{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T20:08:56Z","timestamp":1788206936795,"version":"build-2803163510"},"reference-count":106,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020484","name":"Directed Energy Professional Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020484","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"French National Research Agency","doi-asserted-by":"publisher","award":["ANR-19-COHO-0001"],"award-info":[{"award-number":["ANR-19-COHO-0001"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"French National Research Agency","doi-asserted-by":"publisher","award":["ANR-11-EQPX-0038"],"award-info":[{"award-number":["ANR-11-EQPX-0038"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002915","name":"Foundation for Medical Research","doi-asserted-by":"publisher","award":["ENV202109013943"],"award-info":[{"award-number":["ENV202109013943"]}],"id":[{"id":"10.13039\/501100002915","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005348","name":"Socialdepartementet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001525","name":"Ministry For The Environment","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001525","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011044","name":"Minist\u00e8re de la Culture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011044","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004562","name":"Minist\u00e8re de l'Enseignement sup\u00e9rieur et de la Recherche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.envres.2025.121062","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T02:37:01Z","timestamp":1738809421000},"page":"121062","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Prenatal exposure to heavy metals and childhood atopic disease"],"prefix":"10.1016","volume":"270","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9925-8460","authenticated-orcid":false,"given":"Courtney","family":"Dow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manik","family":"Kadawathagedara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2319-6303","authenticated-orcid":false,"given":"Manel","family":"Ghozal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Aline","family":"Charles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2242-0626","authenticated-orcid":false,"given":"Karine","family":"Adel-Patient","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9mentine","family":"Dereumeaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5887-8842","authenticated-orcid":false,"given":"Blandine","family":"de Lauzon-Guillain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2025.121062_bib1","series-title":"Toxicological Profile for Cesium. Atlanta, GA","year":"2004"},{"key":"10.1016\/j.envres.2025.121062_bib2","series-title":"Toxicological Profile for Tin and Tin Compounds. Atlanta, GA","year":"2005"},{"key":"10.1016\/j.envres.2025.121062_bib3","series-title":"Toxicological Profile for Arsenic. Atlanta, GA","year":"2007"},{"key":"10.1016\/j.envres.2025.121062_bib4","series-title":"Toxicological Profile for Chromium. Atlanta, GA","year":"2012"},{"key":"10.1016\/j.envres.2025.121062_bib5","series-title":"Toxicological Profile for Vanadium. Atlanta, GA","year":"2012"},{"key":"10.1016\/j.envres.2025.121062_bib6","series-title":"Toxicological Profile for Antimony and Compounds. Atlanta, GA","year":"2019"},{"key":"10.1016\/j.envres.2025.121062_bib7","series-title":"Toxicological Profile for Mercury","year":"2022"},{"key":"10.1016\/j.envres.2025.121062_bib8","series-title":"Toxicological Profile for Nickel. Atlanta, GA","year":"2023"},{"key":"10.1016\/j.envres.2025.121062_bib9","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2105\/AJPH.92.2.284","article-title":"Cadmium exposure in pregnancy and lactation in relation to iron status","volume":"92","author":"\u00c5kesson","year":"2002","journal-title":"Am. J. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib10","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1080\/00039896.1988.10545953","article-title":"Blood and urinary concentrations as estimators of cobalt exposure","volume":"43","author":"Alexandersson","year":"1988","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib11","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/s41370-021-00289-6","article-title":"Cadmium exposure and risk of adverse pregnancy and birth outcomes: a systematic review and dose\u2013response meta-analysis of cohort and cohort-based case\u2013control studies","volume":"31","author":"Amegah","year":"2021","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib12","volume":"TDS 2","year":"2011"},{"key":"10.1016\/j.envres.2025.121062_bib13","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02094-2020","article-title":"Trends in worldwide asthma prevalence","volume":"56","author":"Asher","year":"2020","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.envres.2025.121062_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0149858","article-title":"Pregnancy requires major changes in the quality of the diet for nutritional adequacy: simulations in the French and the United States populations","volume":"11","author":"Bianchi","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2025.121062_bib15","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1080\/15592294.2015.1046026","article-title":"Differential DNA methylation in