{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T11:08:34Z","timestamp":1785928114945,"version":"3.56.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3\/UH3OD023305"],"award-info":[{"award-number":["UG3\/UH3OD023305"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035516"],"award-info":[{"award-number":["UG3OD035516"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035518"],"award-info":[{"award-number":["UG3OD035518"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035532"],"award-info":[{"award-number":["UG3OD035532"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035521"],"award-info":[{"award-number":["UG3OD035521"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035529"],"award-info":[{"award-number":["UG3OD035529"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035550"],"award-info":[{"award-number":["UG3OD035550"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035509"],"award-info":[{"award-number":["UG3OD035509"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035517"],"award-info":[{"award-number":["UG3OD035517"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035519"],"award-info":[{"award-number":["UG3OD035519"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035537"],"award-info":[{"award-number":["UG3OD035537"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035508"],"award-info":[{"award-number":["UG3OD035508"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035544"],"award-info":[{"award-number":["UG3OD035544"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035536"],"award-info":[{"award-number":["UG3OD035536"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035543"],"award-info":[{"award-number":["UG3OD035543"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035527"],"award-info":[{"award-number":["UG3OD035527"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035542"],"award-info":[{"award-number":["UG3OD035542"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035540"],"award-info":[{"award-number":["UG3OD035540"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["UG3OD035513"],"award-info":[{"award-number":["UG3OD035513"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["U24OD023319"],"award-info":[{"award-number":["U24OD023319"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["U2COD023375"],"award-info":[{"award-number":["U2COD023375"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000052","name":"National Institutes of Health Office of the Director","doi-asserted-by":"publisher","award":["U24OD023382"],"award-info":[{"award-number":["U24OD023382"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000118","name":"National Institutes of Health Office of Behavioral and Social Sciences Research","doi-asserted-by":"publisher","award":["U24OD023319"],"award-info":[{"award-number":["U24OD023319"]}],"id":[{"id":"10.13039\/100000118","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.envres.2025.123597","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:01:49Z","timestamp":1766620909000},"page":"123597","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Association between gestational PFAS exposure biomarkers and risk of preeclampsia in the ECHO Cohort"],"prefix":"10.1016","volume":"292","author":[{"given":"Amber","family":"Cathey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Woodbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6891-7083","authenticated-orcid":false,"given":"Julia","family":"Varshavsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5176-4172","authenticated-orcid":false,"given":"Skarlet","family":"Velasquez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7296-738X","authenticated-orcid":false,"given":"Yeyi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akram","family":"Alshawabkeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Cordero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Velez-Vega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1892-3909","authenticated-orcid":false,"given":"Alicia","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Assiamira","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8357-5085","authenticated-orcid":false,"given":"John D.","family":"Meeker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2025.123597_bib1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3109\/10408444.2014.952400","article-title":"Perfluoroalkyl and polyfluoroalkyl substances and human fetal growth: a systematic review","volume":"45","author":"Bach","year":"2015","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.envres.2025.123597_bib2","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/s41390-021-01574-8","article-title":"The NIH ECHO program: investigating how early environmental influences affect child health","volume":"92","author":"Blaisdell","year":"2022","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.envres.2025.123597_bib3","series-title":"bkmr: Bayesian Kernel Machine Regression","article-title":"PACKAGE.BKMR","author":"Bobb","year":"2016"},{"key":"10.1016\/j.envres.2025.123597_bib4","doi-asserted-by":"crossref","first-page":"340.e1","DOI":"10.1016\/j.ajog.2022.10.006","article-title":"Fetal growth trajectories of babies born large-for-gestational age in the LIFECODES fetal growth study","volume":"228","author":"Bommarito","year":"2023","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.envres.2025.123597_bib5","doi-asserted-by":"crossref","DOI":"10.1289\/EHP9091","article-title":"Maternal levels of perfluoroalkyl substances (PFAS) during early pregnancy in relation to preeclampsia subtypes and biomarkers of preeclampsia risk","volume":"129","author":"Bommarito","year":"2021","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.123597_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105789","article-title":"Association of perfluoroalkyl substances with gestational hypertension and preeclampsia in the MIREC study","volume":"141","author":"Borghese","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.123597_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.reprotox.2024.108702","article-title":"Per- and polyfluoroalkyl substances (PFAS) and hypertensive disorders of Pregnancy- integration of epidemiological and mechanistic evidence","volume":"130","author":"Dangudubiyyam","year":"2024","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.envres.2025.123597_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107149","article-title":"Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: a systematic review","volume":"162","author":"DeLuca","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.123597_bib10","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/jalm\/jfaa149","article-title":"A critical review on the use of race in understanding racial disparities in preeclampsia","volume":"6","author":"Fasanya","year":"2021","journal-title":"J Appl Lab Med"},{"key":"10.1016\/j.envres.2025.123597_bib11","doi-asserted-by":"crossref","first-page":"585","DOI":"10.15585\/mmwr.mm7117a1","article-title":"Hypertensive disorders in pregnancy and mortality at delivery hospitalization \u2014 united States, 2017\u20132019","volume":"71","author":"Ford","year":"2022","journal-title":"MMWR Morb. Mortal. Wkly. Rep."