{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:28:10Z","timestamp":1778635690443,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.eplepsyres.2016.11.008","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T17:01:13Z","timestamp":1479488473000},"page":"74-78","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Generalized epilepsy syndromes and callosal thickness: Differential effects between patients with juvenile myoclonic epilepsy and those with generalized tonic-clonic seizures alone"],"prefix":"10.1016","volume":"129","author":[{"given":"Stavroula","family":"Anastasopoulou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Kurth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen","family":"Luders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivanka","family":"Savic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0005","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0006-8993(92)90178-C","article-title":"Fiber composition of the human corpus callosum","volume":"598","author":"Aboitiz","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0010","doi-asserted-by":"crossref","first-page":"e138","DOI":"10.1111\/epi.12330","article-title":"Regional increase of cerebral cortex thickness in juvenile myoclonic epilepsy","volume":"54","author":"Alhusaini","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0015","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/nbm.782","article-title":"The basis of anisotropic water diffusion in the nervous system \u2212 a technical review","volume":"15","author":"Beaulieu","year":"2002","journal-title":"NMR Biomed."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0020","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1528-1167.2010.02522.x","article-title":"Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005\u20132009","volume":"51","author":"Berg","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0025","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1212\/01.wnl.0000230171.23913.cf","article-title":"Structural changes in patients with primary generalized tonic and clonic seizures","volume":"67","author":"Ciumas","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0030","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.neuroimage.2010.02.051","article-title":"The dopamine system in idiopathic generalized epilepsies: identification of syndrome-related changes","volume":"51","author":"Ciumas","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0035","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.yebeh.2016.07.015","article-title":"The relationship between white matter abnormalities and cognitive functions in new-onset juvenile myoclonic epilepsy","volume":"62","author":"Ekmekci","year":"2016","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0040","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.1002\/hbm.22405","article-title":"Idiopathic-generalized epilepsy shows profound white matter diffusion-tensor imaging alterations","volume":"35","author":"Focke","year":"2014","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0045","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/jnnp.2005.074682","article-title":"Increased thalamus levels of glutamate and glutamine (Glx) in patients with idiopathic generalised epilepsy","volume":"77","author":"Helms","year":"2006","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0050","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.neuroimage.2006.05.044","article-title":"Topography of the human corpus callosum revisited\u2013comprehensive fiber tractography using diffusion tensor magnetic resonance imaging","volume":"32","author":"Hofer","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0055","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.neuroimage.2009.08.004","article-title":"Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks","volume":"49","author":"Holmes","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0060","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1148\/radiol.13131638","article-title":"Generalized tonic-clonic seizures: aberrant interhemispheric functional and anatomical connectivity","volume":"271","author":"Ji","year":"2014","journal-title":"Radiology"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0065","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/j.1528-1167.2012.03544.x","article-title":"Microstructural white matter abnormality and frontal cognitive dysfunctions in juvenile myoclonic epilepsy","volume":"53","author":"Kim","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0070","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.seizure.2015.06.009","article-title":"Extrafrontal structural changes in juvenile myoclonic epilepsy: a topographic analysis of combined structural and microstructural brain imaging","volume":"30","author":"Kim","year":"2015","journal-title":"Seizure"},{"issue":"Suppl. 1","key":"10.1016\/j.eplepsyres.2016.11.008_bib0075","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1016\/j.yebeh.2012.06.035","article-title":"Juvenile myoclonic epilepsy?neuroimaging findings","volume":"28","author":"Koepp","year":"2013","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0080","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1002\/hbm.22060","article-title":"The right inhibition? callosal correlates of hand performance in healthy children and adolescents callosal correlates of hand performance","volume":"34","author":"Kurth","year":"2013","journal-title":"Hum. Brain Mapp."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0085","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.eplepsyres.2009.05.016","article-title":"Voxel-based morphometry evaluation of patients with photosensitive juvenile myoclonic epilepsy","volume":"86","author":"Lin","year":"2009","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0090","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.yebeh.2013.06.034","article-title":"Hippocampal atrophy and memory dysfunction in patients with juvenile myoclonic epilepsy","volume":"29","author":"Lin","year":"2013","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0095","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1111\/j.1528-1167.2011.03313.x","article-title":"Distinct white matter abnormalities in different idiopathic generalized epilepsy syndromes","volume":"52","author":"Liu","year":"2011","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0100","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/WNR.0b013e3280115942","article-title":"Callosal morphology in Williams syndrome: a new evaluation of shape and