{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T08:14:15Z","timestamp":1780388055637,"version":"3.54.1"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009329","name":"Scientific Research and Technology Development Program of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","award":["\\u6842\\u79D1AD23026207"],"award-info":[{"award-number":["\\u6842\\u79D1AD23026207"]}],"id":[{"id":"10.13039\/501100009329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.envres.2025.122261","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T01:55:00Z","timestamp":1751421300000},"page":"122261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Chronic exposure to low concentration of metamifop induces reproductive endocrine disruption and courtship behavior disorders in zebrafish (Danio rerio)"],"prefix":"10.1016","volume":"284","author":[{"given":"Lu","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-2699","authenticated-orcid":false,"given":"Feng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihua","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihong","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2025.122261_bib1","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1139\/a06-005","article-title":"A review of bioconcentration factor (BCF) and bioaccumulation factor (BAF) assessments for organic chemicals in aquatic organisms","volume":"14","author":"Arnot","year":"2006","journal-title":"Environ. Rev."},{"key":"10.1016\/j.envres.2025.122261_bib2","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.chemosphere.2017.11.101","article-title":"Persistence behavior of metamifop and its metabolite in rice ecosystem","volume":"193","author":"Barik","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.122261_bib3","doi-asserted-by":"crossref","first-page":"9330","DOI":"10.1038\/s41598-021-87502-6","article-title":"Zebrafish automatic monitoring system for conditioning and behavioral analysis","volume":"11","author":"Barreiros","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envres.2025.122261_bib4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.aquatox.2018.02.016","article-title":"Azoles additively inhibit cytochrome P450 1 (EROD) and 19 (aromatase) in rainbow trout (Oncorhynchus mykiss)","volume":"198","author":"Beijer","year":"2018","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib5","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1021\/acs.est.8b05829","article-title":"Long-term exposure to environmental concentrations of azoxystrobin delays sexual development and alters reproduction in zebrafish (Danio rerio)","volume":"53","author":"Cao","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.etp.2011.08.007","article-title":"Effects of butachlor on reproduction and hormone levels in adult zebrafish (Danio rerio)","volume":"65","author":"Chang","year":"2013","journal-title":"Exp. Toxicol. Pathol."},{"key":"10.1016\/j.envres.2025.122261_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.155610","article-title":"Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior","volume":"838","author":"Chen","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2025.122261_bib8","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.chemosphere.2015.12.083","article-title":"Regulation of vitellogenin (vtg1) and estrogen receptor (er) gene expression in zebrafish (Danio rerio) following the administration of Cd(2)(+) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)","volume":"147","author":"Chen","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.122261_bib9","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/toxsci\/kfm003","article-title":"Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor","volume":"96","author":"Cheshenko","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2025.122261_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ygcen.2007.03.005","article-title":"Interference of endocrine disrupting chemicals with aromatase CYP19 expression or activity, and consequences for reproduction of teleost fish","volume":"155","author":"Cheshenko","year":"2008","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib11","volume":"vol. 7","author":"China","year":"2014"},{"key":"10.1016\/j.envres.2025.122261_bib12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1365-2826.2009.01835.x","article-title":"Oestrogen, kisspeptin, GPR54 and the pre-ovulatory luteinising hormone surge","volume":"21","author":"Clarkson","year":"2009","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib13","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.mce.2009.04.009","article-title":"Endocrine\/paracrine control of zebrafish ovarian development","volume":"312","author":"Clelland","year":"2009","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib14","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1021\/acs.est.6b06230","article-title":"Quantitative adverse outcome pathways and their application to predictive toxicology","volume":"51","author":"Conolly","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib15","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1210\/me.2004-0267","article-title":"Global gene expression analysis of estrogen receptor transcription factor cross talk in breast cancer: identification of estrogen-induced\/activator protein-1-dependent genes","volume":"19","author":"Denardo","year":"2005","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib16","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/toxsci\/kfz115","article-title":"Differential