{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:04:54Z","timestamp":1789661094552,"version":"4.0.1"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100016691","name":"Guangdong Provincial Pearl River Talents Program","doi-asserted-by":"publisher","award":["0920220207"],"award-info":[{"award-number":["0920220207"]}],"id":[{"id":"10.13039\/100016691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020084","name":"Guangzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["2023A04J2072"],"award-info":[{"award-number":["2023A04J2072"]}],"id":[{"id":"10.13039\/501100020084","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010097","name":"China Association for Science and Technology","doi-asserted-by":"publisher","award":["2023QNRC001"],"award-info":[{"award-number":["2023QNRC001"]}],"id":[{"id":"10.13039\/100010097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515010823"],"award-info":[{"award-number":["2022A1515010823"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3600804"],"award-info":[{"award-number":["2022YFC3600804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82204162"],"award-info":[{"award-number":["82204162"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012692","name":"K. C. Wong Education Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012692","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002402","name":"Sun Yat-sen University","doi-asserted-by":"publisher","award":["23qnpy108"],"award-info":[{"award-number":["23qnpy108"]}],"id":[{"id":"10.13039\/501100002402","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.envres.2024.119644","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T23:38:48Z","timestamp":1721864328000},"page":"119644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The joint impact of PM2.5 constituents on the risk of cerebrovascular diseases hospitalization: A large community-based cohort study"],"prefix":"10.1016","volume":"260","author":[{"given":"Shirui","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqiang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruqing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuyuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanji","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wangjian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4146-9262","authenticated-orcid":false,"given":"Yuantao","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2024.119644_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2017.09.010","article-title":"Acute effects of fine particulate matter constituents on mortality: a systematic review and meta-regression analysis","volume":"109","author":"Achilleos","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s13253-014-0180-3","article-title":"Characterization of weighted quantile sum regression for highly correlated data in a risk analysis setting","volume":"20","author":"Carrico","year":"2015","journal-title":"J. Agric. Biol. Environ. Stat."},{"key":"10.1016\/j.envres.2024.119644_bib3","article-title":"Environmental justice assessment of fine particles, ozone, and mercury over the pearl river delta region, China","volume":"14","author":"Chang","year":"2022","journal-title":"Sustainability"},{"key":"10.1016\/j.envres.2024.119644_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.130740","article-title":"The prospective effects of long-term exposure to ambient pm2.5 and constituents on mortality in rural east China","volume":"280","author":"Chen","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2024.119644_bib5","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1126\/science.1092805","article-title":"Formation of secondary organic aerosols through photooxidation of isoprene","volume":"303","author":"Claeys","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.envres.2024.119644_bib6","first-page":"5","article-title":"Part 1. Statistical learning methods for the effects of multiple air pollution constituents","author":"Coull","year":"2015","journal-title":"Res. Rep. Health Eff. Inst."},{"key":"10.1016\/j.envres.2024.119644_bib7","doi-asserted-by":"crossref","DOI":"10.1289\/EHP3047","article-title":"Long-term exposure to ultrafine particles and incidence of cardiovascular and cerebrovascular disease in a prospective study of a Dutch cohort","volume":"126","author":"Downward","year":"2018","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2024.119644_bib8","doi-asserted-by":"crossref","first-page":"6835","DOI":"10.1021\/acs.est.2c07064","article-title":"National cohort study of long-term exposure to pm(2.5) components and mortality in medicare american older adults","volume":"57","author":"Hao","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119644_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanwpc.2023.100776","article-title":"Individual and joint associations of long-term exposure to air pollutants and cardiopulmonary mortality: a 22-year cohort study in northern China","volume":"36","author":"Huang","year":"2023","journal-title":"The Lancet Regional Health - Western Pacific"},{"key":"10.1016\/j.envres.2024.119644_bib10","doi-asserted-by":"crossref","first-page":"e235","DOI":"10.1016\/S2542-5196(20)30103-0","article-title":"Associations of outdoor fine particulate air pollution and cardiovascular disease in 157 436 individuals from 21 high-income, middle-income, and low-income countries (pure): a prospective cohort study","volume":"4","author":"Hystad","year":"2020","journal-title":"Lancet Planet. Health"},{"key":"10.1016\/j.envres.2024.119644_bib11","series-title":"Gbd Compare","year":"2023"},{"key":"10.1016\/j.envres.2024.119644_bib12","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/eurheartj\/ehad091","article-title":"Ozone pollution and hospital admissions for cardiovascular events","volume":"44","author":"Jiang","year":"2023","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.envres.2024.119644_bib13","doi-asserted-by":"crossref","DOI":"10.1289\/EHP5838","article-title":"A quantile-based g-computation approach to addressing the effects of exposure mixtures","volume":"128","author":"Keil","year":"2020","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2024.119644_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106798","article-title":"Prenatal and postnatal exposures to four metals mixture and iq in 6-year-old children: a prospective cohort study in South Korea","volume":"157","author":"Lee","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib15","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.jacc.2019.12.031","article-title":"Long-term exposure to fine particulate matter and cardiovascular disease in China","volume":"75","author":"Liang","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.envres.2024.119644_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107156","article-title":"Associations of long-term exposure to fine particulate matter and its constituents with cardiovascular mortality: a prospective cohort study in China","volume":"162","author":"Liang","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.envint.2016.09.007","article-title":"Mortality burden of ambient fine particulate air pollution in six Chinese cities: results from the pearl