{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:17:36Z","timestamp":1791339456924,"version":"4.3.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000065","name":"NINDS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy Research"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1016\/j.eplepsyres.2021.106571","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T07:04:44Z","timestamp":1612595084000},"page":"106571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["Patterns of seizure spread in temporal lobe epilepsy are associated with distinct white matter tracts"],"prefix":"10.1016","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4212-4146","authenticated-orcid":false,"given":"Ezequiel","family":"Gleichgerrcht","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-3667","authenticated-orcid":false,"given":"Adam S.","family":"Greenblatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja S.","family":"Kellermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6414-931X","authenticated-orcid":false,"given":"Nathan","family":"Rowland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6099-3118","authenticated-orcid":false,"given":"W. Alexander","family":"Vandergrift","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn A.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Bonilha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.eplepsyres.2021.106571_bib0005","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1001\/jamaneurol.2018.4316","article-title":"Association of seizure spread with surgical failure in epilepsy","volume":"76","author":"Andrews","year":"2019","journal-title":"JAMA Neurol."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0010","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1093\/brain\/awm108","article-title":"Ictal clinical and scalp-EEG findings differentiating temporal lobe epilepsies from temporal\u2019 plus\u2019 epilepsies","volume":"130","author":"Barba","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0015","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1093\/brain\/awv372","article-title":"Temporal plus epilepsy is a major determinant of temporal lobe surgery failures","volume":"139","author":"Barba","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0020","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1111\/epi.13791","article-title":"Defining epileptogenic networks: contribution of SEEG and signal analysis","volume":"58","author":"Bartolomei","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0025","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1111\/j.1528-1167.2009.02056.x","article-title":"Single-pulse electrical stimulation helps to identify epileptogenic cortex in children","volume":"50","author":"Flanagan","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0030","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1080\/23808993.2017.1364133","article-title":"Structural brain network architecture and personalized medicine in epilepsy","volume":"2","author":"Gleichgerrcht","year":"2017","journal-title":"Expert Rev. Precis. Med. Drug Dev."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0035","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1111\/epi.14528","article-title":"Deep learning applied to whole-brain connectome to determine seizure control after epilepsy surgery","volume":"59","author":"Gleichgerrcht","year":"2018","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0040","article-title":"White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA Epilepsy study","volume":"2019","author":"Hatton","year":"2019","journal-title":"bioRxiv"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0045","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1111\/epi.16318","article-title":"Operative posterior disconnection in epilepsy surgery: experience with 29 patients","volume":"60","author":"Kalbhenn","year":"2019","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0050","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1056\/NEJM200002033420503","article-title":"Early identification of refractory epilepsy","volume":"342","author":"Kwan","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0055","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.eplepsyres.2015.04.009","article-title":"Cortico-cortical evoked potentials for sites of early versus late seizure spread in stereoelectroencephalography","volume":"115","author":"Lega","year":"2015","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0060","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1046\/j.1535-7597.2003.03509.x","article-title":"Long-term outcomes of temporal lobe epilepsy surgery","volume":"3","author":"Marks","year":"2003","journal-title":"Epilepsy Curr."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0065","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.nicl.2017.12.020","article-title":"Structural and effective connectivity in focal epilepsy","volume":"17","author":"Parker","year":"2018","journal-title":"Neuroimage Clin."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0070","first-page":"1","article-title":"Magnetic resonance-guided focused ultrasound for ablation of mesial temporal epilepsy circuits: modeling and theoretical feasibility of a novel noninvasive approach","author":"Parker","year":"2019","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0075","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1111\/epi.13709","article-title":"ILAE classification of the epilepsies: position paper of the ILAE commission for classification and terminology","volume":"58","author":"Scheffer","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0080","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1212\/WNL.51.5.1256","article-title":"Is the underlying cause of epilepsy a major prognostic factor for recurrence?","volume":"51","author":"Semah","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0085","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3389\/fncir.2017.00015","article-title":"Novel neuromodulation techniques to assess interhemispheric communication in neural injury and neurodegenerative diseases","volume":"11","author":"Shin","year":"2017","journal-title":"Front. Neural Circuits"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.116763","article-title":"Dynamic tractography: integrating cortico-cortical evoked potentials and diffusion imaging","volume":"215","author":"Silverstein","year":"2020","journal-title":"NeuroImage"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0095","first-page":"3","article-title":"Definition of intractable epilepsy","volume":"16","author":"Sinha","year":"2011","journal-title":"Neurosciences Riyadh (Riyadh)"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0100","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/S1474-4422(05)70200-3","article-title":"Single pulse electrical stimulation for identification of structural abnormalities and prediction of seizure outcome after epilepsy surgery: a prospective study","volume":"4","author":"Valentin","year":"2005","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0105","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.eplepsyres.2014.10.023","article-title":"The role of the corpus callosum in seizure spread: MRI lesion mapping in oligodendrogliomas","volume":"109","author":"Wieshmann","year":"2015","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0110","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1109\/TMI.2010.2045126","article-title":"Generalized q-sampling imaging","volume":"29","author":"Yeh","year":"2010","journal-title":"IEEE Trans. Med. Imaging"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0115","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/j.neuroimage.2010.11.087","article-title":"Estimation of fiber orientation and spin density distribution by diffusion deconvolution","volume":"55","author":"Yeh","year":"2011","journal-title":"NeuroImage"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0080713","article-title":"Deterministic diffusion fiber tracking improved by quantitative anisotropy","volume":"8","author":"Yeh","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0125","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.neuroimage.2015.10.053","article-title":"Connectometry: a statistical approach harnessing the analytical potential of the local connectome","volume":"125","author":"Yeh","year":"2016","journal-title":"NeuroImage"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0130","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s13311-018-0663-y","article-title":"Automatic removal of false connections in diffusion MRI tractography using topology-informed pruning (TIP)","volume":"16","author":"Yeh","year":"2019","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.eplepsyres.2021.106571_bib0135","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/epi.12505","article-title":"Ictal spread of medial temporal lobe seizures with and without secondary generalization: an intracranial electroencephalography analysis","volume":"55","author":"Yoo","year":"2014","journal-title":"Epilepsia"}],"container-title":["Epilepsy Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121121000243?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0920121121000243?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:44:16Z","timestamp":1760276656000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0920121121000243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":27,"alternative-id":["S0920121121000243"],"URL":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2021.106571","relation":{},"ISSN":["0920-1211"],"issn-type":[{"value":"0920-1211","type":"print"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patterns of seizure spread in temporal lobe epilepsy are associated with distinct white matter tracts","name":"articletitle","label":"Article Title"},{"value":"Epilepsy Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eplepsyres.2021.106571","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106571"}}