umbilical cord blood of infants exposed to mercury and arsenic in utero","volume":"10","author":"Cardenas","year":"2015","journal-title":"Epigenetics"},{"key":"10.1016\/j.envres.2025.121062_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146654","article-title":"Pre and postnatal exposure to mercury and respiratory health in preschool children from the Spanish INMA Birth Cohort Study","volume":"782","author":"Carrasco","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.121062_bib17","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/ije\/dyz227","article-title":"Cohort Profile: the French national cohort of children (ELFE): birth to 5 years","volume":"49","author":"Charles","year":"2021","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib18","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/aje\/kwy216","article-title":"Associations of prenatal exposure to cadmium with child growth, obesity, and cardiometabolic traits","volume":"188","author":"Chatzi","year":"2019","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib19","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/jes.2014.26","article-title":"Placental transfer and concentrations of cadmium, mercury, lead, and selenium in mothers, newborns, and young children","volume":"24","author":"Chen","year":"2014","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib20","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1164\/rccm.201608-1691OC","article-title":"Effects of childhood asthma on the development of obesity among school-aged children","volume":"195","author":"Chen","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envres.2025.121062_bib21","article-title":"Anthropogenic chromium emissions in China from 1990 to 2009","volume":"9","author":"Cheng","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.envres.2025.121062_bib22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40413-018-0198-z","article-title":"Epidemiology of allergic rhinitis and associated risk factors in Asia","volume":"11","author":"Chong","year":"2018","journal-title":"World Allergy Organization Journal"},{"key":"10.1016\/j.envres.2025.121062_bib23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/0019-5278.50716","article-title":"The exposure to and health effects of antimony","volume":"13","author":"Cooper","year":"2009","journal-title":"Indian J. Occup. Environ. Med."},{"key":"10.1016\/j.envres.2025.121062_bib24","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1192\/bjp.150.6.782","article-title":"Detection of postnatal depression","volume":"150","author":"Cox","year":"1987","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.envres.2025.121062_bib25","doi-asserted-by":"crossref","first-page":"1976","DOI":"10.3390\/ijerph19041976","article-title":"Prenatal mercury exposure and neurodevelopment up to the age of 5 Years: a systematic review","volume":"19","author":"Dack","year":"2022","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib26","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0091-6749(98)70080-6","article-title":"The role of IL-13 and its receptor in allergy and inflammatory responses","volume":"102","author":"de Vries","year":"1998","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envres.2025.121062_bib27","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3390\/nu15010146","article-title":"Maternal diet quality during pregnancy and allergic and respiratory multimorbidity clusters in children from the EDEN mother\u2013child cohort","volume":"15","author":"Delvert","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.envres.2025.121062_bib28","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.envint.2016.10.013","article-title":"Biomarkers of exposure to environmental contaminants in French pregnant women from the Elfe cohort in 2011","volume":"97","author":"Dereumeaux","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib29","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/14737167.2020.1819793","article-title":"Burden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy","volume":"20","author":"Dierick","year":"2020","journal-title":"Expert Rev. Pharmacoecon. Outcomes Res."},{"key":"10.1016\/j.envres.2025.121062_bib30","doi-asserted-by":"crossref","first-page":"253","DOI":"10.5409\/wjcp.v11.i3.253","article-title":"Food allergy in children\u2014the current status and the way forward","volume":"11","author":"Elghoudi","year":"2022","journal-title":"World J. Clin. Pediatr."},{"key":"10.1016\/j.envres.2025.121062_bib31","first-page":"523","article-title":"Prenatal exposure to mercury in relation to infant infections and respiratory symptoms in the New Hampshire Birth Cohort Study","author":"Emeny","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib32","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.taap.2013.06.030","article-title":"In utero and early life arsenic exposure in relation to long-term health and disease","volume":"272","author":"Farzan","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envres.2025.121062_bib33","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1289\/ehp.1409282","article-title":"Infant infections and respiratory symptoms in relation to in utero arsenic exposure in a U.S. Cohort","volume":"124","author":"Farzan","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.121062_bib34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jhealeco.2010.03.007","article-title":"Long term effects of childhood asthma on adult health","volume":"29","author":"Fletcher","year":"2010","journal-title":"J. Health Econ."