{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:14:48Z","timestamp":1793121288958,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373614"],"award-info":[{"award-number":["82373614"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515010214"],"award-info":[{"award-number":["2022A1515010214"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012007","name":"Rockefeller University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012007","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021B1515140037"],"award-info":[{"award-number":["2021B1515140037"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["20231800935952"],"award-info":[{"award-number":["20231800935952"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.envres.2024.119159","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T21:29:11Z","timestamp":1715722151000},"page":"119159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Prenatal triphenyl phosphate exposure impairs placentation and induces preeclampsia-like symptoms in mice"],"prefix":"10.1016","volume":"257","author":[{"given":"Qian","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengzhu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiabin","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5813-0914","authenticated-orcid":false,"given":"Chun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanwen","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5291-642X","authenticated-orcid":false,"given":"Xiaoshan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.envres.2024.119159_bib1","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.chemosphere.2012.03.100","article-title":"Occurrence of alternative flame retardants in indoor dust from New Zealand: indoor sources and human exposure assessment","volume":"88","author":"Ali","year":"2012","journal-title":"Chemosphere"},{"issue":"6","key":"10.1016\/j.envres.2024.119159_bib63","doi-asserted-by":"crossref","first-page":"e237","DOI":"10.1097\/AOG.0000000000003891","article-title":"Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222","volume":"135","author":"American College of Obstetricians and Gynecologists (ACOG)","year":"2020","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.envres.2024.119159_bib2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1039\/C8EM00389K","article-title":"A pilot study of metabolites of organophosphorus flame retardants in paired maternal urine and amniotic fluid samples: potential exposure risks of tributyl phosphate to pregnant women","volume":"21","author":"Bai","year":"2019","journal-title":"Environmental science. Processes & impacts"},{"issue":"4","key":"10.1016\/j.envres.2024.119159_bib3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S1097-2765(00)80209-9","article-title":"PPAR gamma is required for placental, cardiac, and adipose tissue development","volume":"4","author":"Barak","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/j.envres.2024.119159_bib4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1477-7827-7-51","article-title":"Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line","volume":"7","author":"Butler","year":"2009","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.envres.2024.119159_bib5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.chemosphere.2017.03.076","article-title":"Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort)","volume":"179","author":"Castorina","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2024.119159_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.placenta.2019.05.002","article-title":"Downregulation of receptor tyrosine kinase-like orphan receptor 1 in preeclampsia placenta inhibits human trophoblast cell proliferation, migration, and invasion by PI3K\/AKT\/mTOR pathway accommodation","volume":"82","author":"Chen","year":"2019","journal-title":"Placenta"},{"key":"10.1016\/j.envres.2024.119159_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.145404","article-title":"Organophosphorus flame retardants in breast milk from Beijing, China: occurrence, nursing infant's exposure and risk assessment","volume":"771","author":"Chen","year":"2021","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.envres.2024.119159_bib9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/humupd\/dmaa053","article-title":"Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction","volume":"27","author":"Colson","year":"2021","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.envres.2024.119159_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106054","article-title":"Triphenyl phosphate exposure induces kidney structural damage and gut microbiota disorders in mice under different diets","volume":"144","author":"Cui","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119159_bib11","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.scitotenv.2016.02.171","article-title":"Organophosphate ester flame retardants and plasticizers in human placenta in Eastern China","volume":"554\u2013555","author":"Ding","year":"2016","journal-title":"Sci. Total Environ."