{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:18:49Z","timestamp":1790313529873,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100030825","name":"Ascendis Pharma Denmark","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aacejournalendocrinepractice.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Endocrine Practice"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.eprac.2025.08.008","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T02:28:51Z","timestamp":1755743331000},"page":"1568-1575","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Early U.S. Real-World Treatment Patterns and Outcomes in Palopegteriparatide Treatment for Patients With Hypoparathyroidism"],"prefix":"10.1016","volume":"31","author":[{"given":"Timothy","family":"Graham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores M.","family":"Shoback","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Abbott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Lubitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Edelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Haider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven W.","family":"Ing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micol S.","family":"Rothman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie E.","family":"Cusano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Ukena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7534-7175","authenticated-orcid":false,"given":"Christopher T.","family":"Sibley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mishaela R.","family":"Rubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.eprac.2025.08.008_bib1","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1210\/jc.2015-3909","article-title":"Presentation of hypoparathyroidism: etiologies and clinical features","volume":"101","author":"Shoback","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"10.1016\/j.eprac.2025.08.008_bib2","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1002\/jbmr.483","article-title":"Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research","volume":"26","author":"Bilezikian","year":"2011","journal-title":"J Bone Miner Res"},{"issue":"2","key":"10.1016\/j.eprac.2025.08.008_bib3","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s40271-019-00388-5","article-title":"Assessing the patient experience of hypoparathyroidism symptoms: development of the hypoparathyroidism patient experience scale-symptom (HPES-Symptom)","volume":"13","author":"Brod","year":"2020","journal-title":"Patient"},{"key":"10.1016\/j.eprac.2025.08.008_bib4","article-title":"Hypoparathyroidism","volume":"3","author":"Mannstadt","year":"2017","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"10.1016\/j.eprac.2025.08.008_bib5","doi-asserted-by":"crossref","DOI":"10.1210\/jendso\/bvac002","article-title":"A pilot study of cognition among hypoparathyroid adults","volume":"6","author":"Rubin","year":"2022","journal-title":"J Endocr Soc"},{"issue":"9","key":"10.1016\/j.eprac.2025.08.008_bib6","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1002\/jbmr.2501","article-title":"The epidemiology of nonsurgical hypoparathyroidism in Denmark: a nationwide case finding study","volume":"30","author":"Underbjerg","year":"2015","journal-title":"J Bone Miner Res"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.008_bib7","doi-asserted-by":"crossref","DOI":"10.1530\/EC-21-0379","article-title":"Low health-related quality of life in hypoparathyroidism and need for PTH analog","volume":"11","author":"Kontogeorgos","year":"2022","journal-title":"Endocr Connect"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.008_bib8","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s11136-020-02607-1","article-title":"Living with hypoparathyroidism: development of the hypoparathyroidism patient experience scale-impact (HPES-Impact)","volume":"30","author":"Brod","year":"2021","journal-title":"Qual Life Res"},{"issue":"2","key":"10.1016\/j.eprac.2025.08.008_bib9","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s11154-020-09613-1","article-title":"Renal complications in patients with chronic hypoparathyroidism on conventional therapy: a systematic literature review: renal disease in chronic hypoparathyroidism","volume":"22","author":"Gosmanova","year":"2021","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.eprac.2025.08.008_bib11","series-title":"FORTEO\u00ae [Package insert]","year":"2020"},{"key":"10.1016\/j.eprac.2025.08.008_bib12","series-title":"FORSTEO\u00ae [summary of product characteristics]","year":"2003"},{"key":"10.1016\/j.eprac.2025.08.008_bib13","series-title":"TYMLOS\u00ae (abaloparatide) [package insert]","year":"2017"},{"key":"10.1016\/j.eprac.2025.08.008_bib14","series-title":"Eladynos\u00ae (abaloparatide) [summary of product characteristics]","year":"2022"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.008_bib15","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s12020-021-02978-6","article-title":"Teriparatide administration by the omnipod pump: preliminary experience from two cases with refractory hypoparathyroidism","volume":"76","author":"Aouchiche","year":"2022","journal-title":"Endocrine"},{"key":"10.1016\/j.eprac.2025.08.008_bib16","doi-asserted-by":"crossref","DOI":"10.12659\/AJCR.931739","article-title":"Continuous teriparatide treatment in chronic