{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:57:30Z","timestamp":1792616250256,"version":"4.5.0"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013314","name":"Higher Education Discipline Innovation Project","doi-asserted-by":"publisher","award":["D21027"],"award-info":[{"award-number":["D21027"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22161043"],"award-info":[{"award-number":["22161043"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.envres.2026.125856","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:16:04Z","timestamp":1791123364000},"page":"125856","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"P2","title":["Chromene-derived peroxynitrite fluorescent probes: From environmental water monitoring to oxidative stress assessment in living cells"],"prefix":"10.1016","volume":"309","author":[{"given":"Qingmao","family":"Long","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suorui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2649-8623","authenticated-orcid":false,"given":"Lianpeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqing","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanben","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.envres.2026.125856_bib1","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1124\/pr.120.019422","article-title":"On the clinical pharmacology of reactive oxygen species","volume":"72","author":"Casas","year":"2020","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.envres.2026.125856_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.342611","article-title":"A novel ESIPT fluorescent probe for early detection and assessment of ferroptosis-mediated acute kidney injury via peroxynitrite fluctuation","volume":"1308","author":"Chen","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.envres.2026.125856_bib3","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1021\/cb800279q","article-title":"Chemical biology of peroxynitrite: Kinetics, diffusion, and radicals","volume":"4","author":"Ferrer-Sueta","year":"2009","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.envres.2026.125856_bib4","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.4049\/jimmunol.0900831","article-title":"Peroxynitrite-dependent killing of cancer cells and presentation of released tumor antigens by activated dendritic cells","volume":"184","author":"Fraszczak","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.envres.2026.125856_bib5","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1039\/D5GC00080G","article-title":"Energy-efficient production of plasma-activated water: insights into controllable peroxynitrite chemistry","volume":"27","author":"Gan","year":"2025","journal-title":"Green Chem."},{"key":"10.1016\/j.envres.2026.125856_bib6","doi-asserted-by":"crossref","first-page":"3715","DOI":"10.1039\/D5GC00080G","article-title":"Energy-efficient production of plasma-activated water: insights into controllable peroxynitrite chemistry","volume":"27","author":"Gan","year":"2025","journal-title":"Green Chem."},{"key":"10.1016\/j.envres.2026.125856_bib7","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1039\/C3CS60271K","article-title":"Recent progress in the development of near-infrared fluorescent probes for bioimaging applications","volume":"43","author":"Guo","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.envres.2026.125856_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.134498","article-title":"Bright green cellulose-based fluorescent probe toward Au3+ smartphone technology recognition and its visualization application","volume":"277","author":"He","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.envres.2026.125856_bib9","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nrm3801","article-title":"Cellular mechanisms and physiological consequences of redox-dependent signalling","volume":"15","author":"Holmstr\u00f6m","year":"2014","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.envres.2026.125856_bib10","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1021\/ja206744z","article-title":"Photocontrollable peroxynitrite generator based on N -Methyl- N -nitrosoaminophenol for cellular application","volume":"134","author":"Ieda","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.envres.2026.125856_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.131847","article-title":"A dual-fluorophore and dual-site multifunctional fluorescent sensor for real-time visualization of mitochondrial ONOO-\/GSH cross-talk in living cells","volume":"365","author":"Jing","year":"2022","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.envres.2026.125856_bib12","doi-asserted-by":"crossref","first-page":"10004","DOI":"10.1039\/D4TB01446D","article-title":"Imaging of ONOO\u2212 fluctuations during drug-induced liver\/kidney injury in vitro and in vivo via a dicyanoisophorone-based NIR fluorescent probe with a large Stokes shift","volume":"12","author":"Kong","year":"2024","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.envres.2026.125856_bib13","doi-asserted-by":"crossref","first-page":"13629","DOI":"10.1039\/D4CC03452J","article-title":"Recent progress in organelle-targeting fluorescent probes for the detection of peroxynitrite","volume":"60","author":"Li","year":"2024","journal-title":"Chem. Commun."},{"key":"10.1016\/j.envres.2026.125856_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2024.124422","article-title":"High-throughput fluorescence quantification method based on inner filter effect and fluorescence imaging analysis","volume":"318","author":"Li","year":"2024","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.envres.2026.125856_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116233","article-title":"Multifunctional fluorescence probe for simultaneous detection of viscosity, polarity, and ONOO\u2212 and its bioimaging in vitro and vivo","volume":"254","author":"Li","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.envres.2026.125856_bib16","doi-asserted-by":"crossref","first-page":"6750","DOI":"10.1021\/acssensors.4c02452","article-title":"Monitoring endoplasmic reticulum peroxynitrite fluctuations in primary tendon-derived stem cells and insights into tendinopathy","volume":"9","author":"Liu","year":"2024","journal-title":"ACS Sens."},{"key":"10.1016\/j.envres.2026.125856_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.127909","article-title":"Preparation of mitochondrial targeted near-infrared ratio fluorescent probe and its dual response detection for viscosity and ONOO\u2212 and cell imaging","volume":"292","author":"Liu","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.envres.2026.125856_bib18","doi-asserted-by":"crossref","first-page":"6040","DOI":"10.1158\/0008-5472.CAN-18-0980","article-title":"Reactive oxygen and nitrogen species\u2013induced protein modifications: implication in carcinogenesis and anticancer therapy","volume":"78","author":"Moldogazieva","year":"2018","journal-title":"Cancer Res."