","journal-title":"Fish Shellfish Immunol."},{"key":"10.1016\/j.envres.2024.118930_bib39","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.watres.2014.11.021","article-title":"Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river","volume":"69","author":"Rodriguez-Mozaz","year":"2015","journal-title":"Water Res."},{"key":"10.1016\/j.envres.2024.118930_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/science.aau4679","article-title":"The challenge of antimicrobial resistance: what economics can contribute","volume":"364","author":"Roope","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.envres.2024.118930_bib41","article-title":"Diazinon exposure produces histological damage, oxidative stress, immune disorders and gut microbiota dysbiosis in crucian carp (Carassius auratus gibelio)","volume":"269, 116129","author":"Tang","year":"2021","journal-title":"Environ. Pollut."},{"issue":"2","key":"10.1016\/j.envres.2024.118930_bib42","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S1382-6689(02)00126-6","article-title":"Fish bioaccumulation and biomarkers in environmental risk assessment: a review","volume":"13","author":"van der Oost","year":"2003","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"5","key":"10.1016\/j.envres.2024.118930_bib43","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S1473-3099(11)70059-7","article-title":"Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study","volume":"11","author":"Walsh","year":"2011","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.envres.2024.118930_bib44","doi-asserted-by":"crossref","first-page":"187","DOI":"10.12659\/MSMBR.883968","article-title":"A reliable and feasible qPCR strategy for titrating AAV vectors","volume":"19","author":"Wang","year":"2013","journal-title":"Med. Sci. Monit. Basic"},{"key":"10.1016\/j.envres.2024.118930_bib45","series-title":"Oxidation Stress Response and Ecological Risk Assessment for Zebra Fish Induced by Streptomycin Wastewater","author":"Wang","year":"2014"},{"issue":"10","key":"10.1016\/j.envres.2024.118930_bib46","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.3390\/biology11101523","article-title":"Selenium nanoparticle-enriched and potential probiotic, Lactiplantibacillus plantarum S14 strain, a diet supplement beneficial for rainbow trout","volume":"11","author":"Yanez-Lemus","year":"2022","journal-title":"Biology-Basel"},{"issue":"2","key":"10.1016\/j.envres.2024.118930_bib47","article-title":"Antibiotic resistance and microbiota in the gut of Chinese four major freshwater carp from retail markets","volume":"255","author":"Yuan","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.118930_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2019.734562","article-title":"Dietary mycotoxicosis prevention with modified zeolite (Clinoptilolite) feed additive in Nile tilapia (Oreochromis niloticus)","volume":"515","author":"Zahran","year":"2020","journal-title":"Aquaculture"},{"issue":"6","key":"10.1016\/j.envres.2024.118930_bib49","first-page":"2600","article-title":"Characteristics of antibiotic resistance genes in downstream areas of the Aojiang River, Fujian Province","volume":"39","author":"Zhang","year":"2018","journal-title":"Huanjing Kexue"},{"key":"10.1016\/j.envres.2024.118930_bib50","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.envpol.2017.11.031","article-title":"Distribution of ARGs and MGEs among glacial soil, permafrost, and sediment using metagenomic analysis","volume":"234","author":"Zhang","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.118930_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111517","article-title":"Large-scale pattern of resistance genes and bacterial community in the tap water along the middle and low reaches of the Yangtze River","volume":"208","author":"Zhang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512400834X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512400834X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T01:00:16Z","timestamp":1733965216000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001393512400834X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":52,"alternative-id":["S001393512400834X"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2024.118930","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fish skin mucosal surface becomes a barrier of antibiotic resistance genes under apramycin exposure","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2024.118930","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"118930"}}