{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T02:16:48Z","timestamp":1783563408542,"version":"3.55.0"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004242","name":"Princess Nourah bint Abdulrahman University","doi-asserted-by":"publisher","award":["PNURSP2025R460"],"award-info":[{"award-number":["PNURSP2025R460"]}],"id":[{"id":"10.13039\/501100004242","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Enzyme and Microbial Technology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.enzmictec.2025.110675","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T19:14:55Z","timestamp":1747941295000},"page":"110675","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Nano-azurin peptide as an inducer of innate immune responses"],"prefix":"10.1016","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3745-7456","authenticated-orcid":false,"given":"Nawal E.","family":"Al-Hazmi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0311-2975","authenticated-orcid":false,"given":"Hussam A.","family":"Althagafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3370-3899","authenticated-orcid":false,"given":"Fahad","family":"Alharthi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4662-3895","authenticated-orcid":false,"given":"Hind","family":"Althagafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6901-3104","authenticated-orcid":false,"given":"Deema","family":"Fallatah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3448-2958","authenticated-orcid":false,"given":"Jamilah","family":"Alshammari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7164-7838","authenticated-orcid":false,"given":"Deyala M.","family":"Naguib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.enzmictec.2025.110675_bib1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1007\/s12029-021-00654-6","article-title":"Microbial azurin immobilized on nano-chitosan as anticancer and antibacterial agent against gastrointestinal cancers and related bacteria","volume":"53","author":"Al-Hazmi","year":"2022","journal-title":"J. Gastrointest. Cancer"},{"key":"10.1016\/j.enzmictec.2025.110675_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/slct.202202633","article-title":"Modeling the interaction of anticancer protein azurin with the nanosheets for medical applications","volume":"7","author":"Atabay","year":"2022","journal-title":"ChemistrySelect"},{"key":"10.1016\/j.enzmictec.2025.110675_bib3","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s11033-024-10164-w","article-title":"Nano-bio-encapsulation of phyto-vaccines: a breakthrough in targeted cancer immunotherapy","volume":"52","author":"Ayyadurai","year":"2025","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.enzmictec.2025.110675_bib4","article-title":"Investigating the effect of rAzurin loaded mesoporous silica nanoparticles enwrapped with chitosan-folic acid on breast tumor regression in BALB\/C mice","volume":"300","author":"Barzelighi","year":"2025","journal-title":"Inter J. Biol. Macromol."},{"issue":"12","key":"10.1016\/j.enzmictec.2025.110675_bib5","doi-asserted-by":"crossref","first-page":"3871","DOI":"10.3390\/ijms19123871","article-title":"Perturbing the dynamics and organization of cell membrane components: a new paradigm for cancer-targeted therapies","volume":"19","author":"Bernardes","year":"2018","journal-title":"Inter J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.enzmictec.2025.110675_bib6","doi-asserted-by":"crossref","DOI":"10.1002\/eji.202451139","article-title":"Innate immunity champions: The diverse functions of macrophages","volume":"54","author":"Biscu","year":"2024","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/s41420-020-0255-6","article-title":"The role of neutrophil death in chronic inflammation and cancer","volume":"6","author":"Brostjan","year":"2020","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.enzmictec.2025.110675_bib8","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/s41392-024-02005-w","article-title":"Comprehensive snapshots of natural killer cells functions, signaling, molecular mechanisms and clinical utilization","volume":"9","author":"Chen","year":"2024","journal-title":"Signal Transduct. Target Ther."},{"key":"10.1016\/j.enzmictec.2025.110675_bib9","doi-asserted-by":"crossref","DOI":"10.1111\/imm.13899","article-title":"The role of innate immunity in healthy aging through antimicrobial peptides","author":"Cho","year":"2025","journal-title":"Immunol"},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202308174","article-title":"Landscape of the peripheral immune response induced by intraoperative radiotherapy combined with surgery in early breast cancer patients","volume":"12","author":"Dai","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.enzmictec.2025.110675_bib11","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1534823","article-title":"The role of M1\/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies","volume":"15","author":"Dousdampanis","year":"2025","journal-title":"Front Immunol."},{"issue":"13","key":"10.1016\/j.enzmictec.2025.110675_bib12","doi-asserted-by":"crossref","first-page":"7278","DOI":"10.3390\/ijms25137278","article-title":"Targeting macrophage polarization for reinstating homeostasis following tissue damage","volume":"25","author":"Du","year":"2024","journal-title":"Inter. