{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:40:07Z","timestamp":1760276407285,"version":"build-2065373602"},"reference-count":19,"publisher":"Elsevier BV","issue":"2-3","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.eplepsyres.2010.11.006","type":"journal-article","created":{"date-parts":[[2010,12,17]],"date-time":"2010-12-17T04:16:37Z","timestamp":1292559397000},"page":"192-196","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Valproate decreases frequency facilitation at mossy fiber\u2014CA3 synapses after status epilepticus"],"prefix":"10.1016","volume":"93","author":[{"given":"Pishan","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew C.","family":"Walker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0005","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.ejcb.2006.04.013","article-title":"The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum","volume":"85","author":"Boeckeler","year":"2006","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0010","doi-asserted-by":"crossref","first-page":"11382","DOI":"10.1523\/JNEUROSCI.23-36-11382.2003","article-title":"Plasticity of GABAB receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus","volume":"23","author":"Chandler","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0015","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1111\/j.1528-1167.2009.02412.x","article-title":"Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP","volume":"51","author":"Chang","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0020","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0301-0082(82)90010-7","article-title":"Mechanism of anticonvulsant action of valproate","volume":"19","author":"Chapman","year":"1982","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0025","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jneumeth.2008.04.019","article-title":"The pilocarpine model of temporal lobe epilepsy","volume":"172","author":"Curia","year":"2008","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0030","doi-asserted-by":"crossref","first-page":"3434","DOI":"10.1523\/JNEUROSCI.20-09-03434.2000","article-title":"Metaplasticity of mossy fiber synaptic transmission involves altered release probability","volume":"20","author":"Goussakov","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0035","doi-asserted-by":"crossref","first-page":"21S","DOI":"10.1212\/WNL.59.9_suppl_5.S21","article-title":"Epilepsy after brain insult: targeting epileptogenesis","volume":"59","author":"Herman","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0040","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1528-1157.1995.tb01613.x","article-title":"Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs","volume":"36","author":"H\u00f6nack","year":"1995","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0045","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0014-2999(98)00410-5","article-title":"Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy","volume":"353","author":"Klitgaard","year":"1998","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0050","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2165\/00023210-200216100-00003","article-title":"Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy","volume":"16","author":"L\u00f6scher","year":"2002","journal-title":"CNS Drugs"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0055","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1016\/S0022-3565(25)24725-5","article-title":"The novel competitive N-methyl-d-aspartate (NMDA) antagonist CGP 37849 preferentially induces phencyclidine-like behavioral effects in kindled rats: attenuation by manipulation of dopamine, alpha-1 and serotonin1A receptors","volume":"257","author":"L\u00f6cher","year":"1991","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0060","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/S0022-3565(25)22759-8","article-title":"Valproic acid in amygdala-kindled rats: alterations in anticonvulsant efficacy, adverse effects and drug and metabolite levels in various brain regions during chronic treatment","volume":"250","author":"L\u00f6scher","year":"1989","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0065","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/S0022-3565(25)24966-7","article-title":"Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture","volume":"237","author":"McLean","year":"1986","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0070","doi-asserted-by":"crossref","first-page":"13304","DOI":"10.1073\/pnas.93.23.13304","article-title":"Distinct short-term plasticity at two excitatory synapses in the hippocampus","volume":"93","author":"Salin","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0075","doi-asserted-by":"crossref","first-page":"7071","DOI":"10.1523\/JNEUROSCI.0946-06.2006","article-title":"Main determinants of presynaptic Ca2+ dynamics at individual mossy fiber-CA3 pyramidal cell synapses","volume":"26","author":"Scott","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0080","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0920-1211(93)90031-2","article-title":"The excitatory amino acid antagonist d-CPP-ene (SDZ EAA-494) in patients with epilepsy","volume":"16","author":"Sveinbjornsdottir","year":"1993","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0085","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1002\/hipo.1055","article-title":"Revisiting the role of the hippocampal mossy fiber synapse","volume":"11","author":"Urban","year":"2001","journal-title":"Hippocampus"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0090","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1093\/brain\/awf203","article-title":"Disease modification in partial epilepsy","volume":"125","author":"Walker","year":"2002","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2010.11.006_bib0095","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1146\/annurev.physiol.64.092501.114547","article-title":"Short-term synaptic plasticity","volume":"64","author":"Zucker","year":"2002","journal-title":"Annu. Rev. Physiol."}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121110003311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121110003311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:24:38Z","timestamp":1760275478000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121110003311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":19,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0920121110003311"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2010.11.006","relation":{},"ISSN":["0920-1211"],"issn-type":[{"type":"print","value":"0920-1211"}],"subject":[],"published":{"date-parts":[[2011,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Valproate decreases frequency facilitation at mossy fiber\u2014CA3 synapses after status epilepticus","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2010.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}