{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:48:21Z","timestamp":1792054101075,"version":"4.4.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","award":["2020xkjT017"],"award-info":[{"award-number":["2020xkjT017"]}],"id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003424"],"award-info":[{"award-number":["82003424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.envres.2026.125744","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:42:52Z","timestamp":1790264572000},"page":"125744","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P1","title":["Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults"],"prefix":"10.1016","volume":"309","author":[{"given":"Liyan","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingxiu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weikang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cunzhong","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1506-6742","authenticated-orcid":false,"given":"Hua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5126-4335","authenticated-orcid":false,"given":"Dexiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3377-251X","authenticated-orcid":false,"given":"Zhijing","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.envres.2026.125744_bib1","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1164\/rccm.201010-1572OC","article-title":"An air filter intervention study of endothelial function among healthy adults in a woodsmoke-impacted community","volume":"183","author":"Allen","year":"2011","journal-title":"Am J Resp Crit Care"},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib2","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s13148-015-0078-0","article-title":"Platelet mitochondrial DNA methylation: a potential new marker of cardiovascular disease","volume":"7","author":"Baccarelli","year":"2015","journal-title":"Clin Epigenetics"},{"issue":"11","key":"10.1016\/j.envres.2026.125744_bib3","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1001\/jama.299.11.1265","article-title":"Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk","volume":"299","author":"Bhattacharyya","year":"2008","journal-title":"Jama-J Am Med Assoc"},{"issue":"4","key":"10.1016\/j.envres.2026.125744_bib4","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.003218","article-title":"Effects of air pollution and blood mitochondrial DNA methylation on markers of heart rate variability","volume":"5","author":"Byun","year":"2016","journal-title":"J. Am. Heart Assoc."},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib5","article-title":"The effect of high polycyclic aromatic hydrocarbon exposure on biological aging indicators","volume":"22","author":"Campisi","year":"2023","journal-title":"Environ Health-Glob"},{"key":"10.1016\/j.envres.2026.125744_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2025.109940","article-title":"Aged microplastics disrupted copper homeostasis to induce vascular toxicity: and human vascular organoids-basedstudy","volume":"206","author":"Chen","year":"2025","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2026.125744_bib7","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.envint.2016.06.026","article-title":"DNA hypomethylation and its mediation in the effects of fine particulate air pollution on cardiovascular biomarkers: a randomized crossover trial","volume":"94","author":"Chen","year":"2016","journal-title":"Environ. Int."},{"issue":"21","key":"10.1016\/j.envres.2026.125744_bib6","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1016\/j.jacc.2015.03.553","article-title":"Cardiopulmonary benefits of reducing indoor particles of outdoor origin: a randomized, double-blind crossover trial of air purifiers","volume":"65","author":"Chen","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13148-020-00825-5","article-title":"Platelet mitochondrial DNA methylation predicts future cardiovascular outcome in adults with overweight and obesity","volume":"12","author":"Corsi","year":"2020","journal-title":"Clin Epigenetics"},{"key":"10.1016\/j.envres.2026.125744_bib10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13148-017-0337-3","article-title":"Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue","volume":"9","author":"Devall","year":"2017","journal-title":"Clin Epigenetics"},{"issue":"3","key":"10.1016\/j.envres.2026.125744_bib11","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.numecd.2016.10.009","article-title":"8-Hydroxy-2-deoxyguanosine levels and heart failure: a systematic review and meta-analysis of the literature","volume":"27","author":"Di Minno","year":"2017","journal-title":"Nutr. Metabol. Cardiovasc. Dis."},{"issue":"11","key":"10.1016\/j.envres.2026.125744_bib12","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.molmed.2023.08.002","article-title":"The emerging janus face of SVEP1 in development and disease","volume":"29","author":"Elenbaas","year":"2023","journal-title":"Trends Mol. Med."},{"issue":"7","key":"10.1016\/j.envres.2026.125744_bib13","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.3390\/ijms20071599","article-title":"NFkappaB is a key player in the crosstalk between inflammation and cardiovascular diseases","volume":"20","author":"Fiordelisi","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.envres.2026.125744_bib14","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1038\/s42255-020-00287-2","article-title":"Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals","volume":"2","author":"Folkersen","year":"2020","journal-title":"Nat. Metab."