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The questionnaire addressed medical history, socioeconomic status, sexual performance satisfaction before and during the lockdown in addition to validated Arabic questionnaires for depression, sexual function in males and females, and sexual satisfaction (Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Female Sexual Function Index, International Index of Erectile Function-5, Index of Sexual Satisfaction, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measure<\/jats:title><jats:p>The main outcome measures were frequency of depression, anxiety, sexual dysfunction, and sexual satisfaction in males and females during COVID-19 lockdown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 479 females and 217 males completed the questionnaire. Sexual satisfaction was significantly higher before (91.2%, 73.5%) than during lockdown (70.5%, 56.2%) in both males and females, respectively. During lockdown, significantly more males (70.5%) reported being satisfied with their sexual performance than females (56.2%) (P\u00a0&amp;lt;\u00a0.001). More than half of the male subjects (68.2%) had no erectile dysfunction while 97.3% females scored \u226426.5 on the Female Sexual Function Index scale suggestive of sexual difficulties. Sexual stress was significantly greater in females (70.8%) than males (63.1%). Educational level, occupation, anxiety, and erectile dysfunction were independently associated with sexual stress in males. Being a housewife or unemployed, husband's age &amp;gt;35\u00a0years, marriage duration of 5-10\u00a0years, anxiety, and female sexual dysfunction were predictors of sexual relation stress in females.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>COVID-19 pandemic was associated with lower sexual satisfaction in both genders. Females however suffered more anxiety and depression and thereby greater risk of sexual function difficulties and sexual dissatisfaction. Intervention strategies in order to lessen the suffering of affected individuals particularly after the pandemic are recommended.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.esxm.2020.100295","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T20:28:08Z","timestamp":1610483288000},"page":"100295-100295","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Psychological and Sexual Health During the COVID-19 Pandemic in Egypt: Are Women Suffering More?"],"prefix":"10.1093","volume":"9","author":[{"given":"Salma Samir","family":"Omar","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology & Andrology, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"Dawood","sequence":"additional","affiliation":[{"name":"Department of Urology, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha","family":"Eid","sequence":"additional","affiliation":[{"name":"Department of Gynaecology & Obstetrics, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalia","family":"Eldeeb","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"Munir","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"Arafat","sequence":"additional","affiliation":[{"name":"Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine, Alexandria University , Alexandria , Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,1,9]]},"reference":[{"key":"2023010721371072100_bib1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/pcn.12988","article-title":"Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations","volume":"74","author":"Shigemura","year":"2020","journal-title":"Psychiatry Clin Neurosci"},{"key":"2023010721371072100_bib2","article-title":"Egypt Care: Corona Virus in Egypt"},{"key":"2023010721371072100_bib3","article-title":"Mental health and covid-19","author":"WHO","year":"2020"},{"key":"2023010721371072100_bib4","article-title":"Novel Coronavirus (2019-nCoV) technical guidance;","author":"WHO","year":"2020"},{"key":"2023010721371072100_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s13293-020-00330-7","article-title":"Sex differences in severity and mortality from COVID-19: are males more vulnerable?","volume":"11","author":"Pradhan","year":"2020","journal-title":"Biol Sex Differ"},{"key":"2023010721371072100_bib6","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/S2215-0366(20)30073-0","article-title":"Psychological interventions for people affected by the COVID-19 epidemic","volume":"7","author":"Duan","year":"2020","journal-title":"Lancet Psychiatry"},{"key":"2023010721371072100_bib7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jad.2020.07.141","article-title":"Psychological distress related to COVID-19 - the contribution of continuous traumatic stress","volume":"277","author":"Lahav","year":"2020","journal-title":"J\u00a0Affect Disord"},{"key":"2023010721371072100_bib8","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S0140-6736(20)30673-5","article-title":"COVID-19: towards controlling of a pandemic","volume":"395","author":"Bedford","year":"2020","journal-title":"Lancet"},{"key":"2023010721371072100_bib9","article-title":"International ethical guidelines for epidemiological studies. 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