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.enzmictec.2025.110675_bib13","doi-asserted-by":"crossref","first-page":"515","DOI":"10.3390\/ijms26020515","article-title":"Targeting triple NK cell suppression mechanisms: a comprehensive review of biomarkers in pancreatic cancer therapy","volume":"26","author":"Fanijavadi","year":"2025","journal-title":"Inter J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.enzmictec.2025.110675_bib14","doi-asserted-by":"crossref","first-page":"521","DOI":"10.3390\/cells13060521","article-title":"TNF-related apoptosis-inducing ligand: non-apoptotic signalling","volume":"13","author":"Guerrache","year":"2024","journal-title":"Cells"},{"key":"10.1016\/j.enzmictec.2025.110675_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.it.2024.12.006","article-title":"Immune evasion in ovarian cancer: implications for immunotherapy and emerging treatments","author":"Gupta","year":"2025","journal-title":"Trend Immunol."},{"issue":"4","key":"10.1016\/j.enzmictec.2025.110675_bib16","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/0891-5849(94)00181-I","article-title":"Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing","volume":"18","author":"Hampton","year":"1995","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.enzmictec.2025.110675_bib17","first-page":"245","article-title":"The immune-modulator activity of Pseudomonas aeruginosa extracted protein: Azurin Charming Protein","volume":"42","author":"Hassan","year":"2023","journal-title":"Lat. Am. J. Pharm."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e23790","article-title":"Phytoimmunomodulators: a review of natural modulators for complex immune system","volume":"10","author":"Hooda","year":"2024","journal-title":"Heliyon"},{"issue":"8","key":"10.1016\/j.enzmictec.2025.110675_bib19","first-page":"76","article-title":"Nano-encapsulation of proteins and peptides","volume":"2","author":"Ibrahim","year":"2017","journal-title":"Curr. Nanomater."},{"issue":"7","key":"10.1016\/j.enzmictec.2025.110675_bib20","doi-asserted-by":"crossref","first-page":"5789","DOI":"10.3168\/jds.2017-14355","article-title":"Enhanced phagocytosis of Aggregatibacter actinomycetemcomitans cells by macrophages activated by a probiotic Lactobacillus strain","volume":"101","author":"Jaffar","year":"2018","journal-title":"J. Dairy Sci."},{"issue":"15","key":"10.1016\/j.enzmictec.2025.110675_bib21","doi-asserted-by":"crossref","first-page":"8581","DOI":"10.3390\/ijms23158581","article-title":"Nanofiber carriers of therapeutic load: current trends","volume":"23","author":"Jarak","year":"2022","journal-title":"Inter J. Mol. Sci."},{"key":"10.1016\/j.enzmictec.2025.110675_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1420205","article-title":"The basic biology of NK cells and its application in tumor immunotherapy","volume":"15","author":"Jiang","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib23","series-title":"Role of Medicinal Plants in Autoimmune Diseases","first-page":"15","article-title":"Cells of the immune system and their multifunctional roles","author":"John","year":"2025"},{"issue":"24","key":"10.1016\/j.enzmictec.2025.110675_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/smll.202306738","article-title":"Surface Engineering of Natural Killer Cells with CD44-targeting Ligands for Augmented Cancer Immunotherapy","volume":"20","author":"Kim","year":"2024","journal-title":"Small"},{"issue":"16-18","key":"10.1016\/j.enzmictec.2025.110675_bib25","doi-asserted-by":"crossref","DOI":"10.1089\/ars.2022.0220","article-title":"Nitric oxide: regulation and function in neutrophil immune responses","volume":"40","author":"Kumar","year":"2024","journal-title":"Antioxid. Redox Sign"},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib26","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.62110\/sciencein.cbl.2025.v12.1253","article-title":"Antimicrobial peptides in tuberculosis: insights into the immunomodulatory mechanisms","volume":"12","author":"Kumari","year":"2025","journal-title":"Chem. Biol. Lett."},{"key":"10.1016\/j.enzmictec.2025.110675_bib27","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12985-024-02287-0","article-title":"Unraveling the dynamic mechanisms of natural killer cells in viral infections: insights and implications","volume":"21","author":"Letafati","year":"2025","journal-title":"Virol. J."},{"issue":"2","key":"10.1016\/j.enzmictec.2025.110675_bib28","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3390\/toxics13020095","article-title":"Fluoride-mediated immune damage through cytokine network regulation of tregs","volume":"13","author":"Liu","year":"2025","journal-title":"Toxics"},{"issue":"3","key":"10.1016\/j.enzmictec.2025.110675_bib29","doi-asserted-by":"crossref","first-page":"384","DOI":"10.3390\/cancers17030384","article-title":"Neutrophil engulfment in cancer: friend or foe?","volume":"17","author":"Lu","year":"2025","journal-title":"Cancers"},{"key":"10.1016\/j.enzmictec.2025.110675_bib30","article-title":"Macrophage polarization: an important role in inflammatory diseases","volume":"15","author":"Luo","year":"2024","journal-title":"Front Immunol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib31","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12943-025-02228-7","article-title":"Bidirectional role of neutrophils in tumor development","volume":"24","author":"Luyang","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.enzmictec.2025.110675_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.134778","article-title":"Microbial natural compounds and secondary metabolites as Immunomodulators: a review","volume":"278","author":"Mahmoudi","year":"2024","journal-title":"Inter J. Biol. Macromol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib33","article-title":"At the crossroads of TNF \u03b1 signaling and cancer","volume":"17","author":"Manohar","year":"2025","journal-title":"Curr. Mol. Pharm."