{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T18:17:53Z","timestamp":1747160273344,"version":"3.40.5"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.envres.2024.120063","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T06:21:49Z","timestamp":1727331709000},"page":"120063","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"P2","title":["Parathyroid hormone mediates the adverse impact of air pollution exposure on serum 25-hydroxyvitamin D: A nationwide cross-sectional study in China"],"prefix":"10.1016","volume":"263","author":[{"given":"Haitao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunchun","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingwen","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhangyu","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaobing","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bolai","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinchao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyang","family":"Leng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1871-8999","authenticated-orcid":false,"given":"Haidong","family":"Kan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dezhi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongjun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.envres.2024.120063_bib1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1136\/adc.87.2.111","article-title":"The impact of atmospheric pollution on vitamin D status of infants and toddlers in Delhi, India","volume":"87","author":"Agarwal","year":"2002","journal-title":"Arch. Dis. Child."},{"issue":"2","key":"10.1016\/j.envres.2024.120063_bib2","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.bone.2010.05.002","article-title":"Age but not gender modulates the relationship between PTH and vitamin D","volume":"47","author":"Arabi","year":"2010","journal-title":"Bone"},{"issue":"9","key":"10.1016\/j.envres.2024.120063_bib3","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.amjmed.2003.12.029","article-title":"Positive association between 25-hydroxy vitamin D levels and bone mineral density: a population-based study of younger and older adults","volume":"116","author":"Bischoff-Ferrari","year":"2004","journal-title":"Am. J. Med."},{"issue":"4","key":"10.1016\/j.envres.2024.120063_bib4","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1210\/er.2018-00126","article-title":"Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions","volume":"40","author":"Bouillon","year":"2019","journal-title":"Endocr. Rev."},{"issue":"2","key":"10.1016\/j.envres.2024.120063_bib5","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00394-020-02298-x","article-title":"Individual participant data (IPD)-level meta-analysis of randomised controlled trials with vitamin D-fortified foods to estimate Dietary Reference Values for vitamin D","volume":"60","author":"Cashman","year":"2021","journal-title":"Eur. J. Nutr."},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00223-010-9360-5","article-title":"Parathyroid hormone and bone healing","volume":"87","author":"Ellegaard","year":"2010","journal-title":"Calcif. Tissue Int."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.atmosres.2006.08.004","article-title":"Sensitivity of ultraviolet solar radiation to anthropogenic air pollutants and weather conditions","volume":"84","author":"Elminir","year":"2007","journal-title":"Atmos. Res."},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib8","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/s11657-017-0323-6","article-title":"Impact of air pollution on vitamin D deficiency and bone health in adolescents","volume":"12","author":"Feizabad","year":"2017","journal-title":"Arch. Osteoporosis"},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.nutres.2010.12.001","article-title":"Prevalence and correlates of vitamin D deficiency in US adults","volume":"31","author":"Forrest","year":"2011","journal-title":"Nutr. Res. (N.Y.)"},{"issue":"10258","key":"10.1016\/j.envres.2024.120063_bib10","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/S0140-6736(20)30752-2","article-title":"Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019","volume":"396","year":"2020","journal-title":"Lancet (London, England)"},{"issue":"6","key":"10.1016\/j.envres.2024.120063_bib11","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1007\/s00198-010-1383-2","article-title":"Racial differences in the relationship between vitamin D, bone mineral density, and parathyroid hormone in the National Health and Nutrition Examination Survey","volume":"22","author":"Guti\u00e9rrez","year":"2011","journal-title":"Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA"},{"key":"10.1016\/j.envres.2024.120063_bib12","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.2147\/RMHP.S273145","article-title":"Meteorological condition and air pollution exposure associated with vitamin D deficiency: a cross-sectional population-based study in China","volume":"13","author":"He","year":"2020","journal-title":"Risk Manag. Healthc. Pol."},{"issue":"7","key":"10.1016\/j.envres.2024.120063_bib13","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00264-019-04334-w","article-title":"Vitamin D history part III: the \"modern times\"-new questions for orthopaedic practice: deficiency, cell therapy, osteomalacia, fractures, supplementation, infections","volume":"43","author":"Hernigou","year":"2019","journal-title":"Int. Orthop."},{"issue":"8","key":"10.1016\/j.envres.2024.120063_bib14","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1172\/JCI29449","article-title":"Resurrection of vitamin D deficiency and rickets","volume":"116","author":"Holick","year":"2006","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib15","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.envres.2024.120063_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1232285","article-title":"Six years' experience and trends of serum 25-hydroxy vitamin D concentration and the effect of vitamin D(3) consumption on these trends","volume":"14","author":"Horv\u00e1th","year":"2023","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.envres.2024.120063_bib17","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.fct.2018.01.052","article-title":"The impact of air pollutants, UV exposure and geographic location on vitamin D deficiency","volume":"113","author":"Hoseinzadeh","year":"2018","journal-title":"Food Chem. Toxicol. : an international journal published for the British Industrial Biological Research Association"},{"key":"10.1016\/j.envres.2024.120063_bib18","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1186\/1471-2458-10-519","article-title":"The effects of air pollution on vitamin D status in healthy women: a cross sectional study","volume":"10","author":"Hosseinpanah","year":"2010","journal-title":"BMC Publ. Health"},{"issue":"16","key":"10.1016\/j.envres.2024.120063_bib19","first-page":"15","article-title":"The role of vitamin D in cardiovascular diseases","author":"Hung","year":"2023","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib20","doi-asserted-by":"crossref","DOI":"10.1080\/22423982.2016.1272790","article-title":"The