{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:28:22Z","timestamp":1791271702215,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2004,9]]},"DOI":"10.1016\/j.etap.2004.04.005","type":"journal-article","created":{"date-parts":[[2004,6,29]],"date-time":"2004-06-29T12:40:56Z","timestamp":1088512856000},"page":"1-7","source":"Crossref","is-referenced-by-count":27,"title":["Toxic effects of pulp and paper-mill effluents on male reproductive organs and some systemic parameters in rats"],"prefix":"10.1016","volume":"18","author":[{"given":"Tanu","family":"Rana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashank","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhiraj","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharad","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Rana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikram S","family":"Rathore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben M.J","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2004.04.005_BIB1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0166-445X(00)00101-6","article-title":"Effects of primary- and secondary-treated bleached kraft mill effluents on the immune system and physiological parameters of roach","volume":"51","author":"Aaltonen","year":"2000","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0147-6513(92)90011-Q","article-title":"Responses of fish populations and communities to pulp mill effluents: a holistic assessment","volume":"24","author":"Adams","year":"1992","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"2","key":"10.1016\/j.etap.2004.04.005_BIB3","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1093-0191(00)00055-1","article-title":"Aquatic toxicity from pulp and paper mill effluents: a review","volume":"5","author":"Ali","year":"2001","journal-title":"Adv. Environ. Res."},{"key":"10.1016\/j.etap.2004.04.005_BIB4","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0045-6535(00)00594-4","article-title":"Microsomal monooxygenase activity in Tilapia (Oreochromis mossambicus) exposed to a bleached kraft mill effluent using different exposure systems","volume":"45","author":"Chen","year":"2001","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2004.04.005_BIB5","unstructured":"Clesceri, L.S., Greenberg, A.E., Trusel, R.R. (Eds.), 1989. Standard methods for the examination of water and waterwastes, 17th ed. American Public Health Association, Washington, DC."},{"key":"10.1016\/j.etap.2004.04.005_BIB6","unstructured":"CPPA, 1974. Technical Section Standard Method H5P. Canadian Pulp and Paper Association, Montreal, Canada."},{"key":"10.1016\/j.etap.2004.04.005_BIB7","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/BF01701943","article-title":"Laboratory induction of intersexuality in the mosquitofish, Gambusia affinis, using paper mill effluent","volume":"43","author":"Drysdale","year":"1989","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB8","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1002\/etc.5620210927","article-title":"Evaluation of androstenedione as an androgenic component of river water downstream of a pulp and paper mill effluent","volume":"21","author":"Durhan","year":"2002","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB9","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1006\/eesa.1995.1021","article-title":"Biochemical and physiological effects in fish exposed to bleached kraft mill effluents","volume":"30","author":"Forlin","year":"1995","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2004.04.005_BIB10","first-page":"584","article-title":"A modification of the Roe procedure for the determination of fructose in tissues with increased specificity","volume":"56","author":"Foreman","year":"1973","journal-title":"Anal. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB11","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/etc.5620200622","article-title":"Identification of androstenedione in a river containing paper mill effluent","volume":"20","author":"Jenkins","year":"2001","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB12","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s001280000084","article-title":"Impact of mechanical pulp mill effluent on egg hatchability of brown trout","volume":"64","author":"Johnsen","year":"2000","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB13","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0269-7491(01)00120-8","article-title":"Fish community responses to pulp and paper mill effluents at the southern Lake Saimaa, Finland","volume":"116","author":"Karels","year":"2002","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.etap.2004.04.005_BIB14","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1002\/etc.5620200715","article-title":"Reproductive, biochemical, physiological, and population responses in perch (Perca fluviatilis L.) and roach (Rutilus rutilus L.) downstream of two elemental chlorine-free pulp and paper mills","volume":"20","author":"Karels","year":"2001","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB15","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.watres.2003.10.051","article-title":"Fate of wood extractives in wastewater treatment plants at kraft pulp mills and mechanical pulp mills","volume":"38","author":"Kostamo","year":"2004","journal-title":"Water Res."},{"key":"10.1016\/j.etap.2004.04.005_BIB16","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/00984109708984029","article-title":"Perspectives on Canadian field studies examining the potential of pulp and paper mill effluent to affect fish reproduction","volume":"51","author":"Kovacs","year":"1997","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.etap.2004.04.005_BIB17","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0269-7491(01)00205-6","article-title":"Assessing the biological status of fish in a river receiving pulp and paper mill effluents","volume":"118","author":"Kovacs","year":"2002","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.etap.2004.04.005_BIB18","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1289\/ehp.02110739","article-title":"Male-biased sex ratios of fish embryos near a pulp mill: temporary recovery after a short-term shutdown","volume":"110","author":"Larsson","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2004.04.005_BIB19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1006\/eesa.2001.2139","article-title":"Studies of masculinization, detoxification, and oxidative stress responses in guppies (Poecilia reticulata) exposed to effluent from a pulp mill","volume":"52","author":"Larsson","year":"2002","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2004.04.005_BIB20","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1136\/oem.59.6.373","article-title":"Effluents