hypoparathyroidism: a case report","volume":"22","author":"Saraiva","year":"2021","journal-title":"Am J Case Rep"},{"issue":"5 Supplement","key":"10.1016\/j.eprac.2025.08.008_bib17","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1016\/j.eprac.2023.03.131","article-title":"Abstract #1407986: abaloparatide administration through the simplicity patch: a therapeutic option for refractory hypoparathyroidism post-thyroidectomy","volume":"29","author":"Chamseddin","year":"2023","journal-title":"Endocr Pract"},{"issue":"8","key":"10.1016\/j.eprac.2025.08.008_bib18","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/jbmr.4016","article-title":"A randomized double-blind placebo-controlled first-in-human phase 1 trial of TransCon PTH in healthy adults","volume":"35","author":"Karpf","year":"2020","journal-title":"J Bone Miner Res"},{"issue":"11","key":"10.1016\/j.eprac.2025.08.008_bib19","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1002\/jbmr.3824","article-title":"Design and preclinical development of TransCon PTH, an investigational sustained-release PTH replacement therapy for hypoparathyroidism","volume":"34","author":"Holten-Andersen","year":"2019","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.eprac.2025.08.008_bib21","series-title":"Ascendis pharma bone diseases A\/S","year":"2024"},{"key":"10.1016\/j.eprac.2025.08.008_bib22","series-title":"YORVIPATH\u00ae [package insert]","year":"2024"},{"key":"10.1016\/j.eprac.2025.08.008_bib23","series-title":"Yorvipath (palopegteriparatide) Solution of Injection [Product Information]","year":"2025"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.008_bib24","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1002\/jbmr.4726","article-title":"Efficacy and safety of parathyroid hormone replacement with TransCon PTH in hypoparathyroidism: 26-week results from the phase 3 PaTHway trial","volume":"38","author":"Khan","year":"2023","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.eprac.2025.08.008_bib25","article-title":"Efficacy and safety of TransCon PTH in adults with hypoparathyroidism: 52-week results from the phase 3 PaTHway trial","author":"Clarke","year":"2024","journal-title":"J Clin Endocrinol Metab"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.008_bib26","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1007\/s12325-024-02843-8","article-title":"Palopegteriparatide treatment improves renal function in adults with chronic hypoparathyroidism: 1-year results from the phase 3 PaTHway trial","volume":"41","author":"Rejnmark","year":"2024","journal-title":"Adv Ther"},{"key":"10.1016\/j.eprac.2025.08.008_bib27","series-title":"Sustained improvement in renal function with palopegteriparatide in adults with chronic hypoparathyroidism: 2-year results from the phase 3 PaTHway trial","author":"Schwarz","year":"2024"},{"issue":"12","key":"10.1016\/j.eprac.2025.08.008_bib28","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1002\/jbmr.4671","article-title":"The second international workshop on the evaluation and management of hypoparathyroidism","volume":"37","author":"Khan","year":"2022","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.eprac.2025.08.008_bib29","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1210\/clinem\/dgaa113","article-title":"Hypoparathyroidism","volume":"105","author":"Bilezikian","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"issue":"12","key":"10.1016\/j.eprac.2025.08.008_bib30","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1002\/jbmr.4691","article-title":"Evaluation and management of hypoparathyroidism summary statement and guidelines from the second international workshop","volume":"37","author":"Khan","year":"2022","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.eprac.2025.08.008_bib31","series-title":"NATPARA\u00ae [Package insert]","year":"2022"},{"issue":"1","key":"10.1016\/j.eprac.2025.08.008_bib32","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2018-000788","article-title":"Strengths and weaknesses of 'real-world' studies involving non-vitamin K antagonist oral anticoagulants","volume":"5","author":"Camm","year":"2018","journal-title":"Open Heart"},{"key":"10.1016\/j.eprac.2025.08.008_bib33","doi-asserted-by":"crossref","DOI":"10.1530\/EDM-20-0103","article-title":"The challenges of post-bariatric surgery hypocalcaemia in pre-existing hypoparathyroidism","author":"Jones","year":"2020","journal-title":"Endocrinol Diabetes Metab Case Rep"}],"container-title":["Endocrine Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X25010031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1530891X25010031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:51:24Z","timestamp":1777618284000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1530891X25010031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1530891X25010031"],"URL":"https:\/\/doi.org\/10.1016\/j.eprac.2025.08.008","relation":{},"ISSN":["1530-891X"],"issn-type":[{"value":"1530-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early U.S. Real-World Treatment Patterns and Outcomes in Palopegteriparatide Treatment for Patients With Hypoparathyroidism","name":"articletitle","label":"Article Title"},{"value":"Endocrine Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.eprac.2025.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 AACE. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}