{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T02:46:13Z","timestamp":1778899573032,"version":"3.51.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002704","name":"Fundaci\u00f3n Cient\u00edfica Asociaci\u00f3n Espa\u00f1ola Contra el C\u00e1ncer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002704","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["esmoopen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["ESMO Open"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.esmoop.2021.100157","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:54:00Z","timestamp":1619744040000},"page":"100157","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Impact of the COVID-19 pandemic on the care of cancer patients in Spain"],"prefix":"10.1016","volume":"6","author":[{"given":"M.","family":"Amador","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Matias-Guiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Sancho-Pardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Contreras Martinez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.C.","family":"de la Torre-Montero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pe\u00f1uelas Saiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Garrido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Garc\u00eda-Sanz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1.","family":"Rodr\u00edguez-Lescure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Paz-Ares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.esmoop.2021.100157_bib1","doi-asserted-by":"crossref","first-page":"102433","DOI":"10.1016\/j.jaut.2020.102433","article-title":"The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak","volume":"109","author":"Rothan","year":"2020","journal-title":"J\u00a0Autoimmun"},{"key":"10.1016\/j.esmoop.2021.100157_bib2","article-title":"Human coronavirus infections\u2014Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and SARS-CoV-2","author":"Hui","year":"2020","journal-title":"Reference Module in Biomedical Sciences"},{"key":"10.1016\/j.esmoop.2021.100157_bib3","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1002\/jmv.25678","article-title":"Outbreak of pneumonia of unknown etiology in Wuhan, China: the mystery and the miracle","volume":"92","author":"Lu","year":"2020","journal-title":"J\u00a0Med Virol"},{"issue":"SI-1","key":"10.1016\/j.esmoop.2021.100157_bib4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.3906\/sag-2004-168","article-title":"COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs","volume":"50","author":"Tufan","year":"2020","journal-title":"Turk J Med Sci"},{"key":"10.1016\/j.esmoop.2021.100157_bib6","doi-asserted-by":"crossref","first-page":"2000178","DOI":"10.2807\/1560-7917.ES.2020.25.9.2000178","article-title":"First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020","volume":"25","author":"Spiteri","year":"2020","journal-title":"Euro Surveill"},{"key":"10.1016\/j.esmoop.2021.100157_bib8","doi-asserted-by":"crossref","first-page":"100618","DOI":"10.1016\/j.cpcardiol.2020.100618","article-title":"COVID-19 and multi-organ response","author":"Zaim","year":"2020","journal-title":"Curr Probl Cardiol"},{"key":"10.1016\/j.esmoop.2021.100157_bib9","doi-asserted-by":"crossref","first-page":"m1279","DOI":"10.1136\/bmj.m1279","article-title":"Covid-19: how coronavirus will change the face of general practice forever","volume":"368","author":"Thornton","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.esmoop.2021.100157_bib11","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/bjc.2015.49","article-title":"Stage at diagnosis and early mortality from cancer in England","volume":"112","author":"McPhail","year":"2015","journal-title":"Br J Cancer"},{"key":"10.1016\/j.esmoop.2021.100157_bib12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/S1470-2045(19)30658-8","article-title":"Earlier diagnosis: the importance of cancer symptoms","volume":"21","author":"Whitaker","year":"2020","journal-title":"Lancet Oncol"},{"issue":"11","key":"10.1016\/j.esmoop.2021.100157_bib13","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/S1470-2045(20)30593-3","article-title":"A\u00a0roadmap for the early detection and diagnosis of cancer","volume":"21","author":"Crosby","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41571-020-00441-5","article-title":"COVID-19 in patients with cancer: managing a pandemic within a pandemic","volume":"18","author":"Horn","year":"2020","journal-title":"Nat Rev Clin Oncol"},{"issue":"1","key":"10.1016\/j.esmoop.2021.100157_bib15","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1182\/blood-2020-142292","article-title":"Impact of Sars-CoV2 infection on 491 hematological patients: the Ecovidehe multicenter study","volume":"136","author":"De Ram\u00f3n","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.esmoop.2021.100157_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40164-020-00177-z","article-title":"Risk factors and outcome of COVID-19 in patients with hematological malignancies","volume":"9","author":"Pi\u00f1ana","year":"2020","journal-title":"Exp Hematol Oncol"},{"issue":"1","key":"10.1016\/j.esmoop.2021.100157_bib17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s13045-020-00970-7","article-title":"Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study","volume":"13","author":"Garc\u00eda-Su\u00e1rez","year":"2020","journal-title":"J\u00a0Hematol Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib18","series-title":"Cancer