{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T04:40:04Z","timestamp":1716352804206},"reference-count":61,"publisher":"Elsevier BV","issue":"1","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Environmental Toxicology and Pharmacology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.etap.2013.11.029","type":"journal-article","created":{"date-parts":[[2013,12,25]],"date-time":"2013-12-25T21:00:13Z","timestamp":1388005213000},"page":"378-389","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Physiologically based toxicokinetic modeling of secondary acute myelolytic leukemia"],"prefix":"10.1016","volume":"37","author":[{"given":"Manas Kumar","family":"Mukhopadhyay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debjani","family":"Nath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl. 6","key":"10.1016\/j.etap.2013.11.029_bib0005","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1289\/ehp.961041277","article-title":"Hematopoietic effects of benzene inhalation assessed by long-term bone marrow culture","volume":"104","author":"Abraham","year":"1996","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0010","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1182\/blood.V44.6.837.837","article-title":"Leukemia in shoe-workers exposed chronically to benzene","volume":"44","author":"Aksoy","year":"1974","journal-title":"Blood"},{"key":"10.1016\/j.etap.2013.11.029_bib0015","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1073\/pnas.0530291100","article-title":"Prospective identification of tumorigenic breast cancer cells","volume":"100","author":"Al-Hajj","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.etap.2013.11.029_bib0020","first-page":"8","article-title":"Comparative study of hemoglobin estimated by Drabkin's and Sahli's methods","volume":"38","author":"Balasubramaniam","year":"1992","journal-title":"J. Postgrad. Med."},{"key":"10.1016\/j.etap.2013.11.029_bib0025","series-title":"Methods of Enzymatic Analysis, vol. 2","first-page":"574","author":"Bergmeyer","year":"1974"},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0030","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3324\/haematol.2012.069385","article-title":"Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?","volume":"98","author":"Beurlet","year":"2013","journal-title":"J. Haematol."},{"key":"10.1016\/j.etap.2013.11.029_bib0035","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"Rapid and sensitive method for the quantization of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.etap.2013.11.029_bib0040","first-page":"7","article-title":"Ethylene oxide: cytogenetic and biochemical studies in persons occupationally exposed","volume":"23","author":"Carballo","year":"1994","journal-title":"Environ. Mol. Mutagen."},{"issue":"6750","key":"10.1016\/j.etap.2013.11.029_bib0045","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1038\/45836","article-title":"Deregulated cyclin E induces chromosome instability","volume":"401","author":"Charles","year":"1999","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.etap.2013.11.029_bib0050","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1093\/carcin\/16.8.1963","article-title":"Synergistic increase in chromosomal breakage within the euchromatin induced by an interaction of the benzene metabolites phenol and hydroquinone in mice","volume":"16","author":"Chen","year":"1995","journal-title":"Carcinogenesis"},{"issue":"20","key":"10.1016\/j.etap.2013.11.029_bib0055","doi-asserted-by":"crossref","first-page":"20059","DOI":"10.1074\/jbc.M410670200","article-title":"Curcumin selectively induces apoptosis in deregulated cyclin D1-expressed cells at G2 phase of cell cycle in a p53-dependent manner","volume":"280","author":"Choudhuri","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.etap.2013.11.029_bib0060","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/sj.leu.2403670","article-title":"Animal models of acute myelogenous leukaemia\u2014development, application and future perspectives","volume":"19","author":"Cormack","year":"2005","journal-title":"Leukemia"},{"issue":"3","key":"10.1016\/j.etap.2013.11.029_bib0065","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1080\/15287398209530174","article-title":"Effects of benzene inhalation on murine pluripotent stem cells","volume":"9","author":"Cronkite","year":"1982","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.etap.2013.11.029_bib0070","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/0041-008X(84)90219-9","article-title":"Benzene inhalation produces leukemia in mice","volume":"75","author":"Cronkite","year":"1984","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0075","first-page":"129","article-title":"Benzene hematotoxicity and leukemogenesis","volume":"12","author":"Cronkite","year":"1986","journal-title":"Blood