},{"issue":"1","key":"10.1016\/j.envres.2024.119159_bib12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/hr.2016.97","article-title":"Mesenchymal-to-epithelial transition in the placental tissues of patients with preeclampsia","volume":"40","author":"Du","year":"2017","journal-title":"Hypertens. Res.: official journal of the Japanese Society of Hypertension"},{"key":"10.1016\/j.envres.2024.119159_bib13","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.semcancer.2019.05.012","article-title":"Role of the PI3K\/AKT\/mTOR signaling pathway in ovarian cancer: biological and therapeutic significance","volume":"59","author":"Ediriweera","year":"2019","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.envres.2024.119159_bib14","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1477-7827-10-15","article-title":"Down-regulation of the transcription factor snail in the placentas of patients with preeclampsia and in a rat model of preeclampsia","volume":"10","author":"Fedorova","year":"2012","journal-title":"Reprod. Biol. Endocrinol. : RB Elektron."},{"issue":"2\u20133","key":"10.1016\/j.envres.2024.119159_bib15","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.placenta.2006.04.009","article-title":"PPARs and the placenta","volume":"28","author":"Fournier","year":"2007","journal-title":"Placenta"},{"issue":"2","key":"10.1016\/j.envres.2024.119159_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jri.2007.05.004","article-title":"Role of nuclear receptors and their ligands in human trophoblast invasion","volume":"77","author":"Fournier","year":"2008","journal-title":"J. Reprod. Immunol."},{"issue":"4","key":"10.1016\/j.envres.2024.119159_bib65","doi-asserted-by":"crossref","first-page":"E357","DOI":"10.1152\/ajpendo.00093.2015","article-title":"PPAR\u03b3 controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development","volume":"309","author":"Garnier","year":"2015","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.envres.2024.119159_bib17","doi-asserted-by":"crossref","first-page":"E357","DOI":"10.1152\/ajpendo.00093.2015","article-title":"PPAR\u03b3 controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development","volume":"309","author":"Garnier","year":"2015","journal-title":"Am. J. Physiol. Endocrinol. Metabol."},{"issue":"6","key":"10.1016\/j.envres.2024.119159_bib18","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1002\/uog.18959","article-title":"Genetic and non-genetic risk factors for pre-eclampsia: umbrella review of systematic reviews and meta-analyses of observational studies","volume":"51","author":"Giannakou","year":"2018","journal-title":"Ultrasound Obstet. Gynecol.: the official journal of the International Society of Ultrasound in Obstetrics and Gynecology"},{"issue":"1","key":"10.1016\/j.envres.2024.119159_bib19","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.mce.2009.12.015","article-title":"New insights into the regulation of human cytotrophoblast cell differentiation","volume":"323","author":"Handwerger","year":"2010","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2024.119159_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.133997","article-title":"Large-scale distribution of organophosphate esters (flame retardants and plasticizers) in soil from residential area across China: implications for current level","volume":"697","author":"He","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"3","key":"10.1016\/j.envres.2024.119159_bib21","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.placenta.2009.12.009","article-title":"Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: gestational diabetes mellitus, intrauterine growth restriction and preeclampsia","volume":"31","author":"Holdsworth-Carson","year":"2010","journal-title":"Placenta"},{"key":"10.1016\/j.envres.2024.119159_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119039","article-title":"Prenatal exposure to triphenyl phosphate activated PPAR\u03b3 in placental trophoblasts and impaired pregnancy outcomes","volume":"301","author":"Hong","year":"2022","journal-title":"Environmental pollution (Barking, Essex: 1987)"},{"issue":"7","key":"10.1016\/j.envres.2024.119159_bib24","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1021\/acs.est.7b00872","article-title":"Activation of peroxisome proliferator-activated receptor gamma and disruption of progesterone synthesis of 2-ethylhexyl diphenyl phosphate in human placental choriocarcinoma cells: comparison with triphenyl phosphate","volume":"51","author":"Hu","year":"2017","journal-title":"Environ. Sci. Technol."},{"issue":"2","key":"10.1016\/j.envres.2024.119159_bib26","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1080\/13813455.2019.1687523","article-title":"DoseCal: a virtual calculator for dosage conversion between human and different animal species","volume":"128","author":"Janhavi","year":"2022","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.envres.2024.119159_bib27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.placenta.2020.10.005","article-title":"The role of \u03b2-HCG and VEGF-MEK\/ERK signaling pathway in villi angiogenesis in patients with missed abortion","volume":"103","author":"Jing","year":"2021","journal-title":"Placenta"},{"issue":"9","key":"10.1016\/j.envres.2024.119159_bib28","doi-asserted-by":"crossref","first-page":"3087","DOI":"10.1007\/s00204-020-02815-1","article-title":"Triphenyl phosphate is a selective PPAR\u03b3 modulator that does not induce brite adipogenesis in vitro and in vivo","volume":"94","author":"Kim","year":"2020","journal-title":"Arch. Toxicol."