{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T22:45:09Z","timestamp":1781649909859,"version":"3.54.5"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100010994","name":"Indian Society of Nephrology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010994","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270408"],"award-info":[{"award-number":["81270408"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570666"],"award-info":[{"award-number":["81570666"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.eprac.2021.02.007","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T09:48:55Z","timestamp":1613900935000},"page":"148-158","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Parathyroidectomy Is Associated With Reversed Nondipping Heart Rate That Impacts Mortality in Chronic Kidney Disease Patients"],"prefix":"10.1016","volume":"28","author":[{"given":"Ying","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkai","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6689-7768","authenticated-orcid":false,"given":"Ying","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Zha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanhui","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaowen","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaoyu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangyan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyang","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1220-6797","authenticated-orcid":false,"given":"Wenbin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0300-7211","authenticated-orcid":false,"given":"Chun","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changying","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongyue","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1363-3101","authenticated-orcid":false,"given":"Ningning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.eprac.2021.02.007_bib1","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.kint.2019.07.012","article-title":"A\u00a0single number for advocacy and communication-worldwide more than 850 million individuals have kidney diseases","volume":"96","author":"Jager","year":"2019","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.eprac.2021.02.007_bib2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1159\/000500053","article-title":"Executive Summary: Clinical Practice Guideline of Chronic Kidney Disease - Mineral and Bone Disorder (CKD-MBD) in China","volume":"5","author":"Liu","year":"2019","journal-title":"Kidney Dis (Basel)"},{"issue":"5","key":"10.1016\/j.eprac.2021.02.007_bib3","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.kint.2017.12.013","article-title":"A\u00a0population-based cohort study defines prognoses in severe chronic kidney disease","volume":"93","author":"Tonelli","year":"2018","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.eprac.2021.02.007_bib4","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/1744-9987.12772","article-title":"Secondary hyperparathyroidism: pathogenesis and latest treatment","volume":"23","author":"Mizobuchi","year":"2019","journal-title":"Ther Apher Dial"},{"issue":"5","key":"10.1016\/j.eprac.2021.02.007_bib5","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0216656","article-title":"Associations of plasma fibroblast growth factor 23 and other markers of chronic kidney disease-mineral and bone disorder with all-cause mortality in South African patients on maintenance dialysis: a 3-year prospective cohort study","volume":"14","author":"Waziri","year":"2019","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.eprac.2021.02.007_bib6","doi-asserted-by":"crossref","first-page":"952","DOI":"10.2215\/CJN.10390917","article-title":"Parathyroidectomy in the management of secondary hyperparathyroidism","volume":"13","author":"Lau","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.eprac.2021.02.007_bib7","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.hrthm.2018.08.026","article-title":"Circadian rhythm of cardiac electrophysiology, arrhythmogenesis, and the underlying mechanisms","volume":"16","author":"D\u2019Black","year":"2019","journal-title":"Heart Rhythm"},{"key":"10.1016\/j.eprac.2021.02.007_bib8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1742-4682-10-7","article-title":"Age and gender dependent heart rate circadian model development and performance verification on the proarrhythmic drug case study","volume":"10","author":"Fijorek","year":"2013","journal-title":"Theor Biol Med Model"},{"key":"10.1016\/j.eprac.2021.02.007_bib9","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.autneu.2018.02.001","article-title":"Nondipping heart rate: a neglected cardiovascular risk factor based on autonomic imbalance?","volume":"210","author":"Baka","year":"2018","journal-title":"Auton Neurosci"},{"issue":"9","key":"10.1016\/j.eprac.2021.02.007_bib10","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1007\/s10157-019-01746-1","article-title":"Increased heart rate is associated with intrarenal renin-angiotensin system activation in chronic kidney disease patients","volume":"23","author":"Ohashi","year":"2019","journal-title":"Clin Exp