{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:23:29Z","timestamp":1777541009283,"version":"3.51.4"},"reference-count":32,"publisher":"Elsevier BV","issue":"3","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.etap.2013.09.022","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T03:15:26Z","timestamp":1381547726000},"page":"1176-1185","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus\u2013pituitary\u2013thyroid axis in zebrafish larvae"],"prefix":"10.1016","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0576-0992","authenticated-orcid":false,"given":"Xuesong","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shutao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongmei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.etap.2013.09.022_bib0005","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.tox.2010.03.006","article-title":"Effects of exposure to BDE-99 on oxidative status of liver and kidney in adult rats","volume":"271","author":"Albina","year":"2010","journal-title":"Toxicology"},{"key":"10.1016\/j.etap.2013.09.022_bib0010","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.etap.2007.12.004","article-title":"Environmental exposure to PBDEs and thyroid function among New York anglers","volume":"25","author":"Blooma","year":"2008","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.etap.2013.09.022_bib0015","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1530\/eje.1.02128","article-title":"Environmental chemicals and thyroid unction","volume":"154","author":"Boas","year":"2006","journal-title":"Eur. J. Endocrinol."},{"key":"10.1016\/j.etap.2013.09.022_bib0020","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.aquatox.2011.10.013","article-title":"Disruption of the hypothalamic\u2013pituitary\u2013thyroid axis in zebrafish embryo-larvae following waterborne exposure to BDE-47, TBBPA and BPA","volume":"108","author":"Chan","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0025","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.aquatox.2012.01.008","article-title":"Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae","volume":"110","author":"Chen","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0030","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ygcen.2004.07.004","article-title":"Developmental changes of thyroid hormones in the fathead minnow, Pimephales promelas","volume":"139","author":"Crane","year":"2004","journal-title":"Gen. Comp. Endocr."},{"key":"10.1016\/j.etap.2013.09.022_bib0035","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.ygcen.2005.10.014","article-title":"Role of corticotropin-releasing hormone as a thyrotropin-releasing factor in non-mammalian vertebrates","volume":"146","author":"De Groef","year":"2006","journal-title":"Gen. Comp. Endocr."},{"key":"10.1016\/j.etap.2013.09.022_bib0040","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.marpolbul.2009.09.006","article-title":"Effects of individual polybrominated diphenyl ether (PBDE) congeners on harbour seal immune cells in vitro","volume":"60","author":"Frouin","year":"2010","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.etap.2013.09.022_bib0045","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.cbpb.2006.05.003","article-title":"Trans-activation activity of thyroid hormone receptors in fish (Conger myriaster) in response to thyroid hormones","volume":"144B","author":"Kawakami","year":"2006","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1016\/j.etap.2013.09.022_bib0050","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/toxsci\/kfq105","article-title":"Developmental exposure to a commercial PBDE mixture, DE-71: neurobehavioral, hormonal, and reproductive effects","volume":"116","author":"Kodavanti","year":"2010","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.etap.2013.09.022_bib0055","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1677\/JOE-08-0472","article-title":"Thyroid hormone regulation of mRNAs encoding thyrotropin beta-subunit, glycoprotein alpha-subunit, and thyroid hormone receptors alpha and beta in brain, pituitary gland, liver, and gonads of an adult teleost, Pimephales promelas","volume":"202","author":"Lema","year":"2009","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.etap.2013.09.022_bib0060","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.chemosphere.2007.11.036","article-title":"Arsenate and perchlorate toxicity, growth effects, and thyroid histopathology in hypothyroid zebrafish Danio rerio","volume":"71","author":"Liu","year":"2008","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2013.09.022_bib0065","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.etap.2011.09.002","article-title":"Changes of thyroid hormone levels and related gene expression in zebrafish on early life stage exposure to triadimefon","volume":"32","author":"Liu","year":"2011","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.etap.2013.09.022_bib0070","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1046\/j.1432-0436.2002.700104.x","article-title":"Thyroid hormones are important for embryonic to larval transitory phase in zebrafish","volume":"70","author":"Liu","year":"2002","journal-title":"Differentiation"},{"key":"10.1016\/j.etap.2013.09.022_bib0075","first-page":"87","article-title":"Disruption of the thyroid system by diethystilbestrol and ioxynil in the sea bream (Sparus aurata)","volume":"94","author":"Morgado","year":"2009","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0080","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1089\/thy.2005.15.799","article-title":"Thyroid hormone deiodination in