Cells"},{"key":"10.1016\/j.etap.2013.11.029_bib0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1289\/ehp.898297","article-title":"Hematotoxicity and carcinogenicity of inhaled benzene","volume":"82","author":"Cronkite","year":"1989","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0085","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/stem.5530120107","article-title":"The use of animal models in cancer drug discovery and development","volume":"12","author":"Curt","year":"1994","journal-title":"Stem Cells"},{"key":"10.1016\/j.etap.2013.11.029_bib0090","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1182\/blood.V78.3.624.624","article-title":"Gene transfer into normal human hematopoietic cells using in vitro and in vivo assays","volume":"78","author":"Dick","year":"1991","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0095","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0041-008X(87)90196-7","article-title":"An interaction of benzene metabolites reproduces the myelotoxicity observed with benzene exposure","volume":"91","author":"Eastmond","year":"1987","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.etap.2013.11.029_bib0100","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/faat.1997.2293","article-title":"Benzene-induced hematotoxicity and bone marrow compensation in B6C3F1 mice","volume":"36","author":"Farris","year":"1997","journal-title":"Fundam. Appl. Toxicol."},{"issue":"4","key":"10.1016\/j.etap.2013.11.029_bib0105","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1006\/faat.1993.1061","article-title":"Carcinogenicity of inhaled benzene in CBA mice","volume":"20","author":"Farris","year":"1993","journal-title":"Fundam. Appl. Toxicol."},{"issue":"3","key":"10.1016\/j.etap.2013.11.029_bib0110","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1080\/09553009214552161","article-title":"Single-cell gel electrophoresis applied to the analysis of UV-C damage and its repair in human cells","volume":"62","author":"Gedik","year":"1992","journal-title":"Int. J. Radiat. Biol."},{"issue":"3","key":"10.1016\/j.etap.2013.11.029_bib0115","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/0041-008X(81)90102-2","article-title":"Acute and chronic dose\/response effects of inhaled benzene on multipotential hematopoietic stem (CFU-S) and granulocyte\/macrophage progenitor (GM-CFU-C) cells in CD-1 mice","volume":"58","author":"Green","year":"1981","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"3","key":"10.1016\/j.etap.2013.11.029_bib0120","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0950-3536(09)90004-X","article-title":"Minimal residual disease in acute leukaemia: preclinical studies in a relevant rat model (BNML)","volume":"4","author":"Hagenbeek","year":"1991","journal-title":"Baillieres Clin. Haematol."},{"key":"10.1016\/j.etap.2013.11.029_bib0130","first-page":"125","article-title":"Multiple-site; carcinogenicity of benzene in Fischer 344 rats and B6C3F1 mice","volume":"82","author":"Huff","year":"1989","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0135","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1126\/science.2904703","article-title":"Engraftment of immune-deficient mice with human hematopoietic stem cells","volume":"242","author":"Kamel-Reid","year":"1988","journal-title":"Science"},{"issue":"Suppl.","key":"10.1016\/j.etap.2013.11.029_bib0140","first-page":"71","article-title":"Benzene inhalation induced an early onset and a high incidence of leukemias in the p53 deficient C57BL\/6 mice","volume":"92","author":"Kawasaki","year":"2001","journal-title":"Jpn. J. Cancer Res."},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0145","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.beha.2006.10.006","article-title":"Is secondary leukemia an independent poor prognostic factor in acute myeloid leukemia?","volume":"20","author":"Larson","year":"2007","journal-title":"Best Pract. Res. Clin. Haematol."},{"key":"10.1016\/j.etap.2013.11.029_bib0150","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/MCB.18.2.753","article-title":"Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin CDK complexes","volume":"18","author":"Lundberg","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.etap.2013.11.029_bib0155","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1289\/ehp.8982109","article-title":"Benzene, an experimental multipotential carcinogen: results of the long-term bioassays performed at the Bologna Institute of