Patient Experience Survey 2020: The impact of COVID-19 on cancer patients in the UK","year":"2020"},{"key":"10.1016\/j.esmoop.2021.100157_bib19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41571-020-00446-0","article-title":"Consequences of COVID-19 for cancer care \u2013 a CRUK perspective","volume":"18","author":"Greenwood","year":"2020","journal-title":"Nat Rev Clin Oncol"},{"issue":"6","key":"10.1016\/j.esmoop.2021.100157_bib20","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S1470-2045(20)30265-5","article-title":"Fewer cancer diagnoses during the COVID-19 epidemic in the Netherlands","volume":"21","author":"Dinmohamed","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib21","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1200\/GO.20.00351","article-title":"Impact of the COVID-19 pandemic on cancer care: a global collaborative study","volume":"6","author":"Jazieh","year":"2020","journal-title":"JCO Glob Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib22","series-title":"SAS\/ACCESS\u00ae 9.4 Interface to ADABAS: Reference. [computer software]. Version 9.4","year":"2013"},{"key":"10.1016\/j.esmoop.2021.100157_bib24","doi-asserted-by":"crossref","first-page":"e251","DOI":"10.1016\/S2468-2667(20)30060-8","article-title":"The resilience of the Spanish health system against the COVID-19 pandemic","volume":"5","author":"Legido-Quigley","year":"2020","journal-title":"Lancet Public Health"},{"issue":"10250","key":"10.1016\/j.esmoop.2021.100157_bib26","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(20)31483-5","article-title":"Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study","volume":"396","author":"Poll\u00e1n","year":"2020","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.esmoop.2021.100157_bib27","doi-asserted-by":"crossref","first-page":"e2029058","DOI":"10.1001\/jamanetworkopen.2020.29058","article-title":"Risk factors associated with in-hospital mortality in a US national sample of patients with COVID-19","volume":"3","author":"Rosenthal","year":"2020","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.esmoop.2021.100157_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12094-020-02381-z","article-title":"Covid-19 transmission, outcome and associated risk factors in cancer patients at the first month of the pandemic in a Spanish hospital in Madrid","volume":"22","author":"Rogado","year":"2020","journal-title":"Clin Transl Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib29","doi-asserted-by":"crossref","first-page":"m4087","DOI":"10.1136\/bmj.m4087","article-title":"Mortality due to cancer treatment delay: systematic review and meta-analysis","volume":"371","author":"Hanna","year":"2020","journal-title":"BMJ"},{"key":"10.1016\/j.esmoop.2021.100157_bib30","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1126\/science.abd3377","article-title":"COVID-19 and cancer","volume":"368","author":"Sharpless","year":"2020","journal-title":"Science"},{"issue":"8","key":"10.1016\/j.esmoop.2021.100157_bib31","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S1470-2045(20)30388-0","article-title":"The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study","volume":"21","author":"Maringe","year":"2020","journal-title":"Lancet Oncol"},{"issue":"2","key":"10.1016\/j.esmoop.2021.100157_bib32","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1200\/JCO.20.02953","article-title":"American Society of Clinical Oncology road to recovery report: learning from the COVID-19 experience to improve clinical research and cancer care","volume":"39","author":"Pennell","year":"2021","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.esmoop.2021.100157_bib33","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ijsu.2020.04.018","article-title":"The socio-economic implications of the coronavirus pandemic (COVID-19): a review","volume":"78","author":"Nicola","year":"2020","journal-title":"Int J Surg"},{"key":"10.1016\/j.esmoop.2021.100157_bib36","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0140-6736(20)32656-8","article-title":"6-month consequences of COVID-19 in patients discharged from hospital: a cohort study","volume":"397","author":"Huang","year":"2021","journal-title":"Lancet"}],"container-title":["ESMO Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2059702921001174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2059702921001174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T20:26:41Z","timestamp":1761856001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2059702921001174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S2059702921001174"],"URL":"https:\/\/doi.org\/10.1016\/j.esmoop.2021.100157","relation":{},"ISSN":["2059-7029"],"issn-type":[{"value":"2059-7029","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of the COVID-19 pandemic on the care of cancer patients in Spain","name":"articletitle","label":"Article Title"},{"value":"ESMO Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.esmoop.2021.100157","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd on behalf of European Society for Medical Oncology.","name":"copyright","label":"Copyright"}],"article-number":"100157"}}