{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:30:17Z","timestamp":1780569017865,"version":"3.54.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.eprac.2025.08.005","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T15:17:51Z","timestamp":1755098271000},"page":"1346-1349","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["An Updated Review on the Use of Fine Needle Aspiration Biopsy in Pediatric Thyroid Disease"],"prefix":"10.1016","volume":"31","author":[{"given":"Apoorva","family":"Aekka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Zimmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0339-0166","authenticated-orcid":false,"given":"Jami L.","family":"Josefson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.eprac.2025.08.005_bib1","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1097\/00007611-198912000-00005","article-title":"Thyroid nodules in children: current profile of a changing disease","volume":"82","author":"Fowler","year":"1989","journal-title":"South Med J"},{"issue":"7","key":"10.1016\/j.eprac.2025.08.005_bib2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/jamaoto.2019.0898","article-title":"Pediatric thyroid cancer incidence and mortality trends in the United States, 1973-2013","volume":"145","author":"Qian","year":"2019","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"issue":"14","key":"10.1016\/j.eprac.2025.08.005_bib3","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1002\/cncr.32125","article-title":"Trends in pediatric thyroid cancer incidence in the United States, 1998-2013","volume":"125","author":"Bernier","year":"2019","journal-title":"Cancer"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib4","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1016\/j.jpeds.2014.01.059","article-title":"Increase in the incidence of differentiated thyroid carcinoma in children, adolescents, and young adults: a population-based study","volume":"164","author":"Vergamini","year":"2014","journal-title":"J Pediatr"},{"issue":"8","key":"10.1016\/j.eprac.2025.08.005_bib5","doi-asserted-by":"crossref","first-page":"3238","DOI":"10.1210\/jc.2013-1796","article-title":"A standardized assessment of thyroid nodules in children confirms higher cancer prevalence than in adults","volume":"98","author":"Gupta","year":"2013","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.005_bib6","first-page":"1039","article-title":"The 2023 Bethesda system for reporting thyroid cytopathology","volume":"33","author":"Ali","year":"2023","journal-title":"Thyroid"},{"issue":"7","key":"10.1016\/j.eprac.2025.08.005_bib7","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1089\/thy.2014.0460","article-title":"American thyroid association guidelines task F. Management guidelines for children with thyroid nodules and differentiated thyroid cancer","volume":"25","author":"Francis","year":"2015","journal-title":"Thyroid"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.005_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.4158\/EP.1.1.9","article-title":"Fine-needle aspiration biopsy: use in diagnosis and management of pediatric thyroid diseases","volume":"1","author":"Gharib","year":"1995","journal-title":"Endocr Pract"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib9","doi-asserted-by":"crossref","DOI":"10.1530\/ETJ-22-0146","article-title":"2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma","volume":"11","author":"Lebbink","year":"2022","journal-title":"Eur Thyroid J"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.005_bib10","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.eprac.2020.12.001","article-title":"Consensus statement by the American association of clinical endocrinology (AACE) and the American head and neck society endocrine surgery section (AHNS) on pediatric benign and malignant thyroid surgery","volume":"27","author":"Stack","year":"2021","journal-title":"Endocr Pract"},{"issue":"Suppl_XII","key":"10.1016\/j.eprac.2025.08.005_bib11","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.2188\/jea.JE20210271","article-title":"Thyroid ultrasound examination G. A comprehensive review of the progress and evaluation of the thyroid ultrasound examination program, the fukushima health management survey","volume":"32","author":"Shimura","year":"2022","journal-title":"J Epidemiol"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib12","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.beem.2008.09.019","article-title":"Epidemiology of thyroid nodules","volume":"22","author":"Dean","year":"2008","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"issue":"12","key":"10.1016\/j.eprac.2025.08.005_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0083220","article-title":"Investigation committee for the proportion of thyroid ultrasound F. Thyroid ultrasound findings in children from three Japanese prefectures: aomori, yamanashi and nagasaki","volume":"8","author":"Hayashida","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.eprac.2025.08.005_bib14","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1089\/thy.2018.0728","article-title":"Differences in thyroid nodule cytology and malignancy risk between children and adults","volume":"29","author":"Cherella","year":"2019","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.005_bib15","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1210\/js.2018-00287","article-title":"Influence of hashimoto thyroiditis on the development of thyroid nodules and cancer in children and adolescents","volume":"3","author":"Radetti","year":"2019","journal-title":"J Endocr Soc"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.005_bib16","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1089\/thy.2022.0241","article-title":"Autoimmune thyroiditis and risk of malignancy in children with thyroid nodules","volume":"32","author":"Keefe","year":"2022","journal-title":"Thyroid"},{"issue":"2","key":"10.1016\/j.eprac.2025.08.005_bib17","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/00000658-193008000-00002","article-title":"Biopsy