from a pulp and paper mill: a skin and health survey of children living in upstream and downstream villages","volume":"59","author":"Lee","year":"2002","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.etap.2004.04.005_BIB21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0166-445X(90)90037-P","article-title":"Biotransformation and other toxicological and physiological responses in rainbow trout (Salmo gairdneri Richardson) caged in a lake receiving effluents of pulp and paper industry","volume":"16","author":"Lindstr\u00f6m-Sepp\u00e4","year":"1990","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB22","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0147-6513(92)90025-X","article-title":"Milt characteristics, reproductive performance, and larval survival and development of white sucker exposed to bleached kraft mill effluent","volume":"23","author":"McMaster","year":"1992","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2004.04.005_BIB23","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1006\/eesa.2001.2049","article-title":"Effects of pulp mill effluents and restricted diet on growth and physiology of rainbow trout (Oncorhynchus mykiss)","volume":"49","author":"Mattsson","year":"2001","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2004.04.005_BIB24","doi-asserted-by":"crossref","unstructured":"Mortimer, D., 1994. Practical Laboratory Andrology. Oxford University Press, Oxford.","DOI":"10.1093\/oso\/9780195065954.001.0001"},{"key":"10.1016\/j.etap.2004.04.005_BIB25","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1080\/10937409809524558","article-title":"An overview of recent studies on the potential of pulp-mill effluents to alter reproductive parameters in fish","volume":"1","author":"Munkittrick","year":"1998","journal-title":"J. Toxicol. Environ. Health. B Crit. Rev."},{"key":"10.1016\/j.etap.2004.04.005_BIB26","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/toxsci\/62.2.257","article-title":"Masculinization of female mosquitofish in Kraft mill effluent-contaminated Fenholloway River water is associated with androgen receptor agonist activity","volume":"62","author":"Parks","year":"2001","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.etap.2004.04.005_BIB27","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0739-7240(02)00155-8","article-title":"Endocrine disrupting compounds and farm animals: their properties, actions and routes of exposure","volume":"23","author":"Rhind","year":"2002","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.etap.2004.04.005_BIB28","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0021-9258(18)57202-1","article-title":"A rapid method for the determination of citric acid","volume":"175","author":"Saffron","year":"1948","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB29","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s002440010274","article-title":"Assessment of reproductive effects in largemouth bass (Micropterus salmoides) exposed to bleached\/unbleached kraft mill effluents","volume":"41","author":"Sepulveda","year":"2001","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB30","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/etc.5620220127","article-title":"Effects of pulp and paper mill effluents on reproductive success of largemouth bass","volume":"22","author":"Sepulveda","year":"2003","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB31","first-page":"283","article-title":"Assessment of the pulp and paper mill effluent on growth, yield and nutrient quality of wheat (Triticum aestivum L.)","volume":"23","author":"Singh","year":"2002","journal-title":"J. Environ. Biol."},{"key":"10.1016\/j.etap.2004.04.005_BIB32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1007\/BF01623577","article-title":"Impact of pulp and paper mill effluent on egg hatchability of pike (Esox lucius L.)","volume":"36","author":"Tana","year":"1986","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.etap.2004.04.005_BIB33","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1139\/o76-051","article-title":"Acid phosphatases: androgen dependent markers of rat prostate","volume":"54","author":"Tenniswood","year":"1976","journal-title":"Can. J. Biochem."},{"key":"10.1016\/j.etap.2004.04.005_BIB34","first-page":"85","article-title":"Role of luminal fluid glycosyltransferases and glycosidases in the modification of rat sperm plasma membrane glycoproteins during epididymal maturation","volume":"53","author":"Tulsiani","year":"1998","journal-title":"J. Reprod. Fertil. Suppl."},{"key":"10.1016\/j.etap.2004.04.005_BIB35","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1002\/etc.5620211112","article-title":"Timing of exposure to a pulp and paper effluent influences the manifestation of reproductive effects in rainbow trout","volume":"21","author":"van den Heuvel","year":"2002","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.etap.2004.04.005_BIB36","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1006\/eesa.2001.2130","article-title":"Exposure of reproductively maturing rainbow trout to a New Zealand pulp and paper mill effluent","volume":"51","author":"van den Heuvel","year":"2002","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.etap.2004.04.005_BIB37","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/0041-008X(92)90327-O","article-title":"Exposure to bleached kraft pulp mill effluent disrupts the pituitary-gonadal axis of white sucker at multiple sites","volume":"115","author":"Van der Kraak","year":"1992","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etap.2004.04.005_BIB38","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0041-008X(02)00045-5","article-title":"Competitive interactions of chlorinated phenol compounds with 3,3\u2032,5-triiodothyronine binding to transthyretin: detection of possible thyroid-disrupting chemicals in environmental waste water","volume":"187","author":"Yamauchi","year":"2003","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etap.2004.04.005_BIB39","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0160-4120(02)00075-2","article-title":"Occurrence and fate of hormone steroids in the environment","volume":"28","author":"Yin","year":"2002","journal-title":"Environ. Int."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668904000717?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668904000717?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T14:43:59Z","timestamp":1705157039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668904000717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["S1382668904000717"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2004.04.005","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2004,9]]}}}