{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:06:12Z","timestamp":1770743172642,"version":"3.49.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.eplepsyres.2017.05.003","type":"journal-article","created":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T13:16:10Z","timestamp":1494249370000},"page":"26-32","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Prolonged epileptiform EEG runs are associated with persistent seizures in juvenile myoclonic epilepsy"],"prefix":"10.1016","volume":"134","author":[{"given":"Vibeke","family":"Arntsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trond","family":"Sand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marte R.","family":"Syvertsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eylert","family":"Brodtkorb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0005","first-page":"23","article-title":"Acute effects of subclinical epileptiform EEG discharges on cognitive activation","volume":"20","author":"Aldenkamp","year":"2005","journal-title":"Funct. Neurol."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0010","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1528-1157.1994.tb02433.x","article-title":"Focal electroencephalographic abnormalities in juvenile myoclonic epilepsy","volume":"35","author":"Aliberti","year":"1994","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0015","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1053\/seiz.1999.0376","article-title":"Photosensitivity in juvenile myoclonic epilepsy","volume":"9","author":"Appleton","year":"2000","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0020","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1111\/j.1528-1167.2010.02557.x","article-title":"Can changes in cortical excitability distinguish progressive from juvenile myoclonic epilepsy?","volume":"51","author":"Badawy","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0025","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1212\/01.wnl.0000313148.34629.1d","article-title":"Myoclonic seizures subside in the fourth decade in juvenile myoclonic epilepsy","volume":"70","author":"Baykan","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0030","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1111\/epi.12135","article-title":"Standardized computer-based organized reporting of EEG: SCORE","volume":"54","author":"Beniczky","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0035","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1528-1167.2006.00462.x","article-title":"EEG features in idiopathic generalized epilepsy: clues to diagnosis","volume":"47","author":"Betting","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0040","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1212\/WNL.0b013e3181b9c86f","article-title":"Juvenile myoclonic epilepsy 25 years after seizure onset: a population-based study","volume":"73","author":"Camfield","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0045","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.seizure.2007.07.005","article-title":"Valproate decreases EEG synchronization in a use-dependent manner in idiopathic generalized epilepsy","volume":"17","author":"Clemens","year":"2008","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0050","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1528-1157.1989.tb05316.x","article-title":"Commission on classification and terminology of the international league of epilepsy","volume":"30","author":"Commission","year":"1989","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0055","first-page":"230","article-title":"The effect of lamotrigine on epileptiform discharges in young patients with drug-resistant epilepsy","volume":"42","author":"Eriksson","year":"2001","journal-title":"Epilepsia (Series 4)"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0060","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1053\/seiz.2000.0432","article-title":"Characteristics of valproic acid resistant juvenile myoclonic epilepsy","volume":"9","author":"Fernando-Dongas","year":"2000","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0065","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1111\/j.1528-1167.2012.03526.x","article-title":"Predictors for long-term seizure outcome in juvenile myoclonic epilepsy: 25-63 years of follow-up","volume":"53","author":"Geithner","year":"2012","journal-title":"Epilepsia"},{"issue":"Suppl 1","key":"10.1016\/j.eplepsyres.2017.05.003_bib0070","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/j.yebeh.2012.10.034","article-title":"Clinical aspects of juvenile myoclonic epilepsy","volume":"28","author":"Genton","year":"2013","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0075","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1111\/epi.13702","article-title":"Resistance to valproic acid as predictor of treatment resistance in genetic generalized epilepsies","volume":"58","author":"Gesche","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0080","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/j.eplepsyres.2014.09.008","article-title":"Seizure outcome in 175 patients with juvenile myoclonic epilepsy \u2013 a long-term observational study","volume":"108","author":"H\u00f6fler","year":"2014","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0085","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.3949\/ccjm.56.s1.23","article-title":"Juvenile myoclonic epilepsy - epilepsy with impulsive petit mal","volume":"56","author":"Janz","year":"1989","journal-title":"Clevel. Clin. J. Med."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0090","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1016\/j.clinph.2015.11.048","article-title":"Focal EEG features and therapeutic response in patients with juvenile absence and myoclonic epilepsy","volume":"127","author":"Japaridze","year":"2016","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0095","first-page":"115","article-title":"Focal clinical and electroencephalographic features in patients with juvenile myoclonic epilepsy","volume":"122","author":"Jayalakshmi","year":"2010","journal-title":"Acta Neurol. Scand."},{"issue":"Suppl 1","key":"10.1016\/j.eplepsyres.2017.05.003_bib0100","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1016\/j.yebeh.2012.11.051","article-title":"Consensus on diagnosis and management of JME: From founder's observations to current trends","volume":"28","author":"Kasteleijn-Nolst Trenit\u00e9","year":"2013","journal-title":"Epilepsy Behav."