},{"issue":"20","key":"10.1016\/j.envres.2026.125744_bib15","doi-asserted-by":"crossref","first-page":"14690","DOI":"10.1021\/acs.est.2c05534","article-title":"Short-term exposure of PM(2.5) and epigenetic aging: a quasi-experimental study","volume":"56","author":"Gao","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"10440","key":"10.1016\/j.envres.2026.125744_bib16","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/S0140-6736(24)00933-4","article-title":"Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990-2021: a systematic analysis for the global burden of disease study 2021","volume":"403","year":"2024","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.envres.2026.125744_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagen.2022.130188","article-title":"Role of platelet-derived growth factor c on endothelial dysfunction in cardiovascular diseases","volume":"1866","author":"Grismaldo","year":"2022","journal-title":"Bba-Gen Subjects"},{"issue":"Pt 1","key":"10.1016\/j.envres.2026.125744_bib18","article-title":"Aberrant mitochondrial DNA methylation and declined pulmonary function in a population with polycyclic aromatic hydrocarbon composition in particulate matter","volume":"214","author":"Guo","year":"2022","journal-title":"Environ. Res."},{"issue":"11","key":"10.1016\/j.envres.2026.125744_bib19","doi-asserted-by":"crossref","first-page":"7244","DOI":"10.1021\/acs.est.1c04488","article-title":"Associations of exposure to fine particulate matter mass and constituents with systemic inflammation: a cross-sectional study of urban older adults in China","volume":"56","author":"Han","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2026.125744_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijheh.2024.114348","article-title":"Longitudinal assessment of oxidative stress markers and their relationship with exposure to PM(2.5) and its bound metals in healthy participants","volume":"258","author":"Hsu","year":"2024","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.envres.2026.125744_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106859","article-title":"The acute effects of particulate matter air pollution on ambulatory blood pressure: a multicenter analysis at the hourly level","volume":"157","author":"Hu","year":"2021","journal-title":"Environ. Int."},{"issue":"15","key":"10.1016\/j.envres.2026.125744_bib22","doi-asserted-by":"crossref","first-page":"10589","DOI":"10.1021\/acs.est.1c02023","article-title":"Organic components of personal PM(2.5) exposure associated with inflammation: evidence from an untargeted exposomic approach","volume":"55","author":"Jiang","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.envres.2026.125744_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2024.108533","article-title":"Short-term effects of ambient gaseous air pollution on blood platelet mitochondrial DNA methylation and myocardial ischemia","volume":"185","author":"Jiang","year":"2024","journal-title":"Environ. Int."},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib24","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3390\/ijerph16010026","article-title":"Prenatal household air pollution alters cord blood mononuclear cell mitochondrial DNA copy number: sex-specific associations","volume":"16","author":"Kaali","year":"2018","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"12","key":"10.1016\/j.envres.2026.125744_bib25","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1038\/s41591-019-0673-2","article-title":"Undulating changes in human plasma proteome profiles across the lifespan","volume":"25","author":"Lehallier","year":"2019","journal-title":"Nat. Med."},{"issue":"30","key":"10.1016\/j.envres.2026.125744_bib27","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1093\/eurheartj\/ehac268","article-title":"Modifiable risk factors associated with cardiovascular disease and mortality in China: a PURE substudy","volume":"43","author":"Li","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.envres.2026.125744_bib26","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-019-0458-2","article-title":"Indoor nanoscale particulate matter-induced coagulation abnormality based on a human 3D microvascular model on a microfluidic chip","volume":"17","author":"Li","year":"2019","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.envres.2026.125744_bib28","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.scitotenv.2019.01.346","article-title":"Repeat dose exposure of PM(2.5) triggers the disseminated intravascular coagulation (DIC) in SD rats","volume":"663","author":"Liang","year":"2019","journal-title":"Sci. Total Environ."},{"issue":"24","key":"10.1016\/j.envres.2026.125744_bib29","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1161\/CIRCULATIONAHA.119.042054","article-title":"Pro-oxidative and proinflammatory effects after traveling from Los Angeles to beijing: a biomarker-based natural experiment","volume":"140","author":"Lin","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.envres.2026.125744_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.157000","article-title":"Short-term effects of personal exposure to temperature variability on cardiorespiratory health based on subclinical non-invasive biomarkers","volume":"843","author":"Lin","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.envres.2026.125744_bib31","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.ijheh.2019.05.005","article-title":"Ambient particulate air pollution and circulating C-reactive protein level: a systematic review and meta-analysis","volume":"222","author":"Liu","year":"2019","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.envres.2026.125744_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125963","article-title":"Effects of short-term personal exposure to air pollution on platelet mitochondrial DNA methylation levels and the potential mitigation by L-arginine supplementation","volume":"417","author":"Liu","year":"2021","journal-title":"J. Hazard Mater."