},{"key":"10.1016\/j.envres.2025.123597_bib12","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1039\/D0EM00291G","article-title":"An overview of the uses of per- and polyfluoroalkyl substances (PFAS)","volume":"22","author":"Gl\u00fcge","year":"2020","journal-title":"Environ. Sci. Process. Impacts"},{"key":"10.1016\/j.envres.2025.123597_bib13","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.120723","article-title":"Placental polyamine metabolism differs by fetal sex, fetal growth restriction, and preeclampsia","volume":"3","author":"Gong","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.envres.2025.123597_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.133873","article-title":"Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes","volume":"295","author":"Hall","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.123597_bib15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/1047322X.1990.10389587","article-title":"Estimation of average concentration in the presence of nondetectable values","volume":"5","author":"Hornung","year":"1990","journal-title":"Appl. Occup. Environ. Hyg"},{"key":"10.1016\/j.envres.2025.123597_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.116064","article-title":"Perfluoroalkyl and polyfluoroalkyl substances and hypertensive disorders of pregnancy: a systematic review and meta-analysis","volume":"231","author":"Hu","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.123597_bib17","series-title":"qgcomp: Quantile G-Computation","article-title":"PACKAGE.QGCOMP","author":"Keil","year":"2019"},{"key":"10.1016\/j.envres.2025.123597_bib18","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.envint.2017.09.006","article-title":"Prenatal exposure to perfluoroalkyl substances and birth outcomes in a Spanish birth cohort","volume":"108","author":"Manzano-Salgado","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.123597_bib19","doi-asserted-by":"crossref","DOI":"10.1289\/EHP10723","article-title":"Birth outcomes in relation to prenatal exposure to Per- and polyfluoroalkyl substances and stress in the environmental influences on Child Health Outcomes (ECHO) program","volume":"131","author":"Padula","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.123597_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2022.107335","article-title":"Early-pregnancy plasma per- and polyfluoroalkyl substance (PFAS) concentrations and hypertensive disorders of pregnancy in the project viva cohort","volume":"165","author":"Preston","year":"2022","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.123597_bib21","doi-asserted-by":"crossref","DOI":"10.1289\/EHP11377","article-title":"Prenatal exposure to PFAS, associations with preterm birth and modification by maternal estrogen levels: the maoming birth study","volume":"131","author":"Qin","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.123597_bib22","series-title":"R: a Language and Environment for Statistical Computing","year":"2025"},{"key":"10.1016\/j.envres.2025.123597_bib23","author":"Rylander"},{"key":"10.1016\/j.envres.2025.123597_bib24","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1289\/ehp.1104752","article-title":"Relationship of perfluorooctanoic acid exposure to pregnancy outcome based on birth records in the mid-Ohio valley","volume":"120","author":"Savitz","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.123597_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.116967","article-title":"Prenatal per- and polyfluoroalkyl substances (PFAS) exposure in relation to preterm birth subtypes and size-for-gestational age in the LIFECODES cohort 2006-2008","volume":"237","author":"Siwakoti","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2025.123597_bib26","doi-asserted-by":"crossref","DOI":"10.1289\/EHP641","article-title":"Perfluoroalkyl substances during pregnancy and offspring weight and adiposity at birth: examining mediation by maternal fasting glucose in the healthy start study","volume":"125","author":"Starling","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2025.123597_bib27","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1093\/aje\/kwt432","article-title":"Perfluoroalkyl substances during pregnancy and validated preeclampsia among nulliparous women in the Norwegian mother and child cohort study","volume":"179","author":"Starling","year":"2014","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envres.2025.123597_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-12-818417-2.00023-3","article-title":"Epidemiology of hypertensive disorders in pregnancy","volume":"21\u201343","author":"Stuart","year":"2022","journal-title":"Chesley\u2019s Hypertensive Disorders in Pregnancy"},{"key":"10.1016\/j.envres.2025.123597_bib29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/s41370-018-0094-1","article-title":"A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects","volume":"29","author":"Sunderland","year":"2019","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.envres.2025.123597_bib30","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s40572-020-00279-0","article-title":"Perfluoroalkyl substances (PFAS) and their effects on the placenta, pregnancy, and child development: a potential mechanistic role for placental peroxisome proliferator-activated receptors (PPARs)","volume":"7","author":"Szilagyi","year":"2020","journal-title":"Curr. Environ. Health Rep."},{"key":"10.1016\/j.envres.2025.123597_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2024.142052","article-title":"Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and associations with hypertensive disorders of pregnancy in the Atlanta African American maternal-child cohort","volume":"357","author":"Thompson","year":"2024","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.123597_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137490","article-title":"In utero exposure to per-\/polyfluoroalkyl substances (PFASs): preeclampsia in pregnancy and low birth weight for neonates","volume":"313","author":"Tian","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.envres.2025.123597_bib33","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.envint.2014.11.013","article-title":"Hazard assessment of fluorinated alternatives to long-chain perfluoroalkyl acids (PFAAs) and their precursors: status quo, ongoing challenges and possible solutions","volume":"75","author":"Wang","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2025.123597_bib34","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1021\/acs.est.6b04806","article-title":"A never-ending story of Per- and polyfluoroalkyl substances (PFASs)?","volume":"51","author":"Wang","year":"2017","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2025.123597_bib35","author":"Wikstr\u00f6m"},{"key":"10.1016\/j.envres.2025.123597_bib36","article-title":"Association of early pregnancy perfluoroalkyl and polyfluoroalkyl substance exposure with birth outcomes","volume":"6","author":"Zhang","year":"2023","journal-title":"JAMA Netw. Open"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125028506?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935125028506?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T08:50:18Z","timestamp":1781686218000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935125028506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":35,"alternative-id":["S0013935125028506"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2025.123597","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between gestational PFAS exposure biomarkers and risk of preeclampsia in the ECHO Cohort","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2025.123597","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"123597"}}