{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T19:42:26Z","timestamp":1773085346469,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,8,1]],"date-time":"2009-08-01T00:00:00Z","timestamp":1249084800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2009,8]]},"DOI":"10.1016\/j.eplepsyres.2009.03.015","type":"journal-article","created":{"date-parts":[[2009,4,27]],"date-time":"2009-04-27T07:00:17Z","timestamp":1240815617000},"page":"187-198","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["Network characteristics of idiopathic generalized epilepsies in combined MEG\/EEG"],"prefix":"10.1016","volume":"85","author":[{"given":"Hermann","family":"Stefan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Paulini-Ruf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00fcdiger","family":"Hopfeng\u00e4rtner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Rampp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2009.03.015_bib1","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/brain\/awh136","article-title":"fMRI activation during spike and wave discharges in idiopathic generalized epilepsy","volume":"127","author":"Aghakhani","year":"2004","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1528-1167.2006.00367.x","article-title":"Amygdala kindling in the WAG\/Rij rat model of absence epilepsy","volume":"47","author":"Aker","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib3","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1016\/j.sigpro.2005.07.004","article-title":"Imaging brain synchrony at high spatial temporal resolution: application to MEG signals during absence seizures","volume":"85","author":"Amor","year":"2005","journal-title":"Signal Process."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1080\/01616412.1985.11739692","article-title":"The insular lobe in primates including humans","volume":"7","author":"Augustine","year":"1985","journal-title":"Neurol. Res."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib5","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1152\/jn.1983.50.4.819","article-title":"An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons","volume":"50","author":"Avoli","year":"1983","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib6","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0013-4694(88)90162-9","article-title":"Morphology of spikes in spike-and-wave complexes","volume":"69","author":"Blume","year":"1988","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib7","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1523\/JNEUROSCI.08-11-04007.1988","article-title":"Nucleus basalis and thalamic control of neocortical activity in the freely moving rat","volume":"8","author":"Buzsaki","year":"1988","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib8","doi-asserted-by":"crossref","unstructured":"Commission on Classification and Terminology of the International League Against Epilepsy, 1981. Proposal for revised clinical and electrographic classification of epileptic seizures. Epilepsia 22, 489\u2013501.","DOI":"10.1111\/j.1528-1157.1981.tb06159.x"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib9","doi-asserted-by":"crossref","first-page":"9099","DOI":"10.1523\/JNEUROSCI.18-21-09099.1998","article-title":"Spike-and-wave oscillations based on the properties of GABAB receptors","volume":"18","author":"Destexhe","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib10","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/j.neuroimage.2006.05.059","article-title":"A GABAA receptor mutation causing generalized epilepsy reduces benzodiazepine receptor binding","volume":"32","author":"Fedi","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib11","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/0013-4694(77)90279-6","article-title":"Spike\u2013wave rhythms in cat cortex induced by parenteral penicillin. I. Electroencephalographic features","volume":"42","author":"Fisher","year":"1977","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib12","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.neuroimage.2006.02.016","article-title":"EEG\u2013fMRI of idiopathic and secondarily generalized epilepsies","volume":"31","author":"Hamandi","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib13","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1111\/j.0013-9580.2004.23204.x","article-title":"Are \u201cgeneralized\u201d seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence","volume":"45","author":"Holmes","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0006-8993(93)91641-5","article-title":"Thalamic multiple-unit activity underlying spike\u2013wave discharges in anesthetized rats","volume":"612","author":"Inoue","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib15","first-page":"272","article-title":"Experimental studies on the functional anatomy of petit mal epilepsy","volume":"26","author":"Jasper","year":"1947","journal-title":"Assoc. Res. Nerv. Ment. Dis."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib16","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/S1388-2457(02)00047-0","article-title":"Systematic source estimation of spikes by a combination of independent component analysis and RAP-MUSIC. II. Preliminary clinical application","volume":"113","author":"Kobayashi","year":"2002","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib17","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/ana.410350319","article-title":"Predictive value of induction of psychogenic seizures by suggestion","volume":"35","author":"Lancman","year":"1994","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib18","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1542\/peds.5.4.626","article-title":"Clinical correlates of the fast and the slow spike\u2013wave electroencephalogram","volume":"5","author":"Lennox","year":"1950","journal-title":"Pediatrics"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib19","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0920-1211(02)00084-0","article-title":"Focal features in patients with idiopathic generalized epilepsy","volume":"50","author":"Leutmezer","year":"2002","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib20","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1111\/j.1528-1167.2008.01724.x","article-title":"EEG\u2013fMRI study of the ictal and interictal epileptic activity in patients with eyelid myoclonia with absences","volume":"49","author":"Liu","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib21","doi-asserted-by":"crossref","first-page":"205","DOI":"10.3949\/ccjm.51.2.205","article-title":"Generalized epilepsies: a review","volume":"51","author":"Luders","year":"1984","journal-title":"Cleve. Clin. Q."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib22","first-page":"129","article-title":"Thalamocortical neurons actively participate in the generation of spike-and-wave seizures in rodents","volume":"24","author":"McCormick","year":"1998","journal-title":"Soc. Neurosci. Abstr."