{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:35:20Z","timestamp":1790292920128,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Enzyme and Microbial Technology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.enzmictec.2013.12.010","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T19:01:04Z","timestamp":1387479664000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":58,"special_numbering":"C","title":["A new role for penicillin acylases: Degradation of acyl homoserine lactone quorum sensing signals by Kluyvera citrophila penicillin G acylase"],"prefix":"10.1016","volume":"56","author":[{"given":"Ruchira","family":"Mukherji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishant Kumar","family":"Varshney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyabrata","family":"Panigrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.G.","family":"Suresh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmita","family":"Prabhune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.enzmictec.2013.12.010_bib0005","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.enzmictec.2006.10.022","article-title":"A tryptophan residue is identified in the substrate binding of penicillin G acylase from Kluyvera citrophila","volume":"40","author":"Kumar","year":"2007","journal-title":"Enzyme Microb Tech"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0010","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0378-1119(86)90386-0","article-title":"Complete nucleotide sequence of the penicillin acylase gene from Kluyvera citrophila","volume":"49","author":"Barbero","year":"1986","journal-title":"Gene"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0015","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev.genet.35.102401.090913","article-title":"Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing","volume":"35","author":"Fuqua","year":"2001","journal-title":"Annu Rev Genet"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0020","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/cbic.200800521","article-title":"Quorum sensing and quorum quenching: the yin and yang of bacterial communication","volume":"10","author":"Uroz","year":"2009","journal-title":"Chembiochem"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0025","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1098\/rstb.2007.2045","article-title":"Quorum-quenching microbial infections: mechanisms and implications","volume":"362","author":"Dong","year":"2007","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0030","first-page":"101","article-title":"Quorum sensing and quorum-quenching enzymes","volume":"43","author":"Dong","year":"2005","journal-title":"J Microbiol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0035","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1073\/pnas.0911839107","article-title":"The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket","volume":"107","author":"Bokhove","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18388\/abp.2009_2512","article-title":"Quenching of acyl-homoserine lactone-dependent quorum sensing by enzymatic disruption of signal molecules","volume":"56","author":"Czajkowski","year":"2009","journal-title":"Acta Biochim Pol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0045","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF00156291","article-title":"Evaluation of determination of 6-amino penicillanic acid by p-dimethylaminobenzaldehyde","author":"Shewale","year":"1987","journal-title":"Biotechnol Tech l"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0050","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1021\/ac60223a034","article-title":"Automated colorimetric determination of 6-aminopenicillanic acid in fermentation media","volume":"37","author":"Bomstein","year":"1965","journal-title":"Anal Chem"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0055","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1107\/S174430911301943X","article-title":"Cloning, overexpression, crystallization and preliminary X-ray crystallographic analysis of a slow-processing mutant of penicillin G acylase from Kluyvera citrophila","volume":"69","author":"Varshney","year":"2013","journal-title":"Acta Cryst F"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0060","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1099\/00221287-143-12-3703","article-title":"Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones","volume":"143","author":"McClean","year":"1997","journal-title":"Microbiol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0065","first-page":"637","article-title":"Inhibition of bacterial quorum sensing by vanilla extract","volume":"42","author":"Choo","year":"2006","journal-title":"Lett Appl Microbiol"},{"issue":"2","key":"10.1016\/j.enzmictec.2013.12.010_bib0070","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"PROCHECK: a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J Appl Cryst"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0075","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1002\/pro.5560020916","article-title":"Verification of protein structures: patterns of nonbonded atomic interactions","volume":"2","author":"Colovos","year":"1993","journal-title":"Protein Sci"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0080","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/S0076-6879(97)77022-8","article-title":"VERIFY3D: assessment of protein models with three-dimensional profiles","volume":"277","author":"Eisenberg","year":"1997","journal-title":"Meth Enzymol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0085","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1046\/j.1365-2958.2003.03351.x","article-title":"Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching enzymes","volume":"47","author":"Lin","year":"2003","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0090","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0168-1656(02)00305-X","article-title":"Degradation of N-acylhomoserine lactones, the bacterial quorum-sensing molecules, by acylase","volume":"101","author":"Xu","year":"2003","journal-title":"J Biotechnol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0095","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1471-2180-9-89","article-title":"A probable aculeacin A acylase from the Ralstonia solanacearum GMI1000 is N-acyl-homoserine lactone acylase with quorum-quenching activity","volume":"9","author":"Chen","year":"2009","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0100","doi-asserted-by":"crossref","first-page":"2632","DOI":"10.1128\/AEM.71.5.2632-2641.2005","article-title":"Identification of extracellular N-acylhomoserine lactone acylase from a Streptomyces sp. and its application to quorum quenching","volume":"71","author":"Park","year":"2005","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.enzmictec.2013.12.010_bib0105","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1099\/mic.0.043935-0","article-title":"PA0305 of Pseudomonas aeruginosa is a quorum quenching acylhomoserine lactone acylase belonging to the Ntn hydrolase superfamily","volume":"157","author":"Wahjudi","year":"2011","journal-title":"Microbiol"}],"container-title":["Enzyme and Microbial Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141022913002561?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0141022913002561?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T04:59:19Z","timestamp":1564981159000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0141022913002561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":21,"alternative-id":["S0141022913002561"],"URL":"https:\/\/doi.org\/10.1016\/j.enzmictec.2013.12.010","relation":{},"ISSN":["0141-0229"],"issn-type":[{"value":"0141-0229","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A new role for penicillin acylases: Degradation of acyl homoserine lactone quorum sensing signals by Kluyvera citrophila penicillin G acylase","name":"articletitle","label":"Article Title"},{"value":"Enzyme and Microbial Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.enzmictec.2013.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}