sensitivity to in vitro inhibition of cytochrome P450 aromatase (CYP19) activity among 18 freshwater fishes","volume":"170","author":"Doering","year":"2019","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.envres.2025.122261_bib17","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41574-023-00872-x","article-title":"The regulation of endocrine-disrupting chemicals to minimize their impact on health","volume":"19","author":"Duh-Leong","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib18","doi-asserted-by":"crossref","first-page":"3914","DOI":"10.1210\/en.2017-00429","article-title":"The two populations of kisspeptin neurons are involved in the ram-induced LH pulsatile secretion and LH surge in anestrous ewes","volume":"158","author":"Fabre-Nys","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.envres.2025.122261_bib19","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0303-7207(96)03960-3","article-title":"Transcriptional and post-transcriptional regulation of rainbow trout estrogen receptor and vitellogenin gene expression","volume":"124","author":"Flouriot","year":"1996","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib20","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.yhbeh.2008.04.004","article-title":"Testosterone control of male courtship in birds","volume":"54","author":"Fusani","year":"2008","journal-title":"Horm. Behav."},{"key":"10.1016\/j.envres.2025.122261_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.132928","article-title":"Non-negligible vector effect of micro(nano)plastics on tris(1,3-dichloro-2-propyl) phosphate in zebrafish quantified by toxicokinetic model","volume":"463","author":"Gao","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envres.2025.122261_bib22","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ygcen.2016.04.028","article-title":"Male-typical courtship, spawning behavior, and olfactory sensitivity are induced to different extents by androgens in the goldfish suggesting they are controlled by different neuroendocrine mechanisms","volume":"232","author":"Ghosal","year":"2016","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121461","article-title":"The kisspeptin-GnIH signaling pathway in the role of zebrafish courtship and aggressive behavior induced by azoxystrobin","volume":"325","author":"Guo","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2025.122261_bib24","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1002\/tox.20203","article-title":"Brain and gonadal aromatase as potential targets of endocrine disrupting chemicals in a model species, the zebrafish (Danio rerio)","volume":"21","author":"Hinfray","year":"2006","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib25","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1080\/02772248.2012.691502","article-title":"Determination of metamifop residues in soil under direct-seeded rice","volume":"94","author":"Janaki","year":"2012","journal-title":"Toxicol. Environ. Chem."},{"key":"10.1016\/j.envres.2025.122261_bib26","doi-asserted-by":"crossref","first-page":"8793","DOI":"10.1021\/es400329t","article-title":"Effects of bisphenol s exposure on endocrine functions and reproduction of zebrafish","volume":"47","author":"Ji","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib27","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41574-019-0273-8","article-title":"Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification","volume":"16","author":"La Merrill","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2020.105503","article-title":"Tributyltin impaired spermatogenesis and reproductive behavior in male zebrafish","volume":"224","author":"Lan","year":"2020","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib29","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1038\/s41592-022-01443-0","article-title":"Multi-animal pose estimation, identification and tracking with DeepLabCut","volume":"19","author":"Lauer","year":"2022","journal-title":"Nat. Methods"},{"key":"10.1016\/j.envres.2025.122261_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.131225","article-title":"Transcriptomic changes upon epoxiconazole exposure in a human stem cell-based model of developmental toxicity","volume":"284","author":"Lauschke","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.122261_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1582-4934.2012.01649.x","article-title":"Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors","volume":"17","author":"Lee","year":"2013","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.envres.2025.122261_bib32","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1080\/10807039.2015.1133242","article-title":"An international database for pesticide risk assessments and management","volume":"22","author":"Lewis","year":"2016","journal-title":"Hum. Ecol. Risk Assess."