{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:49:29Z","timestamp":1786988969824,"version":"build-2736575974"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T00:00:00Z","timestamp":1672790400000},"content-version":"vor","delay-in-days":545,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T00:00:00Z","timestamp":1625702400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T00:00:00Z","timestamp":1623024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"National Institutes of Health National Cancer Institute to Memorial Sloan Kettering Cancer Center","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}]},{"DOI":"10.13039\/100016945","name":"Sidney Kimmel Center for Prostate and Urologic Cancers","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100016945","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA008748"],"award-info":[{"award-number":["P30 CA008748"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["smoa.jsexmed.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Penile pain is one of the most stressful symptoms in men with Peyronie's disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the prevalence, clinical presentation and risk factors associated with penile pain in men with PD as well as to assess the psychosocial impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We revised our institution's database of men diagnosed with PD. The information collected included penile pain assessments, and the scores of the PD Questionnaire (PDQ), Self-Esteem and Relationship Questionnaire (SEAR) and Center for Epidemiologic Studies Depression Scale Questionnaire (CES-D). Descriptive and comparative statistics were used. Logistic regression analyses were performed to evaluate predictive factors associated with penile pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome measures<\/jats:title>\n                    <jats:p>Penile pain descriptive assessment and factors associated with penile pain in men with PD. Comparison of SEAR, CES-D and PDQ domain scores of men with and without penile pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>431 men with PD were included for this analysis with a mean age of 55.9 years. Penile pain was reported by 36.7%; 65.2% of those had painful erection, 7% pain with flaccid state only, and 20% in both stages. The median pain severity was 3 with erection and 1 with flaccid stage. After adjusted logistic regression analyses, advanced age was associated with less pain (OR 0.94, P \u2264 0.001). Men with penile pain had no significant difference in CES-D and SEAR mean scores compared to men without penile pain. The PDQ scores for the physical\/psychological symptoms domain and the bother domain were significantly higher in men with penile pain (12 vs 8.7; P &amp;lt; 0.01 and 9 vs 7.1; P &amp;lt; 0.01 respectively). Men with penile pain had a higher rate of clinically significant bother scores than men without penile pain (52% vs 35%, P \u2264 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Penile pain is common in men with PD. It was more common in young men and was associated with physical and psychological bothers in this population.<\/jats:p>\n                    <jats:p>Flores JM, Salter CA, Nascimento B, et al. The Prevalence and Predictors of Penile Pain in Men with Peyronie's Disease. Sex Med 2021;9:100398.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.esxm.2021.100398","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T19:53:18Z","timestamp":1625773998000},"page":"100398-100398","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["The Prevalence and Predictors of Penile Pain in Men with Peyronie's Disease"],"prefix":"10.1093","volume":"9","author":[{"given":"Jose M.","family":"Flores","sequence":"first","affiliation":[{"name":"Sexual & Reproductive Medicine Program , New York, New York ,"},{"name":"Urology Service, Memorial Sloan Kettering Cancer Center , New York, New York ,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn A.","family":"Salter","sequence":"additional","affiliation":[{"name":"Sexual & Reproductive Medicine Program , New York, New York ,"},{"name":"Urology Service, Memorial Sloan Kettering Cancer Center , New 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L.","family":"Bernie","sequence":"additional","affiliation":[{"name":"Sexual & Reproductive Medicine Program , New York, New York ,"},{"name":"Urology Service, Memorial Sloan Kettering Cancer Center , New York, New York ,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Miranda","sequence":"additional","affiliation":[{"name":"Sexual & Reproductive Medicine Program , New York, New York ,"},{"name":"Urology Service, Memorial Sloan Kettering Cancer Center , New York, New York ,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Sexual & Reproductive Medicine Program , New York, New York ,"},{"name":"Urology Service, Memorial Sloan Kettering Cancer Center , New York, New York ,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Schofield","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral 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