},{"key":"10.1016\/j.enzmictec.2025.110675_bib34","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1359600","article-title":"ROS signaling in innate immunity via oxidative protein modifications","volume":"15","author":"Manoharan","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib35","article-title":"Plasmacytoid dendritic cell sensing of African swine fever virus\u2013infected macrophages results in STING-dependent robust interferon-\u03b1 production","author":"Mar\u00eda","year":"2025","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib36","doi-asserted-by":"crossref","first-page":"2","DOI":"10.3390\/ijms26010002","article-title":"Cancer-targeting applications of cell-penetrating peptides","volume":"26","author":"Moreno-Vargas","year":"2025","journal-title":"Inter J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/07357907.2024.2445528","article-title":"A comprehensive insight into apoptosis: molecular mechanisms, signaling pathways, and modulating therapeutics","volume":"43","author":"Mosadegh","year":"2025","journal-title":"Cancer Invest."},{"key":"10.1016\/j.enzmictec.2025.110675_bib38","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.01690","article-title":"Regulatory interactions between neutrophils, tumor cells and T cells","volume":"10","author":"Oberg","year":"2019","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.enzmictec.2025.110675_bib39","article-title":"Intercellular adhesion molecule-1 (ICAM-1): from molecular functions to clinical applications in cancer investigation","volume":"1879","author":"Qian","year":"2024","journal-title":"BBA- Rev. Cancer"},{"key":"10.1016\/j.enzmictec.2025.110675_bib40","article-title":"Naturally derived bioactive compounds as precision modulators of immune and inflammatory mechanisms in psoriatic conditions","author":"Radu","year":"2024","journal-title":"Inflammopharmacol"},{"key":"10.1016\/j.enzmictec.2025.110675_bib41","series-title":"Handbook of Cancer and Immunology","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-032-00767-4_194","article-title":"Harnessing Natural Killer Cells for Cancer Therapy","author":"Rajalingam","year":"2025"},{"issue":"6","key":"10.1016\/j.enzmictec.2025.110675_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/toxres\/tfae179","article-title":"Design and computational analysis of a novel Azurin-BR2 chimeric protein against breast cancer","volume":"13","author":"Rehman","year":"2024","journal-title":"Toxicol. Res"},{"key":"10.1016\/j.enzmictec.2025.110675_bib43","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s10555-025-10242-w","article-title":"The diversity of natural killer cell functional and phenotypic states in cancer","volume":"44","author":"Rishabh","year":"2025","journal-title":"Cancer Metastas-.-. Rev."},{"key":"10.1016\/j.enzmictec.2025.110675_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.117794","article-title":"The immunomodulatory potential of chickpea protein hydrolysate via ROS and NO pathways","volume":"182","author":"Rodr\u00edguez-Mart\u00edn","year":"2025","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3390\/ph18010075","article-title":"Leveraging single-cell multi-omics to decode tumor microenvironment diversity and therapeutic resistance","volume":"18","author":"Sabit","year":"2025","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.enzmictec.2025.110675_bib46","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s10522-024-10152-4","article-title":"The dichotomic role of cytokines in aging","volume":"26","author":"Silva","year":"2025","journal-title":"Biogerontol"},{"key":"10.1016\/j.enzmictec.2025.110675_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fntpr.2024.1470639","article-title":"Boosting the human antiviral response in conjunction with natural plant products","volume":"3","author":"Srivastava","year":"2025","journal-title":"Front Nat. Prod."},{"key":"10.1016\/j.enzmictec.2025.110675_bib48","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s12026-024-09577-3","article-title":"The effects of bone marrow humoral components of B-cell acute lymphoblastic leukemia patients on natural killer cell suppression","volume":"73","author":"Tahrali","year":"2025","journal-title":"Immunol. Res"},{"key":"10.1016\/j.enzmictec.2025.110675_bib49","doi-asserted-by":"crossref","DOI":"10.1093\/cei\/uxae126","article-title":"The role of neutrophils in allergic disease","volume":"219","author":"Trayer","year":"2025","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.enzmictec.2025.110675_bib50","article-title":"Plant-derived bioactive compounds as key players in the modulation of immune-related conditions","author":"Vieira","year":"2024","journal-title":"Phytochem Rev."