},{"key":"10.1016\/j.envres.2025.122261_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112417","article-title":"Xenopus laevis tadpoles exposed to metamifop: changes in growth, behavioral endpoints, neurotransmitters, antioxidant system and thyroid development","volume":"220","author":"Liu","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envres.2025.122261_bib34","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.envres.2025.122261_bib35","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.envres.2025.122261_bib36","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1126\/science.adp5936","article-title":"A single gene orchestrates androgen variation underlying male mating morphs in ruffs","volume":"387","author":"Loveland","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.envres.2025.122261_bib37","doi-asserted-by":"crossref","DOI":"10.3390\/toxics13030200","article-title":"Associations of environmental pollutant mixtures and red blood cell folate concentrations: a mixture analysis of the U.S. adult population based on NHANES data, 2007-2016","volume":"13","author":"Mascari","year":"2025","journal-title":"Toxics"},{"key":"10.1016\/j.envres.2025.122261_bib38","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/s41593-018-0209-y","article-title":"DeepLabCut: markerless pose estimation of user-defined body parts with deep learning","volume":"21","author":"Mathis","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.envres.2025.122261_bib39","doi-asserted-by":"crossref","DOI":"10.3139\/113.110173","article-title":"Nonionic surfactants: Octanol-water partition coefficients with the slow stirring\/surface tension method","author":"Miller","year":"2012","journal-title":"Tenside Surfactants Deterg."},{"key":"10.1016\/j.envres.2025.122261_bib40","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.mce.2005.11.031","article-title":"Multifunctionality of human 17beta-hydroxysteroid dehydrogenases","volume":"248","author":"Moeller","year":"2006","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib41","doi-asserted-by":"crossref","first-page":"R455","DOI":"10.1530\/ERC-16-0285","article-title":"Metabolic profiling of cholesterol and sex steroid hormones to monitor urological diseases","volume":"23","author":"Moon","year":"2016","journal-title":"Endocr. Relat. Cancer"},{"key":"10.1016\/j.envres.2025.122261_bib42","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.aquatox.2014.01.009","article-title":"Developmental exposure of zebrafish (Danio rerio) to bisphenol-S impairs subsequent reproduction potential and hormonal balance in adults","volume":"148","author":"Naderi","year":"2014","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib43","series-title":"OECD Guidelines for the Testing of Chemicals","article-title":"Test No.204: fish, prolonged toxicity test: 14-day study","year":"1984"},{"key":"10.1016\/j.envres.2025.122261_bib44","series-title":"Test No. 305: Bioaccumulation in Fish: Aqueous and Dietary Exposure","year":"2012"},{"key":"10.1016\/j.envres.2025.122261_bib45","series-title":"Test No. 203: Fish, Acute Toxicity Testing, OECD Guidelines for the Testing of Chemicals","year":"2019"},{"key":"10.1016\/j.envres.2025.122261_bib46","doi-asserted-by":"crossref","first-page":"373","DOI":"10.3390\/toxics3040373","article-title":"Hepatotoxicity, Nephrotoxicity and oxidative stress in rat testis following exposure to haloxyfop-p-methyl ester, an aryloxyphenoxypropionate herbicide","volume":"3","author":"Olayinka","year":"2015","journal-title":"Toxics"},{"key":"10.1016\/j.envres.2025.122261_bib47","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1177\/0748233716657763","article-title":"Fluazifop- p-butyl, an aryloxyphenoxypropionate herbicide, diminishes renal and hepatic functions and triggers testicular oxidative stress in orally exposed rats","volume":"33","author":"Ore","year":"2017","journal-title":"Toxicol. Ind. Health"},{"key":"10.1016\/j.envres.2025.122261_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpc.2022.109461","article-title":"Persistent and transgenerational effects of pesticide residues in zebrafish","volume":"262","author":"Pompermaier","year":"2022","journal-title":"Comp. Biochem. Physiol. C Toxicol. Pharmacol."},{"key":"10.1016\/j.envres.2025.122261_bib49","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.anbehav.2019.10.014","article-title":"Exposure to the ultraviolet filter benzophenone-3 (BP3) interferes with social behaviour in male Siamese fighting fish","volume":"158","author":"Portrais","year":"2019","journal-title":"Anim. Behav."},{"key":"10.1016\/j.envres.2025.122261_bib50","doi-asserted-by":"crossref","first-page":"14275","DOI":"10.1021\/acs.est.0c02871","article-title":"Exposure to boscalid induces reproductive toxicity of zebrafish by gender-specific alterations in steroidogenesis","volume":"54","author":"Qian","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib51","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.semcancer.2020.11.012","article-title":"LDL, HDL and endocrine-related cancer: from pathogenic mechanisms to therapies","volume":"73","author":"Revilla","year":"2021","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.envres.2025.122261_bib52","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s00128-018-2269-9","article-title":"Effect of pH on the transformation of a new readymix formulation of the herbicides bispyribac sodium and metamifop in water","volume":"100","author":"Saha","year":"2018","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib53","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.ygcen.2009.02.013","article-title":"Spermatogenesis in fish","volume":"165","author":"Schulz","year":"2010","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.envres.2025.122261_bib54","article-title":"Mitochondrial function in modulating human granulosa cell steroidogenesis and female fertility","volume":"21","author":"Sreerangaraja","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.envres.2025.122261_bib55","doi-asserted-by":"crossref","first-page":"11424","DOI":"10.1021\/acs.est.0c02639","article-title":"Structures of endocrine-disrupting chemicals determine binding to and activation of the estrogen receptor alpha and androgen receptor","volume":"54","author":"Tan","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib56","article-title":"Overexpression and knockdown of hypoxia-inducible factor 1 disrupt the expression of steroidogenic enzyme genes and early embryonic development in zebrafish","volume":"11","author":"Tan","year":"2017","journal-title":"Gene Regul. Syst. Biol."