},{"issue":"3","key":"10.1016\/j.envres.2024.119159_bib29","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/nrm3758","article-title":"Molecular mechanisms of epithelial-mesenchymal transition","volume":"15","author":"Lamouille","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envres.2024.119159_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101697","article-title":"Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer","volume":"37","author":"Lee","year":"2020","journal-title":"Redox Biol."},{"issue":"18","key":"10.1016\/j.envres.2024.119159_bib31","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1021\/acs.est.2c06503","article-title":"Organophosphate flame retardants in pregnant women: sources, occurrence, and potential risks to pregnancy outcomes","volume":"57","author":"Li","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119159_bib64","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.intimp.2017.05.036","article-title":"Pioglitazone attenuates lipopolysaccharide-induced depression-like behaviors, modulates NF-\u03baB\/IL-6\/STAT3, CREB\/BDNF pathways and central serotonergic neurotransmission in mice","volume":"49","author":"Liao","year":"2017","journal-title":"Int Immunopharmacol"},{"issue":"9","key":"10.1016\/j.envres.2024.119159_bib32","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.419","article-title":"ANGPTL4 mediates the protective role of PPAR\u03b3 activators in the pathogenesis of preeclampsia","volume":"8","author":"Liu","year":"2017","journal-title":"Cell Death Dis."},{"issue":"6","key":"10.1016\/j.envres.2024.119159_bib33","doi-asserted-by":"crossref","first-page":"3375","DOI":"10.1021\/acs.est.9b06026","article-title":"Prenatal exposure to organophosphate flame retardants and the risk of low birth weight: a nested case-control study in China","volume":"54","author":"Luo","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119159_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124754","article-title":"Trimester-specific effects of maternal exposure to organophosphate flame retardants on offspring size at birth: a prospective cohort study in China","volume":"406","author":"Luo","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envres.2024.119159_bib35","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.biopha.2018.10.082","article-title":"Preeclampsia: a close look at renal dysfunction","volume":"109","author":"Moghaddas Sani","year":"2019","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"issue":"10","key":"10.1016\/j.envres.2024.119159_bib61","doi-asserted-by":"crossref","first-page":"4969","DOI":"10.1210\/en.2010-0131","article-title":"PPARgamma in placental angiogenesis","volume":"151","author":"Nadra","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.envres.2024.119159_bib36","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.placenta.2022.02.004","article-title":"Diminished trophoblast differentiation in early onset preeclampsia","volume":"120","author":"Natenzon","year":"2022","journal-title":"Placenta"},{"key":"10.1016\/j.envres.2024.119159_bib37","series-title":"Proposed Designation of Triphenyl Phosphate (CASRN 115-86-6) as a High-Priority Substance for Risk Evaluation","year":"2019"},{"key":"10.1016\/j.envres.2024.119159_bib38","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.scitotenv.2018.02.053","article-title":"Organophosphate flame retardants and plasticizers in indoor dust, air and window wipes in newly built low-energy preschools","volume":"628\u2013629","author":"Persson","year":"2018","journal-title":"Sci. Total Environ."},{"issue":"9\u201310","key":"10.1016\/j.envres.2024.119159_bib40","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.placenta.2005.12.006","article-title":"The uterine spiral arteries in human pregnancy: facts and controversies","volume":"27","author":"Pijnenborg","year":"2006","journal-title":"Placenta"},{"issue":"11","key":"10.1016\/j.envres.2024.119159_bib60","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1289\/ehp.1408111","article-title":"Ligand binding and activation of PPAR\u03b3 by Firemaster\u00ae 550: effects on adipogenesis and osteogenesis in vitro","volume":"122","author":"Pillai","year":"2014","journal-title":"Environ Health Perspect"},{"issue":"8","key":"10.1016\/j.envres.2024.119159_bib41","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1161\/CIRCRESAHA.110.226860","article-title":"The PPAR-RXR transcriptional complex in the vasculature: energy in the balance","volume":"108","author":"Plutzky","year":"2011","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.envres.2024.119159_bib42","doi-asserted-by":"crossref","DOI":"10.1289\/EHP3730","article-title":"The role of peroxisome proliferator\u2013activated receptor gamma (PPAR\u03b3) in mono(2-ethylhexyl) phthalate (MEHP)-Mediated cytotrophoblast differentiation","volume":"127","author":"Shoaito","year":"2019","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2024.119159_bib44","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/00039896.1960.10662665","article-title":"Studies on the industrial hygiene and toxicology of triphenyl phosphate","volume":"1","author":"Sutton","year":"1960","journal-title":"Archives of environmental health"},{"key":"10.1016\/j.envres.2024.119159_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.115756","article-title":"Perinatal triphenyl phosphate exposure induces metabolic dysfunctions through the EGFR\/ERK\/AKT signaling pathway: mechanistic in vitro and in vivo studies","volume":"269","author":"Tachachartvanich","year":"2024","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"1","key":"10.1016\/j.envres.2024.119159_bib46","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12940-020-00617-7","article-title":"Association of polybrominated diphenyl ether (PBDE) levels with biomarkers of placental development and disease during mid-gestation","volume":"19","author":"Varshavsky","year":"2020","journal-title":"Environ. Health: a global access science source"},{"issue":"10","key":"10.1016\/j.envres.2024.119159_bib59","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.chemosphere.2012.03.067","article-title":"Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis","volume":"88","author":"van der Veen","year":"2012","journal-title":"Chemosphere"},{"issue":"2","key":"10.1016\/j.envres.2024.119159_bib47","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/toxsci\/kfab028","article-title":"Organophosphate flame retardants, highly fluorinated chemicals, and biomarkers of placental development and disease during mid-gestation","volume":"181","author":"Varshavsky","year":"2021","journal-title":"Toxicol. Sci.: an official journal of the Society of Toxicology"},{"issue":"5","key":"10.1016\/j.envres.2024.119159_bib48","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/ajh.2008.20","article-title":"Secular trends in the rates of preeclampsia, eclampsia, and gestational hypertension, United States, 1987-2004","volume":"21","author":"Wallis","year":"2008","journal-title":"Am. J. Hypertens."},{"issue":"8\u20139","key":"10.1016\/j.envres.2024.119159_bib49","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1053\/plac.2002.0855","article-title":"Expression of PPAR and RXR isoforms in the developing rat and human term placentas","volume":"23","author":"Wang","year":"2002","journal-title":"Placenta"},{"key":"10.1016\/j.envres.2024.119159_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.109493","article-title":"Estimation of internal human daily intakes of organophosphate esters using one-compartment toxicokinetic model in the whole blood from Hebei Province, China","volume":"186","author":"Wang","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2024.119159_bib51","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ceb.2020.08.010","article-title":"Progress in deciphering trophoblast cell differentiation during human placentation","volume":"67","author":"Xiao","year":"2020","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.envres.2024.119159_bib52","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.biopha.2018.02.134","article-title":"Overexpression of long non-coding RNA H19 promotes invasion and autophagy via the PI3K\/AKT\/mTOR pathways in trophoblast cells","volume":"101","author":"Xu","year":"2018","journal-title":"Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie"},{"issue":"5","key":"10.1016\/j.envres.2024.119159_bib53","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10273","article-title":"Screening of organophosphate flame retardants with placentation-disrupting effects in human trophoblast organoid model and characterization of adverse pregnancy outcomes in mice","volume":"130","author":"Xu","year":"2022","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.envres.2024.119159_bib55","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1096\/fj.201800934RRR","article-title":"Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2","volume":"33","author":"Ye","year":"2019","journal-title":"Faseb. J. : official publication of the Federation of American Societies for Experimental Biology"},{"key":"10.1016\/j.envres.2024.119159_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2019.113593","article-title":"Exposure to DEHP or its metabolite MEHP promotes progesterone secretion and inhibits proliferation in mouse placenta or JEG-3 cells","volume":"257","author":"Zhang","year":"2020","journal-title":"Environ. Pollut."},{"issue":"11","key":"10.1016\/j.envres.2024.119159_bib57","doi-asserted-by":"crossref","first-page":"6489","DOI":"10.1021\/acs.est.7b01122","article-title":"Organophosphorus flame retardants in pregnant women and their transfer to chorionic villi","volume":"51","author":"Zhao","year":"2017","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.envres.2024.119159_bib58","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s13045-019-0840-4","article-title":"Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K\/AKT\/GSK3\u03b2 signalling pathway in renal cell carcinoma","volume":"13","author":"Zhu","year":"2020","journal-title":"J. Hematol. Oncol."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124010648?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124010648?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T03:30:09Z","timestamp":1762140609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935124010648"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":58,"alternative-id":["S0013935124010648"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2024.119159","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal triphenyl phosphate exposure impairs placentation and induces preeclampsia-like symptoms in mice","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2024.119159","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"119159"}}