},{"key":"10.1016\/j.envres.2025.121062_bib35","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.envres.2014.10.013","article-title":"Interdependence between urinary cobalt concentrations and hemoglobin levels in pregnant women","volume":"136","author":"Fort","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib36","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1080\/10934529.2019.1605779","article-title":"Levels of tin and organotin compounds in human urine samples from Iowa, United States","volume":"54","author":"Gadogbe","year":"2019","journal-title":"J. Environ. Sci. Health, Part A"},{"key":"10.1016\/j.envres.2025.121062_bib37","series-title":"Workshop in the Frame of GEMS\/Food-EURO","article-title":"Addendum 2013-second workshop on reliable evaluation of low-level contamination of food","year":"2013"},{"key":"10.1016\/j.envres.2025.121062_bib38","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.jclinepi.2014.03.012","article-title":"False discovery rate control is a recommended alternative to Bonferroni-type adjustments in health studies","volume":"67","author":"Glickman","year":"2014","journal-title":"J. Clin. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib39","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1289\/ehp.1002289","article-title":"Allergy and sensitization during childhood associated with prenatal and lactational exposure to marine pollutants","volume":"118","author":"Grandjean","year":"2010","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.121062_bib40","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/00001648-199901000-00008","article-title":"Causal diagrams for epidemiologic research","volume":"10","author":"Greenland","year":"1999","journal-title":"Epidemiology"},{"key":"10.1016\/j.envres.2025.121062_bib41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3917\/dev.013.0051","article-title":"D\u00e9pressions postnatales (DPN) et d\u00e9cisions d\u2019orientation th\u00e9rapeutique","volume":"13","author":"Gu\u00e9deney","year":"2001","journal-title":"Devenir"},{"key":"10.1016\/j.envres.2025.121062_bib42","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0048-9697(02)00355-8","article-title":"Mobilization of lead from human bone tissue during pregnancy and lactation\u2014a summary of long-term research","volume":"303","author":"Gulson","year":"2003","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.121062_bib43","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10354-012-0074-3","article-title":"The role of the placenta in fetal exposure to heavy metals","volume":"162","author":"Gundacker","year":"2012","journal-title":"Wien. Med. Wochenschr."},{"key":"10.1016\/j.envres.2025.121062_bib44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5114\/ada.2022.119009","article-title":"The increase in allergic conditions based on a review of literature","volume":"40","author":"Gutowska-\u015alesik","year":"2023","journal-title":"Adv. Dermatol. Allergol."},{"issue":"66","key":"10.1016\/j.envres.2025.121062_bib45","first-page":"1017","article-title":"The role of prenatal, perinatal and postnatal factors in the explanation of socioeconomic inequalities in preschool asthma symptoms: the Generation R Study","volume":"2012","author":"Hafkamp-de Groen","year":"1978","journal-title":"J. Epidemiol. Community Health"},{"key":"10.1016\/j.envres.2025.121062_bib46","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1111\/jdv.18425","article-title":"Prenatal exposure to nickel and atopic dermatitis at age 3 years: a birth cohort study with cytokine profiles","volume":"36","author":"Ho","year":"2022","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"10.1016\/j.envres.2025.121062_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107102","article-title":"Prenatal metal(loid) mixtures and birth weight for gestational age: a pooled analysis of three cohorts participating in the ECHO program","volume":"161","author":"Howe","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107102","article-title":"Prenatal metal(loid) mixtures and birth weight for gestational age: a pooled analysis of three cohorts participating in the ECHO program","volume":"161","author":"Howe","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib49","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.envres.2015.11.005","article-title":"Impact of fetal and childhood mercury exposure on immune status in children","volume":"144","author":"Hui","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib50","series-title":"Global Report on Atopic Dermatitis 2022. London, UK","year":"2022"},{"key":"10.1016\/j.envres.2025.121062_bib51","series-title":"Concise International Chemical Assessment Document 69. Geneva: World Health Organization","article-title":"Cobalt and inorganic cobalt compounds","author":"Kim","year":"2006"},{"key":"10.1016\/j.envres.2025.121062_bib52","doi-asserted-by":"crossref","first-page":"516","DOI":"10.3346\/jkms.2013.28.4.516","article-title":"Association between prenatal exposure to cadmium and atopic dermatitis in infancy","volume":"28","author":"Kim","year":"2013","journal-title":"J. Kor. Med. Sci."