by needle puncture and aspiration","volume":"92","author":"Martin","year":"1930","journal-title":"Ann Surg"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.005_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/thy.2015.0020","article-title":"2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer","volume":"26","author":"Haugen","year":"2016","journal-title":"Thyroid"},{"issue":"5","key":"10.1016\/j.eprac.2025.08.005_bib19","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jacr.2017.01.046","article-title":"ACR thyroid imaging, reporting and data system (TI-RADS): white paper of the ACR TI-RADS committee","volume":"14","author":"Tessler","year":"2017","journal-title":"J Am Coll Radiol"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib20","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.2214\/AJR.16.17613","article-title":"Multiinstitutional analysis of thyroid nodule risk stratification using the American college of radiology thyroid imaging reporting and data system","volume":"208","author":"Middleton","year":"2017","journal-title":"AJR Am J Roentgenol"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.005_bib21","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1007\/s00247-024-05982-w","article-title":"Assessment of the American college of radiology thyroid imaging reporting and data system (ACR TI-RADS) with modification of the management recommendations for pediatric thyroid nodules","volume":"54","author":"Marzukie","year":"2024","journal-title":"Pediatr Radiol"},{"issue":"21","key":"10.1016\/j.eprac.2025.08.005_bib22","doi-asserted-by":"crossref","first-page":"5304","DOI":"10.3390\/cancers13215304","article-title":"Exploring the performance of ultrasound risk stratification systems in thyroid nodules of pediatric patients","volume":"13","author":"Scappaticcio","year":"2021","journal-title":"Cancers (Basel)"},{"issue":"10","key":"10.1016\/j.eprac.2025.08.005_bib23","doi-asserted-by":"crossref","first-page":"7450","DOI":"10.1007\/s00330-021-07908-8","article-title":"Diagnostic performance of adult-based ATA and ACR-TIRADS ultrasound risk stratification systems in pediatric thyroid nodules: a systematic review and meta-analysis","volume":"31","author":"Kim","year":"2021","journal-title":"Eur Radiol"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.005_bib24","doi-asserted-by":"crossref","first-page":"270","DOI":"10.7326\/0003-4819-87-3-270_1","article-title":"Combined ultrasound and needle aspiration cytology in the assessment and management of hypofunctioning thyroid nodule","volume":"87","author":"Walfish","year":"1977","journal-title":"Ann Intern Med"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib25","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1089\/thy.2006.16.555","article-title":"Comparison of palpation-guided fine-needle aspiration biopsy to ultrasound-guided fine-needle aspiration biopsy in the evaluation of thyroid nodules","volume":"16","author":"Cesur","year":"2006","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.005_bib26","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.ecl.2017.04.011","article-title":"Thyroid cancer: ultrasound imaging and fine-needle aspiration biopsy","volume":"46","author":"Melany","year":"2017","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.005_bib27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1089\/thy.1998.8.15","article-title":"Diagnostic accuracy of conventional versus sonography-guided fine-needle aspiration biopsy of thyroid nodules","volume":"8","author":"Danese","year":"1998","journal-title":"Thyroid"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.005_bib28","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1210\/endrev\/bnaf003","article-title":"Molecular landscape and therapeutic strategies in pediatric differentiated thyroid carcinoma","volume":"46","author":"Yang","year":"2025","journal-title":"Endocr Rev"},{"issue":"5","key":"10.1016\/j.eprac.2025.08.005_bib29","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1177\/0194599816631728","article-title":"Utility of fine-needle aspiration biopsy in the evaluation of pediatric Head and neck masses","volume":"154","author":"Huyett","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"5","key":"10.1016\/j.eprac.2025.08.005_bib30","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.jasc.2023.05.005","article-title":"The 2023 Bethesda System for reporting thyroid cytopathology","volume":"12","author":"Ali","year":"2023","journal-title":"J Am Soc Cytopathol"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib31","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000351029","article-title":"Indeterminate pediatric thyroid fine needle aspirations: a study of 68 cases","volume":"57","author":"Smith","year":"2013","journal-title":"Acta Cytol"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/cncy.22104","article-title":"Incidence and malignancy rates of indeterminate pediatric thyroid nodules","volume":"127","author":"Wang","year":"2019","journal-title":"Cancer Cytopathol"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib33","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1007\/s00268-009-0364-0","article-title":"Long-term outcome in 215 children and adolescents with papillary thyroid cancer treated during 1940 through 2008","volume":"34","author":"Hay","year":"2010","journal-title":"World J Surg"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib34","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/01.sla.0000205977.74806.0b","article-title":"Comprehensive clinical assessment of 740 cases of surgically treated thyroid cancer in children of Belarus","volume":"243","author":"Demidchik","year":"2006","journal-title":"Ann Surg"},{"issue":"8","key":"10.1016\/j.eprac.2025.08.005_bib35","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1089\/thy.2020.0702","article-title":"The