},{"issue":"Suppl 1","key":"10.1016\/j.eplepsyres.2017.05.003_bib0105","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/j.yebeh.2012.11.045","article-title":"Chronodependency and provocative factors in juvenile myoclonic epilepsy","volume":"28","author":"Kasteleijn-Nolst Trenite","year":"2013","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0110","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.eplepsyres.2007.07.010","article-title":"Usefulness of a morning routine EEG recording in patients with juvenile myoclonic epilepsy","volume":"77","author":"Labate","year":"2007","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0115","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1528-1157.1994.tb02434.x","article-title":"Clinical and EEG asymmetries in juvenile myoclonic epilepsy","volume":"35","author":"Lancman","year":"1994","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0120","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1017\/S0317167100051519","article-title":"Epileptiform asymetries and treatment response in juvenile myoclonic epilepsy","volume":"37","author":"Letourneau","year":"2010","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0125","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0920-1211(02)00084-0","article-title":"Focal features in patients with idiopathic generalized epilepsy","volume":"50","author":"Leutmezer","year":"2002","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0130","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/j.1528-1157.1997.tb01467.x","article-title":"Consistent EEG focalities detected in subjects with primary generalized epilepsies monitored for two decades","volume":"38","author":"Lombroso","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0135","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1059-1311(95)80090-5","article-title":"Juvenile myoclonic epilepsy and human leukocyte antigens","volume":"4","author":"Moen","year":"1995","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0140","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ana.410250411","article-title":"Absences in juvenile myoclonic epilepsy: a clinical and video-electroencephalographic study","volume":"25","author":"Panayiotopoulos","year":"1989","journal-title":"Ann. Neurol."},{"issue":"Suppl 4","key":"10.1016\/j.eplepsyres.2017.05.003_bib0145","first-page":"S19","article-title":"Juvenile myoclonic epilepsy: long-term response to therapy","volume":"30","author":"Penry","year":"1989","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0150","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1136\/bmj.316.7139.1236","article-title":"What's wrong with Bonferroni adjustments","volume":"316","author":"Perneger","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0155","article-title":"EEG correlates of seizure freedom in genetic generalized epilepsies","author":"Seneviratne","year":"2017","journal-title":"Neurology: Clinical Practice"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0160","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1111\/j.1528-1167.2012.03723.x","article-title":"The prognosis of idiopathic generalized epilepsy","volume":"53","author":"Seneviratne","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0165","first-page":"2128","article-title":"Prognosis of juvenile myoclonic epilepsy 45 years after onset: seizure outcome and predictors","volume":"81","author":"Senf","year":"2013","journal-title":"Neurology"},{"issue":"Suppl. 1","key":"10.1016\/j.eplepsyres.2017.05.003_bib0170","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1016\/j.yebeh.2012.11.042","article-title":"Neurophysiology of juvenile myoclonic epilepsy","volume":"28","author":"Serafini","year":"2013","journal-title":"SerafiniEpilepsy & Behavior"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0175","first-page":"12","article-title":"Clinical and EEG characteristics of Juvenile Myoclonic Epilepsy","volume":"30","author":"Shahnaz","year":"2014","journal-title":"Pak J. Med. Sci."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0180","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.seizure.2007.03.012","article-title":"Frequency, causes and phenomenology of late seizure recurrence in patients with juvenile myoclonic epilepsy after a long period of remission","volume":"16","author":"Sokic","year":"2007","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0185","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/j.1528-1167.2007.01523.x","article-title":"Effects of levetiracetam on EEG abnormalities in juvenile myoclonic epilepsy","volume":"49","author":"Specchio","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0190","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1097\/00007691-199902000-00014","article-title":"Valproate monotherapy in juvenile myoclonic epilepsy: dose-related effects on electroencephalographic and other neurophysiologic tests","volume":"21","author":"Sundqvist","year":"1999","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0195","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/epi.13613","article-title":"Prevalence of juvenile myoclonic epilepsy in people <30 years of age\u2014A population-based study in Norway","volume":"58","author":"Syvertsen","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0200","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.seizure.2014.01.012","article-title":"Clinical heterogeneity of juvenile myoclonic epilepsy: follow-up after an interval of more than 20 years","volume":"23","author":"Syvertsen","year":"2014","journal-title":"Seizure"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0205","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.yebeh.2010.02.005","article-title":"Seizure control in patients with idiopathic generalized epilepsies: EEG determinants of medication response","volume":"17","author":"Szaflarski","year":"2010","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0210","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1111\/j.1528-1167.2005.00262.x","article-title":"Focal semiologic and electroencephalographic features in patients with juvenile myoclonic epilepsy","volume":"46","author":"Usui","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2017.05.003_bib0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.5505\/epilepsi.2012.09719","article-title":"Prognostic role of focal clinical findings and electroencephalographic features of patients with juvenile myoclonic epilepsy","volume":"18","author":"Yasemin Bi\u00e7er","year":"2012","journal-title":"Epilepsi"}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121117301493?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121117301493?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:36:15Z","timestamp":1760276175000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121117301493"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":43,"alternative-id":["S0920121117301493"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2017.05.003","relation":{},"ISSN":["0920-1211"],"issn-type":[{"value":"0920-1211","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prolonged epileptiform EEG runs are associated with persistent seizures in juvenile myoclonic epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2017.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}