river delta study","volume":"96","author":"Lin","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.126051","article-title":"Long-term exposure to fine particulate constituents and cardiovascular diseases in Chinese adults","volume":"416","author":"Liu","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envres.2024.119644_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118990","article-title":"Green space and cardiovascular disease: a systematic review with meta-analysis","volume":"301","author":"Liu","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.119644_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.142489","article-title":"Effects of exposure to chemical components of fine particulate matter on mortality in tokyo: A case-crossover study","volume":"755","author":"Michikawa","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.119644_bib21","doi-asserted-by":"crossref","first-page":"7214","DOI":"10.1021\/acs.est.1c04176","article-title":"Cardiopulmonary mortality and fine particulate air pollution by species and source in a national u.S. Cohort","volume":"56","author":"Pond","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119644_bib22","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1186\/s12879-019-4150-9","article-title":"Establishment and development of national community-based collaborative innovation demonstration areas to achieve the control target of hepatitis b in China","volume":"19","author":"Ruan","year":"2019","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.envres.2024.119644_bib23","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00477-020-01786-0","article-title":"The effect of ambient fine particulate matter (pm2.5) on respiratory diseases in China: a systematic review and meta-analysis","volume":"34","author":"Sun","year":"2020","journal-title":"Stoch. Environ. Res. Risk Assess."},{"key":"10.1016\/j.envres.2024.119644_bib24","first-page":"33","article-title":"China stroke surveillance report 2021","volume":"10","author":"Tu","year":"2023","journal-title":"Mil Med Res"},{"key":"10.1016\/j.envres.2024.119644_bib25","doi-asserted-by":"crossref","first-page":"268","DOI":"10.7326\/M16-2607","article-title":"Sensitivity analysis in observational research: introducing the e-value","volume":"167","author":"VanderWeele","year":"2017","journal-title":"Annals of internal medicine"},{"key":"10.1016\/j.envres.2024.119644_bib26","doi-asserted-by":"crossref","first-page":"13025","DOI":"10.1021\/acs.est.3c03928","article-title":"Exposure to fine particulate matter constituents and human semen quality decline: a multicenter study","volume":"57","author":"Wang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119644_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2014.01.026","article-title":"Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 european cohorts: results from the escape and transphorm projects","volume":"66","author":"Wang","year":"2014","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib28","doi-asserted-by":"crossref","first-page":"7863","DOI":"10.5194\/acp-21-7863-2021","article-title":"Himawari-8-derived diurnal variations in ground-level pm2.5 pollution across China using the fast space-time light gradient boosting machine (lightgbm)","volume":"21","author":"Wei","year":"2021","journal-title":"Atmos. Chem. Phys."},{"key":"10.1016\/j.envres.2024.119644_bib29","doi-asserted-by":"crossref","first-page":"18282","DOI":"10.1021\/acs.est.3c00272","article-title":"Separating daily 1 km PM2.5 inorganic chemical composition in China since 2000 via deep learning integrating ground, satellite, and model data","volume":"57","author":"Wei","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119644_bib30","doi-asserted-by":"crossref","first-page":"8349","DOI":"10.1038\/s41467-023-43862-3","article-title":"First close insight into global daily gapless 1 km pm2.5 pollution, variability, and health impact","volume":"14","author":"Wei","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.envres.2024.119644_bib31","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.5194\/acp-23-1511-2023","article-title":"Ground-level gaseous pollutants (no2, so2, and co) in China: daily seamless mapping and spatiotemporal variations","volume":"23","author":"Wei","year":"2023","journal-title":"Atmos. Chem. Phys."},{"key":"10.1016\/j.envres.2024.119644_bib32","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10389","article-title":"The impact of exposure measurement error on the estimated concentration-response relationship between long-term exposure to pm2.5 and mortality","volume":"130","author":"Wei","year":"2022","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2024.119644_bib33","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1743-8977-9-49","article-title":"Chemical constituents of ambient particulate air pollution and biomarkers of inflammation, coagulation and homocysteine in healthy adults: a prospective panel study","volume":"9","author":"Wu","year":"2012","journal-title":"Part. Fibre Toxicol."},{"key":"10.1016\/j.envres.2024.119644_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106707","article-title":"Association of fine particulate matter air pollution and its constituents with lung function: the China pulmonary health study","volume":"156","author":"Yang","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105589","article-title":"Associations of long-term exposure to ambient pm2.5 with mortality in Chinese adults: a pooled analysis of cohorts in the China-par project","volume":"138","author":"Yang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2024.119644_bib36","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1021\/acs.est.1c05634","article-title":"Global emissions of hydrogen chloride and particulate chloride from continental sources","volume":"56","author":"Zhang","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2024.119644_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.135989","article-title":"The acute effects of fine particulate matter constituents on circulating inflammatory biomarkers in healthy adults","volume":"707","author":"Zhang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2024.119644_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114149","article-title":"Associations between short-term exposure of pm(2.5) constituents and hospital admissions of cardiovascular diseases among 18 major Chinese cities","volume":"246","author":"Zhang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124015494?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124015494?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:16:41Z","timestamp":1789658201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935124015494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":38,"alternative-id":["S0013935124015494"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2024.119644","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The joint impact of PM2.5 constituents on the risk of cerebrovascular diseases hospitalization: A large community-based cohort study","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2024.119644","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"119644"}}