},{"key":"10.1016\/j.envres.2025.121062_bib53","doi-asserted-by":"crossref","first-page":"232","DOI":"10.15430\/JCP.2015.20.4.232","article-title":"An overview of carcinogenic heavy metal: molecular toxicity mechanism and prevention","volume":"20","author":"Kim","year":"2015","journal-title":"J Cancer Prev"},{"key":"10.1016\/j.envres.2025.121062_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4110\/in.2019.19.e42","article-title":"Prenatal exposure to lead and chromium is associated with IL-13 levels in umbilical cord blood and severity of atopic dermatitis: cocoa study","volume":"19","author":"Kim","year":"2019","journal-title":"Immune Netw"},{"key":"10.1016\/j.envres.2025.121062_bib55","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3961\/jpmph.19.175","article-title":"The effect of prenatal cadmium exposure on attention-deficit\/hyperactivity disorder in 6-Year-old children in Korea","volume":"53","author":"Kim","year":"2020","journal-title":"J. Prev. Med.Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib56","doi-asserted-by":"crossref","first-page":"540","DOI":"10.2105\/AJPH.2008.150771","article-title":"Association between socioeconomic status and the development of asthma: analyses of income trajectories","volume":"100","author":"Kozyrskyj","year":"2010","journal-title":"Am. J. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib57","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1080\/15287390903213061","article-title":"Dietary exposure and risk assessment of mercury from the Korean total diet study","volume":"72","author":"Kwon","year":"2009","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.envres.2025.121062_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.110865","article-title":"Prenatal heavy metal exposures and atopic dermatitis with gender difference in 6-month-old infants using multipollutant analysis","volume":"195","author":"Lee","year":"2021","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib59","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2023.1133312","article-title":"The relationship between childhood asthma and socioeconomic status: a Korean nationwide population-based study","volume":"11","author":"Lee","year":"2023","journal-title":"Front. Public Health"},{"key":"10.1016\/j.envres.2025.121062_bib60","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tox.2017.05.015","article-title":"Cobalt toxicity in humans\u2014a review of the potential sources and systemic health effects","volume":"387","author":"Leyssens","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.envres.2025.121062_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125102","article-title":"Associations of prenatal exposure to vanadium with early-childhood growth: a prospective prenatal cohort study","volume":"411","author":"Li","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envres.2025.121062_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106762","article-title":"Association of prenatal exposure to cadmium with neurodevelopment in children at 2 years of age: the Japan Environment and Children's Study","volume":"156","author":"Ma","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.112448","article-title":"Association between prenatal metal exposure and adverse respiratory symptoms in childhood","volume":"205","author":"McRae","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib64","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/j.jaci.2021.10.001","article-title":"Advances in asthma: new understandings of asthma's natural history, risk factors, underlying mechanisms, and clinical management","volume":"148","author":"Miller","year":"2021","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.envres.2025.121062_bib65","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/cea.14022","article-title":"The impact of childhood asthma on academic performance: a matched population\u2010based cohort study","volume":"52","author":"Mitchell","year":"2022","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.envres.2025.121062_bib66","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1590\/s1806-37562016000000260","article-title":"Hard metal lung disease: a case series","volume":"42","author":"Mizutani","year":"2016","journal-title":"J. Bras. Pneumol."},{"key":"10.1016\/j.envres.2025.121062_bib67","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1542\/hpeds.2020-000950","article-title":"Depression and anxiety symptoms during and after pediatric asthma hospitalization","volume":"11","author":"Morin","year":"2021","journal-title":"Hosp. Pediatr."},{"key":"10.1016\/j.envres.2025.121062_bib68","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.scitotenv.2016.09.204","article-title":"Dietary predictors of urinary cadmium among pregnant women and children","volume":"575","author":"Moynihan","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.121062_bib69","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2019.00061","article-title":"Prenatal cadmium exposure is negatively associated with adiposity in girls not boys during adolescence","volume":"7","author":"Moynihan","year":"2019","journal-title":"Front. Public Health"},{"key":"10.1016\/j.envres.2025.121062_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12982-017-0062-6","article-title":"Model checking in multiple imputation: an overview and case