thickness","volume":"18","author":"Luders","year":"2007","journal-title":"Neuroreport"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0105","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.biopsych.2008.08.027","article-title":"Decreased callosal thickness in attention-deficit\/hyperactivity disorder","volume":"65","author":"Luders","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0110","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.neuroimage.2013.09.040","article-title":"Why size matters: differences in brain volume account for apparent sex differences in callosal anatomy: the sexual dimorphism of the corpus callosum","volume":"84","author":"Luders","year":"2014","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0115","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1001\/archneur.62.6.946","article-title":"Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy","volume":"62","author":"Meschaks","year":"2005","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0120","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1212\/WNL.0b013e318203e93d","article-title":"Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy","volume":"76","author":"O'muircheartaigh","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0125","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.yebeh.2006.11.012","article-title":"Neuropsychological profile of patients with juvenile myoclonic epilepsy: a controlled study of 50 patients","volume":"10","author":"Pascalicchio","year":"2007","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0130","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1528-1167.2007.01482.x","article-title":"Frontal cognitive dysfunction in juvenile myoclonic epilepsy","volume":"49","author":"Piazzini","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0135","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.jns.2010.12.022","article-title":"Hippocampal metabolic dysfunction in juvenile myoclonic epilepsy: 3D multivoxel spectroscopy study","volume":"305","author":"Ristic","year":"2011","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0140","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1528-1167.2012.03413.x","article-title":"Widespread cortical morphologic changes in juvenile myoclonic epilepsy: evidence from structural MRI","volume":"53","author":"Ronan","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0145","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.seizure.2013.01.001","article-title":"Subcortical structural abnormalities in juvenile myoclonic epilepsy (JME): MR volumetry and vertex based analysis","volume":"22","author":"Saini","year":"2013","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0150","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.neuroimage.2003.08.034","article-title":"MRS shows syndrome differentiated metabolite changes in human-generalized epilepsies","volume":"21","author":"Savic","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0155","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1111\/epi.12688","article-title":"Focal abnormalities in idiopathic generalized epilepsy: a critical review of the literature","volume":"55","author":"Seneviratne","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0160","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1212\/WNL.47.5.1203","article-title":"Visual working memory in primary generalized epilepsy: an 18FDG-PET study","volume":"47","author":"Swartz","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0165","doi-asserted-by":"crossref","first-page":"162","DOI":"10.3348\/kjr.2006.7.3.162","article-title":"Structural brain abnormalities in juvenile myoclonic epilepsy patients: volumetry and voxel-based morphometry","volume":"7","author":"Tae","year":"2006","journal-title":"Korean J. Radiol."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0170","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00415-008-0745-6","article-title":"Cortical thickness abnormality in juvenile myoclonic epilepsy","volume":"255","author":"Tae","year":"2008","journal-title":"J. Neurol."},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0175","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1093\/brain\/awr098","article-title":"Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study","volume":"134","author":"Vollmar","year":"2011","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0180","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1528-1167.2010.02770.x","article-title":"Connectivity of the supplementary motor area in juvenile myoclonic epilepsy and frontal lobe epilepsy","volume":"52","author":"Vulliemoz","year":"2011","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0185","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1111\/epi.12003","article-title":"Frontal lobe function and structure in juvenile myoclonic epilepsy: a comprehensive review of neuropsychological and imaging data","volume":"53","author":"Wandschneider","year":"2012","journal-title":"Epilepsia"},{"issue":"Pt 3","key":"10.1016\/j.eplepsyres.2016.11.008_bib0190","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1093\/brain\/112.3.799","article-title":"Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study","volume":"112","author":"Witelson","year":"1989","journal-title":"Brain"},{"issue":"Pt 11","key":"10.1016\/j.eplepsyres.2016.11.008_bib0195","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1093\/brain\/122.11.2101","article-title":"Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI","volume":"122","author":"Woermann","year":"1999","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2016.11.008_bib0200","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1469-7580.2006.00615.x","article-title":"Functional anatomy of interhemispheric cortical connections in the human brain","volume":"209","author":"Zarei","year":"2006","journal-title":"J. Anat."}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121116303217?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121116303217?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:36:21Z","timestamp":1760276181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121116303217"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":40,"alternative-id":["S0920121116303217"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2016.11.008","relation":{},"ISSN":["0920-1211"],"issn-type":[{"value":"0920-1211","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Generalized epilepsy syndromes and callosal thickness: Differential effects between patients with juvenile myoclonic epilepsy and those with generalized tonic-clonic seizures alone","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2016.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}