fish","volume":"15","author":"Orozco","year":"2005","journal-title":"Thyroid"},{"key":"10.1016\/j.etap.2013.09.022_bib0085","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.aquatox.2011.11.004","article-title":"Effects of the anti-thyroidal compound potassium-perchlorate on the thyroid system of the zebrafish","volume":"109","author":"Schmidt","year":"2012","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0090","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/j.chemosphere.2009.07.074","article-title":"Waterborne exposure to PFOS causes disruption of the hypothalamus\u2013pituitary\u2013thyroid axis in zebrafish larvae","volume":"77","author":"Shi","year":"2009","journal-title":"Chemosphere"},{"key":"10.1016\/j.etap.2013.09.022_bib0095","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/toxsci\/kfn230","article-title":"Effects of perinatal PBDE exposure on hepatic phase I, phase II, phase III, and deiodinase 1 gene expression involved in thyroid hormone metabolism in male rat pups","volume":"107","author":"Szabo","year":"2009","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.etap.2013.09.022_bib0100","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.tiv.2009.08.020","article-title":"Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells","volume":"24","author":"Tagliaferri","year":"2010","journal-title":"Toxicol. In Vitro"},{"key":"10.1016\/j.etap.2013.09.022_bib0105","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1021\/es035070v","article-title":"Bioaccumulation, biotransformation, and biochemical effects of brominated diphenyl ethers in juvenile lake trout (Salvelinus namaycush)","volume":"38","author":"Tomy","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.etap.2013.09.022_bib0110","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1210\/en.2002-220744","article-title":"Anion selectivity by the sodium iodide symporter","volume":"144","author":"Van Sande","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.etap.2013.09.022_bib0115","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1021\/es061408k","article-title":"Biomagnification of PBDEs in three small terrestrial food chains","volume":"41","author":"Voorspoels","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.etap.2013.09.022_bib0120","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1093\/toxsci\/kfr068","article-title":"Interaction of PFOS and BDE-47 co-exposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains","volume":"121","author":"Wang","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.etap.2013.09.022_bib0125","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/tox.20655","article-title":"The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat","volume":"27","author":"Wu","year":"2012","journal-title":"Environ. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0130","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S1001-0742(11)60758-4","article-title":"A review of polybrominated diphenyl ethers and alternative brominated flame retardants in wildlife from China: levels, trends, and bioaccumulation characteristics","volume":"24","author":"Wu","year":"2012","journal-title":"J. Environ. Sci. China"},{"key":"10.1016\/j.etap.2013.09.022_bib0135","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.etap.2012.10.004","article-title":"Effects of acute exposure to polybrominated diphenyl ethers on retinoid signaling in zebrafish larvae","volume":"35","author":"Xu","year":"2013","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.etap.2013.09.022_bib0140","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.aquatox.2009.10.022","article-title":"Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic\u2013pituitary\u2013thyroid axis of zebrafish larvae","volume":"97","author":"Yu","year":"2010","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.etap.2013.09.022_bib0145","doi-asserted-by":"crossref","first-page":"10652","DOI":"10.1021\/es2026592","article-title":"Parental transfer of polybrominated diphenyl ethers (PBDEs) and thyroid endocrine disruption in zebrafish","volume":"45","author":"Yu","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.etap.2013.09.022_bib0150","doi-asserted-by":"crossref","first-page":"6947","DOI":"10.1021\/es101354g","article-title":"Perchlorate and iodide in whole blood samples from infants, children, and adults in Nanchang, China","volume":"44","author":"Zhang","year":"2010","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.etap.2013.09.022_bib0155","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/toxsci\/61.1.76","article-title":"Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats","volume":"61","author":"Zhou","year":"2001","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.etap.2013.09.022_bib0160","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/10408440601123446","article-title":"General background on the hypothalamic\u2013pituitary\u2013thyroid (HPT) axis","volume":"37","author":"Zoeller","year":"2007","journal-title":"Crit. Rev. Toxicol."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668913002147?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668913002147?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T02:50:16Z","timestamp":1539312616000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668913002147"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S1382668913002147"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2013.09.022","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus\u2013pituitary\u2013thyroid axis in zebrafish larvae","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2013.09.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}