},{"key":"10.1016\/j.envres.2025.122261_bib57","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1021\/es404258h","article-title":"Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio)","volume":"48","author":"Uren","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.122261_bib58","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0887-2333(00)00018-7","article-title":"Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro","volume":"14","author":"Vinggaard","year":"2000","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.envres.2025.122261_bib60","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1002\/jat.3166","article-title":"Developmental toxicity and endocrine disruption of naphthenic acids on the early life stage of zebrafish (Danio rerio)","volume":"35","author":"Wang","year":"2015","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib59","first-page":"818","article-title":"Residue dynamics of metamifop 10% WP in rice","volume":"51","author":"Wang","year":"2012","journal-title":"Agrochemicals"},{"key":"10.1016\/j.envres.2025.122261_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2023.106515","article-title":"Comparison of developmental toxicity of benzophenone-3 and its metabolite benzophenone-8 in zebrafish","volume":"258","author":"Wang","year":"2023","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib62","doi-asserted-by":"crossref","DOI":"10.1038\/srep21337","article-title":"An embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring","volume":"6","author":"Wirbisky","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.envres.2025.122261_bib63","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2019.110003","article-title":"Computational and experimental investigations on the interactions of aryloxy-phenoxy-propionate herbicides to estrogen receptor alpha in zebrafish","volume":"189","author":"Xu","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.envres.2025.122261_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.120861","article-title":"Impacts of polystyrene microplastics on the behavior and metabolism in a marine demersal teleost, black rockfish (Sebastes schlegelii)","volume":"380","author":"Yin","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envres.2025.122261_bib65","article-title":"Transcriptome analysis revealed a positive role of ethephon on chlorophyll metabolism of Zoysia japonica under cold stress","volume":"11","author":"Zhang","year":"2022","journal-title":"Plants"},{"key":"10.1016\/j.envres.2025.122261_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133332","article-title":"Exposure of male adult zebrafish (Danio rerio) to triphenyl phosphate (TPhP) induces eye development disorders and disrupts neurotransmitter system-mediated abnormal locomotor behavior in larval offspring","volume":"465","author":"Zhang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.envres.2025.122261_bib67","article-title":"Metamifop as an estrogen-like chemical affects the pituitary-hypothalamic-gonadal (HPG) axis of female rice field eels (Monopterus albus)","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Physiol."},{"key":"10.1016\/j.envres.2025.122261_bib68","article-title":"Developmental toxicity and metabolomics analyses of zebrafish (Danio rerio) embryos exposed to fenoxaprop-p-ethyl","author":"Zhao","year":"2024","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.envres.2025.122261_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2021.105938","article-title":"Effects of sublethal concentration of metamifop on hepatic lipid metabolism in adult zebrafish (Danio rerio)","volume":"238","author":"Zhao","year":"2021","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.envres.2025.122261_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.135081","article-title":"Sub-lethal concentration of metamifop exposure impair gut health of zebrafish (Danio rerio)","volume":"303","author":"Zhao","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.122261_bib71","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.aquatox.2016.12.011","article-title":"Quizalofop-p-ethyl exposure increases estrogen axis activity in male and slightly decreases estrogen axis activity in female zebrafish (Danio rerio)","volume":"183","author":"Zhu","year":"2017","journal-title":"Aquat. Toxicol."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125015129?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125015129?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T04:47:04Z","timestamp":1776833224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935125015129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":71,"alternative-id":["S0013935125015129"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2025.122261","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chronic exposure to low concentration of metamifop induces reproductive endocrine disruption and courtship behavior disorders in zebrafish (Danio rerio)","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2025.122261","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"122261"}}