},{"issue":"5","key":"10.1016\/j.envres.2026.125744_bib33","first-page":"860","article-title":"The relevance of coagulation in cardiovascular disease: what do the biomarkers tell Us?","volume":"112","author":"Lowe","year":"2014","journal-title":"Thromb. Haemost."},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib34","first-page":"1","article-title":"China cardiovascular diseases report 2018: an updated summary","volume":"17","author":"Ma","year":"2020","journal-title":"J Geriatr Cardiol"},{"key":"10.1016\/j.envres.2026.125744_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/ftox.2021.659407","article-title":"Association of prenatal ambient air pollution exposure with placental mitochondrial DNA copy number, telomere length and preeclampsia","volume":"3","author":"Mandakh","year":"2021","journal-title":"Front Toxicol"},{"issue":"1","key":"10.1016\/j.envres.2026.125744_bib36","doi-asserted-by":"crossref","DOI":"10.1007\/s10456-025-10023-7","article-title":"Hydroxychloroquine does not affect endotheliopathy or coagulopathy biomarkers in COVID-19: longitudinal results from the randomized trial","volume":"29","author":"Massonnaud","year":"2025","journal-title":"Angiogenesis"},{"key":"10.1016\/j.envres.2026.125744_bib37","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2022.1019965","article-title":"Residential greenness attenuated association of long-term air pollution exposure with elevated blood pressure: findings from polluted areas in northern China","volume":"10","author":"Mei","year":"2022","journal-title":"Front. Public Health"},{"key":"10.1016\/j.envres.2026.125744_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2025.123626","article-title":"N6-methyladenosine-dependent mechanisms in PM2.5 cardiorespiratory impairment: a randomized, double-blind crossover trial of air purifier","volume":"292","author":"Miao","year":"2026","journal-title":"Environ. Res."},{"key":"10.1016\/j.envres.2026.125744_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2019.102347","article-title":"Evidence of epigenetic alterations in thrombosis and coagulation: a systematic review","volume":"104","author":"Patsouras","year":"2019","journal-title":"J. Autoimmun."},{"issue":"11","key":"10.1016\/j.envres.2026.125744_bib40","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/CIRCRESAHA.116.309279","article-title":"Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation","volume":"119","author":"Pope","year":"2016","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.envres.2026.125744_bib41","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/ptr.6835","article-title":"Protective effect of supplementation with ginseng, lilii bulbus and poria against PM(2.5) in air pollution-induced cardiopulmonary damage among adults","volume":"35","author":"Qiu","year":"2021","journal-title":"Phytother Res."},{"issue":"24","key":"10.1016\/j.envres.2026.125744_bib42","doi-asserted-by":"crossref","first-page":"12671","DOI":"10.1039\/D1FO02913D","article-title":"Sesamin attenuates PM(2.5)-induced cardiovascular injury by inhibiting ferroptosis in rats","volume":"12","author":"Ren","year":"2021","journal-title":"Food Funct."},{"issue":"10384","key":"10.1016\/j.envres.2026.125744_bib43","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/S0140-6736(23)00215-5","article-title":"Inflammation and cholesterol as predictors of cardiovascular events among patients receiving Statin therapy: a collaborative analysis of three randomised trials","volume":"401","author":"Ridker","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.envres.2026.125744_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2019.108890","article-title":"Exposure to airborne fine particulate matter is associated with impaired endothelial function and biomarkers of oxidative stress and inflammation","volume":"180","author":"Riggs","year":"2020","journal-title":"Environ. Res."},{"issue":"25","key":"10.1016\/j.envres.2026.125744_bib45","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1016\/j.jacc.2020.11.010","article-title":"Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study","volume":"76","author":"Roth","year":"2020","journal-title":"J. Am. Coll. Cardiol."},{"issue":"6","key":"10.1016\/j.envres.2026.125744_bib46","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nrm3352","article-title":"Axis of ageing: telomeres, p53 and mitochondria","volume":"13","author":"Sahin","year":"2012","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.envres.2026.125744_bib47","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1093\/carcin\/bgac077","article-title":"Association between diesel exhaust exposure and mitochondrial DNA methylation","volume":"43","author":"Seow","year":"2022","journal-title":"Carcinogenesis"},{"issue":"3","key":"10.1016\/j.envres.2026.125744_bib48","doi-asserted-by":"crossref","first-page":"367","DOI":"10.5853\/jos.2021.00178","article-title":"Soluble CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable phenotype","volume":"23","author":"Shami","year":"2021","journal-title":"J Stroke"},{"issue":"10","key":"10.1016\/j.envres.2026.125744_bib49","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1093\/qjmed\/hch104","article-title":"Cardiovascular implications of exposure to traffic air pollution during exercise","volume":"97","author":"Sharman","year":"2004","journal-title":"Qjm-Int J