study","volume":"14","author":"Nguyen","year":"2017","journal-title":"Emerg. Themes Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib71","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3390\/ijerph19010425","article-title":"Prenatal metal exposures and infants' developmental outcomes in a Navajo population","volume":"19","author":"Nozadi","year":"2021","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib72","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3390\/toxics10040157","article-title":"Global DNA methylation in cord blood as a biomarker for prenatal lead and antimony exposures","volume":"10","author":"Okamoto","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.envres.2025.121062_bib73","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.reprotox.2016.08.001","article-title":"Children's white blood cell counts in relation to developmental exposures to methylmercury and persistent organic pollutants","volume":"68","author":"Oulhote","year":"2017","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envres.2025.121062_bib74","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.3390\/ijerph7093332","article-title":"An examination of the association of selected toxic metals with total and central obesity indices: NHANES 99-02","volume":"7","author":"Padilla","year":"2010","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib75","doi-asserted-by":"crossref","first-page":"3048","DOI":"10.1038\/s41598-017-03106-z","article-title":"Prenatal chromium exposure and risk of preterm birth: a cohort study in Hubei, China","volume":"7","author":"Pan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envres.2025.121062_bib76","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.envint.2018.09.003","article-title":"Exposure to chromium during pregnancy and longitudinally assessed fetal growth: findings from a prospective cohort","volume":"121","author":"Peng","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib77","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/pai.13397","article-title":"Foetal exposure to heavy metals and risk of atopic diseases in early childhood","volume":"32","author":"Pesce","year":"2021","journal-title":"Pediatr. Allergy Immunol."},{"key":"10.1016\/j.envres.2025.121062_bib78","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3390\/ijerph19020722","article-title":"An overview of environmental risk factors for food allergy","volume":"19","author":"Peters","year":"2022","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib79","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S2213-2600(13)70277-7","article-title":"Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study","volume":"2","author":"Pinart","year":"2014","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.envres.2025.121062_bib80","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/jes.2015.16","article-title":"Placental arsenic concentrations in relation to both maternal and infant biomarkers of exposure in a US cohort","volume":"25","author":"Punshon","year":"2015","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2025.121062_bib81","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.112615","article-title":"Association between prenatal exposure to metal mixtures and early childhood allergic diseases","volume":"206","author":"Ruan","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib82","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph182413012","article-title":"Health risk assessment of exposure to 15 essential and toxic elements in Spanish women of reproductive age: a case study","volume":"18","author":"S\u00e1ez","year":"2021","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib83","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1093\/ajcn\/34.9.1676","article-title":"Urinary chromium excretion during pregnancy and its relationship with intravenous glucose loading","volume":"34","author":"Saner","year":"1981","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.envres.2025.121062_bib84","article-title":"Sant\u00e9 publique France","year":"2023","journal-title":"Asthme"},{"key":"10.1016\/j.envres.2025.121062_bib85","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/occmed\/kqq023","article-title":"Cobalt asthma -- a case series from a cobalt plant","volume":"60","author":"Sauni","year":"2010","journal-title":"Occup. Med."},{"key":"10.1016\/j.envres.2025.121062_bib86","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1097\/FTD.0b013e3181bb0ea1","article-title":"Defining a lowest observable adverse effect hair concentrations of mercury for neurodevelopmental effects of prenatal methylmercury exposure through maternal fish consumption: a systematic review","volume":"31","author":"Schoeman","year":"2009","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.envres.2025.121062_bib87","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1183\/16000617.00008114","article-title":"National and regional asthma programmes in Europe","volume":"24","author":"Selroos","year":"2015","journal-title":"Eur. Respir. Rev."