},{"key":"10.1016\/j.envres.2026.125856_bib19","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1039\/D0AN00924E","article-title":"Novel \u201cturn on\u2013off\u201d paper sensor based on nonionic conjugated polythiophene-coated CdTe QDs for efficient visual detection of cholinesterase activity","volume":"145","author":"Ou","year":"2020","journal-title":"Analyst"},{"key":"10.1016\/j.envres.2026.125856_bib20","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/s12276-020-0384-2","article-title":"ROS in cancer therapy: the bright side of the moon","volume":"52","author":"Perillo","year":"2020","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.envres.2026.125856_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2025.103494","article-title":"Real-time monitoring of ONOO\u2212 in cerebral ischemia-reperfusion injury mouse models using a hydrazine-based NIR fluorescent probe","volume":"80","author":"Shang","year":"2025","journal-title":"Redox Biol."},{"key":"10.1016\/j.envres.2026.125856_bib22","doi-asserted-by":"crossref","first-page":"14860","DOI":"10.1021\/acs.analchem.4c02743","article-title":"Near-Infrared fluorescent probe reveals elevated mitochondrial viscosity during acute alcoholic liver injury","volume":"96","author":"Tan","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.envres.2026.125856_bib23","doi-asserted-by":"crossref","first-page":"8883","DOI":"10.1039\/C9CP00871C","article-title":"Fluorescence measurements of peroxynitrite\/peroxynitrous acid in cold air plasma treated aqueous solutions","volume":"21","author":"Tarabov\u00e1","year":"2019","journal-title":"Phys. Chem. Chem. Phys."},{"key":"10.1016\/j.envres.2026.125856_bib24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.tifs.2018.05.007","article-title":"Plasma activated water (PAW): chemistry, physico-chemical properties, applications in food and agriculture","volume":"77","author":"Thirumdas","year":"2018","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.envres.2026.125856_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.134094","article-title":"A highly sensitive and selective chemiluminescent probe for peroxynitrite detection in vitro, in vivo and in human liver cancer tissue","volume":"469","author":"Wang","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envres.2026.125856_bib26","doi-asserted-by":"crossref","first-page":"9289","DOI":"10.1007\/s10895-025-04255-5","article-title":"A new fluorescent probe based on carbazole-benzopyranyl for the recognition of ONOO\u2212 and its application","volume":"35","author":"Wang","year":"2025","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.envres.2026.125856_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123811","article-title":"An activatable fluorescent probe enables in vivo evaluation of peroxynitrite levels in rheumatoid arthritis","volume":"252","author":"Wang","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.envres.2026.125856_bib28","article-title":"Secondary activation on plasma-activated water by plasma-treated cotton for restoring and enhancing disinfection effect","volume":"480","author":"Wang","year":"2024","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.envres.2026.125856_bib29","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1039\/D3SC05010F","article-title":"Selective FRET nano probe based on carbon dots and naphthalimide\u2013isatin for the ratiometric detection of peroxynitrite in drug-induced liver injury","volume":"15","author":"Wu","year":"2024","journal-title":"Chem. Sci."},{"key":"10.1016\/j.envres.2026.125856_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2025.128064","article-title":"An \u0251-ketoamide-based fluorescent probe via aggregation induced emission for ONOO\u2212 detection in vivo","volume":"293","author":"Yan","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.envres.2026.125856_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2024.112409","article-title":"A long-wavelength fluorescent probe based on carbazole with AIE characteristics for the detection of ONOO\u2212 and its application","volume":"231","author":"Yang","year":"2024","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.envres.2026.125856_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2023.136449","article-title":"The H2S detection based on the combined smartphone technology and cellulose composite film and its application in biological imaging","volume":"1294","author":"Yuan","year":"2023","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.envres.2026.125856_bib33","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1007\/s11033-019-05211-w","article-title":"A practicable method to prepare nitrated proteins with peroxynitrite and low concentration of sodium hydroxide","volume":"47","author":"Zhang","year":"2020","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.envres.2026.125856_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.135679","article-title":"Rapid and sensitive detection of methyl parathion in rice based on carbon quantum dots nano-fluorescence probe and inner filter effect","volume":"413","author":"Zhang","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.envres.2026.125856_bib35","doi-asserted-by":"crossref","first-page":"8079","DOI":"10.1021\/acs.analchem.7b01580","article-title":"Reversible ratiometric fluorescent probe for sensing Bisulfate\/H2 O2 and its application in zebrafish","volume":"89","author":"Zhang","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.envres.2026.125856_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107729","article-title":"Development of a hybrid rhodamine-hydrazine NIR fluorescent probe for sensitive detection and imaging of peroxynitrite in necrotizing enterocolitis model","volume":"152","author":"Zhang","year":"2024","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.envres.2026.125856_bib37","doi-asserted-by":"crossref","first-page":"4180","DOI":"10.1021\/acs.analchem.3c05292","article-title":"Simultaneous visualization and depletion of peroxynitrite by a simple aggregation-induced emission nanoprobe for preventing breast cancer metastasis after surgery","volume":"96","author":"Zhang","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.envres.2026.125856_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.111540","article-title":"Near-infrared multi-functional aggregation-induced emission fluorescent probe for detection of viscosity and peroxynitrite and its imaging application","volume":"206","author":"Zhong","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.envres.2026.125856_bib39","doi-asserted-by":"crossref","first-page":"5276","DOI":"10.1039\/C8GC02800A","article-title":"Cold atmospheric plasma activated water as a prospective disinfectant: the crucial role of peroxynitrite","volume":"20","author":"Zhou","year":"2018","journal-title":"Green Chem."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935126021870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935126021870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:30:57Z","timestamp":1792614657000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935126021870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":39,"alternative-id":["S0013935126021870"],"URL":"https:\/\/doi.org\/10.1016\/j.envres.2026.125856","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chromene-derived peroxynitrite fluorescent probes: From environmental water monitoring to oxidative stress assessment in living cells","name":"articletitle","label":"Article Title"},{"value":"Environmental Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.envres.2026.125856","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"125856"}}