{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T14:32:28Z","timestamp":1793543548086,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373543"],"award-info":[{"award-number":["82373543"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103965"],"award-info":[{"award-number":["82103965"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82473721"],"award-info":[{"award-number":["82473721"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.envres.2025.122003","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T11:43:20Z","timestamp":1748519000000},"page":"122003","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Effects of PM2.5 constituents on gestational diabetes mellitus in Chinese pregnant women: The potential modifying role of vitamin B12"],"prefix":"10.1016","volume":"282","author":[{"given":"Chen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangbin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyang","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xumei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8359-3715","authenticated-orcid":false,"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2025.122003_bib1","first-page":"1802","article-title":"Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms","volume":"117","author":"Baccarelli","year":"2008","journal-title":"Circulation (New York, N. Y.)"},{"key":"10.1016\/j.envres.2025.122003_bib2","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.1002\/alz.12515","article-title":"B vitamin intakes modify the association between particulate air pollutants and incidence of all-cause dementia: findings from the Women's Health Initiative Memory Study","volume":"18","author":"Chen","year":"2022","journal-title":"Alzheimer's Dement."},{"key":"10.1016\/j.envres.2025.122003_bib3","doi-asserted-by":"crossref","first-page":"11859","DOI":"10.1021\/acs.est.5b02527","article-title":"Fine particulate matter constituents, nitric oxide synthase DNA methylation and exhaled nitric oxide","volume":"49","author":"Chen","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122003_bib4","first-page":"1","article-title":"Vitamin B12 and gestational diabetes mellitus: a systematic review and meta-analysis","author":"Chen","year":"2022","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.envres.2025.122003_bib5","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.2337\/dc23-S002","article-title":"On behalf of the American Diabetes Association, null, 2023. 2. Classification and diagnosis of diabetes: standards of care in diabetes","volume":"46","author":"ElSayed","year":"2023","journal-title":"Diabetes Care"},{"key":"10.1016\/j.envres.2025.122003_bib6","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1007\/s10661-022-10255-w","article-title":"Effect of portable air purifier on indoor air quality: reduced exposure to particulate matter and health risk assessment","volume":"194","author":"Fazlzadeh","year":"2022","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.envres.2025.122003_bib7","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1002\/jimd.12009","article-title":"Vitamin B12 , folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation","volume":"42","author":"Froese","year":"2019","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.envres.2025.122003_bib8","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/jdi.12854","article-title":"Prevalence of gestational diabetes mellitus in mainland China: a systematic review and meta-analysis","volume":"10","author":"Gao","year":"2019","journal-title":"J. Diabetes Investigat."},{"key":"10.1016\/j.envres.2025.122003_bib9","doi-asserted-by":"crossref","first-page":"12106","DOI":"10.1021\/acs.est.1c01863","article-title":"Tracking air pollution in China: near real-time PM2.5 retrievals from multisource data fusion","volume":"55","author":"Geng","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122003_bib10","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/bs.vh.2022.02.003","article-title":"Vitamin B12 deficiency","volume":"119","author":"Green","year":"2022","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.envres.2025.122003_bib11","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1289\/EHP212","article-title":"Exposure to fine particulate air pollution causes vascular insulin resistance by inducing pulmonary oxidative stress","volume":"124","author":"Haberzettl","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.122003_bib12","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1289\/ehp.1408456","article-title":"Association of atmospheric particulate matter and ozone with gestational diabetes mellitus","volume":"123","author":"Hu","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.122003_bib13","doi-asserted-by":"crossref","first-page":"11465","DOI":"10.1021\/acs.est.3c03280","article-title":"Association of fine particulate matter and its components with macrosomia: a nationwide birth cohort study of 336 Chinese cities","volume":"57","author":"Huang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122003_bib14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s12020-019-02053-1","article-title":"Vitamin B12 insufficiency is associated with increased risk of gestational diabetes mellitus: a systematic review and meta-analysis","volume":"66","author":"Kouroglou","year":"2019","journal-title":"Endocrine"},{"key":"10.1016\/j.envres.2025.122003_bib15","doi-asserted-by":"crossref","first-page":"169","DOI":"10.5603\/EP.2014.0023","article-title":"The IL-6\/IL-6R\/sgp130 system and Th17 associated cytokines in patients with gestational diabetes","volume":"65","author":"Ku\u017amicki","year":"2014","journal-title":"Endokrynol. Pol."