Nephrol"},{"issue":"8","key":"10.1016\/j.eprac.2021.02.007_bib11","doi-asserted-by":"crossref","first-page":"2482","DOI":"10.1093\/ndt\/gfp057","article-title":"Associations of resting heart rate with insulin resistance, cardiovascular events and mortality in chronic kidney disease","volume":"24","author":"Beddhu","year":"2009","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1016\/j.eprac.2021.02.007_bib12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1053\/j.ajkd.2007.09.019","article-title":"Circadian variation of death in hemodialysis patients","volume":"51","author":"Tisl\u00e9r","year":"2008","journal-title":"Am J Kidney Dis"},{"issue":"19","key":"10.1016\/j.eprac.2021.02.007_bib13","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1001\/archinte.167.19.2116","article-title":"Blunted heart rate dip during sleep and all-cause mortality","volume":"167","author":"Ben-Dov","year":"2007","journal-title":"Arch Intern Med"},{"issue":"2","key":"10.1016\/j.eprac.2021.02.007_bib14","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1161\/HYPERTENSIONAHA.108.113191","article-title":"Prognostic value of ambulatory heart rate revisited in 6928 subjects from 6 populations","volume":"52","author":"Hansen","year":"2008","journal-title":"Hypertension"},{"issue":"11","key":"10.1016\/j.eprac.2021.02.007_bib15","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1097\/HJH.0b013e328330a938","article-title":"Nocturnal nondipping of heart rate predicts cardiovascular events in hypertensive patients","volume":"27","author":"Eguchi","year":"2009","journal-title":"J\u00a0Hypertens"},{"issue":"1","key":"10.1016\/j.eprac.2021.02.007_bib16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ahj.2014.04.012","article-title":"Nocturnal patterns of heart rate and the risk of mortality after acute myocardial infarction","volume":"168","author":"Carney","year":"2014","journal-title":"Am Heart J"},{"issue":"1","key":"10.1016\/j.eprac.2021.02.007_bib17","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000363283","article-title":"Non-dipping heart rate, microalbuminuria and thrombocytosis in type 2 diabetes mellitus: can we connect the dots?","volume":"129","author":"Kantharia","year":"2014","journal-title":"Cardiology"},{"issue":"8","key":"10.1016\/j.eprac.2021.02.007_bib18","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.2215\/CJN.10381012","article-title":"Parathyroidectomy and heart rate variability in patients with stage 5 CKD","volume":"8","author":"Zhang","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"issue":"12","key":"10.1016\/j.eprac.2021.02.007_bib19","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1007\/s11255-018-1995-6","article-title":"Effects of parathyroidectomy on blood bone markers and heart rate variability in patients with stage 5 chronic kidney disease","volume":"50","author":"Chen","year":"2018","journal-title":"Int Urol Nephrol"},{"issue":"10","key":"10.1016\/j.eprac.2021.02.007_bib20","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1055\/a-0723-2807","article-title":"Effects of parathyroidectomy on plasma iPTH and (1-84) PTH levels in patients with stage 5 chronic kidney disease","volume":"50","author":"Huimin","year":"2018","journal-title":"Horm Metab Res"},{"issue":"6","key":"10.1016\/j.eprac.2021.02.007_bib21","doi-asserted-by":"crossref","first-page":"422","DOI":"10.7326\/M17-2640","article-title":"Diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder: synopsis of the Kidney Disease: Improving Global Outcomes 2017 Clinical Practice Guideline update","volume":"168","author":"Ketteler","year":"2018","journal-title":"Ann Intern Med"},{"issue":"12","key":"10.1016\/j.eprac.2021.02.007_bib22","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1161\/STROKEAHA.111.628586","article-title":"Effects of 24-hour blood pressure and heart rate recorded with ambulatory blood pressure monitoring on recovery from acute ischemic stroke","volume":"42","author":"Tomii","year":"2011","journal-title":"Stroke"},{"issue":"7","key":"10.1016\/j.eprac.2021.02.007_bib23","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.jash.2015.03.009","article-title":"Ambulatory 24-hour cardiac oxygen consumption and blood pressure-heart rate variability: effects of nebivolol and valsartan alone and in combination","volume":"9","author":"Izzo","year":"2015","journal-title":"J\u00a0Am Soc Hypertens"},{"issue":"2","key":"10.1016\/j.eprac.2021.02.007_bib24","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/jpi.12348","article-title":"Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review","volume":"61","author":"Simko","year":"2016","journal-title":"J\u00a0Pineal Res"},{"issue":"6","key":"10.1016\/j.eprac.2021.02.007_bib25","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1097\/HJH.0000000000001703","article-title":"Night-time heart rate nondipping: clinical and prognostic significance in the general population","volume":"36","author":"Cuspidi","year":"2018","journal-title":"J\u00a0Hypertens"},{"issue":"8","key":"10.1016\/j.eprac.2021.02.007_bib26","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1097\/HJH.0b013e3283041172","article-title":"Predictive value of ambulatory heart rate in the Japanese general population: the Ohasama