effect of vernal solar UV radiation on serum 25-hydroxyvitamin D concentration depends on the baseline level: observations from a high latitude in Finland","volume":"76","author":"Karppinen","year":"2017","journal-title":"Int. J. Circumpolar Health"},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib21","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1179\/2046905513Y.0000000080","article-title":"Independent association between air pollutants and vitamin D deficiency in young children in Isfahan, Iran","volume":"34","author":"Kelishadi","year":"2014","journal-title":"Paediatr. Int. Child Health"},{"issue":"4","key":"10.1016\/j.envres.2024.120063_bib22","doi-asserted-by":"crossref","DOI":"10.5620\/eaht.2020023","article-title":"Effects of sulfur dioxide, ozone, and ambient air pollution on bone metabolism related biochemical parameters in a rat model","volume":"35","author":"Kheirouri","year":"2020","journal-title":"Environmental analysis, health and toxicology"},{"issue":"4","key":"10.1016\/j.envres.2024.120063_bib23","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1210\/endo.141.4.7403","article-title":"Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads","volume":"141","author":"Kinuta","year":"2000","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.envres.2024.120063_bib24","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.ijheh.2019.05.005","article-title":"Ambient particulate air pollution and circulating C-reactive protein level: a systematic review and meta-analysis","volume":"222","author":"Liu","year":"2019","journal-title":"Int. J. Hyg Environ. Health"},{"issue":"8","key":"10.1016\/j.envres.2024.120063_bib25","first-page":"14","article-title":"Influence of obesity on bone turnover markers and fracture risk in postmenopausal women","author":"L\u00f3pez-G\u00f3mez","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.envres.2024.120063_bib26","article-title":"Estimating PM(2.5) concentrations in Northeastern China with full spatiotemporal coverage, 2005-2016","volume":"253doi","author":"Meng","year":"2021","journal-title":"Remote Sens. Environ."},{"key":"10.1016\/j.envres.2024.120063_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.118865","article-title":"Evaluating the spatiotemporal ozone characteristics with high-resolution predictions in mainland China, 2013-2019","volume":"299","author":"Meng","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2024.120063_bib28","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.envint.2018.11.052","article-title":"Air pollution, environmental chemicals, and smoking may trigger vitamin D deficiency: evidence and potential mechanisms","volume":"122","author":"Mousavi","year":"2019","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib29","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.drudis.2013.07.015","article-title":"Treating osteoporosis by targeting parathyroid hormone to bone","volume":"19","author":"Ponnapakkam","year":"2014","journal-title":"Drug Discov. Today"},{"issue":"2","key":"10.1016\/j.envres.2024.120063_bib30","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/2047-783X-15-S2-120","article-title":"Proinflammatory cytokines IL-6 and TNF-\u03b1 and the development of inflammation in obese subjects","volume":"15","author":"Popko","year":"2010","journal-title":"Eur. J. Med. Res."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib31","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s11914-020-00574-7","article-title":"Effects of PTH and PTH hypersecretion on bone: a clinical perspective","volume":"18","author":"Rejnmark","year":"2020","journal-title":"Curr. Osteoporos. Rep."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib32","doi-asserted-by":"crossref","first-page":"E436","DOI":"10.1210\/jc.2010-1886","article-title":"Relationship between vitamin D, parathyroid hormone, and bone health","volume":"96","author":"Sai","year":"2011","journal-title":"J. Clin. Endocrinol. Metabol."},{"issue":"6","key":"10.1016\/j.envres.2024.120063_bib33","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1530\/EJE-22-0530","article-title":"Fat, adipokines, bone structure and bone regulatory factors associations in obesity","volume":"187","author":"Vilaca","year":"2022","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.envres.2024.120063_bib34","article-title":"The prevalence of osteoporosis in China, a community based cohort study of osteoporosis","volume":"11","author":"Wang","year":"2023","journal-title":"Front. Public Health"},{"issue":"4","key":"10.1016\/j.envres.2024.120063_bib35","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.bone.2005.10.009","article-title":"Parathyroid hormone activates PKC-delta and regulates osteoblastic differentiation via a PLC-independent pathway","volume":"38","author":"Yang","year":"2006","journal-title":"Bone"},{"issue":"1","key":"10.1016\/j.envres.2024.120063_bib36","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12940-019-0476-4","article-title":"Particulate air pollution on cardiovascular mortality in the tropics: impact on the elderly","volume":"18","author":"Yap","year":"2019","journal-title":"Environ. Health : a global access science source"},{"key":"10.1016\/j.envres.2024.120063_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1162175","article-title":"Effects of obesity with reduced 25(OH)D levels on bone health in elderly Chinese people: a nationwide cross-sectional study","volume":"14","author":"Yuan","year":"2023","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.envres.2024.120063_bib38","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1210\/jc.2018-02713","article-title":"Particulate air pollution exposure and plasma vitamin D levels in pregnant women: a longitudinal cohort study","volume":"104","author":"Zhao","year":"2019","journal-title":"J. Clin. Endocrinol. Metabol."},{"issue":"3","key":"10.1016\/j.envres.2024.120063_bib39","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.tjnut.2023.01.006","article-title":"Associations between serum 25-hydroxyvitamin D, sun exposure time, dietary vitamin D intake, and new-onset acute kidney injury among 413,169 UK adults","volume":"153","author":"Zhou","year":"2023","journal-title":"J. Nutr."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124019704?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935124019704?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T03:58:10Z","timestamp":1732852690000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935124019704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":39,"alternative-id":["S0013935124019704"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2024.120063","relation":{},"ISSN":["0013-9351"],"issn-type":[{"type":"print","value":"0013-9351"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Parathyroid hormone mediates the adverse impact of air pollution exposure on serum 25-hydroxyvitamin D: A nationwide cross-sectional study in China","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2024.120063","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"120063"}}