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib23","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0014-4886(84)90151-1","article-title":"Transition from spindles to generalized spike and wave discharges in the cat: simultaneous single-cell recordings in cortex and thalamus","volume":"85","author":"McLachlan","year":"1984","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib24","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1523\/JNEUROSCI.22-04-01480.2002","article-title":"Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats","volume":"22","author":"Meeren","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib25","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1001\/archneur.62.6.946","article-title":"Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy","volume":"62","author":"Meschaks","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib26","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1016\/j.neuroimage.2007.10.058","article-title":"Changes in activity of striato-thalamo-cortical network precede generalized spike wave discharges","volume":"39","author":"Moeller","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib27","unstructured":"Niedermeyer, E., 2000. Epileptic seizure disorders. In: Niedermeyer, E., Lopez da Silva, S.H. (Eds.), Electroencephalography: Basic Principles, Clinical Applications and Related Fields. Urban und Schwarzenberg, Baltimore, pp. 476\u2013585."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib28","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.clinph.2003.10.036","article-title":"Automated interictal spike detection and source localization in magnetoencephalography using independent components analysis and spatio-temporal clustering","volume":"115","author":"Ossadtchi","year":"2004","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib29","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/brain\/98.3.427","article-title":"Simultaneous recording of absence seizures with video tape and electroencephalography. A study of 374 seizures in 48 patients","volume":"98","author":"Penry","year":"1975","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib30","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/0013-4694(64)90163-4","article-title":"Intracellular studies of cortical neurons during thalamic induced wave and spike","volume":"17","author":"Pollen","year":"1964","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib31","unstructured":"Poupart, 1707. The Falling Sickness. Hopkins, Baltimore."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib32","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/cne.902440208","article-title":"Projections of thalamic gustatory and lingual areas in the monkey, Macaca fascicularis","volume":"244","author":"Pritchard","year":"1986","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib33","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A default mode of brain function","volume":"98","author":"Raichle","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib34","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF01186769","article-title":"Source analysis of generalized spike\u2013wave complexes","volume":"7","author":"Rodin","year":"1994","journal-title":"Brain Topogr."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib35","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/ana.10586","article-title":"Functional magnetic resonance imaging of human absence seizures","volume":"53","author":"Salek-Haddadi","year":"2003","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib36","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1528-1157.2000.tb00158.x","article-title":"MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy","volume":"41","author":"Savic","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib37","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1046\/j.1460-9568.1998.00123.x","article-title":"Relations between cortical and thalamic cellular activities during absence seizures in rats","volume":"10","author":"Seidenbecher","year":"1998","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0387-7604(93)90043-8","article-title":"Simultaneous EEG-VTR and transverse topographical analysis of absence seizures in children","volume":"15","author":"Shylaja","year":"1993","journal-title":"Brain Dev."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib39","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1523\/JNEUROSCI.21-04-01378.2001","article-title":"Contribution of GABA(A) and GABA(B) receptors to thalamic neuronal activity during spontaneous absence seizures in rats","volume":"21","author":"Staak","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib40","unstructured":"Stefan, H., 1982. Studien zur Anfallsstruktur, Pathophysiologie und zum klinischen Verlauf. Habilitationsschrift, Bonn."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib41","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0013-4694(74)90028-5","article-title":"Interneuronal epileptic discharges related to spike-and-wave cortical seizures in behaving monkeys","volume":"37","author":"Steriade","year":"1974","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib42","unstructured":"Tissot, S.A., 1770. Trait\u00e9 de l\u2018\u00e9pilepsie, T.3. Du trait\u00e9 des nerfs et de leurs maladies. Paris."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib43","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.neubiorev.2006.03.002","article-title":"Global and focal aspects of absence epilepsy: the contribution of genetic models","volume":"30","author":"van Luijtelaar","year":"2006","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.eplepsyres.2009.03.015_bib44","doi-asserted-by":"crossref","unstructured":"Zumsteg, D., Wennberg, R.A., 2005. Interhemispheric preponderance of noninvasive source algorithms: commentary on two recently published articles. Epilepsia 46, 1337\u20131339; author reply 1339\u20131340.","DOI":"10.1111\/j.1528-1167.2005.18505_8.x"}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121109000771?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121109000771?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:21:34Z","timestamp":1760275294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121109000771"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,8]]},"references-count":44,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2009,8]]}},"alternative-id":["S0920121109000771"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2009.03.015","relation":{},"ISSN":["0920-1211"],"issn-type":[{"value":"0920-1211","type":"print"}],"subject":[],"published":{"date-parts":[[2009,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Network characteristics of idiopathic generalized epilepsies in combined MEG\/EEG","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2009.03.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}