study","volume":"26","author":"Hozawa","year":"2008","journal-title":"J\u00a0Hypertens"},{"issue":"9","key":"10.1016\/j.eprac.2021.02.007_bib27","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/00004872-199816090-00015","article-title":"Adverse prognostic value of a blunted circadian rhythm of heart rate in essential hypertension","volume":"16","author":"Verdecchia","year":"1998","journal-title":"J\u00a0Hypertens"},{"issue":"37","key":"10.1016\/j.eprac.2021.02.007_bib28","doi-asserted-by":"crossref","first-page":"12446","DOI":"10.1523\/JNEUROSCI.1667-10.2010","article-title":"\ua7b5-adrenoceptor blockers increase cardiac sympathetic innervation by inhibiting autoreceptor suppression of axon growth","volume":"30","author":"Clarke","year":"2010","journal-title":"J\u00a0Neurosci"},{"issue":"6","key":"10.1016\/j.eprac.2021.02.007_bib29","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1536\/ihj.17-561","article-title":"Effect of sympatholytic therapy on circadian cardiac autonomic activity in non-diabetic chronic kidney disease","volume":"59","author":"Makimoto","year":"2018","journal-title":"Int Heart J"},{"issue":"11","key":"10.1016\/j.eprac.2021.02.007_bib30","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1007\/s10157-019-01782-x","article-title":"Nondipping heart rate and associated factors in patients with chronic kidney disease","volume":"23","author":"Biyik","year":"2019","journal-title":"Clin Exp Nephrol"},{"issue":"6","key":"10.1016\/j.eprac.2021.02.007_bib31","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s11914-018-0486-0","article-title":"CKD-MBD: from the pathogenesis to the identification and development of potential novel therapeutic targets","volume":"16","author":"Elias","year":"2018","journal-title":"Curr Osteoporos Rep"},{"issue":"3","key":"10.1016\/j.eprac.2021.02.007_bib32","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.amjsurg.2018.12.026","article-title":"Changes in serum FGF23 and Klotho levels and calcification scores of the abdominal aorta after parathyroidectomy for secondary hyperparathyroidism","volume":"218","author":"Chou","year":"2019","journal-title":"Am J Surg"},{"issue":"2","key":"10.1016\/j.eprac.2021.02.007_bib33","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1148\/radiol.2016160768","article-title":"18F fluorocholine PET\/MR imaging in patients with primary hyperparathyroidism and inconclusive conventional imaging: a prospective pilot study","volume":"284","author":"Kluijfhout","year":"2017","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.eprac.2021.02.007_bib34","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1080\/0886022X.2019.1707097","article-title":"Comparison of microwave ablation treatments in patients with renal secondary and primary hyperparathyroidism","volume":"42","author":"Ma","year":"2020","journal-title":"Ren Fail"},{"key":"10.1016\/j.eprac.2021.02.007_bib35","doi-asserted-by":"crossref","first-page":"26841","DOI":"10.1038\/srep26841","article-title":"Diagnostic accuracy study of intraoperative and perioperative serum intact PTH level for successful parathyroidectomy in 501 secondary hyperparathyroidism patients","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.eprac.2021.02.007_bib36","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1186\/s12882-020-01917-3","article-title":"Persistent secondary hyperparathyroidism caused by parathyromatosis and supernumerary parathyroid glands in a patient on haemodialysis","volume":"21","author":"Yang","year":"2020","journal-title":"BMC Nephrol"},{"issue":"3","key":"10.1016\/j.eprac.2021.02.007_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.22696","article-title":"Parathyroidectomy decreases serum intact parathyroid hormone and calcium levels and prolongs overall survival in elderly hemodialysis patients with severe secondary hyperparathyroidism","volume":"33","author":"Wan","year":"2019","journal-title":"J\u00a0Clin Lab Anal"},{"issue":"10","key":"10.1016\/j.eprac.2021.02.007_bib38","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.2337\/dc16-0748","article-title":"Association between high and very high albuminuria and nighttime blood pressure: influence of diabetes and chronic kidney disease","volume":"39","author":"Ruiz-Hurtado","year":"2016","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.eprac.2021.02.007_bib39","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1681\/ASN.2015030243","article-title":"Masked uncontrolled hypertension in CKD","volume":"27","author":"Agarwal","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X21000501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X21000501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:12:41Z","timestamp":1761516761000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X21000501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["S1530891X21000501"],"URL":"https:\/\/doi.org\/10.1016\/j.eprac.2021.02.007","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Parathyroidectomy Is Associated With Reversed Nondipping Heart Rate That Impacts Mortality in Chronic Kidney Disease Patients","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eprac.2021.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 AACE. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}