Oncology","volume":"82","author":"Maltoni","year":"1989","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0160","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.cell.2004.08.002","article-title":"Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6","volume":"118","author":"Malumbres","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.etap.2013.11.029_bib0165","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1126\/science.2971269","article-title":"The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function","volume":"241","author":"McCune","year":"1988","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.etap.2013.11.029_bib0170","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/sj.leu.2403670","article-title":"Animal models of acute myelogenous leukaemia development, application and future perspectives","volume":"19","author":"McCormack","year":"2005","journal-title":"Leukemia"},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0175","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/0255-0857.19895","article-title":"Evaluation of different methods for diagnosis of P. falciparum malaria","volume":"24","author":"Mendiratta","year":"2006","journal-title":"Indian J. Med. Microbiol."},{"key":"10.1016\/j.etap.2013.11.029_bib0180","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(92)90030-G","article-title":"RAG-1-deficient mice have no mature B and T lymphocytes","volume":"68","author":"Mombaerts","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.etap.2013.11.029_bib0185","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/353509c0","article-title":"Break for SCIDs","volume":"353","author":"Mosier","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.etap.2013.11.029_bib0190","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/335256a0","article-title":"Transfer of a functional human immune system to mice with severe combined immunodeficiency","volume":"335","author":"Mosier","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.etap.2013.11.029_bib0195","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1097\/00002371-199210000-00011","article-title":"The use of Rosenberg SA congenitally immunodeficient mice to study human tumor metastases and immunotherapy","volume":"12","author":"Mule","year":"1992","journal-title":"J. Immunother."},{"key":"10.1016\/j.etap.2013.11.029_bib0200","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1002\/ajh.20934","article-title":"Benzene-induced acute myeloid leukemia: a clinician's perspective","volume":"82","author":"Natelson","year":"2007","journal-title":"Am. J. Hematol."},{"key":"10.1016\/j.etap.2013.11.029_bib0210","first-page":"717","article-title":"Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice","volume":"50","author":"Price","year":"1990","journal-title":"Cancer Res."},{"key":"10.1016\/j.etap.2013.11.029_bib0215","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1289\/ehp.961041381","article-title":"Leukaemia mortality by cell type in petroleum workers with potential exposure to benzene","volume":"104","author":"Rabble","year":"1996","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0220","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nature05384","article-title":"Identification and expression of human colon cancer-initiating cells","volume":"445","author":"Ricci-Vitini","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.etap.2013.11.029_bib0225","series-title":"Clinical Methods: The History, Physical, and Laboratory Examinations","article-title":"Red cell indices","author":"Sarma","year":"1990"},{"key":"10.1016\/j.etap.2013.11.029_bib0230","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/0971-6580.68341","article-title":"Beneficial effects of Tinospora cordifolia on blood profiles in male mice exposed to lead","volume":"17","author":"Sharma","year":"2010","journal-title":"Toxicol. Int."},{"key":"10.1016\/j.etap.2013.11.029_bib0235","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/0092-8674(92)90029-C","article-title":"RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement","volume":"68","author":"Shinkai","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.etap.2013.11.029_bib0240","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/nature03128","article-title":"Identification of human brain tumor initiating cells","volume":"432","author":"Singh","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.etap.2013.11.029_bib0245","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","article-title":"A simple technique for quantitation of low levels of DNA damage in individual cells","volume":"175","author":"Singh","year":"1988","journal-title":"Exp. Cell Res."},{"issue":"Suppl.","key":"10.1016\/j.etap.2013.11.029_bib0250","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1600-0609.1996.tb01655.x","article-title":"T Overview of benzene-induced aplastic anaemia","volume":"57","author":"Smith","year":"1996","journal-title":"Eur. J. Haematol."