use of the Bethesda system for reporting thyroid cytopathology in pediatric thyroid nodules: a meta-analysis","volume":"31","author":"Vuong","year":"2021","journal-title":"Thyroid"},{"issue":"2","key":"10.1016\/j.eprac.2025.08.005_bib36","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/cjp2.38","article-title":"Molecular classification of thyroid lesions by combined testing for miRNA gene expression and somatic gene alterations","volume":"2","author":"Wylie","year":"2016","journal-title":"J Pathol Clin Res"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib37","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1097\/SLA.0000000000004130","article-title":"The clinical utility of molecular testing in the management of thyroid follicular neoplasms (Bethesda IV nodules)","volume":"272","author":"Carty","year":"2020","journal-title":"Ann Surg"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.005_bib38","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1210\/clinem\/dgaa322","article-title":"Contemporary thyroid nodule evaluation and management","volume":"105","author":"Grani","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.005_bib39","doi-asserted-by":"crossref","first-page":"e698","DOI":"10.1210\/clinem\/dgad181","article-title":"Bethesda III and IV thyroid nodules managed nonoperatively after molecular testing with Afirma GSC or thyroseq v3","volume":"108","author":"Kim","year":"2023","journal-title":"J Clin Endocrinol Metab"},{"issue":"11","key":"10.1016\/j.eprac.2025.08.005_bib40","doi-asserted-by":"crossref","first-page":"2759","DOI":"10.1210\/clinem\/dgad282","article-title":"Clinical use of molecular data in thyroid nodules and cancer","volume":"108","author":"Alzahrani","year":"2023","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.eprac.2025.08.005_bib41","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1089\/thy.2013.0640","article-title":"Centralized molecular testing for oncogenic gene mutations complements the local cytopathologic diagnosis of thyroid nodules","volume":"24","author":"Beaudenon-Huibregtse","year":"2014","journal-title":"Thyroid"},{"issue":"12","key":"10.1016\/j.eprac.2025.08.005_bib42","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1002\/dc.24564","article-title":"Multiplatform molecular test performance in indeterminate thyroid nodules","volume":"48","author":"Lupo","year":"2020","journal-title":"Diagn Cytopathol"},{"issue":"2","key":"10.1016\/j.eprac.2025.08.005_bib43","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.ecl.2017.01.014","article-title":"Molecular genetics of thyroid cancer in children and adolescents","volume":"46","author":"Bauer","year":"2017","journal-title":"Endocrinol Metab Clin North Am"},{"issue":"5","key":"10.1016\/j.eprac.2025.08.005_bib44","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1159\/000526116","article-title":"Indeterminate thyroid fine-needle aspirations in pediatrics: exploring clinicopathologic features and utility of molecular profiling","volume":"95","author":"Baran","year":"2022","journal-title":"Horm Res Paediatr"},{"issue":"7","key":"10.1016\/j.eprac.2025.08.005_bib45","doi-asserted-by":"crossref","first-page":"2743","DOI":"10.1210\/jc.2015-1158","article-title":"Molecular testing for miRNA, mRNA, and DNA on fine-needle aspiration improves the preoperative diagnosis of thyroid nodules with indeterminate cytology","volume":"100","author":"Labourier","year":"2015","journal-title":"J Clin Endocrinol Metab"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib46","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/dc.24087","article-title":"The utility of combined mutation analysis and microRNA classification in reclassifying cancer risk of cytologically indeterminate thyroid nodules","volume":"47","author":"Banizs","year":"2019","journal-title":"Diagn Cytopathol"},{"issue":"4","key":"10.1016\/j.eprac.2025.08.005_bib47","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.jasc.2020.02.002","article-title":"Clinical performance of multiplatform mutation panel and microRNA risk classifier in indeterminate thyroid nodules","volume":"9","author":"Sistrunk","year":"2020","journal-title":"J Am Soc Cytopathol"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.005_bib48","doi-asserted-by":"crossref","DOI":"10.1002\/pbc.28276","article-title":"miRNA expression can classify pediatric thyroid lesions and increases the diagnostic yield of mutation testing","volume":"67","author":"Franco","year":"2020","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.eprac.2025.08.005_bib49","doi-asserted-by":"crossref","DOI":"10.1210\/clinem\/dgaf110","article-title":"Multiplatform molecular testing as an adjunct to fine needle aspiration in the evaluation of pediatric thyroid nodules","author":"Aekka","year":"2025","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"10.1016\/j.eprac.2025.08.005_bib50","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1309\/4AXLDMN1JRPMTX5P","article-title":"Repeat thyroid nodule fine-needle aspiration in patients with initial benign cytologic results","volume":"125","author":"Flanagan","year":"2006","journal-title":"Am J Clin Pathol"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2500998X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X2500998X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T06:45:37Z","timestamp":1759301137000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X2500998X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1530891X2500998X"],"URL":"https:\/\/doi.org\/10.1016\/j.eprac.2025.08.005","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An Updated Review on the Use of Fine Needle Aspiration Biopsy in Pediatric Thyroid Disease","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eprac.2025.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 AACE. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}