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib51","doi-asserted-by":"crossref","first-page":"230","DOI":"10.3390\/microorganisms12010230","article-title":"Natural killer cells and cytotoxic T cells: complementary partners against microorganisms and cancer","volume":"12","author":"Vojdani","year":"2024","journal-title":"Microorganism"},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib52","doi-asserted-by":"crossref","DOI":"10.1111\/1750-3841.17672","article-title":"Oral barriers to food-derived active peptides and nano-delivery strategies","volume":"90","author":"Wang","year":"2025","journal-title":"J. Food Sci."},{"key":"10.1016\/j.enzmictec.2025.110675_bib53","first-page":"273","article-title":"Role of bacteria in cancers and their therapeutic potential: Review of current knowledge","volume":"28","author":"Wawrety","year":"2025","journal-title":"Iran. J. Basic Med Sci."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1012821","article-title":"Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance","volume":"21","author":"Widziolek","year":"2025","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.enzmictec.2025.110675_bib55","article-title":"The role of interleukin-1 beta in inflammation and the potential of immune-targeted therapies","volume":"3","author":"Wijdan","year":"2025","journal-title":"Pharm. Res-Rep."},{"issue":"2","key":"10.1016\/j.enzmictec.2025.110675_bib56","doi-asserted-by":"crossref","first-page":"112","DOI":"10.3390\/pathogens14020112","article-title":"Pathogenic and protective roles of neutrophils in chlamydia trachomatis infection","volume":"14","author":"Wilton","year":"2025","journal-title":"Pathogens"},{"key":"10.1016\/j.enzmictec.2025.110675_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.cytogfr.2025.01.001","article-title":"Interleukin-6 (IL-6)-associated tumor microenvironment remodelling and cancer immunotherapy","author":"Wu","year":"2025","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.enzmictec.2025.110675_bib58","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2147\/OTT.S486411","article-title":"Research progress of NK cells in glioblastoma treatment","volume":"18","author":"Wu","year":"2025","journal-title":"OncoTarget Ther."},{"key":"10.1016\/j.enzmictec.2025.110675_bib59","series-title":"An Interplay of Cellular and Molecular Components of Immunology","first-page":"27","article-title":"Innate Immunity","author":"Yadav","year":"2022"},{"key":"10.1016\/j.enzmictec.2025.110675_bib60","doi-asserted-by":"crossref","first-page":"3392","DOI":"10.1038\/s41598-025-86130-8","article-title":"Advances and prospects of cell-penetrating peptides in tumor immunotherapy","volume":"15","author":"Yang","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.enzmictec.2025.110675_bib61","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s00018-024-05155-w","article-title":"MDSC-derived S100A8\/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells","volume":"81","author":"Yang","year":"2024","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.enzmictec.2025.110675_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.hlife.2025.01.003","article-title":"Neutrophils: key players in the metabolic syndrome puzzle","author":"Yaw","year":"2025","journal-title":"HLife"},{"key":"10.1016\/j.enzmictec.2025.110675_bib63","first-page":"53","article-title":"Interleukin-1 beta in psychosocial stress","author":"Yin","year":"2024","journal-title":"Stress.: Immunol. Inflamm."},{"key":"10.1016\/j.enzmictec.2025.110675_bib64","doi-asserted-by":"crossref","first-page":"3735","DOI":"10.1038\/s41598-025-86649-w","article-title":"Azurin a potent anticancer and antimicrobial agent isolated from a novel Pseudomonas aeruginosa strain","volume":"15","author":"Zaghloul","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.enzmictec.2025.110675_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2024.113386","article-title":"Therapeutic peptides targeting intracellular molecules","volume":"219","author":"Zaman","year":"2024","journal-title":"Eur. Polym. J."},{"issue":"1","key":"10.1016\/j.enzmictec.2025.110675_bib66","first-page":"1","article-title":"Mucosal immune response in biology, disease prevention and treatment","volume":"10","author":"Zhou","year":"2025","journal-title":"Signal Transduct. Target Ther."},{"key":"10.1016\/j.enzmictec.2025.110675_bib67","article-title":"The Innate Immune Sensor Zbp1 Mediates Central Nervous System Inflammation Induced by Angiostrongylus cantonensis by Promoting Macrophage Inflammatory Phenotypes","author":"Zhou","year":"2025","journal-title":"Adv. Sc."}],"container-title":["Enzyme and Microbial Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014102292500095X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014102292500095X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T05:25:32Z","timestamp":1762233932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014102292500095X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":67,"alternative-id":["S014102292500095X"],"URL":"https:\/\/doi.org\/10.1016\/j.enzmictec.2025.110675","relation":{},"ISSN":["0141-0229"],"issn-type":[{"value":"0141-0229","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nano-azurin peptide as an inducer of innate immune responses","name":"articletitle","label":"Article Title"},{"value":"Enzyme and Microbial Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.enzmictec.2025.110675","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110675"}}