},{"issue":"6","key":"10.1016\/j.etap.2013.11.029_bib0255","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1289\/ehp.961041219","article-title":"The mechanism of benzene-induced leukemia: a hypothesis and speculations on the causes of leukemia","volume":"104","author":"Smith","year":"1996","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0260","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1289\/ehp.898223","article-title":"Peroxidase-dependent metabolism of benzene's phenolic metabolites and its potential role in benzene toxicity and carcinogenicity","volume":"82","author":"Smith","year":"1989","journal-title":"Environ. Health Perspect."},{"issue":"1\u20132","key":"10.1016\/j.etap.2013.11.029_bib0265","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.cbi.2011.02.010","article-title":"Benzene, the exposome and future investigations of leukemia etiology","volume":"192","author":"Smith","year":"2011","journal-title":"Chemico-Biol. Interact."},{"key":"10.1016\/j.etap.2013.11.029_bib0270","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0041-008X(80)90202-1","article-title":"The inhalation toxicology of benzene: Incidence of hematopoietic neoplasms and hematotoxicity in ARK\/J and C57BL\/6J mice","volume":"54","author":"Snyder","year":"1980","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"1","key":"10.1016\/j.etap.2013.11.029_bib0275","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0300-483X(90)90035-F","article-title":"Phenol-induced stimulation of hydroquinone bioactivation in mouse bone marrow in vivo: possible implications in benzene myelotoxicity","volume":"62","author":"Subrahmanyam","year":"1990","journal-title":"Toxicology"},{"key":"10.1016\/j.etap.2013.11.029_bib0280","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0165-1218(96)90063-4","article-title":"Benzene induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition","volume":"368","author":"Tuo","year":"1996","journal-title":"Mutat. Res."},{"key":"10.1016\/j.etap.2013.11.029_bib0285","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1124\/mol.65.5.1225","article-title":"Oral exposure to benzo[a] pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation","volume":"65","author":"Uno","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.etap.2013.11.029_bib0290","series-title":"WHO Classification of Tumours: Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues","first-page":"18","article-title":"Introduction and overview of the classify cation of the myeloid neoplasms","author":"Vardiman","year":"2008"},{"key":"10.1016\/j.etap.2013.11.029_bib0295","first-page":"63","article-title":"Cytologic and cytogenetic effects of benzene","volume":"2","author":"Wolman","year":"1977","journal-title":"J. Toxicol. Environ. Health Suppl."},{"key":"10.1016\/j.etap.2013.11.029_bib0300","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.cbi.2009.12.022","article-title":"Benzene-induced bone-marrow toxicity: a hematopoietic stem-cell-specific, aryl hydrocarbon receptor-mediated adverse effect","volume":"184","author":"Hirabayashi","year":"2010","journal-title":"Chemico-Biol. Interact."},{"key":"10.1016\/j.etap.2013.11.029_bib0305","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S0301-472X(00)00671-8","article-title":"Mechanism of action of benzene toxicity: cell cycle suppression in hemopoietic progenitor cells (CFU-GM)","volume":"29","author":"Yoon","year":"2001","journal-title":"Exp. Hematol."},{"issue":"11","key":"10.1016\/j.etap.2013.11.029_bib0310","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1289\/ehp.6164","article-title":"Mechanisms of benzene-induced hematotoxicity and leukemogenicity: cDNA microarray analyses using mouse bone marrow tissue","volume":"111","author":"Yoon","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.etap.2013.11.029_bib0315","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1101\/gad.1771409","article-title":"Mouse models of human AML accurately predict chemotherapy response","volume":"23","author":"Zuber","year":"2009","journal-title":"Genes Dev."}],"container-title":["Environmental Toxicology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668913002706?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1382668913002706?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T04:02:48Z","timestamp":1716350568000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1382668913002706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S1382668913002706"],"URL":"https:\/\/doi.org\/10.1016\/j.etap.2013.11.029","relation":{},"ISSN":["1382-6689"],"issn-type":[{"value":"1382-6689","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Physiologically based toxicokinetic modeling of secondary acute myelolytic leukemia","name":"articletitle","label":"Article Title"},{"value":"Environmental Toxicology and Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.etap.2013.11.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}