},{"key":"10.1016\/j.envres.2025.122003_bib16","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1111\/1753-0407.12899","article-title":"Joint effects of folate and vitamin B12 imbalance with maternal characteristics on gestational diabetes mellitus","volume":"11","author":"Li","year":"2019","journal-title":"J. Diabetes"},{"key":"10.1016\/j.envres.2025.122003_bib17","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.3390\/nu14061169","article-title":"Associations of maternal rs1801131 genotype in MTHFR and serum folate and vitamin B12 with gestational diabetes mellitus in Chinese pregnant women","volume":"14","author":"Li","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.envres.2025.122003_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2023.114802","article-title":"Ambient air pollution and gestational diabetes mellitus: an updated systematic review and meta-analysis","volume":"255","author":"Liang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envres.2025.122003_bib19","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.envint.2019.01.005","article-title":"Air pollution and diabetes-related biomarkers in non-diabetic adults: a pathway to impaired glucose metabolism?","volume":"124","author":"Lucht","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.122003_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.118468","article-title":"Association of abnormal-glucose tolerance during pregnancy with exposure to PM2.5 components and sources","volume":"292","author":"Mai","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2025.122003_bib21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41572-019-0098-8","article-title":"Gestational diabetes mellitus","volume":"5","author":"McIntyre","year":"2019","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.envres.2025.122003_bib22","first-page":"1212","article-title":"Diagnostic criteria for gestational diabetes mellitus (WS331-2011)","volume":"125","year":"2012","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.envres.2025.122003_bib23","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.dsx.2019.12.001","article-title":"The chemical exposome of type 2 diabetes mellitus: opportunities and challenges in the omics era","volume":"14","author":"Misra","year":"2020","journal-title":"Diabetes Metabol. Syndr."},{"issue":"Suppl. 1","key":"10.1016\/j.envres.2025.122003_bib24","doi-asserted-by":"crossref","first-page":"S141","DOI":"10.1016\/j.dsx.2016.12.023","article-title":"Implication of homocysteine in diabetes and impact of folate and vitamin B12 in diabetic population","volume":"11","author":"Mursleen","year":"2017","journal-title":"Diabetes Metabol. Syndr."},{"key":"10.1016\/j.envres.2025.122003_bib25","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1164\/rccm.200708-1286OC","article-title":"Traffic-related particles are associated with elevated homocysteine: the VA normative aging study","volume":"178","author":"Park","year":"2008","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.envres.2025.122003_bib26","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1289\/ehp.1307711","article-title":"Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study","volume":"123","author":"Perez","year":"2015","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.122003_bib27","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/CIRCRESAHA.116.309279","article-title":"Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation","volume":"119","author":"Pope","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.envres.2025.122003_bib28","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/ejh.13571","article-title":"Review of vitamin B12 deficiency in pregnancy: a diagnosis not to miss as veganism and vegetarianism become more prevalent","volume":"106","author":"Rashid","year":"2021","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.envres.2025.122003_bib29","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1093\/aje\/kww007","article-title":"Placental nitrosative stress and exposure to ambient air pollution during gestation: a population study","volume":"184","author":"Saenen","year":"2016","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envres.2025.122003_bib30","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3390\/nu11030557","article-title":"The effects of vegetarian and vegan diet during pregnancy on the health of mothers and offspring","volume":"11","author":"Sebastiani","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.envres.2025.122003_bib31","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.scitotenv.2018.12.375","article-title":"Ammonia induces Treg\/Th1 imbalance with triggered NF-\u03baB pathway leading to chicken respiratory inflammation response","volume":"659","author":"Shi","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.122003_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2021.111864","article-title":"Surfaxin attenuates PM2.5-induced airway inflammation via restoring surfactant proteins in rats exposed to cigarette smoke","volume":"203","author":"Sun","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.122003_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106888","article-title":"Exposure to air pollutant mixture and gestational diabetes mellitus in southern California: results from electronic health record data of a large pregnancy cohort","volume":"158","author":"Sun","year":"2022","journal-title":"Environ. Int."