},{"key":"10.1016\/j.envres.2025.121062_bib88","article-title":"Pediatric asthma: a global epidemic","volume":"85","author":"Serebrisky","year":"2019","journal-title":"Ann Glob Health"},{"key":"10.1016\/j.envres.2025.121062_bib89","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1183\/09031936.04.00117803","article-title":"Umbilical cord trace elements and minerals and risk of early childhood wheezing and eczema","volume":"24","author":"Shaheen","year":"2004","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.envres.2025.121062_bib90","series-title":"Encyclopedia of Metalloproteins","first-page":"641","article-title":"Chromium(III) and immune system","author":"Spears","year":"2013"},{"key":"10.1016\/j.envres.2025.121062_bib91","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.anai.2009.10.002","article-title":"From atopic dermatitis to asthma: the atopic march","volume":"105","author":"Spergel","year":"2010","journal-title":"Ann. Allergy Asthma Immunol."},{"key":"10.1016\/j.envres.2025.121062_bib92","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.b2393","article-title":"Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls","volume":"338","author":"Sterne","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.envres.2025.121062_bib93","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.3390\/ijerph7124267","article-title":"Antimony toxicity","volume":"7","author":"Sundar","year":"2010","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib94","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1513\/AnnalsATS.201409-432OC","article-title":"Reduced lung function in children associated with cesium 137 body burden","volume":"12","author":"Svendsen","year":"2015","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.envres.2025.121062_bib95","series-title":"The Nutritional Biochemistry of Chromium (III)","first-page":"251","article-title":"Benefits of chromium(III) complexes in animal and human health","author":"Swaroop","year":"2019"},{"key":"10.1016\/j.envres.2025.121062_bib96","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/jamanetworkopen.2021.31327","article-title":"Association between prenatal exposure to metals and atopic dermatitis among children aged 4 Years in taiwan","volume":"4","author":"Tsai","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.envres.2025.121062_bib97","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106243","article-title":"Maternal and childhood exposure to inorganic arsenic and airway allergy \u2013 a 15-Year birth cohort follow-up study","volume":"146","author":"Tsai","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib98","doi-asserted-by":"crossref","first-page":"5438","DOI":"10.3390\/ijerph17155438","article-title":"Chromium pollution in European water, sources, health risk, and remediation strategies: an overview","volume":"17","author":"Tumolo","year":"2020","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.envres.2025.121062_bib99","series-title":"Final Review of Scientific Information on Cadmium","year":"2010"},{"key":"10.1016\/j.envres.2025.121062_bib100","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1007\/s40572-016-0107-y","article-title":"Is urinary cadmium a biomarker of long-term exposure in humans? A review","volume":"3","author":"Vacchi-Suzzi","year":"2016","journal-title":"Curr Environ Health Rep"},{"key":"10.1016\/j.envres.2025.121062_bib101","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.envres.2006.08.003","article-title":"Gender differences in the disposition and toxicity of metals","volume":"104","author":"Vahter","year":"2007","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.121062_bib102","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/j.chemosphere.2015.10.006","article-title":"A case-control study of maternal exposure to chromium and infant low birth weight in China","volume":"144","author":"Xia","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.121062_bib103","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2020.115161","article-title":"Implications for prenatal cadmium exposure and adverse health outcomes in adulthood","volume":"403","author":"Young","year":"2020","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.envres.2025.121062_bib104","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1021\/acs.estlett.3c00142","article-title":"Antimony compounds associate with atopic dermatitis and influence models of itch and dysbiosis","volume":"10","author":"Zeldin","year":"2023","journal-title":"Environ. Sci. Technol. Lett."},{"key":"10.1016\/j.envres.2025.121062_bib105","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.envint.2018.11.072","article-title":"Antimony in urine during early pregnancy correlates with increased risk of gestational diabetes mellitus: a prospective cohort study","volume":"123","author":"Zhang","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.121062_bib106","first-page":"5","article-title":"The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma","author":"Zheng","year":"2014","journal-title":"J. Clin. Cell. Immunol."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125003135?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125003135?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T03:27:28Z","timestamp":1762140448000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935125003135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":106,"alternative-id":["S0013935125003135"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2025.121062","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prenatal exposure to heavy metals and childhood atopic disease","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2025.121062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"121062"}}