{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T22:32:58Z","timestamp":1786746778597,"version":"build-2736575974"},"reference-count":13,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["esmoopen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["ESMO Open"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.esmoop.2025.106020","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T19:23:38Z","timestamp":1767036218000},"page":"106020","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluating MRI response criteria in microsatellite instability-high rectal cancer treated with immune checkpoint inhibitors"],"prefix":"10.1016","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8024-3445","authenticated-orcid":false,"given":"Q.","family":"Vanderbecq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9602-5162","authenticated-orcid":false,"given":"R.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2566-3866","authenticated-orcid":false,"given":"M.","family":"Camus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Dray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Parc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5103-7095","authenticated-orcid":false,"given":"T.","family":"Andr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"23","key":"10.1016\/j.esmoop.2025.106020_bib1","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1056\/NEJMoa2017699","article-title":"Pembrolizumab in microsatellite-instability-high advanced colorectal cancer","volume":"383","author":"Andr\u00e9","year":"2020","journal-title":"N Engl J Med"},{"issue":"10476","key":"10.1016\/j.esmoop.2025.106020_bib2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0140-6736(24)02848-4","article-title":"Nivolumab plus ipilimumab versus nivolumab in microsatellite instability-high metastatic colorectal cancer (CheckMate 8HW): a randomised, open-label, phase 3 trial","volume":"405","author":"Andr\u00e9","year":"2025","journal-title":"Lancet"},{"issue":"21","key":"10.1016\/j.esmoop.2025.106020_bib3","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1056\/NEJMoa2402141","article-title":"Nivolumab plus ipilimumab in microsatellite-instability\u2013high metastatic colorectal cancer","volume":"391","author":"Andr\u00e9","year":"2024","journal-title":"N Eng J Med"},{"issue":"23","key":"10.1016\/j.esmoop.2025.106020_bib4","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1056\/NEJMoa2404512","article-title":"Nonoperative management of mismatch repair-deficient tumors","volume":"392","author":"Cercek","year":"2025","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.esmoop.2025.106020_bib5","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.221529","article-title":"Watch-and-wait approach to rectal cancer: the role of imaging","volume":"307","author":"Jayaprakasam","year":"2023","journal-title":"Radiology"},{"issue":"23","key":"10.1016\/j.esmoop.2025.106020_bib6","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1200\/JCO.22.00032","article-title":"Organ preservation in patients with rectal adenocarcinoma treated with total neoadjuvant therapy","volume":"40","author":"Garcia-Aguilar","year":"2022","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1016\/j.esmoop.2025.106020_bib7","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.232908","article-title":"MRI tumor regression response to neoadjuvant chemotherapy alone without radiation for rectal adenocarcinoma","volume":"312","author":"Shen","year":"2024","journal-title":"Radiology"},{"key":"10.1016\/j.esmoop.2025.106020_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejca.2020.11.009","article-title":"Pseudoprogression in patients treated with immune checkpoint inhibitors for microsatellite instability-high\/mismatch repair-deficient metastatic colorectal cancer","volume":"144","author":"Colle","year":"2021","journal-title":"Eur J Cancer"},{"issue":"3","key":"10.1016\/j.esmoop.2025.106020_bib9","doi-asserted-by":"crossref","first-page":"e143","DOI":"10.1016\/S1470-2045(17)30074-8","article-title":"iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics","volume":"18","author":"Seymour","year":"2017","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.esmoop.2025.106020_bib10","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s41747-019-0134-1","article-title":"Imaging of tumour response to immunotherapy","volume":"4","author":"Dromain","year":"2020","journal-title":"Eur Radiol Exp"},{"issue":"2","key":"10.1016\/j.esmoop.2025.106020_bib11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.6004\/jnccn.2022.7071","article-title":"Prevalent pseudoprogression and pseudoresidue in patients with rectal cancer treated with neoadjuvant immune checkpoint inhibitors","volume":"21","author":"Xie","year":"2023","journal-title":"J Natl Compr Canc Netw"},{"issue":"1","key":"10.1016\/j.esmoop.2025.106020_bib12","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2214\/AJR.18.20864","article-title":"Mucin-containing rectal carcinomas: overview of unique clinical and imaging features","volume":"213","author":"Wnorowski","year":"2019","journal-title":"AJR Am J Roentgenol"},{"issue":"4","key":"10.1016\/j.esmoop.2025.106020_bib13","doi-asserted-by":"crossref","DOI":"10.1172\/JCI170490","article-title":"68Ga-FAPI PET imaging monitors response to combined TGF-\u03b2R inhibition and immunotherapy in metastatic colorectal cancer","volume":"134","author":"Li","year":"2024","journal-title":"J Clin Invest"}],"container-title":["ESMO Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2059702925018903?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2059702925018903?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T08:36:10Z","timestamp":1768811770000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2059702925018903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S2059702925018903"],"URL":"https:\/\/doi.org\/10.1016\/j.esmoop.2025.106020","relation":{},"ISSN":["2059-7029"],"issn-type":[{"value":"2059-7029","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluating MRI response criteria in microsatellite instability-high rectal cancer treated with immune checkpoint inhibitors","name":"articletitle","label":"Article Title"},{"value":"ESMO Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.esmoop.2025.106020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Ltd on behalf of European Society for Medical Oncology.","name":"copyright","label":"Copyright"}],"article-number":"106020"}}