{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T03:45:36Z","timestamp":1793763936426,"version":"4.6.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2019,5]]},"DOI":"10.1016\/j.eplepsyres.2019.02.012","type":"journal-article","created":{"date-parts":[[2019,2,25]],"date-time":"2019-02-25T12:04:33Z","timestamp":1551096273000},"page":"52-58","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["Association between ambient air pollution and hospital admission for epilepsy in Eastern China"],"prefix":"10.1016","volume":"152","author":[{"given":"Xiaoyuan","family":"Bao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4948-626X","authenticated-orcid":false,"given":"Xin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghua","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0005","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/1471-2288-14-122","article-title":"Conditional Poisson models: a flexible alternative to conditional logistic case cross-over analysis","volume":"14","author":"Armstrong","year":"2014","journal-title":"BMC Med. Res. Methodol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0010","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1111\/epi.13766","article-title":"Psychiatric and behavioral comorbidities in epilepsy: a critical reappraisal","volume":"58","author":"Berg","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0015","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.acvd.2017.05.003","article-title":"Cardiovascular effects of air pollution","volume":"110","author":"Bourdrel","year":"2017","journal-title":"Arch. Cardiovasc. Dis."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0020","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.envint.2010.03.008","article-title":"Air pollution and hospitalization for epilepsy in Chile","volume":"36","author":"Cakmak","year":"2010","journal-title":"Environ. Int."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0025","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3389\/fnins.2013.00183","volume":"7","author":"Calderon-Garciduenas","year":"2013","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0030","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1111\/cea.12795","article-title":"The effects of air pollution on asthma hospital admissions in Adelaide, South Australia, 2003-2013: time-series and case-crossover analyses","volume":"46","author":"Chen","year":"2016","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0035","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.cardfail.2014.10.001","article-title":"Risk factors for heart failure in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl","volume":"20","author":"Chin","year":"2014","journal-title":"J. Card. Fail."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0040","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3109\/08958378.2016.1145770","article-title":"Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study","volume":"28","author":"Cliff","year":"2016","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0045","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.yebeh.2015.12.038","article-title":"Psychiatric comorbidities in patients from seven families with autosomal dominant cortical tremor, myoclonus, and epilepsy","volume":"56","author":"Coppola","year":"2016","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0050","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/736385","article-title":"Neurotoxicants are in the air: convergence of human, animal, and in vitro studies on the effects of air pollution on the brain","volume":"2014","author":"Costa","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0055","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.neuro.2015.11.008","article-title":"Neurotoxicity of traffic-related air pollution","volume":"59","author":"Costa","year":"2017","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0060","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1743-8977-5-4","article-title":"Exposure to diesel exhaust induces changes in EEG in human volunteers. Part","volume":"5","author":"Cruts","year":"2008","journal-title":"Fibre Toxicol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0065","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph15020176","article-title":"Physical activity, a critical exposure factor of environmental pollution in children and adolescents health risk assessment","volume":"15","author":"Dong","year":"2018","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0070","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1600-0773.1990.tb00722.x","article-title":"Effect of NO2 on lipids and lipid peroxidation in the CNS of the guinea-pig","volume":"66","author":"Farahani","year":"1990","journal-title":"Pharmacol. Toxicol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0075","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1080\/03601239209372767","article-title":"Nitrogen dioxide induced changes in level of free fatty acids, triglyceride, esterified fatty acid, ganglioside and lipase activity in the guinea pig brain","volume":"27","author":"Farahani","year":"1992","journal-title":"J. Environ. Sci. Health B"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0080","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/j.0013-9580.2005.66104.x","article-title":"Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)","volume":"46","author":"Fisher","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0085","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.yebeh.2017.12.032","article-title":"Quality of life in Malaysian children with epilepsy","volume":"80","author":"Fong","year":"2018","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0090","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/s12940-017-0270-0","article-title":"Air pollution, cardiovascular endpoints and susceptibility by stress and material resources: a systematic review of the evidence","volume":"16","author":"Fuller","year":"2017","journal-title":"Environ. Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0095","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.yebeh.2017.08.024","article-title":"Incidence of sudden unexpected death in epilepsy in community-based cohort in China","volume":"76","author":"Ge","year":"2017","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0100","article-title":"Impact of exposure measurement error in air pollution epidemiology: effect of error type in time-series studies","volume":"10","author":"Goldman","year":"2011","journal-title":"Environ. Health-Glob."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0105","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.toxlet.2013.07.012","article-title":"Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum","volume":"222","author":"Guerra","year":"2013","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0110","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1021\/tx500392n","article-title":"Seasonal variation in air particulate matter (PM10) exposure-induced ischemia-like injuries in the rat brain","volume":"28","author":"Guo","year":"2015","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0115","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.yebeh.2018.01.034","article-title":"Quality of life and level of burden in primary caregivers of patients with epilepsy: effect of neuropsychiatric comorbidity","volume":"81","author":"Gutierrez-Angel","year":"2018","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0120","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/978-1-4939-7526-6_13","article-title":"A rat model of perinatal seizures provoked by global hypoxia","volume":"1717","author":"Justice","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0125","doi-asserted-by":"crossref","first-page":"16860","DOI":"10.1007\/s11356-017-9298-5","article-title":"Hospital admissions in Iran for cardiovascular and respiratory diseases attributed to the Middle Eastern Dust storms","volume":"24","author":"Khaniabadi","year":"2017","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0130","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.chemosphere.2016.08.009","article-title":"PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain","volume":"163","author":"Ku","year":"2016","journal-title":"Chemosphere"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0135","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3988\/jcn.2014.10.3.175","article-title":"Depression and anxiety in people with epilepsy","volume":"10","author":"Kwon","year":"2014","journal-title":"J. Clin. Neurol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0140","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.yebeh.2018.01.005","article-title":"Stress, seizures, and epilepsy: patient narratives","volume":"80","author":"Lang","year":"2018","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0145","doi-asserted-by":"crossref","first-page":"3366","DOI":"10.1002\/sim.5420","article-title":"Using spline models to estimate the varying health risks from air pollution across Scotland","volume":"31","author":"Lee","year":"2012","journal-title":"Stat. Med."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0150","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1136\/jech-2014-203892","article-title":"Ambient air pollution in China poses a multifaceted health threat to outdoor physical activity","volume":"69","author":"Li","year":"2015","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0155","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/978-981-10-5657-4_5","article-title":"Air pollution and mortality in China","volume":"1017","author":"Lin","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0160","doi-asserted-by":"crossref","first-page":"2052","DOI":"10.1161\/STROKEAHA.116.016482","article-title":"Ambient particulate matter concentrations and hospitalization for stroke in 26 Chinese cities: a case-crossover study","volume":"48","author":"Liu","year":"2017","journal-title":"Stroke"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0165","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.envint.2017.01.010","article-title":"Influence of exposure to coarse, fine and ultrafine urban particulate matter and their biological constituents on neural biomarkers in a randomized controlled crossover study","volume":"101","author":"Liu","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0170","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.neuro.2011.12.001","article-title":"Neurological impacts from inhalation of pollutants and the nose-brain connection","volume":"33","author":"Lucchini","year":"2012","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0175","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.1038\/s41598-018-19939-1","article-title":"Acute effects of air pollution on respiratory disease mortalities and outpatients in Southeastern China","volume":"8","author":"Mo","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0180","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.scitotenv.2017.08.205","article-title":"Characteristics of air pollution in different zones of Sichuan Basin, China","volume":"612","author":"Ning","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0185","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/978-981-10-5657-4_10","article-title":"Air pollution, disease burden, and health economic loss in China","volume":"1017","author":"Niu","year":"2017","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0190","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fendo.2017.00369","article-title":"The pollutant organotins leads to respiratory disease by inflammation: a mini-review","volume":"8","author":"Nunes-Silva","year":"2017","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0195","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12940-017-0348-8","article-title":"The association between daily concentrations of air pollution and visits to a psychiatric emergency unit: a case-crossover study","volume":"17","author":"Oudin","year":"2018","journal-title":"Environ. Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0200","doi-asserted-by":"crossref","DOI":"10.1007\/s11136-017-1778-z","article-title":"Health-related quality of life in mothers of children with epilepsy: 10 years after diagnosis","author":"Puka","year":"2018","journal-title":"Qual. Life Res."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0205","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.yebeh.2017.07.009","article-title":"Health-related quality of life in adolescents with epilepsy in Montenegro","volume":"76","author":"Radovic","year":"2017","journal-title":"Epilepsy Behav."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0210","doi-asserted-by":"crossref","first-page":"33","DOI":"10.5152\/TurkThoracJ.2017.16016","article-title":"To investigate the effects of air pollution (PM10 and SO2) on the respiratory diseases asthma and chronic obstructive pulmonary disease","volume":"18","author":"Saygin","year":"2017","journal-title":"Turk. Thorac. J. Toraks Derg."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0215","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.jpeds.2016.10.016","article-title":"The health impact of air pollution and outdoor physical activity on children and adolescents in Mainland China","volume":"180","author":"Si","year":"2017","journal-title":"J. Pediatr."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0220","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ncl.2016.06.015","article-title":"The epidemiology of global epilepsy","volume":"34","author":"Singh","year":"2016","journal-title":"Neurol. Clin."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0225","doi-asserted-by":"crossref","DOI":"10.7189\/jogh.07.020706","article-title":"Prevalence of epilepsy in China between 1990 and 2015: a systematic review and meta-analysis","volume":"7","author":"Song","year":"2017","journal-title":"J. Glob. Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0230","first-page":"389","article-title":"The impact of air pollution to central nervous system in children and adults","volume":"38","author":"Sram","year":"2017","journal-title":"Neuro Endocrinol. Lett."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0235","doi-asserted-by":"crossref","DOI":"10.1136\/archdischild-2017-314543","article-title":"Air pollution and asthma","author":"Vardoulakis","year":"2018","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0240","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1177\/1971400916689342","article-title":"Advanced neuroimaging of carbon monoxide poisoning","volume":"30","author":"Varrassi","year":"2017","journal-title":"Neuroradiol. J."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0245","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.ijcard.2017.06.037","article-title":"Short-term air pollution exposure and cardiovascular events: a 10-year study in the urban area of Como, Italy","volume":"248","author":"Vidale","year":"2017","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0250","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1289\/ehp.0800023","article-title":"Association of traffic-related air pollution with children\u2019s neurobehavioral functions in Quanzhou, China","volume":"117","author":"Wang","year":"2009","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0255","article-title":"The novel relationship between urban air pollution and epilepsy: a time series study","volume":"11","author":"Xu","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0260","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3389\/fpubh.2016.00157","article-title":"A review of epidemiological research on adverse neurological effects of exposure to ambient air pollution","volume":"4","author":"Xu","year":"2016","journal-title":"Front. Public Health"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0265","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.envres.2014.11.012","article-title":"Chronic SO2 inhalation above environmental standard impairs neuronal behavior and represses glutamate receptor gene expression and memory-related kinase activation via neuroinflammation in rats","volume":"137","author":"Yao","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0270","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s12966-017-0592-x","article-title":"The association between ambient fine particulate air pollution and physical activity: a cohort study of university students living in Beijing","volume":"14","author":"Yu","year":"2017","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0275","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.1016\/j.chemosphere.2013.08.063","article-title":"SO(2) inhalation causes synaptic injury in rat hippocampus via its derivatives in vivo","volume":"93","author":"Yun","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0280","doi-asserted-by":"crossref","first-page":"11209","DOI":"10.1038\/s41598-017-11338-2","article-title":"Ambient air pollution, smog episodes and mortality in Jinan, China","volume":"7","author":"Zhang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.eplepsyres.2019.02.012_bib0285","article-title":"Particulate and gaseous pollutants in a petrochemical industrialized valley city, Western China during 2013-2016","author":"Zhou","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121118302912?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121118302912?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:41:34Z","timestamp":1760276494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121118302912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5]]},"references-count":57,"alternative-id":["S0920121118302912"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2019.02.012","relation":{},"ISSN":["0920-1211"],"issn-type":[{"value":"0920-1211","type":"print"}],"subject":[],"published":{"date-parts":[[2019,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between ambient air pollution and hospital admission for epilepsy in Eastern China","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2019.02.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}