},{"issue":"24","key":"10.1016\/j.envres.2025.122003_bib34","article-title":"Epidemiology and management of gestational diabetes","volume":"S0140\u20136736","author":"Sweeting","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.envres.2025.122003_bib35","doi-asserted-by":"crossref","first-page":"10172","DOI":"10.1021\/acs.est.1c08860","article-title":"Linking the fasting blood glucose level to short-term-exposed particulate constituents and pollution sources: results from a multicenter cross-sectional study in China","volume":"56","author":"Tian","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122003_bib36","article-title":"Progression to type 2 diabetes in women with a known history of gestational diabetes: systematic review and meta-analysis","volume":"369","author":"Vounzoulaki","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.envres.2025.122003_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.diabres.2021.109050","article-title":"IDF diabetes atlas: estimation of global and regional gestational diabetes mellitus prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group\u2019s Criteria","volume":"183","author":"Wang","year":"2022","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.envres.2025.122003_bib38","article-title":"Vitamin B12 and folate levels during pregnancy and risk of gestational diabetes mellitus: a systematic review and meta-analysis","volume":"8","author":"Wang","year":"2021","journal-title":"Front. Nutr."},{"key":"10.1016\/j.envres.2025.122003_bib39","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1093\/ije\/dyac022","article-title":"Ambient air pollution, healthy diet and vegetable intakes, and mortality: a prospective UK Biobank study","volume":"51","author":"Wang","year":"2022","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.envres.2025.122003_bib40","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1017\/S0007114523000314","article-title":"Serum folate mediates the associations of MTHFR rs1801133 polymorphism with blood glucose levels and gestational diabetes mellitus in Chinese Han pregnant women","volume":"130","author":"Wang","year":"2023","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.envres.2025.122003_bib41","first-page":"1140","article-title":"[Characteristics and Sources of PM2.5-O3 Compound Pollution in Tianjin]","volume":"43","author":"Xiao","year":"2022","journal-title":"Huanjing Kexue"},{"key":"10.1016\/j.envres.2025.122003_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162514","article-title":"Joint effect of ambient PM2.5 exposure and vitamin B12 during pregnancy on the risk of gestational diabetes mellitus","volume":"876","author":"Yang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.122003_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105880","article-title":"Fine particular matter and its constituents in air pollution and gestational diabetes mellitus","volume":"142","author":"Yu","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.122003_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.137349","article-title":"Ambient air pollution and gestational diabetes mellitus: a review of evidence from biological mechanisms to population epidemiology","volume":"719","author":"Zhang","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.122003_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106741","article-title":"Joint effect of urinary arsenic species and serum one-carbon metabolism nutrients on gestational diabetes mellitus: a cross-sectional study of Chinese pregnant women","volume":"156","author":"Zhang","year":"2021","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.122003_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.atmosenv.2022.119409","article-title":"PM2.5 constituents and onset of gestational diabetes mellitus: identifying susceptible exposure windows","volume":"291","author":"Zheng","year":"2022","journal-title":"Atmos. Environ."},{"key":"10.1016\/j.envres.2025.122003_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2020.110470","article-title":"Associations between the chemical composition of PM2.5 and gestational diabetes mellitus","volume":"198","author":"Zheng","year":"2021","journal-title":"Environ. Res."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512501254X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512501254X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T08:15:36Z","timestamp":1787213736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001393512501254X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":47,"alternative-id":["S001393512501254X"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2025.122003","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of PM2.5 constituents on gestational diabetes mellitus in Chinese pregnant women: The potential modifying role of vitamin B12","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2025.122003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"122003"}}