{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T13:58:58Z","timestamp":1761919138798,"version":"build-2065373602"},"reference-count":24,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.eplepsyres.2008.08.005","type":"journal-article","created":{"date-parts":[[2008,9,20]],"date-time":"2008-09-20T04:50:54Z","timestamp":1221886254000},"page":"219-222","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":89,"title":["Ketamine successfully terminates malignant status epilepticus"],"prefix":"10.1016","volume":"82","author":[{"given":"Harald","family":"Pr\u00fcss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Holtkamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2008.08.005_bib1","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1001\/archneur.59.2.188","article-title":"Refractory status epilepticus in 2001","volume":"59","author":"Bleck","year":"2002","journal-title":"Arch. Neurol."},{"issue":"Suppl. 1","key":"10.1016\/j.eplepsyres.2008.08.005_bib2","first-page":"282","article-title":"Electroencephalographic effects of ketamine treatment for refractory status epilepticus","volume":"43","author":"Bleck","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0920-1211(00)00175-3","article-title":"Ketamine controls prolonged status epilepticus","volume":"42","author":"Borris","year":"2000","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib4","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1046\/j.1528-1157.2002.28501.x","article-title":"Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic review","volume":"43","author":"Claassen","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib5","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1212\/WNL.55.5.693","article-title":"Incidence of status epilepticus in French-speaking Switzerland: (EPISTAR)","volume":"55","author":"Coeytaux","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib6","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1212\/WNL.46.4.1029","article-title":"A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia","volume":"46","author":"DeLorenzo","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib7","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1001\/archneur.62.9.1428","article-title":"A \u201cmalignant\u201d variant of status epilepticus","volume":"62","author":"Holtkamp","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib8","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1136\/jnnp.2004.041947","article-title":"Predictors and prognosis of refractory status epilepticus treated in a neurological intensive care unit","volume":"76","author":"Holtkamp","year":"2005","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib9","doi-asserted-by":"crossref","first-page":"7532","DOI":"10.1523\/JNEUROSCI.17-19-07532.1997","article-title":"Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors","volume":"17","author":"Kapur","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib10","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1097\/00000542-200612000-00018","article-title":"Inhibition of glutamatergic activation of extracellular signal-regulated protein kinases in hippocampal neurons by the intravenous anesthetic propofol","volume":"105","author":"Kozinn","year":"2006","journal-title":"Anesthesiology"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/BF03022615","article-title":"Effect of thiopental sodium on N-methyl-d-aspartate-gated currents","volume":"53","author":"Liu","year":"2006","journal-title":"Can. J. Anaesth."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib12","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1212\/WNL.43.3_Part_1.483","article-title":"Status epilepticus at an urban public hospital in the 1980s","volume":"43","author":"Lowenstein","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib13","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1111\/j.1528-1167.2007.01384.x","article-title":"A combination of ketamine and diazepam synergistically controls refractory status epilepticus induced by cholinergic stimulation.","volume":"49","author":"Martin","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib14","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0304-3940(99)00238-4","article-title":"N-methyl-d-asparate receptor antagonists abolish the maintenance phase of self-sustaining status epilepticus in rat","volume":"265","author":"Mazarati","year":"1999","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib15","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S1474-4422(07)70074-1","article-title":"Non-convulsive status epilepticus in adults: clinical forms and treatment","volume":"6","author":"Meierkord","year":"2007","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib16","doi-asserted-by":"crossref","first-page":"7724","DOI":"10.1523\/JNEUROSCI.4944-04.2005","article-title":"Trafficking of GABA(A) receptors, loss of inhibition, and a mechanism for pharmacoresistance in status epilepticus","volume":"25","author":"Naylor","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib17","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0306-4522(99)00132-3","article-title":"N-methyl-d-aspartate receptor activation regulates refractoriness of status epilepticus to diazepam","volume":"93","author":"Rice","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib18","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1001\/archneur.62.11.1698","article-title":"Refractory status epilepticus: effect of treatment aggressiveness on prognosis","volume":"62","author":"Rossetti","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib19","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1212\/WNL.51.6.1765","article-title":"Refractory status epilepticus: response to ketamine","volume":"51","author":"Sheth","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib20","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0920-1211(90)90065-4","article-title":"A progressive sequence of electroencephalographic changes during generalized convulsive status epilepticus","volume":"5","author":"Treiman","year":"1990","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib21","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1093\/brain\/awl097","article-title":"The spectrum of clinical disease caused by the A467T and W748S POLG mutations: a study of 26 cases","volume":"129","author":"Tzoulis","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S1525-5050(02)00643-1","article-title":"Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity","volume":"4","author":"Ubogu","year":"2003","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2008.08.005_bib23","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1007\/s00134-003-1905-x","article-title":"The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome","volume":"29","author":"Vasile","year":"2003","journal-title":"Intensive Care Med."},{"issue":"Suppl. 1","key":"10.1016\/j.eplepsyres.2008.08.005_bib24","first-page":"16","article-title":"NMDA receptor trafficking during the transition from single seizures to status epilepticus","volume":"52","author":"Wasterlain","year":"2002","journal-title":"Ann. Neurol."}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092012110800226X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092012110800226X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:20:27Z","timestamp":1760275227000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092012110800226X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":24,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S092012110800226X"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2008.08.005","relation":{},"ISSN":["0920-1211"],"issn-type":[{"type":"print","value":"0920-1211"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ketamine successfully terminates malignant status epilepticus","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2008.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}