{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:13:36Z","timestamp":1777893216064,"version":"3.51.4"},"reference-count":21,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100008235","name":"Peking Union Medical College Hospital","doi-asserted-by":"publisher","award":["2022-PUMCH-C-028"],"award-info":[{"award-number":["2022-PUMCH-C-028"]}],"id":[{"id":"10.13039\/501100008235","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008235","name":"Peking Union Medical College Hospital","doi-asserted-by":"publisher","award":["2022-PUMCH-B-073"],"award-info":[{"award-number":["2022-PUMCH-B-073"]}],"id":[{"id":"10.13039\/501100008235","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470831"],"award-info":[{"award-number":["82470831"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82070822"],"award-info":[{"award-number":["82070822"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.eprac.2025.06.021","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T03:29:38Z","timestamp":1751426978000},"page":"1585-1591","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Simplification of the Oral Sodium Loading Test: 2-Day Method Replacing 3-Day Method"],"prefix":"10.1016","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4100-6854","authenticated-orcid":false,"given":"Zewen","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunying","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Songlin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anli","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.eprac.2025.06.021_bib1","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1016\/j.jacc.2017.01.052","article-title":"Prevalence and clinical manifestations of primary aldosteronism encountered in primary care practice","volume":"69","author":"Monticone","year":"2017","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.eprac.2025.06.021_bib2","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1016\/j.jacc.2006.07.059","article-title":"A prospective study of the prevalence of primary aldosteronism in 1,125 hypertensive patients","volume":"48","author":"Rossi","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.eprac.2025.06.021_bib3","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1055\/s-0029-1246186","article-title":"Confirmatory tests in the diagnosis of primary aldosteronism","volume":"42","author":"Mulatero","year":"2010","journal-title":"Horm Metab Res Horm Stoffwechselforschung Horm Metab"},{"key":"10.1016\/j.eprac.2025.06.021_bib4","doi-asserted-by":"crossref","first-page":"3266","DOI":"10.1210\/jc.2008-0104","article-title":"Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline","volume":"93","author":"Funder","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.eprac.2025.06.021_bib5","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s00268-003-7069-6","article-title":"Diagnosis and management of primary aldosteronism","volume":"27","author":"Wheeler","year":"2003","journal-title":"World J Surg"},{"key":"10.1016\/j.eprac.2025.06.021_bib6","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1210\/jc.2015-4061","article-title":"The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline","volume":"101","author":"Funder","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.eprac.2025.06.021_bib7","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/HJH.0000000000001905","article-title":"Surprisingly low aldosterone levels in peripheral veins following intravenous sedation during adrenal vein sampling: implications for the concept of nonsuppressibility in primary aldosteronism","volume":"37","author":"Kline","year":"2019","journal-title":"J Hypertens"},{"key":"10.1016\/j.eprac.2025.06.021_bib8","first-page":"F871","article-title":"Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance","volume":"262","author":"Vieweg","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.eprac.2025.06.021_bib9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/01.hjh.0000202818.10459.96","article-title":"Dynamic testing with high-dose adrenocorticotrophic hormone does not improve lateralization of aldosterone oversecretion in primary aldosteronism patients","volume":"24","author":"Rossi","year":"2006","journal-title":"J Hypertens"},{"key":"10.1016\/j.eprac.2025.06.021_bib10","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1161\/HYPERTENSIONAHA.114.03127","article-title":"Sensitivity to aldosterone: plasma levels are not the full story","volume":"63","author":"Funder","year":"2014","journal-title":"Hypertens Dallas Tex"},{"key":"10.1016\/j.eprac.2025.06.021_bib11","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1210\/jc.2002-021476","article-title":"Variability in the renin\/aldosterone profile under random and standardized sampling conditions in primary aldosteronism","volume":"88","author":"Tanabe","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.eprac.2025.06.021_bib12","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1055\/s-0034-1374638","article-title":"The role of urinary aldosterone for the diagnosis of primary aldosteronism","volume":"46","author":"Ceral","year":"2014","journal-title":"Horm Metab Res Horm Stoffwechselforschung Horm Metab"},{"key":"10.1016\/j.eprac.2025.06.021_bib13","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jchromb.2018.03.033","article-title":"The utility of ultra-high performance supercritical fluid chromatography-tandem mass spectrometry (UHPSFC-MS\/MS) for clinically relevant steroid analysis","volume":"1085","author":"Storbeck","year":"2018","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.1016\/j.eprac.2025.06.021_bib14","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jchromb.2012.11.013","article-title":"Quantitation of aldosterone in human plasma by ultra high performance liquid chromatography tandem mass spectrometry","volume":"913\u2013914","author":"Hinchliffe","year":"2013","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.1016\/j.eprac.2025.06.021_bib15","doi-asserted-by":"crossref","first-page":"10","DOI":"10.7326\/M20-0065","article-title":"The unrecognized prevalence of primary aldosteronism: a cross-sectional study","volume":"173","author":"Brown","year":"2020","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.eprac.2025.06.021_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.cca.2023.117325","article-title":"Reference intervals for LC-MS\/MS measurements of plasma renin activity, aldosterone, angiotensin II, and 24-h urinary aldosterone in northern Chinese han population","volume":"543","author":"Yin","year":"2023","journal-title":"Clin Chim Acta Int J Clin Chem"},{"key":"10.1016\/j.eprac.2025.06.021_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2023.123941","article-title":"A comprehensive LC-MS\/MS method for the simultaneous measurement of 24 adrenal steroids: from research to clinical practice","volume":"1232","author":"Yu","year":"2024","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.1016\/j.eprac.2025.06.021_bib18","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jchromb.2019.03.012","article-title":"Establishment of a rapid and simple liquid chromatography tandem mass spectrometry method for measuring aldosterone in urine","volume":"1113","author":"Yin","year":"2019","journal-title":"J Chromatogr B Analyt Technol Biomed Life Sci"},{"key":"10.1016\/j.eprac.2025.06.021_bib19","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/0002-9343(83)91022-7","article-title":"The changing clinical spectrum of primary aldosteronism","volume":"74","author":"Bravo","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.eprac.2025.06.021_bib20","doi-asserted-by":"crossref","DOI":"10.1210\/jendso\/bvaa116","article-title":"Oral salt loading test is associated with 24-h blood pressure and organ damage in primary aldosteronism patients","volume":"4","author":"Yoshida","year":"2020","journal-title":"J Endocr Soc"},{"key":"10.1016\/j.eprac.2025.06.021_bib21","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.ajcnut.2023.09.005","article-title":"Estimation of 24-h urinary sodium and potassium excretion among Chinese adults: a cross-sectional study from the China national nutrition survey","volume":"119","author":"Liu","year":"2024","journal-title":"Am J Clin Nutr"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2500936X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2500936X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:51:17Z","timestamp":1777618277000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X2500936X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":21,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1530891X2500936X"],"URL":"https:\/\/doi.org\/10.1016\/j.eprac.2025.06.021","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Simplification of the Oral Sodium Loading Test: 2-Day Method Replacing 3-Day Method","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eprac.2025.06.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 AACE. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}