Med"},{"issue":"11","key":"10.1016\/j.envres.2026.125744_bib50","doi-asserted-by":"crossref","DOI":"10.1289\/EHP9294","article-title":"Prospective associations of early pregnancy metal mixtures with mitochondria DNA copy number and telomere length in maternal and cord blood","volume":"129","author":"Smith","year":"2021","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.envres.2026.125744_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105579","article-title":"Short time exposure to ambient ozone and associated cardiovascular effects: a panel study of healthy young adults","volume":"137","author":"Song","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2026.125744_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2021.117215","article-title":"Associations of short-term PM(2.5) exposures with nasal oxidative stress, inflammation and lung function impairment and modification by GSTT1-null genotype: a panel study of the retired adults","volume":"285","author":"Sun","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2026.125744_bib53","article-title":"Platelet mitochondrial DNA methylation as epigenetic biomarker of short-term air pollution exposure in healthy subjects","volume":"8","author":"Sun","year":"2021","journal-title":"Front. Mol. Biosci."},{"issue":"7","key":"10.1016\/j.envres.2026.125744_bib54","doi-asserted-by":"crossref","first-page":"376","DOI":"10.3390\/medicina55070376","article-title":"Association between the No-Reflow phenomenon and soluble CD40 ligand level in patients with acute ST-Segment elevation myocardial infarction","volume":"55","author":"Tascanov","year":"2019","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.envres.2026.125744_bib55","article-title":"Association between ambient fine particulate pollution and hospital admissions for cause specific cardiovascular disease: time series study in 184 major Chinese cities","volume":"367","author":"Tian","year":"2019","journal-title":"Bmj"},{"key":"10.1016\/j.envres.2026.125744_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2021.106955","article-title":"Short- and intermediate-term exposure to ambient fine particulate elements and leukocyte epigenome-wide DNA methylation in older men: the normative aging study","volume":"158","author":"Wang","year":"2022","journal-title":"Environ. Int."},{"issue":"3","key":"10.1016\/j.envres.2026.125744_bib56","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/aje\/kwx277","article-title":"Possible mediation by methylation in acute inflammation following personal exposure to fine particulate air pollution","volume":"187","author":"Wang","year":"2018","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.envres.2026.125744_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105296","article-title":"Independent effect of main components in particulate matter on DNA methylation and DNA methyltransferase: a molecular epidemiology study","volume":"134","author":"Wang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.envres.2026.125744_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119026","article-title":"Sensitive inflammatory biomarkers of acute fine particulate matter exposure among healthy young adults: findings from a randomized, double-blind crossover trial on air filtration","volume":"301","author":"Wen","year":"2022","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.envres.2026.125744_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.162516","article-title":"Effects of indoor air purification intervention on blood pressure, blood-oxygen saturation, and heart rate variability: a double-blinded cross-over randomized controlled trial of healthy young adults","volume":"874","author":"Xia","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.envres.2026.125744_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102828","article-title":"Epigenetic modulation of Drp1-mediated mitochondrial fission by inhibition of S-adenosylhomocysteine hydrolase promotes vascular senescence and atherosclerosis","volume":"65","author":"You","year":"2023","journal-title":"Redox Biol."},{"issue":"13","key":"10.1016\/j.envres.2026.125744_bib62","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1073\/pnas.1618545114","article-title":"B vitamins attenuate the epigenetic effects of ambient fine particles in a pilot human intervention trial","volume":"114","author":"Zhong","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"8","key":"10.1016\/j.envres.2026.125744_bib63","doi-asserted-by":"crossref","first-page":"e210","DOI":"10.1161\/ATVBAHA.123.320005","article-title":"Molecular changes implicate angiogenesis and arterial remodeling in systemic sclerosis-associated and idiopathic pulmonary hypertension","volume":"44","author":"Zhou","year":"2024","journal-title":"Arterioscl Throm Vas"},{"key":"10.1016\/j.envres.2026.125744_bib64","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2023.139053","article-title":"Associations between exposure to ambient air pollution and changes in blood telomeres in young people: a repeated-measure study","volume":"336","author":"Zhu","year":"2023","journal-title":"Chemosphere"}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512602075X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001393512602075X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:20:59Z","timestamp":1792052459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001393512602075X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":64,"alternative-id":["S001393512602075X"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2026.125744","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2026.125744","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"125744"}}